Mastering the monocyte monolayer assay

What is this research about?

Serious adverse reactions to incompatible blood are caused by antibody–antigen interactions: if the recipient’s antibodies recognize an antigen on the surface of transfused blood cells, they bind to the antigen, which flags the blood cells for destruction by the recipient’s immune cells and can cause illness due to severe anemia. Similar reactions can occur in patients receiving other blood products, such as the plasma-derived drug intravenous immunoglobulin (IVIG).

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