Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Noninvasive pH monitoring for bacterial detection in platelet concentrates Loza-Correa M, Perkins H, Kumaran D, Kou Y, Qaisar R, Geelhood S, Ramirez-Arcos S 2016 Transfusion View Researchers New or improved product or process
Pathogenesis of immune thrombocytopenia Cines DB, Cuker A, Semple JW 2014 Presse Med View Researchers Clinical research
Platelet microparticles reprogram macrophage gene expression and function Laffont B, Corduan A, Rousseau M, Duchez AC, Lee CH, Boilard E, Provost P 2016 Thromb Haemost View Researchers Basic research
Quality of red blood cells washed using the ACP 215 cell processor: assessment of optimal pre- and postwash storage times and conditions Hansen A, Yi QL, Acker JP 2013 Transfusion View Researchers New or improved product or process
Research opportunities in optimizing storage of red blood cell products Wagner SJ, Glynn SA, Welniak LA, NHLBI Working Group on Strategies to Optimize Red Blood Cell Products 2014 Transfusion View Researchers Other
Splenic lymphocyte subtypes in immune thrombocytopenia: increased presence of a subtype of B-regulatory cells Aslam R, Segel GB, Burack R, Spence SA, Speck ER, Guo L, Semple JW 2016 Br J Haematol View Researchers Basic research
The Grand Challenges of Organ Banking: Proceedings from the first global summit on complex tissue cryopreservation Lewis JK, Bischof JC, Braslavsky I, Brockbank KGM, Fahy GM, Fuller BJ, Rabin Y, Tocchio A, Woods EJ, Wowk BG, Acker JP, Giwa S 2016 Cryobiology View Researchers Other
The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia Aslam R, Kapur R, Segel GB, Guo L, Zufferey A, Ni H, Semple JW 2016 Exp Hematol View Researchers Basic research
Genomic data in prognostic models-what is lost in translation? The case of deletion 17p and mutant TP53 in chronic lymphocytic leukaemia Chin-Yee B, Sadikovic B, Chin-Yee I 2019 Br J Haematol View Researchers Clinical research
Red blood cells, still vital after all these years: Commentary on Canadian Blood Services' International Symposium 2017 Qadri SM, Donkor DA, Yan M, Ning S, Branch DR, Seghatchian J, Sheffield WP 2018 Transfus Apher Sci View Researchers Other
Megakaryocyte apoptosis in immune thrombocytopenia Vrbensky JR, Nazy I, Toltl LJ, Ross C, Ivetic N, Smith JW, Kelton JG, Arnold DM 2018 Platelets View Researchers Basic research
The association between influenza vaccination and socioeconomic status in high income countries varies by the measure used: a systematic review Lucyk K, Simmonds KA, Lorenzetti DL, Drews SJ, Svenson LW, Russell ML 2019 BMC Med Red Methodol View Researchers Clinical research
Development and evaluation of a generic population pharmacokinetic model for standard half-life factor VIII for use in dose individualization McEneny-King A, Chelle P, Foster G, Keepanasseril A, Iorio A, Edginton AN 2019 J Pharmacokinet Pharmacodyn View Researchers Clinical research
The Impact of Bacterial Biofilms in Transfusion Medicine Ramirez-Arcos S 2020 Racing for the Surface View Researchers Basic research
Optimizing the supply of whole blood-derived bioproducts through the combined implementation of cryopreservation and pathogen reduction technologies and practices: An overview Bohonek M, Kutac D, Acker JP, Seghatchian J 2020 Transfus Apher Sci View Researchers New or improved product or process
Sex-mismatched red blood cell transfusions and mortality: A systematic review and meta-analysis Zeller MP, Rochwerg B, Jamula E, Li N, Hillis C, Acker JP, Runciman RJR, Lane SJ, Ahmed N, Arnold DM, Heddle NM 2019 Vox Sang View Researchers Clinical research
Cardiac donation after circulatory determination of death: protocol for a mixed-methods study of healthcare provider and public perceptions in Canada Honarmand K, Ball I, Weiss M, Slessarev M, Sibbald R, Sarti A, Meade M, D'Aragon F, Chasse M, Basmaji J, Parsons Leigh J 2020 BMJ Open View Researchers New or improved product or process
Control of ice recrystallization in liver tissues using small molecule carbohydrate derivatives William N, Acker JP 2020 Cryobiology View Researchers Basic research
Opportunities for standardization of cold stored, low-titre group O WB products Acker JP, Seghatchian J 2020 Transfus Apher Sci View Researchers New or improved product or process
ResearchUnit: Donating blood before pregnancy is safe for mothers and babies Chassé M 2020 Blood.ca website View Researchers Clinical research
Spontaneous HIT syndrome: Knee replacement, infection, and parallels with vaccine-induced immune thrombotic thrombocytopenia Warkentin TE, Greinacher A 2021 Thromb Res View Researchers Clinical research
Blood bank storage of red blood cells increases RBC cytoplasmic membrane order and bending rigidity Himbert S, Qadri SM, Sheffield WP, Schubert P, D’Alessandro A, Rheinstädter MC 2021 PLoS One View Researchers Basic research
Spotlight on animal models of acute traumatic coagulopathy: An update Ask A, Eltringham-Smith L, Bhakta V, Donkor DA, Pryzdial ELG, Sheffield WP 2022 Transfus Apher Sci View Researchers Basic research
A naturally present autoantibody to senescent red blood cells? Badior KE, Bloch EM, Branch DR 2022 Transfusion View Researchers Benchmarking and standard setting
Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency Dahal S, Clayton K, Been T, Fernet-Brochu R, Ocando AV, Balachandran A, Poirier M, Maldonado RK, Shkreta L, Boligan KF, Guvenc F, Rahman F, Branch D, Bell B, Chabot B, Gray-Owen SD, Parent LJ, Cochrane A 2022 Retrovirology View Researchers Basic research
A data-driven approach to determine daily platelet order quantities at hospitals Mirjalili M, Abouee-Mehrizi H, Barty R, Heddle NM, Sarhangian V 2022 Transfusion View Researchers New or improved product or process
Unique features of vaccine-induced immune thrombotic thrombocytopenia; a new anti-platelet factor 4 antibody-mediated disorder Venier LM, Clerici B, Bissola AL, Modi D, Jevtic SD, Radford M, Mahamad S, Nazy I, Arnold DM 2023 Int J Hematol View Researchers Clinical research
A method to measure permeability of red blood cell membrane to water and solutes using intrinsic fluorescence Zhurova M, Olivieri A, Holt A, Acker JP 2014 Clin Chim Acta View Researchers Basic research
Acquired Factor XIII Inhibitor in Hospitalized and Perioperative Patients: A Systematic Review of Case Reports and Case Series Tone KJ, James TE, Fergusson DA, Tinmouth A, Tay J, Avey MT, Kilty S, Lalu MM 2016 Transfus Med Rev View Researchers Clinical research
Amelioration of murine immune thrombocytopenia by CD44 antibodies: a potential therapy for ITP? Crow AR, Song S, Suppa SJ, Ma S, Reilly MP, Andre P, McKenzie SE, Lazarus AH 2011 Blood View Researchers Basic research
Comparative characterisation of the biofilm-production abilities of Staphylococcus epidermidis isolated from human skin and platelet concentrates Taha M, Kohnen C, Mallya S, Kou Y, Zapata A, Ramirez-Arcos S 2018 J Med Microbiol View Researchers New or improved product or process
Cytokine profiles in mouse models of experimental immune thrombocytopenia reveal a lack of inflammation and differences in response to intravenous immunoglobulin depending on the mouse strain Leontyev D, Neschadim A, Branch DR 2014 Transfusion View Researchers Basic research
Dicer1 mediated miRNA processing shapes the mRNA profile and function of murine platelets Rowley JW, Chappaz S, Corduan A, Chong MM, Campbell R, Khoury A, Manne BK, Wurtzel JG, Michael JV, Goldfinger LE, Mumaw MM, Nieman MT, Kile BT, Provost P, Weyrich AS 2016 Blood View Researchers Basic research
Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis Chasse M, English S, McIntyre L, Knoll G, Shehata N, Forster A, Wilson K, van Walraven C, Tinmouth A, Fergusson D 2014 Syst Rev View Researchers Clinical research
Extracellular histones identified in crocodile blood inhibit in-vitro HIV-1 infection Kozlowski HN, Lai ET, Havugimana PC, White C, Emili A, Sakac D, Binnington B, Neschadim A, McCarthy SD, Branch DR 2016 AIDS View Researchers Basic research
Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition Roddick LA, Bhakta V, Sheffield W 2013 BMC Biochem View Researchers Basic research
Mesenchymal stromal cells derived from umbilical cord blood migrate in response to complement C1q Qiu Y, Marquez-Curtis LA, Janowska-Wieczorek A 2012 Cytotherapy View Researchers Basic research
Moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is required for efficient hepatitis C virus and dengue virus infections in human Huh-7.5.1 cells Raj M, Langley M, McArthur SJ, Jean F 2017 J Gen Virol View Researchers Basic research
Optimal Attenuation of Experimental Autoimmune Encephalomyelitis by Intravenous Immunoglobulin Requires an Intact Interleukin-11 Receptor Figueiredo CA, Drohomyrecky PC, McCarthy SDS, Leontyev D, Ma X-Z, Branch DR, Dunn SE 2014 PLoS One View Researchers Basic research
Phosphatidylserine externalization and procoagulant activation of erythrocytes induced by Pseudomonas aeruginosa virulence factor pyocyanin Qadri SM, Donkor DA, Bhakta V, Eltringham-Smith LJ, Dwivedi DJ, Moore JC, Pepler L, Ivetic N, Nazi I, Fox-Robichaud AE, Liaw PC, Sheffield WP 2016 J Cell Mol Med View Researchers Basic research
Platelets and platelet alloantigens: lessons from human patients and animal models of fetal and neonatal alloimmune thrombocytopenia Vadasz B, Chen P, Yougbare I, Zdravic D, Li J, Li C, Carrim N, Ni H 2015 Genes Dis View Researchers Other
Producing megakaryocytes from a human peripheral blood source Ivetic N, Nazi I, Karim N, Clare R, Smith JW, Moore JC, Hope KJ, Kelton JG, Arnold DM 2016 Transfusion View Researchers Basic research
Red blood cell membrane grafting of multi-functional hyperbranched polyglycerols Rossi NAA, Constantinescu I, Kainthan RK, Brooks DE, Scott MD, Kizhakkedathu JN 2010 Biomaterials View Researchers Basic research
Structure-activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias Purohit MK, Chakka SK, Scovell I, Neschadim A, Bello AM, Salum N, Katsman Y, Bareau MC, Branch DR, Kotra LP 2014 Bioorg Med Chem View Researchers Basic research
The clinical significance of platelet microparticle-associated microRNAs Provost P 2017 Clin Chem Lab Med View Researchers Basic research
The maternal immune response to fetal platelet GPIb? causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies Li C, Piran S, Chen P, Lang S, Zarpellon A, Jin JW, Zhu G, Reheman A, van der Wal DE, Simpson EK, Ni R, Gross PL, Ware J, Ruggeri ZM, Freedman J, Ni H 2011 J Clin Invest View Researchers Basic research
Thrombin a-chain: activation remnant or allosteric effector? Carter IS, Vanden Hoek AL, Pryzdial EL, Macgillivray RT 2010 Thrombosis View Researchers Basic research
Virtual screen for repurposing approved and experimental drugs for candidate inhibitors of EBOLA virus infection Veljkovic V, Loiseau PM, Figadere B, Glisic S, Veljkovic N, Perovic VR, Cavanaugh DP, Branch DR 2015 F1000Res View Researchers Basic research
Concentré de recherche : Un sur un million : un modèle pour gérer les réserves de sang rare Blake J, Clarke G 2019 Blood.ca website View Researchers Clinical research
A platelet viability assay (PVA) for the diagnosis of heparin-induced thrombocytopenia Ivetic N, Arnold D, Smith J, Huynh A, Kelton J, Nazy I 2019 Platelets View Researchers Basic research