Alan Lazarus

Selected Publications
  1. Lazarus AH: ResearchUnit: Single site solution: Engineering novel antibodies for the treatment of ITP (PDF) 2015; Blood.ca website.
  2. Yu X, Menard M, Prechl J, Bhakta V, Sheffield WP, Lazarus AH. Monovalent Fc receptor blockade by an anti-Fcγ receptor-albumin fusion protein ameliorates murine ITP with abrogated toxicity. Blood; doi: blood-2015-08-664656. [Epub ahead of print]
  3. Campbell IK, Miescher S, Branch DR, Mott PJ, Lazarus AH, Han D, Maraskovsky E, Zuercher AW, Neschadim A, Leontyev D, McKenzie BS, Käsermann F: Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils. The J Immunol 2014; 192:5031-5038.
  4. Chen X, Ghaffar H, Jen CC, Lazarus AH: Antibody specific for the glycophorin A complex mediates intravenous immune globulin–resistant anemia in a murine model. Transfusion 2014; 54:655-664.
  5. Lazarus AH: ResearchUnit: Research into TRALI therapies generates results that are a TAD interesting! 2014; Blood.ca website.
  6. Crow AR, Yu H, Han D, Lazarus AH: Amelioration of Murine Passive Immune Thrombocytopenia by IVIg and a Therapeutic Monoclonal CD44 Antibody Does Not Require the Myd88 Signaling Pathway. PLoS One 2013; 8:e71882.
  7. Lazarus AH: Monoclonal versus polyclonal anti-D in the treatment of ITP. Expert Opin Biol Th 2013; 13:1353-1356.
  8. Semple JW, Kim M, Hou J, McVey M, Lee YJ, Tabuchi A, Kuebler WM, Chai Z-W, Lazarus AH: Intravenous immunoglobulin prevents murine antibody-mediated acute lung injury at the level of neutrophil reactive oxygen species (ROS) production. PLoS One 2012; 7:e31357.
  9. Crow AR, Suppa SJ, Chen X, Mott PJ, Lazarus AH. The neonatal Fc receptor (FcRn) is not required for IVIg or anti-CD44 monoclonal antibody–mediated amelioration of murine immune thrombocytopenia. Blood 2011; 118:6403-6406.

Autres distinctions

Click to see Leadership Roles:
2015Prix Tibor Greenwalt Memorial remis par l'American Association of Blood Banks
Depuis 2013Membre du comité d'évaluation par les pairs de l'hôpital St. Michael’s
Depuis 2011Président du comité de la protection des animaux, hôpital St. Michael's
De 2011 à 2014Président du comité de la protection des animaux, Toronto Centre for Phenogenomics