Nos projets de recherche
Disponible en anglais seulement
Mise à jour février 2025
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Title | Principal Investigator / Supervisor | Program Trier par ordre décroissant | Project Start Date | Project End Date | Total $ Awarded |
---|---|---|---|---|---|
Assessing the relationship between red blood cell deformability and transfusion lifetime | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: LAMOUREUX, Erik |
Graduate Fellowship Program | $122,000 | ||
Dengue virus replication by anucleate cells: impact on pathogen reduction efficacy | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: FELGENHAUER, Ulrike |
Graduate Fellowship Program | $52,000 | ||
Deformability based cell sorting enabling quality control of stored red blood cells | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: ISLAMZADA, Emel |
Graduate Fellowship Program | $112,333 | ||
Defining the stem cell regulatory functions of GAS6 and FTO | Principal Investigator: MAGANTI, Harinad Co-Investigator(s) / Trainee: PASALA, Ajay |
Graduate Fellowship Program | $122,000 | ||
Identification of protein biomarkers for red cell quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: CHEN, Deborah |
Graduate Fellowship Program | $100,000 | ||
Platelet desialylation: novel mechanism of platelet clearance and immune tolerance | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: LI, June |
Graduate Fellowship Program | $104,000 | ||
A novel clot-dissolving agent derived from clotting factor Va | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: LEE, Frank |
Graduate Fellowship Program | $39,500 | ||
Generation of a coagulation factor-based thrombotic agent | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: WITT, Alexandra |
Graduate Fellowship Program | $122,000 | ||
The in vivo effects of liposome treatment on minimizing membrance injury in rat red blood cells during hypothermic storage | Principal Investigator: HOLOVATI, Jelena Co-Investigator(s) / Trainee: da SILVIERA CAVALCANTE, Luciana |
Graduate Fellowship Program | $100,000 | ||
Small molecule ice recrystallization inhibitors as cryo-additives for red blood cell cryopreservation | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: POISSON, Jessica |
Graduate Fellowship Program | $82,000 | ||
Monoclonal antibodies with anti-D like activity in amelioration of murine ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: KHAN, Ramsha |
Graduate Fellowship Program | $52,000 | ||
Modified platelet storage containers to improve quality during storage | Principal Investigator: KIZHAKKEDATHU, Jayachandran Co-Investigator(s) / Trainee: PEREYRA DOS SANTOS, Nicolas |
Graduate Fellowship Program | $122,000 | ||
MRI guided focused ultrasound facilitated IVIg immunotherapy as a therapeutic approach for Alzheimer's disease | Principal Investigator: AUBERT, Isabelle Co-Investigator(s) / Trainee: DUBEY, Sonam |
Graduate Fellowship Program | $100,000 | ||
Improving pathogen inactivation: the dengue virus-induced platelet proteome | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: TEGEGN, Tseday Zewdu |
Graduate Fellowship Program | $104,000 | ||
New solution for cord blood unit preservation | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: KAUSHAL, Richa |
Graduate Fellowship Program | $116,500 | ||
CD71 Erythroid Cells, RBC Clearance and Sepsis in Donor - Recipient Sex- Mismatched Transfusion | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: LI, Wenhui |
Graduate Fellowship Program | $70,000 | ||
Fc receptor blockade related to fetal and neonatal alloimmune thrombocytopenia | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: TAWHIDI, Zoya |
Graduate Fellowship Program | $70,000 | ||
Characterization of the role of MSI2 in human hematopoietic stem cell self-renewal | Principal Investigator: HOPE, Kristin Co-Investigator(s) / Trainee: RENTAS, Stefan |
Graduate Fellowship Program | $100,000 | ||
Studying and alleviating the effects of platelet microparticles induced by pathogen reduction of platelet concentrates | Principal Investigator: PROVOST, Patrick Co-Investigator(s) / Trainee: LAUGIER, Jonathan |
Graduate Fellowship Program | $52,000 | ||
Synthesis and live cell imaging of ice recrystallization inhibitors in red blood cells | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: MCMUNN, Leah |
Graduate Fellowship Program | $112,333 | ||
Anemia-induced bleeding in thrombocytopenic patients with blood cancer | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: MODI, Dimpy |
Graduate Fellowship Program | $70,000 | ||
Replacing plasma-derived C1 Esterase inhibitor | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: SIVANANTHAN, Sangavi |
Graduate Fellowship Program | $70,000 | ||
Investigation of pathophysiology, prevention and treatment of murine Transfusion Related Acute Lung Injury (TRALI) | Principal Investigator: SEMPLE, John Co-Investigator(s) / Trainee: McVEY, Mark |
Graduate Fellowship Program | $52,000 | ||
Investigating the mechanism of anti-CD44 antibody amelioration of IVIg-treatable disease | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NORRIS, Peter |
Graduate Fellowship Program | $104,000 | ||
Replacement of IVIg by small molecule inhibitors of phagocytosis | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: LORIAMINI, Melika |
Graduate Fellowship Program | $112,333 | ||
Management of critical bleeding in patients with immune thrombocytopenia | Principal Investigator: GUYATT, Gordon Co-Investigator(s) / Trainee: CHOWDHURY, Saifur |
Graduate Fellowship Program | $70,000 | ||
Cellular therapy to improve CD4+ T-Cell responses in humanized mice infected with HIV-1: adoptive transfer of CD4+ T-cells lacking s-Src activity | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: McCARTHY, Stephen |
Graduate Fellowship Program | $96,000 | ||
Novel cell-surface engineering methods to increase immune-tolerance of allogenic cell transplantation | Principal Investigator: KIZHAKKEDATHU, Jayachandran Co-Investigator(s) / Trainee: MOON, Haisle |
Graduate Fellowship Program | $82,000 | ||
Transcriptome analyses of Staphylococcus aureus grown in platelet concentrates with focus on virulence | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: DA SILVA PAREDES, Carina |
Graduate Fellowship Program | $122,000 | ||
External validation of a prediction model for diagnosing immune thrombocytopenia | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: MAHAMAD, Syed |
Graduate Fellowship Program | $70,000 | ||
Impact of storage on the function of cord blood hematopoietic stem and progenitor cells | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: JAHAN, Suria |
Graduate Fellowship Program | $104,000 | ||
A multifaceted intervention to optimize red blood cell transfusion practice in two provinces | Principal Investigator: WEBERT, Kathryn Co-Investigator(s) / Trainee: NAHIRNIAK, Susan, CALLUM, Jeannie, LIN, Yulia, ZELLER, Michelle |
Intramural Research Grant Program | $332,942 | ||
The threshold or operative hemoglobin trigger for red blood cell transfustion pilot trial (TOPGUN-pilot) | Principal Investigator: MARTEL, Guillaume Co-Investigator(s) / Trainee: MCISAAC, Daniel, FERGUSSON, Dean, TINMOUTH, Alan, BREAU, Rodney, CARRIER, Francois Martin, VERRET, Michael, TALJAARD, Monica, BROUSSEAU, Karine |
Intramural Research Grant Program | $400,000 | ||
IN-TRUST: Using a transfusion database to explore the immune-modulatory impacts of blood transfusion and the clinical impacts of blood processing changes | Principal Investigator: NING, Shuoyan Co-Investigator(s) / Trainee: ARNOLD, Donald, ZELLER, Michelle, ACKER, Jason, LI, Na, HEDDLE, Nancy, HILLIS, Christopher, ROCHWERG, Bram, SYED, Summer |
Intramural Research Grant Program | $270,352 | ||
Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial | Principal Investigator: GRAMMATOPOULOS, George Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent |
Intramural Research Grant Program | $276,081 | ||
Improving blood product quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: MA, Hongshen, JOHNSON, James, D'ALESSANDRO, Angelo |
Intramural Research Grant Program | $304,462 | ||
Optimization of monoclonal anti-erythrocyte antibodies for improved immunoprophylaxis in a murine model | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu |
Intramural Research Grant Program | $400,000 | ||
Accelerating the clinical translation of “off the shelf” NK cell products for immunotherapies | Principal Investigator: MAGANTI, Harinad Co-Investigator(s) / Trainee: JEZIERSKI, Anna, ALLAN, David |
Intramural Research Grant Program | $300,000 | ||
Modulation of biofilm formation, virulence, and antimicrobial resistance by Staphylococcus aureus during platelet storage | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: SAD, Subash, MAH, Thien-Fah |
Intramural Research Grant Program | $323,253 | ||
Controlling coagulopathy and bleeding in a mouse model of hemorrhagic shock | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: NAZY, Ishac |
Intramural Research Grant Program | $274,854 | ||
Influence of eryptosis and storage on transfused red cell recovery in sepsis | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: BRANCH, Donald, LIAW, Patricia, HEDDLE, Nancy, QADRI, Syed |
Intramural Research Grant Program | $283,569 | ||
Facilitating RBC-mediated Nitric Oxide Release and Boosting Antioxidant Capacity during Ex Vivo Heart Perfusions as a Strategy to Improve Oxygen Delivery | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: FREED, Darren |
Intramural Research Grant Program | $377,997 | ||
New cryosolution for stem cell-based therapeutics | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: BEN, Robert, HARPER, Marie-Ellen, CHAKRABORTY, Nilay |
Intramural Research Grant Program | $180,000 | ||
Residual risk of transfusion-transmitted cytomegalovirus infection: incidence and pathogenesis | Principal Investigator: PREIKSAITIS, Jutta Co-Investigator(s) / Trainee: O'BRIEN, Sheila F., FEARON, Margaret, NAHIRNIAK, Susan |
Intramural Research Grant Program | $260,451 | ||
Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy |
Intramural Research Grant Program | $200,000 | ||
Monovalent Fc receptor blockade using novel fusion proteins: The road towards an IVIg replacement | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SHEFFIELD, William, BRANCH, Donald |
Intramural Research Grant Program | $400,000 | ||
Improving platelet storage and blood transfusion: unveiling the role of apolipoprotein A-IV | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: LAZARUS, Alan, BRANCH, Donald |
Intramural Research Grant Program | $400,000 | ||
Enabling next generation hematopoietic-based therapeutics and manufacturing | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: MCCOMB, Scott, JEZIERSKI, Anna, MAGALHAES, Ana, IQBAL, Umer |
Intramural Research Grant Program | $300,000 | ||
Antibodies to CD44 as a potential replacement for IVIg in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SEMPLE, John W., SHEFFIELD, William |
Intramural Research Grant Program | $300,000 | ||
Fc receptor blockade in transfusion medicine | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu, GUPTA, Akash, SHEHATA, Nadine, KJELDSEN-KRAGH, Jens, NEWMAN, Peter J., CSERTI-GAZDEWICH, Christine, RAVETCH, Jeffery |
Intramural Research Grant Program | $400,000 |