Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y 2022 Clin Transl Immunol View Researchers New or improved product or process
SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia Appelbaum J, Arnold DM, Kelton JG, Gernsheimer T, Jevtic SD, Ivetic N, Smith JW, Nazy I 2022 Blood Adv View Researchers Basic research
U.S. cities will not meet blood product resuscitation standards during major mass casualty incidents: Results of a THOR-AABB working party prospective analysis Cannon JW, Igra NM, Borge PD, Cap AP, Devine D, Doughty H, Geng Z, Guzman JF, Ness PM, Jenkins DH, Rajbhandary S, Schmulevich D, Stubbs JR, Wiebe DJ, Yazer MH, Spinella PC 2022 Transfusion View Health care providers Clinical research
Applying principles of patient blood management during COVID-19 pandemic: a literature review Khandelwal A, Vandermeulen H, Tordon B, Pavenski K 2022 Annals of Blood View Health care providers Clinical research
NAC Statement on RHD Genotyping in Prenatal Patients Pavenski K, Khandelwal A, Clarke G, Lane D 2022 National Advisory Committee on Blood and Blood Products View Health care providers Benchmarking and standard setting
Babesia microti in a Canadian blood donor and lookback in a red blood cell recipient Drews SJ, Van Caeseele P, Bullard J, Lindsay LR, Gaziano T, Zeller MP, Lane D, Ndao M, Allen VG, Boggild AK, O'Brien SF, Marko D, Musuka C, Almiski M, Bigham M 2022 Vox Sang View Health care providers Clinical research
Hemolysis after high-dose intravenous immunoglobulin: An under-appreciated sequelae Branch DR, Almizraq RJ, Bussel JB 2022 Am J Hematol View Researchers Basic research
Prolonged Blood Storage and Risk of Posttransfusion Acute Kidney Injury Adegboye J, Sapatnekar S, Mascha EJ, Shah K, Lioudis M, Essber H, Cohen B, Rivas E, Heddle NM, Eikelboom JW, Ellis MH, Sharon Y, Sinha R, Kurz A, Sessler DI 2022 Anesthesiology View Researchers Clinical research
Chapter 19. Pathogen-reduced platelets Blais-Normandin I, Tordon B, Anani W, Ning S 2022 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Lessons Learned from the COVID-19 Pandemic and How Blood Operators Can Prepare for the Next Pandemic Drews SJ, O’Brien SF 2022 Viruses View Blood operators New or improved product or process
A critical contribution in a time of crisis: Examining motivations and deterrents to COVID-19 convalescent plasma donation and future donation intentions among prospective Canadian donors Holloway K, Campbell C, Ali R, Huyer LD, Hart D, Haw J, Brennenstuhl S, Grundy Q 2022 Transfus Med View Researchers Ethical, legal & social implications research
Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation Olafson C, William N, Howell A, Beaudin L, Gill B, Clarke G, Stephens S, Lopes-Carvalho D, Lane D, Schubert P, McTaggart K, Acker JP 2022 Transfusion View Researchers New or improved product or process
Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood Stewart T 2022 Blood.ca website View Health care providers Benchmarking and standard setting
ResearchUnit: Risk of HIV did not change with expanding eligibility criteria for gay, bisexual and other men who have sex with men Walsh G 2022 Blood.ca website View Regulators MSM research
Inductively-Coupled Plasma Mass Spectrometry-Novel Insights From an Old Technology Into Stressed Red Blood Cell Physiology Stephenson D, Nemkov T, Qadri SM, Sheffield WP, D'Alessandro A 2022 Front Physiol View Researchers Basic research
Utilization of a surgical database to provide care and assess perioperative treatment and outcomes in patients with bleeding disorders Olasupo OO, Haddix C, Nakar C, Maahs J, Greist A, Ghafoor A, Donfield SM, Iorio A, Shapiro AD 2022 Eur J Haematol View Health care providers Benchmarking and standard setting
HIV incidence and compliance with deferral criteria over three progressively shorter time deferrals for men who have sex with men in Canada Caffrey N, Goldman M, Osmond L, Yi Q-L, Fan W, O'Brien SF 2022 Transfusion View Regulators MSM research
Transfusion thresholds in myelodysplastic syndrome - Helping patients live better Balitsky A, Arnold D 2022 Transfusion View Health care providers Clinical research
A cross-sectional study of haemolytic disease of the newborn in Uganda Dhabangi A, Nankunda J, Okaba V, Nakubulwa S, Hume HA, Dzik WH, Heddle NM 2022 Vox Sang View Health care providers Clinical research
The Cost Effectiveness of Axicabtagene Ciloleucel Versus Best Supportive Care in the Treatment of Adult Patients with Relapsed or Refractory Large B-Cell Lymphoma (LBCL) After Two or More Lines of Systemic Therapy in Canada Hillis C, Vicente C, Ball G 2022 Pharmacoeconomics View Researchers Clinical research
The Missing Pieces to the Cold-Stored Platelet Puzzle Zhao H, Devine DV 2022 Int J Mol Sci View Researchers Basic research
The evaluation of constant coronary artery flow versus constant coronary perfusion pressure during normothermic ex situ heart perfusion Qi X, Hatami S, Bozso S, Buchko M, Forgie KA, Olafson C, Khan M, Himmat S, Wang X, Nobes DS, Acker JP, Nagendran J, Freed DH 2022 J Heart Lung Transplant View Researchers Basic research
Summary of adverse transfusion reactions 2017-2022 Yan M 2022 Blood.ca website View Blood operators Benchmarking and standard setting
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS 2022 Cytotherapy View Researchers Clinical research
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup 2022 Vox Sang View Researchers Benchmarking and standard setting
Vaccine-induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources Greinacher A, Langer F, Makris M, Pai M, Pavord S, Tran H, Warkentin TE 2022 J Thromb Haemost View Health care providers Clinical research
Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination Breznik JA, Huynh A, Zhang A, Bilaver L, Bhakta H, Stacey HD, Ang JC, Bramson JL, Nazy I, Miller MS, Denburg J, Costa AP, Bowdish DME 2022 J Immunol View Health care providers Clinical research
THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets Gil Gonzalez L, Fernandez-Marrero Y, Norris PAA, Tawhidi Z, Shan Y, Cruz-Leal Y, Won KD, Frias-Boligan K, Branch DR, Lazarus AH 2022 PLoS One View Researchers Basic research
ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM 2022 Blood View Researchers Basic research
Chapter 5. Concentrates for hemostatic disorders and hereditary angioedema Poon MC, Goodyear D, Rydz N, Lee A 2022 Clinical Guide to Transfusion View Health care providers Benchmarking and standard setting
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Benchmarking and standard setting
Cost-effectiveness of eltrombopag vs intravenous immunoglobulin for the perioperative management of immune thrombocytopenia Kaur MN, Arnold DM, Heddle NM, Cook RJ, Hsia C, Blostein M, Jamula E, Sholzberg M, Lin Y, Kassis J, Larratt L, Tinmouth A, Carruthers J, Li N, Liu Y, Xie F 2022 Blood Adv View Health care providers Clinical research
Loss of repeat convalescent plasma donors due to waning anti-SARS-CoV-2 plaque reduction neutralization test titers (April-December 2020) Drews S, Devine D, McManus J, Mendoza E, Manguiat K, Girardin R, Dupuis A, McDonough K, Lin J, Evans D, Pambrun C, Drebot M, Wood H 2022 Transfus Med Rev View Blood operators New or improved product or process
Plaquettes extraites de la couche leucoplaquettaire à teneur réduite en agents pathogènes Blais-Normandin I, Tordon B, Anani W 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Methods to Evaluate the Potential Clinical Significance of Antibodies to Red Blood Cells Boligan KF, Sandhu G, Branch DR 2022 Curr Protoc View Researchers Benchmarking and standard setting
Management of immune‐mediated thrombocytopenia Gabe C, Arnold D, Smith J, T W 2022 Rossi's Principles of Transfusion Medicine View Health care providers Benchmarking and standard setting
Why We Swab: A library of stories in stem cell donation Jagelaviciute G, Kum E, Li EW, Rosenfeld A, Williams K, Kandel R, DeGurse N, Park B, Okonofua S, Sano L, Gerofsky M, Sharp A, Hatkar R, Thyagu S, Fingrut WB 2022 Transfusion View Health care providers Ethical, legal & social implications research
Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 Viruses Lin Y-CJ, Evans DH, Robbins NF, Orjuela G, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Yi Q-L, O’Brien SF, Drews SJ 2022 Microbiol Spectr View Health care providers Benchmarking and standard setting
Les fournisseurs de sang canadiens : un rôle croissant dans la surveillance de la santé publique? O’Brien SF, Drews SJ, Lewin A, Osiowy C, Drebot MA, Renaud C 2022 Relevé des maladies transmissibles au Canada View Health care providers New or improved product or process
Circulaire d'information utilisation de composants sanguins humains: Plaquettes Stewart T 2022 Blood.ca website View Health care providers Benchmarking and standard setting
Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies Gajic-Veljanoski O, Li C, Schaink AK, Guo J, Shehata N, Charames GS, de Vrijer B, Clarke G, Pechlivanoglou P, Okun N, Kandel R, Dooley J, Higgins C, Ng V, Sikich N 2022 Transfusion View Researchers Clinical research
HIV residual risk in Canada for apheresis source plasma donation without deferral for men who have sex with men Aubé E, Lewin A, O'Brien SF, Grégoire Y, Pillonel J, Steele WR, Custer B, Davison KL, Germain M, Seed CR, Camirand Lemyre F, the Surveillance RA, Policy Subgroup of the ISBT Transfusion Transmitted Infectious Diseases Working Party 2022 Vox Sang View Blood operators MSM research
The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults Asamoah-Boaheng M, Goldfarb DM, Karim ME, O’Brien SF, Wall N, Drews SJ, Barakauskas V, Jassem AN, Grunau B 2022 J Infect Dis View Researchers Clinical research
HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA 2022 Transfusion View Researchers MSM research
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia Li N, Mahamad S, Parpia S, Iorio A, Foroutan F, Heddle NM, Hsia CC, Sholzberg M, Rimmer E, Shivakumar S, Sun HL, Refaei M, Hamm C, Arnold DM 2022 J Thromb Haemost View Researchers New or improved product or process
Surveillance report O'Brien SF 2022 Blood.ca website View Blood operators Benchmarking and standard setting
Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex Sask KN, Thong B, Goodarzynejad N, Berry LR, Chan AKC 2022 Biointerphases View Researchers Basic research
GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach Zeng L, Brignardello-Petersen R, Hultcrantz M, Mustafa RA, Murad MH, Iorio A, Traversy G, Akl EA, Mayer M, Schünemann HJ, Guyatt GH 2022 J Clin Epidemiol View Researchers Clinical research
A mixed methods investigation of the relationship between blood donor policy, interest in donation, and willingness to donate among gay, bisexual, and other men who have sex with men in Ontario, Canada Armstrong JP, Brennan DJ, Collict D, Kesler M, Bekele T, Souleymanov R, Grace D, Lachowsky NJ, Hart TA, Adam BD 2022 BMC Public Health View Researchers MSM research
Staff perspectives on barriers and enablers to implementing alternative source plasma eligibility criteria for gay, bisexual, and other men who have sex with men Castillo G, Vesnaver E, Gibson E, Butler-Foster T, Goldman M, Hill NE, Rosser A, Lapierre D, Rubini KA, MacDonagh R, Miguel G, Palumbo A, MacPherson P, Randall T, Osbourne-Sorrell W, O'Brien SF, Bridel W, Otis J, Greaves M, Al-Bakri TB, Reid M, Labrecque M, Germain M, Orvis S, Clapperton AT, Devine D, Presseau J 2022 Transfusion View Blood operators MSM research