RBC Genotyping Testing for RHCE and Extended Blood Groups

Test description

These are PCR-based assays for the identification of multiple alleles encoding human erythrocyte antigens in genomic DNA. The RHCE test identifies many clinically significant variants responsible for normal and altered expressions of the RHCE human red cell antigens. Testing for allelic variants in the following extended blood groups can determine the patient’s predicted expression of the antigens: Rh, Kell, Duffy, Kidd, MNS, Lutheran, Dombrock, Landsteiner-Wiener, Diego, Colton and Scianna. These tests are alternatives to serological testing in cases of discordant antigen phenotyping results, autoimmune hemolytic anemia, chronically transfused patients with previously identified antibodies, and patients with transfusion dependent diseases such as sickle cell disease and thalassemia.

RBC Genotype Testing for RHCE and Extended Blood Groups (PDF)

Test Catalogue

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Specimen and requisition requirements

Specimen(s):

Minimum of one (1) 2-6 ml EDTA (lavender) tubes, mixed thoroughly by gentle agitation.

Label specimen with the required minimum information: patient’s last name, first name, PHN or Unique Lifetime Identifier (ULI) and date of collection.

Complete Requisition (must include):

  • Patient’s last name, first name, date of birth and PHN or ULI
  • Facility name, complete address, phone and fax number
  • Phlebotomist ID information
  • Date of collection

Requisition(s)​

Requisition for Blood Group Genotyping - Patient (NIRL) (PDF)
Demande de génotypage sanguin (patient) (NIRL) (PDF) 

Pre-shipping storage

Recommended Refrigeration 1-10°C

Shipping instructions

Submit samples as soon as possible after collection.

Shipping

Ship in a container that will maintain temperature at ≥1°C.

Select shipping method for container to arrive at testing site within 48 hours.

Sample must arrive at testing site within 14 days of sample collection

Note: Protect from freezing.

Send to

Canadian Blood Services
Edmonton Centre
8249 114 St NW
Edmonton, AB  T6G 2R8
Attention:  Diagnostic Services Laboratory

Tel: 780-431-8765
Fax: 780-431-8747