Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Targeted recruitment of optimal donors for unrelated hematopoietic cell transplantation: The Stem Cell Club process Fingrut W, Messner HA, Allan D 2020 Hematol Oncol Stem Cell Ther View Researchers New or improved product or process
Differential Leukocyte MicroRNA Responses Following Pan T Cell, Allorecognition and Allosecretome-Based Therapeutic Activation Yang X, Toyofuku WM, Scott MD 2021 Arch Immunol Ther Exp View Researchers Basic research
Soy Isoflavones Inhibit Both GPIb-IX Signaling and ?IIb?3 Outside-In Signaling via 14-3-3? in Platelet Liu M, Wang G, Xu R, Shen C, Ni H, Lai R 2021 Molecules View Researchers Basic research
Degradation of red blood cell deformability during cold storage in blood bags Islamzada E, Matthews K, Lamoureux ES, Duffy SP, Scott MD, Ma H 2021 eJHaem View Researchers Basic research
Cultured CD71+ erythroid cells modulate the host immune response Alshalani A, Beuger BM, van Bruggen R, Acker JP, Juffermans NP 2023 Transfus Med View Researchers Basic research
Behaviour based screening questions and potential donation loss using the “for the assessment of individualised risk” screening criteria: A Canadian perspective Caffrey N, Goldman M, Lewin A, Osmond L, O'Brien SF 2022 Transfus Med View Researchers MSM research
Antibody-Mediated Immune Suppression of Erythrocyte Alloimmunization Can Occur Independently from Red Cell Clearance or Epitope Masking in a Murine Model Yu H, Stowell SR, Bernardo L, Hendrickson JE, Zimring JC, Amash A, Uchikawa M, Lazarus AH 2014 J Immunol View Researchers Basic research
Bacterial neuraminidase-mediated erythrocyte desialylation provokes cell surface aminophospholipid exposure Qadri SM, Donkor DA, Nazy I, Branch DR, Sheffield WP 2018 Eur J Haematol View Researchers Basic research
Characterization of the growth modulatory activities of osteoblast conditioned media on cord blood progenitor cells Abu-Khader A, Pasha R, Ward GCD, Boisjoli G, Pineault N 2016 Cytotechnology View Researchers Basic research
Concentré de recherche: Cellules tueuses naturelles : quand les cellule perdent le nord! Ni H 2017 Blood.ca website View Researchers Basic research
Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia Li J, van der Wal DE, Zhu G, Xu M, Yougbare I, Ma L, Vadasz B, Carrim N, Grozovsky R, Ruan M, Zhu L, Zeng Q, Tao L, Zhai Z-m, Peng J, Hou M, Leytin V, Freedman J, Hoffmeister KM, Ni H 2015 Nat Commun View Researchers Basic research
Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol Lalu MM, Moher D, Marshall J, Fergusson D, Mei SH, Macleod M, Griffin G, Turgeon AF, Rudnicki M, Fishman J, Avey MT, Skidmore B, Grimshaw JM, Stewart DJ, Singh K, McIntyre L 2014 Syst Rev View Researchers Clinical research
Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury Cho N, Nguyen DH, Satkunendrarajah K, Branch DR, Fehlings MG 2012 J Neuroinflammation View Researchers Basic research
Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets Quach ME, Dragovich MA, Chen W, Syed AK, Cao W, Liang X, Deng W, De Meyer SF, Zhu G, Peng J, Ni H, Bennett CM, Hou M, Ware J, Deckmyn H, Zhang XF, Li R 2018 Blood View Researchers Basic research
Improved resolution in extracellular vesicle populations using 405 instead of 488 nm side scatter McVey MJ, Spring CM, Kuebler WM 2018 J Extracell Vesicles View Researchers Basic research
Introduction to the Special Issue: Teaching Healthcare Operations Research, Part 1 Blake J 2016 INFORMS Transactions on Education View Researchers Other
Microparticle and mitochondrial release during extended storage of different types of platelet concentrates Marcoux G, Duchez A-C, Rousseau M, Levesque T, Boudreau LH, Thibault L, Boilard E 2016 Platelets View Researchers Basic research
Nanoformulated water-soluble paclitaxel to enhance drug efficacy and reduce hemolysis side effect Gu W, Chen J, Patra P, Yang X, Gu Q, Wei L, Acker J, Kong B 2017 J Biomater Appl View Researchers Basic research
p38 mitogen-activated protein kinase regulates mitochondrial function and microvesicle release in riboflavin- and ultraviolet light–treated apheresis platelet concentrates Chen Z, Schubert P, Bakkour S, Culibrk B, Busch MP, Devine DV 2017 Transfusion View Researchers Basic research
Plasma fibronectin supports hemostasis and regulates thrombosis Wang Y, Reheman A, Spring CM, Kalantari J, Marshall AH, Wolberg AS, Gross PL, Weitz JI, Rand ML, Mosher DF, Freedman J, Ni H 2014 J Clin Invest View Researchers Basic research
Positioning new treatments in the management of immune thrombocytopenia Arnold DM 2013 Pediatr Blood Cancer View Researchers Clinical research
Riboflavin and ultraviolet illumination affects selected platelet mRNA transcript amounts differently Klein-Bosgoed C, Schubert P, Devine DV 2016 Transfusion View Researchers Basic research
Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease-activated receptor 2 cofactors that enhance infection Sutherland MR, Ruf W, Pryzdial EL 2012 Blood View Researchers Basic research
Cardiac stress biomarkers after red blood cell transfusion in patients at risk for transfusion-associated circulatory overload: a prospective observational study Callum JL, Cohen R, Cressman AM, Strauss R, Armali C, Lin Y, Pendergrast J, Lieberman L, Scales DC, Skeate R, Ross H, Cserti-Gazdewich C 2018 Transfusion View Researchers Clinical research
Electronic patient identification for sample labeling reduces wrong blood in tube errors Kaufman RM, Dinh A, Cohn CS, Fung MK, Gorlin J, Melanson S, Murphy MF, Ziman A, Elahie AL, Chasse D, Degree L, Dunbar NM, Dzik WH, Flanagan P, Gabert K, Ipe TS, Jackson B, Lane D, Raspollini E, Ray C, Sharon Y, Ellis M, Selleng K, Staves J, Yu P, Zeller M, Yazer M, BEST Collaborative 2018 Transfusion View Researchers Clinical research
Trends in IVIG use at a tertiary care Canadian center and impact of provincial use mitigation strategies: 10-year retrospective study with interrupted time series analysis Murphy MSQ, Tinmouth A, Goldman M, Chasse M, Colas JA, Saidenberg E, Shehata N, Fergusson D, Forster AJ, Wilson K 2019 Transfusion View Researchers Clinical research
Syndrome respiratoire aigu post-transfusionnel (TRALI) Petraszko T 2019 Blood.ca website View Researchers Clinical research
Glycoprotein V is a relevant immune target in patients with immune thrombocytopenia Vollenberg R, Jouni R, Norris PAA, Burg-Roderfeld M, Cooper N, Rummel MJ, Bein G, Marini I, Bayat B, Burack R, Lazarus AH, Bakchoul T, Sachs UJ 2019 Haematologica View Researchers Basic research
ResearchUnit: Fighting inflammation with inflammation Lazarus A 2019 Blood.ca website View Researchers Clinical research
Treating murine inflammatory diseases with an anti-erythrocyte antibody Crow AR, Kapur R, Koernig S, Campbell IK, Jen C-C, Mott PJ, Marjoram D, Khan R, Kim M, Brasseit J, Cruz-Leal Y, Amash A, Kahlon S, Yougbare I, Ni H, Zuercher AW, Käsermann F, Semple JW, Lazarus AH 2019 Sci Transl Med View Researchers Basic research
A comparative study of platelet factor 4-enhanced platelet activation assays for the diagnosis of heparin-induced thrombocytopenia Rubino JG, Arnold DM, Warkentin TE, Smith JW, Kelton JG, Nazy I 2021 J Thromb Haemost View Researchers Basic research
Half a Century of Wilson & Jungner: Reflections on the Governance of Population Screening Sturdy S, Miller F, Hogarth S, Armstrong N, Chakraborty P, Cressman C, Dobrow M, Flitcroft K, Grossman D, Harris R, Hoebee B, Holloway K, Kinsinger L, Krag M, Löblová O, Löwy I, Mackie A, Marshall J, O'Hallahan J, Rabeneck L, Raffle A, Reid L, Shortland G, Steele R, Tarini B, Taylor-Phillips S, Towler B, van der Veen N, Zappa M 2020 Wellcome Open Res View Researchers Other
Public Goods, or Goods for the Public? The Commercialization of Academic Health Research Holloway K, Herder M 2020 Health Matters: Evidence, Critical Social Science, and Health Care in Canada View Researchers Ethical, legal and social implications research
Transient loss of membrane integrity following intracellular ice formation in dimethyl sulfoxide-treated hepatocyte and endothelial cell monolayers William N, Acker JP 2020 Cryobiology View Researchers Basic research
Heparin-Induced Thrombocytopenia and Vaccine-Induced Immune Thrombotic Thrombocytopenia Antibodies: Fraternal-Not Identical-Twins Warkentin TE 2021 Thromb Haemost View Researchers Clinical research
Vaccine-induced immune thrombotic thrombocytopenia presenting with normal platelet count Page D, Zhu N, Sawler D, Sun HW, Turley E, Pai M, Wu C 2021 Res Pract Thromb Haemost View Researchers Clinical research
External qualification of the Web-Accessible Population Pharmacokinetic Service-Hemophilia (WAPPS-Hemo) models for octocog alfa using real patient data Chelle P, Hajducek D, Mahdi M, Young S, Iorio A, Silvertown J, Edginton A 2021 Res Pract Thromb Haemost View Researchers New or improved product or process
In Vitro Effect of Methamphetamine on Proliferation, Differentiation and Apoptosis of Adipose Tissue Stem Cells: In vitro Effect of Methamphetamine Anari L, Mehrabani D, Nasiri M, Zare S, Jamhiri I, Acker J 2022 J Pharm Sci View Researchers Basic research
Characterization of CD41(+) cells in the lymph node Dai L, Uehara M, Li X, LaBarre BA, Banouni N, Ichimura T, Lee-Sundlov MM, Kasinath V, Sullivan JA, Ni H, Barone F, Giannini S, Bahmani B, Sage PT, Patsopoulos NA, Tsokos GC, Bromberg JS, Hoffmeister K, Jiang L, Abdi R 2022 Front Immunol View Researchers Basic research
How do we forecast tomorrow's transfusion? Applying social science approaches to meet tomorrow's transfusion needs: Blood donors and donation Haw J, Holloway K, Goldman M 2023 Transfus Clin Biol View Researchers Ethical, legal & social implications research
Antigen copy number and antibody dose can determine the outcome of erythrocyte alloimmunization inducing either antibody-mediated immune suppression or enhancement in a murine model Wabnitz H, Cruz-Leal Y, Lazarus AH 2023 Transfusion View Researchers Basic research
A monoclonal antibody with anti-D–like activity in murine immune thrombocytopenia requires Fc domain function for immune thrombocytopenia ameliorative effects Yu X, Menard M, Seabright G, Crispin M, Lazarus AH 2015 Transfusion View Researchers Basic research
Amelioration of Murine Passive Immune Thrombocytopenia by IVIg and a Therapeutic Monoclonal CD44 Antibody Does Not Require the Myd88 Signaling Pathway Crow AR, Yu H, Han D, Lazarus AH 2013 PLoS One View Researchers Basic research
CD20+ B-cell depletion therapy suppresses murine CD8+ T-cell-mediated immune thrombocytopenia Guo L, Kapur R, Aslam R, Speck ER, Zufferey A, Zhao Y, Kim M, Lazarus AH, Ni H, Semple JW 2016 Blood View Researchers Basic research
Clinical Studies of Ex Vivo Expansion to Accelerate Engraftment After Umbilical Cord Blood Transplantation: A Systematic Review Kiernan J, Damien P, Monaghan M, Shorr R, McIntyre L, Fergusson D, Tinmouth A, Allan D 2016 Transfus Med Rev View Researchers Clinical research
Engineering biomaterials surfaces to modulate the host response Yu K, Mei Y, Hadjesfandiari N, Kizhakkedathu JN 2014 Colloids Surf B Biointerfaces View Researchers Basic research
Immunogenicity of murine mPEG-red blood cells and the risk of anti-PEG antibodies in human blood donors Le Y, Toyofuku WM, Scott MD 2017 Exp Hematol View Researchers Basic research
Influence of architecture of high molecular weight linear and branched polyglycerols on their biocompatibility and biodistribution Imran ul-haq M, Lai BF, Chapanian R, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
IVIG regulates the survival of human but not mouse neutrophils Schneider C, Wicki S, Graeter S, Timcheva TM, Keller CW, Quast I, Leontyev D, Djoumerska-Alexieva IK, Kasermann F, Jakob SM, Peyta D, Branch D, Cummings J, Kaufmann T, Simon H, Von Gunten S 2017 Sci Rep View Researchers Basic research
Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets Zufferey A, Speck ER, Machlus KR, Aslam R, Guo L, McVey MJ, Kim M, Kapur R, Boilard E, Italiano JE, Jr., Semple JW 2017 Blood Adv View Researchers Basic research