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Our Funded Research Projects

Updated January 2020

Title Principal Investigator / Supervisor Program Project Start Date Project End Date Sort ascending Total $ Awarded
Deformability based cell sorting enabling quality control of stored red blood cells Principal Investigator: MA, Hongshen

Co-Investigator(s) / Trainee: ISLAMZADA, EMEL
Graduate Fellowship Program 52000
Replacement of intravenous immunoglobulin for treatment of immune cytopenias Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: ALMIZRAQ, Ruqayyah
Postdoctoral Fellowship Program 150000
Reducing IVIG usage by developing novel prophylaxis therapies against FNAIT Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: PASMAN, Yfke
Postdoctoral Fellowship Program 150000
Donor characteristics and the quality of red cell concentrates Principal Investigator: ACKER, Jason P

Co-Investigator(s) / Trainee: MYKHAILOVA, Olga
Postdoctoral Fellowship Program 150000
Modulating of biofilm formation, virulence, and antimicrobial resistance by Staphylococcus aureus during platelet storage Principal Investigator: RAMIREZ-ARCOS, Sandra

Co-Investigator(s) / Trainee: SAD, Subash, MAH, Thien-Fah
Intramural Research Grant Program 299308
IN-TRUST: Using a transfusion databse to explore the immune-modulatory impacts of blood transfusion and the clinical impacts of blood processing changes Principal Investigator: NING, Shuoyan

Co-Investigator(s) / Trainee: ARNOLD, Donald, ZELLER, Michelle, ACKER, Jason, LI, Na, HEDDLE, Nancy, HILLIS, Christopher, ROCHWERG, Bram, SYED, Summer
Intramural Research Grant Program 250326
Anti-GPIb mediated thrombocytopenia: implications for IVIG and other therapies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: LAZARUS, Alan, BRANCH, Donald
Intramural Research Grant Program 381491
Small molecule drug development of phagocytosis inhibitors Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: KOTRA, Lakshmi, P.
Intramural Research Grant Program 396730
Fc receptors and IVIg in ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: CSERTI-GAZDEICH, Christine, LIN, Yulia, CALLUM, Jeannie, SHOLZBERG, Michelle, NI, Heyu
Intramural Research Grant Program 400000
Novel detection strategies for new platelet ligands and anti-platelet antibodies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: NEVES, Miguel
Postdoctoral Fellowship Program 150000
Plasma transfusion or plasma protein product infusion in a murine model of trauma Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: PRYZDIAL, Edward
Intramural Research Grant Program 238347
Synthesis of carbohydrate derivatives for the improvement of red blood cell storage Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: MEYER, Julia
Graduate Fellowship Program 82000
Novel cell-surface engineering methods to increase immune-tolerance of allogenic cell transplantation Principal Investigator: KIZHAKKEDATHU, Jayachandran

Co-Investigator(s) / Trainee: MOON, Haisle
Graduate Fellowship Program 82000
A novel clot-dissolving agent derived from clotting factor Va Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: LEE, Frank
Graduate Fellowship Program 52000
New solution for cord blood Unit preservation Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: KAUSHAL, Richa
Graduate Fellowship Program 52000
Monovalent Fc receptor blockade using novel fusion proteins: The road towards an IVIg replacement Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: SHEFFIELD, William, BRANCH, Donald
Intramural Research Grant Program 400000
Monoclonal antibodies with anti-D like activity in amelioration of murine ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: KHAN, RAMSHA
Graduate Fellowship Program 52000
Investigating the mechanism of anti-CD44 antibody amelioration of IVIg-treatable disease Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NORRIS, Peter
Graduate Fellowship Program 104000
Influence of eryptosis and storage on transfused red cell recovery in sepsis Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: BRANCH, Donald, LIAW, Patricia, HEDDLE, Nancy, QADRI, Syed
Intramural Research Grant Program 283569
Optimizing rejuvenation to improve the product quality of pathogen-inactivation and γ-irradiated red cell concentrates Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: QADRI, Syed, SCHUBERT, Peter, DEVINE, Dana
Blood Efficiency Accelerator Award Program 30000
Allowing MSM to donate in the context of pathogen reduction of blood components: mathematical modeling of the risk of HIV, HBV and HCV transmission through transfusion Principal Investigator: LEWIN, Antoine

Co-Investigator(s) / Trainee: GERMAIN, Marc, DELAGE, Gilles, ROBILLARD, Pierre, GRÉGOIRE, Yves, WILLIAM, Fraser
MSM Research Grant Program 29618
A study to understand C1 Esterase Inhibitor distribution and patterns of use in Canada Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: HEDDLE, Nancy, KEITH, Paul, WASERMAN, SUSAN, WEBERT, Kathryn, NING, Shuoyan
Blood Efficiency Accelerator Award Program 29858.62
Mathematical Modelling – Comparing HIV Risk Between MSM Donation Strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GERMAIN, Marc, GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program 24000
Évaluation de l’acceptabilité et de la faisabilité d’un programme de dons de plasma destiné au fractionnement, pour les hommes ayant des relations sexuelles avec d’autres hommes de la communauté gaie montréalaise Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, GODIN, Gaston, PRONOVOST, Frédérick, MONTEITH, Kenneth, MYHAL, Geneviève, GIRARD, Gabriel, MORIN, Michel
MSM Research Grant Program 219507
Measurement of Heavy Metals in Donor Blood in Canada Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: SERRANO, Katherine, LEVIN, Elena, MURPHY, Michael, BARAKAUSKAS, Vilte, HADJESFAMDOARI, Narges, ARRIETA, Angele, RICHARDSON-SANCHEZ, Tomas
Blood Efficiency Accelerator Award Program 29971
Understanding general population impact and opportunities from changes to blood donation deferral screening and criteria for men who have sex with men Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: BRENNAN, David, CARD, Kiffer, DRYDEN, OmiSoore, GASPAR, Mark, GILBERT, Mark, GRACE, Daniel, KNIGHT, Rodney, LEBOUCHÉ, Bertrand, MORGAN, Jeffrey, SALWAY, Travis
MSM Research Grant Program 300000
Are cervical cancer bracytherapy outcomes associated with pre-braccytherapy hemoglobin values and transfusion practice? An observational study comparing two academic centres. Principal Investigator: SOLH, Ziad

Co-Investigator(s) / Trainee: LAZO-LANGER, Alejandro, D'SOUZA, David, CALLUM, Jeannie, LEUNG, Eric, CHIN-YEE, Ian
Blood Efficiency Accelerator Award Program 27669.5
Feasibility of implementing source plasma donation with alternative eligibility criteria for men who have sex with men Principal Investigator: PRESSEAU, Justin

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, GERMAIN, Marc, DEVINE, Dana, ROSSER, Andrew, LAPIERRE, Don
MSM Research Grant Program 299950
Optimization of monoclonal anti-erythrocyte antibodies for improved immunoprophylaxis in a murine model Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program 400000
Estimating the probability of HIV risk in MSM donor policies through biobehavioural and mathematical modelling studies Principal Investigator: HART, Trevor

Co-Investigator(s) / Trainee: LAMBERT, Gilles, GRACE, Daniel, BAUER, Greta, MOORE, David, COX, Joseph, LACHOWSKY, Nathan, MISHRA, Sharmistha, BRENNAN, David, TAN, Darrell
MSM Research Grant Program 442500
Development of a small molecule cocktail for the expansion of cord blood stem cells Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: BLAKE, John, AUDET, Julie
Intramural Research Grant Program 220000
Evaluating the role of donor characteristics and blood component manufacturing on the quality of red cell concentrates Principal Investigator: ACKER, Jason P

Co-Investigator(s) / Trainee: BRANCH, Donald, CLARKE, Gwen, NAHIRNIAK, Susan
Intramural Research Grant Program 368873
TAD-POL (Transfusion-Associated-Dyspnea: Prospective observation and laboratory assessment) Principal Investigator: CSERTI-GAZDEWICH, Christine

Co-Investigator(s) / Trainee: BRANCH, Donald, LAZARUS, Alan, CALLUM, Jeannie, LIN, Yulia, PENDERGRAST, Jacob, LIEBERMAN, Lani, SHEHATA, Nadine, PAVENSKI, Katerina, SKEATE, Robert
Intramural Research Grant Program 278027.45
The mechanism of action of monoclonal antibody blends in the potential replacement of anti-D in HDFN Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: CRUZ-LEAL, Yoelys
Postdoctoral Fellowship Program 150000
Sex Now 2018: A national survey on blood donation and undiagnosed blood borne infections Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: TRUSSLER, Terry, GILBERT, Mark, SALWAY, Travis, JOLLIMORE, Jody, HAM, David, LOFTUS, Patrick, OLIVER, Brent, HANSEN, Brian, VISSER, Floyd, BRENNAN, David, GRACE, Daniel, OTIS, Joanne, LEBOUCHÉ, Bertrand, NUMER, Matthew, SAXTON, Peter
MSM Research Grant Program 411719
Of skin, sperm, and blood: A comparative analysis of exemptions in Canadian human tissue legislation Principal Investigator: CATTAPAN, Alana

Co-Investigator(s) / Trainee: VON TIGERSTROM, Barbara, NELSON, Eric, DAWSON, Roseanne
James Kreppner Award Program 43275
McMaster Centre for Transfusion Research Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee:
Transfusion Medicine Research Program Support Award 1150000
ACB and MSM - it's not an oxymoron: A research project that explores the importance of ACB people in MSM blood donation research Principal Investigator: DRYDEN, OmiSoore

Co-Investigator(s) / Trainee: LEE, Woo Jin Edward, NELSON, LaRon, MARSHALL, Zack, MBUAGBAW, Lawrence
MSM Research Grant Program 400000
University of Toronto QUEST Research Program Principal Investigator: CALLUM, Jeannie

Co-Investigator(s) / Trainee:
Transfusion Medicine Research Program Support Award 1137400
Canadians’ Attitudes and Opinions Regarding Cardiac Donation after Cardiocirculatory Death: A mixed-methods study Principal Investigator: BALL, Ian

Co-Investigator(s) / Trainee: WEISS, Matt D'ARAGON, Fred PARSONS LEIGH, Jenna HONARMAND, Kimia BASMAJI, John SIBBALD, Robert
Kenneth J. Fyke Award Program 95929
Expanding treatment options for inflammatory bowel disease: a novel mechanism of antibody-based immunotherapy Principal Investigator: SLY, Laura

Co-Investigator(s) / Trainee: HORWITZ, Marc, BRESSLER, Brian, RASSEKH, Rod, TURVEY, Stuart
Canadian Blood Services-CIHR Partnership Operating Grant Program 387855
Fetal and neonatal alloimmune thrombocytopenia: novel mechanisms and therapeutic approaches Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 447525
Applying educational tools of knowledge translation to reduce the inappropriate use of plasma in Ontario: a collaboration between Canadian Blood Services and Ontario hospitals Principal Investigator: SOLH, Ziad

Co-Investigator(s) / Trainee: SKEATE, Robert, BERTA, Donna, CALLUM, Jeannie, LIMA, Ana, ZELLER, Michelle, ELAHIE, Allahna, HEDDLE, Nancy, THOMPSON, Troy, TINMOUTH, Alan, SHEHATA, Nadine, ILAGAN, Cesario
BloodTechNet Award Program 7200
Novel mechanisms of platelet aggregation: Roles of non-classical beta-3 integrin ligands and fibronectin in thrombosis and hemostasis Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee:
Canadian Blood Services-CIHR Partnership Operating Grant Program 378675
Virtual transfusions competency assessment Principal Investigator: VAN VLIET, Paula

Co-Investigator(s) / Trainee: DEYDEY, Kim WESOLOWSKI, Mike
BloodTechNet Award Program 32795
Development of internet modules for serology curriculum delivery Principal Investigator: YAN, Matthew

Co-Investigator(s) / Trainee: PENDERGRAST, Jacob, TAIT, Gordon
BloodTechNet Award Program 35500
Blood product demand forecast modeling using clinical predictors Principal Investigator: DOWN, Douglas

Co-Investigator(s) / Trainee: BLAKE, John , TRIFUNOV, Rick, COURTNEY, Thomas, HEDDLE, Nancy, CHIANG, Fei, LI, Na
Blood Efficiency Accelerator Award Program 30000
Evaluation and improvement of cold stored platelets Principal Investigator: DEVINE, Dana

Co-Investigator(s) / Trainee: ZHAO, Hanqi (Wayne)
Graduate Fellowship Program 52000
Rapid verification variant D phenotype by genotyping in a regional laboratory Principal Investigator: BERARDI, Philip

Co-Investigator(s) / Trainee: FUNG KEE FUNG, Karen, GIULIVI, Antonio, NEURATH, Doris, CLARKE, Gwen
Blood Efficiency Accelerator Award Program 30000
Investigating a new class of small molecule ice recrystallization inhibitors for red blood cell cryopreservation Principal Investigator: BEN, Robert

Co-Investigator(s) / Trainee: AMPAW, Anna
Graduate Fellowship Program 52000