Our Funded Research Projects

Updated April 2019

Title Principal Investigator / Supervisor Program Project Start Date Project End Date Sort ascending Total $ Awarded
Deformability based cell sorting enabling quality control of stored red blood cells Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: ISLAMZADA, EMEL
Graduate Fellowship Program $52,000
Donor characteristics and the quality of red cell concentrates Principal Investigator: ACKER, Jason P

Co-Investigator(s) / Trainee: MYKHAILOVA, Olga
Postdoctoral Fellowship Program $150,000
Novel detection strategies for new platelet ligands and anti-platelet antibodies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: NEVES, Miguel
Postdoctoral Fellowship Program $150,000
Synthesis of carbohydrate derivatives for the improvement of red blood cell storage Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: MEYER, Julia
Graduate Fellowship Program $82,000
Novel cell-surface engineering methods to increase immune-tolerance of allogenic cell transplantation Principal Investigator: KIZHAKKEDATHU, Jayachandran

Co-Investigator(s) / Trainee: MOON, Haisle
Graduate Fellowship Program $82,000
A novel clot-dissolving agent derived from clotting factor Va Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: LEE, Frank
Graduate Fellowship Program $52,000
New solution for cord blood Unit preservation Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: KAUSHAL, Richa
Graduate Fellowship Program $52,000
Monoclonal antibodies with anti-D like activity in amelioration of murine ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: KHAN, RAMSHA
Graduate Fellowship Program $52,000
Investigating the mechanism of anti-CD44 antibody amelioration of IVIg-treatable disease Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NORRIS, Peter
Graduate Fellowship Program $52,000
Monovalent Fc receptor blockade using novel fusion proteins: The road towards an IVIg replacement Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: SHEFFIELD, William, BRANCH, Donald
Intramural Research Grant Program $400,000
Influence of eryptosis and storage on transfused red cell recovery in sepsis Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: BRANCH, Donald, LIAW, Patricia, HEDDLE, Nancy
Intramural Research Grant Program $283,569
Allowing MSM to donate in the context of pathogen reduction of blood components: mathematical modeling of the risk of HIV, HBV and HCV transmission through transfusion Principal Investigator: LEWIN, Antoine

Co-Investigator(s) / Trainee: GERMAIN, Marc, DELAGE, Gilles, ROBILLARD, Pierre, GRÉGOIRE, Yves, WILLIAM, Fraser
MSM Research Grant Program $29,618
Évaluation de l’acceptabilité et de la faisabilité d’un programme de dons de plasma destiné au fractionnement, pour les hommes ayant des relations sexuelles avec d’autres hommes de la communauté gaie montréalaise Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, GODIN, Gaston, PRONOVOST, Frédérick, MONTEITH, Kenneth, MYHAL, Geneviève, GIRARD, Gabriel, MORIN, Michel
MSM Research Grant Program $219,507
Understanding general population impact and opportunities from changes to blood donation deferral screening and criteria for men who have sex with men Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: BRENNAN, David, CARD, Kiffer, DRYDEN, OmiSoore, GASPAR, Mark, GILBERT, Mark, GRACE, Daniel, KNIGHT, Rodney, LEBOUCHÉ, Bertrand, MORGAN, Jeffrey, SALWAY, Travis
MSM Research Grant Program $300,000
Mathematical Modelling – Comparing HIV Risk Between MSM Donation Strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GERMAIN, Marc, GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program $24,000
Feasibility of implementing source plasma donation with alternative eligibility criteria for men who have sex with men Principal Investigator: PRESSEAU, Justin

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, GERMAIN, Marc, DEVINE, Dana, ROSSER, Andrew, LAPIERRE, Don
MSM Research Grant Program $299,950
TAD-POL (Transfusion-Associated-Dyspnea: Prospective observation and laboratory assessment) Principal Investigator: CSERTI-GAZDEWICH, Christine

Co-Investigator(s) / Trainee: BRANCH, Donald, LAZARUS, Alan, CALLUM, Jeannie, LIN, Yulia, PENDERGRAST, Jacob, LIEBERMAN, Lani, SHEHATA, Nadine, PAVENSKI, Katerina, SKEATE, Robert
Intramural Research Grant Program $278,027
The mechanism of action of monoclonal antibody blends in the potential replacement of anti-D in HDFN Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: CRUZ-LEAL, Yoelys
Postdoctoral Fellowship Program $150,000
Optimization of monoclonal anti-erythrocyte antibodies for improved immunoprophylaxis in a murine model Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program $400,000
Development of a small molecule cocktail for the expansion of cord blood stem cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: BLAKE, John, AUDET, Julie
Intramural Research Grant Program $220,000
Evaluating the role of donor characteristics and blood component manufacturing on the quality of red cell concentrates Principal Investigator: ACKER, Jason P

Co-Investigator(s) / Trainee: BRANCH, Donald, CLARKE, Gwen, NAHIRNIAK, Susan
Intramural Research Grant Program $368,873
Estimating the probability of HIV risk in MSM donor policies through biobehavioural and mathematical modelling studies Principal Investigator: HART, Trevor

Co-Investigator(s) / Trainee: LAMBERT, Gilles, GRACE, Daniel, BAUER, Greta, MOORE, David, COX, Joseph, LACHOWSKY, Nathan, MISHRA, Sharmistha, BRENNAN, David, TAN, Darrell
MSM Research Grant Program $400,000
Sex Now 2018: A national survey on blood donation and undiagnosed blood borne infections Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: TRUSSLER, Terry, GILBERT, Mark, SALWAY, Travis, JOLLIMORE, Jody, HAM, David, LOFTUS, Patrick, OLIVER, Brent, HANSEN, Brian, VISSER, Floyd, BRENNAN, David, GRACE, Daniel, OTIS, Joanne, LEBOUCHÉ, Bertrand, NUMER, Matthew, SAXTON, Peter
MSM Research Grant Program $400,000
Of skin, sperm, and blood: A comparative analysis of exemptions in Canadian human tissue legislation Principal Investigator: CATTAPAN, Alana

Co-Investigator(s) / Trainee: VON TIGERSTROM, Barbara, NELSON, Eric, DAWSON, Roseanne
James Kreppner Award Program $43,275
McMaster Centre for Transfusion Research Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee:
Transfusion Medicine Research Program Support Award $1,150,000
ACB and MSM - it's not an oxymoron: A research project that explores the importance of ACB people in MSM blood donation research Principal Investigator: DRYDEN, OmiSoore

Co-Investigator(s) / Trainee: LEE, Woo Jin Edward, NELSON, LaRon, MARSHALL, Zack, MBUAGBAW, Lawrence
MSM Research Grant Program $400,000
University of Toronto QUEST Research Program Principal Investigator: CALLUM, Jeannie

Co-Investigator(s) / Trainee:
Transfusion Medicine Research Program Support Award $1,137,400
Canadians’ Attitudes and Opinions Regarding Cardiac Donation after Cardiocirculatory Death: A mixed-methods study Principal Investigator: BALL, Ian

Co-Investigator(s) / Trainee: WEISS, Matt D'ARAGON, Fred PARSONS LEIGH, Jenna HONARMAND, Kimia BASMAJI, John SIBBALD, Robert
Kenneth J. Fyke Award Program $95,929
Novel mechanisms of platelet aggregation: Roles of non-classical beta-3 integrin ligands and fibronectin in thrombosis and hemostasis Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program $378,675
Expanding treatment options for inflammatory bowel disease: a novel mechanism of antibody-based immunotherapy Principal Investigator: SLY, Laura

Co-Investigator(s) / Trainee: HORWITZ, Marc, BRESSLER, Brian, RASSEKH, Rod, TURVEY, Stuart
Canadian Blood Services-CIHR Partnership Operating Grant Program $387,855
Fetal and neonatal alloimmune thrombocytopenia: novel mechanisms and therapeutic approaches Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program $447,525
Virtual transfusions competency assessment Principal Investigator: VAN VLIET, Paula

Co-Investigator(s) / Trainee: DEYDEY, Kim WESOLOWSKI, Mike
BloodTechNet Award Program $32,795
Small molecule ice recrystallization inhibitors as cryo-additives for red blood cell cryopreservation Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: POISSON, Jessica
Graduate Fellowship Program $82,000
Development of internet modules for serology curriculum delivery Principal Investigator: YAN, Matthew

Co-Investigator(s) / Trainee: PENDERGRAST, Jacob, TAIT, Gordon
BloodTechNet Award Program $35,500
Rapid verification variant D phenotype by genotyping in a regional laboratory Principal Investigator: BERARDI, Philip

Co-Investigator(s) / Trainee: FUNG KEE FUNG, Karen GIULIVI, Antonio NEURATH, Doris CLARKE, Gewn
Blood Efficiency Accelerator Award Program $30,000
Investigating a new class of small molecule ice recrystallization inhibitors for red blood cell cryopreservation Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: AMPAW, Anna
Graduate Fellowship Program $52,000
Management of iron deficiency anemia in the pediatric emergency department: Pilot study of red blood cell transfusion versus IV iron therapy Principal Investigator: LIEBMAN, Mira

Co-Investigator(s) / Trainee: PAMBRUN, Chantale JAIN, Rini SIMPSON, Ewurabena HAMID, Jemila
Blood Efficiency Accelerator Award Program $30,000
Platelet desialylation: novel mechanism of platelet clearance and immune tolerance Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: LI, June
Graduate Fellowship Program $104,000
A program to minimize preventable and inappropriate blood product transfusions in liver surgery Principal Investigator: MARTEL, Guillaume

Co-Investigator(s) / Trainee: BAKER, Laura, TINMOUTH, Alan, SAIDENBERG, Elianna, WHERRETT, Christopher, WORKNEH, Aklile
Blood Efficiency Accelerator Award Program $20,000
Blood utilization epidemiological profile to evaluate appropriate use (BLUE) Principal Investigator: ZELLER, Michelle

Co-Investigator(s) / Trainee: ARNOLD, Donald WEBERT, Kathryn HEDDLE, Nancy NING, Shuoyan BARTY, Rebecca
Blood Efficiency Accelerator Award Program $29,964
Blood product demand forecast modeling using clinical predictors Principal Investigator: DOWN, Douglas

Co-Investigator(s) / Trainee: BLAKE, John , TRIFUNOV, Rick COURTNEY, Thomas HEDDLE, Nancy CHIANG, Fei LI, Na
Blood Efficiency Accelerator Award Program $30,000
Evaluation and improvement of cold stored platelets Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: ZHAO, Hanqi (Wayne)
Graduate Fellowship Program $52,000
Development of a small molecule-based stem and progenitor expansion protocol to accelerate engraftment after cord blood transplantation Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MANESIA, Javed
Postdoctoral Fellowship Program $101,200
Optimizing rejuvenation to improve the product quality of pathogen-inactivation and γ-irradiated red cell concentrates Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: QADRI, Syed, SCHUBERT, Peter, DEVINE, Dana
Blood Efficiency Accelerator Award Program $30,000
Transfusion-Related Acute Lung Injury and delayed TRALI: a prospective study in critically ill children Principal Investigator: EMERIAUD, Guillaume

Co-Investigator(s) / Trainee: Du PONT-THIBIDEAU, Genevieve, FONTELA, Patricia S. , GAUVIN, France, GILFOYLE, Elaine, HUTCHISON, James S., LACROIX, Jacques, MENON, Kusum, ROBITAILLE, Nancy, TINMOUTH, Alan T., TROTTIER, Helen
Canadian Blood Services-CIHR Partnership Operating Grant Program $477,651
Code sepsis: defining and translating optimal resuscitation and care for children with septic shock Principal Investigator: PARKER, Melissa

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership New Investigator Program $300,000
Canadian cord blood banking: Legal and Policy Responses Principal Investigator: CAULFIELD, Timothy

Co-Investigator(s) / Trainee: MURDOCH, Blake MARCON, Alessandro
James Kreppner Award Program $50,000
A multifaceted intervention to optimize red blood cell transfusion practice in two provinces Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee: NAHIRNIAK, Susan, CALLUM, Jeannie, LIN, Yulia, ZELLER, Michelle
Intramural Research Grant Program $332,942
Assessment of the quality of granulocyte concentrates to optimise their use in transfusion therapy Principal Investigator: FERNANDES, Maria

Co-Investigator(s) / Trainee: GIRARD, Mélissa, BRANCH, Donald
Blood Efficiency Accelerator Award Program $30,000
Plasma versus plasma protein concentrate transfusion for coagulopathic control Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program $224,417