Collected in Jan 2017
What is this research about?
Blood clots are necessary to control bleeding; however, too much clotting can be harmful. Heart attacks and stroke, which are leading causes of death around the world, are often caused by clots blocking the flow of blood to the heart and brain.
Blood clots in the body are normally broken up by the clot-dissolving enzyme, plasmin. Plasmin is generated when its inactive form, plasminogen, is activated by an enzyme called tissue plasminogen activator (tPA). Nearly three decades ago, tPA produced in the lab (recombinant tPA; rtPA)...