Our Research Publications

Updated August 2024

Title Authors Year Journal Link to Article Intended Audience Purpose
ResearchUnit: Red cell irradiation - time for a change? Serrano K 2014 Blood.ca website View Other Other
TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage Prudova A, Serrano K, Eckhard U, Fortelny N, Devine DV, Overall CM 2014 Blood View Researchers Basic research
The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice Eltringham-Smith LJ, Lei X, Reheman A, Lambourne MD, Pryzdial EL, Ni H, Sheffield WP 2014 Transfusion View Researchers Basic research
The size-dependent efficacy and biocompatibility of hyperbranched polyglycerol in peritoneal dialysis Du C, Mendelson AA, Guan Q, Chapanian R, Chafeeva I, da Roza G, Kizhakkedathu JN 2014 Biomaterials View Researchers Basic research
A method to measure permeability of red blood cell membrane to water and solutes using intrinsic fluorescence Zhurova M, Olivieri A, Holt A, Acker JP 2014 Clin Chim Acta View Researchers Basic research
Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 Artif Cells Nanomed Biotechnol View Researchers Basic research
Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers Wang A, Kluger R 2014 Biochemistry View Researchers Basic research
Opinion: 'Family veto' dilemma and organ donation Toews M, Caulfield T 2014 Edmonton Journal View Other Other
Phenotype matching for sickle cell patients: a review and recommendations for transfusion practice Skeate R, Goldman M 2014 Blood.ca website View Health care providers Other
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium Jimenez-Diaz MB, Ebert D, Salinas Y, Pradhan A, Lehane AM, Myrand-Lapierre ME, O'Loughlin KG, Shackleford DM, Justino de Almeida M, Carrillo AK, Clark JA, Dennis AS, Diep J, Deng X, Duffy S, Endsley AN, Fedewa G, Guiguemde WA, Gomez MG, Holbrook G, Horst J, Kim CC, Liu J, Lee MC, Matheny A, Martinez MS, Miller G, Rodriguez-Alejandre A, Sanz L, Sigal M, Spillman NJ, Stein PD, Wang Z, Zhu F, Waterson D, Knapp S, Shelat A, Avery VM, Fidock DA, Gamo FJ, Charman SA, Mirsalis JC, Ma H, Ferrer S, Kirk K, Angulo-Barturen I, Kyle DE, DeRisi JL, Floyd DM, Guy RK 2014 PNAS View Researchers Basic research
A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models Sheffield WP, Eltringham-Smith LJ, Gataiance S, Bhakta V 2014 J Thromb Thrombolysis View Researchers Basic research
Cytokine profiles in mouse models of experimental immune thrombocytopenia reveal a lack of inflammation and differences in response to intravenous immunoglobulin depending on the mouse strain Leontyev D, Neschadim A, Branch DR 2014 Transfusion View Researchers Basic research
Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis Chasse M, English S, McIntyre L, Knoll G, Shehata N, Forster A, Wilson K, van Walraven C, Tinmouth A, Fergusson D 2014 Syst Rev View Researchers Clinical research
How safe is safe enough, who decides and how? From a zero-risk paradigm to risk-based decision making Menitove JE, Leach Bennett J, Tomasulo P, Katz LM 2014 Transfusion View Blood operators Other
The effects of rejuvenation during hypothermic storage on red blood cell membrane remodeling Kurach JDR, Almizraq R, Bicalho B, Acker JP, Holovati JL 2014 Transfusion View Researchers Basic research
Antibody-Mediated Immune Suppression of Erythrocyte Alloimmunization Can Occur Independently from Red Cell Clearance or Epitope Masking in a Murine Model Yu H, Stowell SR, Bernardo L, Hendrickson JE, Zimring JC, Amash A, Uchikawa M, Lazarus AH 2014 J Immunol View Researchers Basic research
Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol Lalu MM, Moher D, Marshall J, Fergusson D, Mei SH, Macleod M, Griffin G, Turgeon AF, Rudnicki M, Fishman J, Avey MT, Skidmore B, Grimshaw JM, Stewart DJ, Singh K, McIntyre L 2014 Syst Rev View Researchers Clinical research
gT-S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo Sheffield WP, Lambourne MD, Eltringham-Smith LJ, Bhakta V, Arnold DM, Crowther MA 2014 J Thromb Haemost View Researchers Basic research
Low pertussis toxin antibody levels in two regional cohorts of Canadian pregnant women Bigham M, Konrad S, Van Buynder P, Van Buynder J, Isaac-Renton J, ElSherif M, Halperin SA 2014 Vaccine View Health care providers Clinical research
Pathogenesis of immune thrombocytopenia Cines DB, Cuker A, Semple JW 2014 Presse Med View Researchers Clinical research
Research opportunities in optimizing storage of red blood cell products Wagner SJ, Glynn SA, Welniak LA, NHLBI Working Group on Strategies to Optimize Red Blood Cell Products 2014 Transfusion View Researchers Other
ResearchUnit: Research into TRALI therapies gene therapy results that are a TAD interesting! Semple J 2014 Blood.ca website View Other Other
Risk of serious gastrointestinal bleeding in living kidney donors Thomas SM, Lam NN, Huang A, Nash DM, Prasad GV, Knoll GA, Koval JJ, Lentine KL, Kim SJ, Alam A, Lok CE, Treleaven DJ, Garg AX 2014 Clin Transplant View Health care providers Clinical research
Are donors in Canada compliant with deferral for tattoos and piercing? O'Brien S F, Xi G, Fan W, Yi Q, Osmond L, Delage G, Goldman M 2014 Blood Transfus View Blood operators New or improved product or process
Engineering biomaterials surfaces to modulate the host response Yu K, Mei Y, Hadjesfandiari N, Kizhakkedathu JN 2014 Colloids Surf B Biointerfaces View Researchers Basic research
IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist von Gunten S, Shoenfeld Y, Blank M, Branch DR, Vassilev T, Kasermann F, Bayry J, Kaveri S, Simon HU 2014 Nat Rev Immunol View Researchers Other
A platelet cover-up Arnold DM 2013 Blood View Researchers Other
Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition Roddick LA, Bhakta V, Sheffield W 2013 BMC Biochem View Researchers Basic research
Legal Aspects of the Blood System in Canada Reis NM 2013 Public Health Law and Policy in Canada View Other Other
Positioning new treatments in the management of immune thrombocytopenia Arnold DM 2013 Pediatr Blood Cancer View Researchers Clinical research
Alloimmunization of patients by blood units harboring distinct DEL variants St-Louis M, Lebrun A, Goldman M, Lavoie M 2013 Immunohematology View Health care providers Clinical research
Research with Blood Donated to Blood Banking Organizations Reis NM 2013 Health Law Review View Other Other
Utility of cross-matched platelet transfusions in patients with hypoproliferative thrombocytopenia: a systematic review Vassallo RR, Fung M, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation Evaluation for Transfusion Therapies Collaborators 2013 Transfusion View Researchers Clinical research
CD4+ T-cells are unable to express the HIV natural resistance factor globotriosylceramide Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR 2013 AIDS View Researchers Basic research
Developing highly active small molecule ice recrystallization inhibitors based upon C-linked antifreeze glycoprotein analogues Trant JF, Briggs RA, Capicciotti C, Ben RN 2013 RSC Adv View Researchers Basic research
Phospholipidomics reveals differences in glycerophosphoserine profiles of hypothermically stored red blood cells and microvesicles Bicalho B, Holovati JL, Acker JP 2013 Biochim Biophys Acta View Researchers Basic research
The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand Boyle AJ, Roddick LA, Bhakta V, Lambourne MD, Junop MS, Liaw PC, Weitz JI, Sheffield WP 2013 BMC Biochem View Researchers Basic research
Legal Foundations of Public Health Law Reis NM 2013 Public Health Law and Policy in Canada View Other Other
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV 2013 Transfusion View Researchers Basic research
Allowing blood donation from men who had sex with men more than 5 years ago: a model to evaluate the impact on transfusion safety in Canada Germain M, Robillard P, Delage G, Goldman M 2013 Vox Sang View Blood operators New or improved product or process
Design of long circulating nontoxic dendritic polymers for the removal of iron in vivo Imran ul-haq M, Hamilton JL, Lai BF, Shenoi RA, Horte S, Constantinescu I, Leitch HA, Kizhakkedathu JN 2013 ACS Nano View Researchers Basic research
Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review Pavenski K, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation and Evaluation for Transfusion Therapies (ICTMG) Collaborators 2013 Transfusion View Researchers Clinical research
Fc-independent phagocytosis: Implications for IVIG and other therapies in immune-mediated thrombocytopenia Li J, van der Wal DE, Zhu L, Vadasz B, Simpson EK, Li C, Webster ML, Zhu G, Lang S, Chen P, Zeng Q, Ni H 2013 Cardiovasc Hematol Disord Drug Targets View Researchers Other
Identifying D-positive donors using a second automated testing platform Goldman M, Resz I, Cote J, Ochoa G, Angus N 2013 Immunohematology View Blood operators New or improved product or process
ResearchUnit: Should patients receive HLA-selected platelets? Shehata N 2013 Blood.ca website View Other Other
Utilization of frozen plasma in Ontario: a province wide audit reveals a high rate of inappropriate transfusions Tinmouth A, Thompson T, Arnold DM, Callum JL, Gagliardi K, Lauzon D, Owens W, Pinkerton P 2013 Transfusion View Health care providers Benchmarking and standard setting
An enclosed in-gel PCR amplification cassette with multi-target, multi-sample detection for platform molecular diagnostics Manage DP, Lauzon J, Atrazev A, Chavali R, Samuel RA, Chan B, Morrissey YC, Gordy W, Edwards AL, Larison K, Yanow SK, Acker JP, Zahariadis G, Pilarski LM 2013 Lab Chip View Health care providers New or improved product or process
CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis Mott PJ, Lazarus AH 2013 PLoS One View Researchers Basic research
Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain Kurbegovic A, Trudel M 2013 Hum Mol Genet View Researchers Basic research
ResearchUnit: Doubling the 30-minute rule without compromising Red Blood Cells quality and safety. Ramirez-Arcos S 2013 Blood.ca website View Other Other