Our Research Publications
Updated November 2023
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Title | Authors | Year Sort ascending | Journal | Link to Article | Intended Audience | Purpose |
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FAQ: Solvent detergent (S/D) treated plasma (Octaplasma) | Mack J, Gordon R, Romans R, Webert K, Ning S, Zeller M | 2023 | Blood.ca website | View FAQ: Solvent detergent (S/D) treated plasma (Octaplasma) | Health care providers | New or improved product or process |
Circulaire d'information utilisation de composants sanguins humains: Composants plasmatiques | Stewart T | 2023 | Blood.ca website | View Circulaire d'information utilisation de composants sanguins humains: Composants plasmatiques | Health care providers | Benchmarking and standard setting |
Auditing a recently implemented massive hemorrhage protocol: feasibility of assessing pre-specified metrics and compliance | Leis M, Clarfield L, Lin Y, Gupta A, Da Luz L | 2023 | CJEM | View Auditing a recently implemented massive hemorrhage protocol: feasibility of assessing pre-specified metrics and compliance | Health care providers | Benchmarking and standard setting |
KEL1 negative red cell transfusions for females of current or future child-bearing potential: A clinical impact and feasibility study | Ning S, Morin PA, Elahie A, Li N, Liu Y, Barty R, Clarke G, Zeller M, Heddle NM | 2023 | Transfusion | View KEL1 negative red cell transfusions for females of current or future child-bearing potential: A clinical impact and feasibility study | Health care providers | Clinical research |
Cardiovascular events among recipients of hematopoietic stem cell transplantation-A systematic review and meta-analysis | Aghel N, Lui M, Wang V, Khalaf D, Mian H, Hillis C, Walker I, Leber B, Lipton JH, Aljama M, Lepic K, Berg T, Garcia-Horton A, Petropoulos J, Masoom H, Leong DP | 2023 | Bone Marrow Transplant | View Cardiovascular events among recipients of hematopoietic stem cell transplantation-A systematic review and meta-analysis | Researchers | Clinical research |
Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα | Shen C, Mackeigan DT, Shoara AA, Xu R, Bhoria P, Karakas D, Ma W, Cerenzia E, Chen Z, Hoard B, Lin L, Lei X, Zhu G, Chen P, Johnson PE, Ni H | 2023 | J Thromb Haemost | View Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα | Researchers | Basic research |
Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? | Kirkham AM, Bailey AJM, Shorr R, Lalu MM, Fergusson DA, Allan DS | 2023 | Cytotherapy | View Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? | Researchers | Clinical research |
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply | Mahamad S, Li N, Arnold DM | 2023 | J Thromb Haemost | View Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply | Researchers | Clinical research |
White paper on pandemic preparedness in the blood supply | Strengers P, O'Brien SF, Politis C, Mayr W, Seifried E, Spencer BR | 2023 | Vox Sang | View White paper on pandemic preparedness in the blood supply | Blood operators | Benchmarking and standard setting |
Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study | Leong DP, Zhang A, Breznik JA, Clare R, Huynh A, Mushtaha M, Rangarajan S, Stacey H, Kim PY, Loeb M, Denburg JA, Mertz D, Chagla Z, Nazy I, Miller MS, Bowdish DME, Duong M | 2023 | PLoS One | View Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study | Researchers | Clinical research |
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia | Gabe C, Liu Y, Duncan J, St John M, Lucier KJ, Kimmel D, Kelton JG, Arnold DM | 2023 | Platelets | View Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia | Researchers | Clinical research |
An expanded role for blood donor emerging pathogens surveillance | O’Brien SF, Goldman M, Drews S | 2023 | CMAJ | View An expanded role for blood donor emerging pathogens surveillance | Blood operators | New or improved product or process |
Proceedings of the immune thrombocytopenia summit: new concepts in mechanisms, diagnosis, and management | Mahamad S, Modi D, Al-Samkari H, Cuker A, Despotovic JM, Italiano JE, Lambert MP, Lee EJ, Rondina MT, Sholzberg M, Kruse C, Larché M, Nazy I, Miller MS, Arnold DM | 2023 | Res Pract Thromb Haemost | View Proceedings of the immune thrombocytopenia summit: new concepts in mechanisms, diagnosis, and management | Health care providers | Clinical research |
NAC Recommendations for the Use of Solvent-Detergent Plasma in Canada | Quinn JG, Pavenski K, Webert K, Ye S | 2023 | National Advisory Committee on Blood and Blood Products | View NAC Recommendations for the Use of Solvent-Detergent Plasma in Canada | Health care providers | Benchmarking and standard setting |
Adjudicating the Diagnosis of Immune Thrombocytopenia in a Clinical Research Study | Gabe C, Mahamad S, John M, Duncan J, Kelton J, Arnold D | 2023 | TH Open | View Adjudicating the Diagnosis of Immune Thrombocytopenia in a Clinical Research Study | Researchers | Clinical research |
Validation of a flow-cytometry-based red blood cell antigen phenotyping method | Liwski R, Clarke G, Cheng C, Abidi SSR, Abidi SR, Quinn JG | 2023 | Vox Sang | View Validation of a flow-cytometry-based red blood cell antigen phenotyping method | Health care providers | New or improved product or process |
Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | O’Brien SF, Reedman CN, Osiowy C, Bolotin S, Yi Q-L, Lourenço L, Lewin A, Binka M, Caffrey N, Drews SJ | 2023 | Viruses | View Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | Researchers | Clinical research |
An online immunohematology educational resource for post-graduate hematology trainees: LearnSerology.ca | Arsenault V, Yan MTS, Tait G, Lewin A, Pendergrast J | 2023 | Transfus Apher Sci | View An online immunohematology educational resource for post-graduate hematology trainees: LearnSerology.ca | Health care providers | Education research |
Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency-first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository | Kumar R, Bakeer N, Dawson J, Al-Mughairy A, Stanek J, Dunn A, Male C, Chan A, Williams S | 2023 | J Thromb Haemost | View Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency-first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository | Researchers | Basic research |
How do I/we forecast tomorrows’ transfusion: Blood components | Pereyra N, Devine DV | 2023 | Transfus Clin Biol | View How do I/we forecast tomorrows’ transfusion: Blood components | Health care providers | New or improved product or process |
Use of selective phenotyping and genotyping to identify rare blood donors in Canada | Tordon B, Montemayor C, Clarke G, O'Brien SF, Goldman M | 2023 | Vox Sang | View Use of selective phenotyping and genotyping to identify rare blood donors in Canada | Blood operators | Clinical research |
Transfusion camp: A retrospective study of self-reported impact on postgraduate trainee transfusion practice | Yeung KCY, Kapitany C, Chargé S, Callum J, Cserti-Gazdewich C, D'Empaire PP, Khandelwal A, Lieberman L, Lee C, Pavenski K, Pendergrast J, Shehata N, Hsia CC, Lavoie M, Murphy MF, Prokopchuk-Gauk O, Rahmani M, Trudeau J, Zeller MP, Lin Y | 2023 | Transfusion | View Transfusion camp: A retrospective study of self-reported impact on postgraduate trainee transfusion practice | Health care providers | Education research |
Willingness and eligibility to donate blood under 12-month and 3-month deferral policies among gay, bisexual, and other men who have sex with men in Ontario, Canada | Brennan D, Armstrong JP, Kesler M, Bekele T, Lachowksy N, Grace D, Hart TA, Souleymanov R, Adam B | 2023 | PLOS Glob Public Health | View Willingness and eligibility to donate blood under 12-month and 3-month deferral policies among gay, bisexual, and other men who have sex with men in Ontario, Canada | Researchers | MSM research |
BAY 81-8973 Efficacy and Safety in Previously Untreated and Minimally Treated Children with Severe Hemophilia A: The LEOPOLD Kids Trial | Ljung R, Chan AKC, Glosli H, Afonja O, Becker B, Tseneklidou-Stoeter D, Mancuso ME, Saulyte-Trakymiene S, Kenet G | 2023 | Thromb Haemost | View BAY 81-8973 Efficacy and Safety in Previously Untreated and Minimally Treated Children with Severe Hemophilia A: The LEOPOLD Kids Trial | Researchers | Clinical research |
The timing of gamma irradiation and its effect on cell-free and microvesicle-bound hemoglobin. The BEST collaborative study | William N, Bicahlo B, Hansen A, de Korte D, Acker JP, Biomedical Excellence for Safer Transfusion Collaborative | 2022 | Transfusion | View The timing of gamma irradiation and its effect on cell-free and microvesicle-bound hemoglobin. The BEST collaborative study | Researchers | Basic research |
Circulaire d'information utilisation de composants sanguins humains: Concentrés plaquettaires à pathogènes inactivés | Stewart T | 2022 | Blood.ca website | View Circulaire d'information utilisation de composants sanguins humains: Concentrés plaquettaires à pathogènes inactivés | Health care providers | Benchmarking and standard setting |
Exploring the reasons for low pertussis vaccine effectiveness in Ontario, Canada, 2006–2008: a Canadian Immunization Research Network study | Hughes SL, Kwong JC, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Mahmud SM, Crowcroft NS | 2022 | Can J Public Health | View Exploring the reasons for low pertussis vaccine effectiveness in Ontario, Canada, 2006–2008: a Canadian Immunization Research Network study | Regulators | Clinical research |
Comparison of perioperative practices for placement of central venous access devices (CVAD) in children with haemophilia | Kwan C, Chan AK, Koh PL, Kadir NIA, Decker K, Lim CY, Lam JCM | 2022 | J Haem Pract | View Comparison of perioperative practices for placement of central venous access devices (CVAD) in children with haemophilia | Health care providers | Clinical research |
Clinical and laboratory predictors of fetal and neonatal alloimmune thrombocytopenia | Matusiak K, Patriquin CJ, Deniz S, Dzaja N, Smith JW, Wang G, Nazy I, Kelton JG, Arnold DM | 2022 | Transfusion | View Clinical and laboratory predictors of fetal and neonatal alloimmune thrombocytopenia | Researchers | Clinical research |
Babesia microti in a Canadian blood donor and lookback in a red blood cell recipient | Drews SJ, Van Caeseele P, Bullard J, Lindsay LR, Gaziano T, Zeller MP, Lane D, Ndao M, Allen VG, Boggild AK, O'Brien SF, Marko D, Musuka C, Almiski M, Bigham M | 2022 | Vox Sang | View Babesia microti in a Canadian blood donor and lookback in a red blood cell recipient | Health care providers | Clinical research |
Hemolysis after high-dose intravenous immunoglobulin: An under-appreciated sequelae | Branch DR, Almizraq RJ, Bussel JB | 2022 | Am J Hematol | View Hemolysis after high-dose intravenous immunoglobulin: An under-appreciated sequelae | Researchers | Basic research |
Prolonged Blood Storage and Risk of Posttransfusion Acute Kidney Injury | Adegboye J, Sapatnekar S, Mascha EJ, Shah K, Lioudis M, Essber H, Cohen B, Rivas E, Heddle NM, Eikelboom JW, Ellis MH, Sharon Y, Sinha R, Kurz A, Sessler DI | 2022 | Anesthesiology | View Prolonged Blood Storage and Risk of Posttransfusion Acute Kidney Injury | Researchers | Clinical research |
Chapter 19. Pathogen-reduced platelets | Blais-Normandin I, Tordon B, Anani W, Ning S | 2022 | Clinical Guide to Transfusion | View Chapter 19. Pathogen-reduced platelets | Health care providers | Benchmarking and standard setting |
Lessons Learned from the COVID-19 Pandemic and How Blood Operators Can Prepare for the Next Pandemic | Drews SJ, O’Brien SF | 2022 | Viruses | View Lessons Learned from the COVID-19 Pandemic and How Blood Operators Can Prepare for the Next Pandemic | Blood operators | New or improved product or process |
A critical contribution in a time of crisis: Examining motivations and deterrents to COVID-19 convalescent plasma donation and future donation intentions among prospective Canadian donors | Holloway K, Campbell C, Ali R, Huyer LD, Hart D, Haw J, Brennenstuhl S, Grundy Q | 2022 | Transfus Med | View A critical contribution in a time of crisis: Examining motivations and deterrents to COVID-19 convalescent plasma donation and future donation intentions among prospective Canadian donors | Researchers | Ethical, legal & social implications research |
Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude | Li M, Tang X, Liao Z, Shen C, Cheng R, Fang M, Wang G, Li Y, Tang S, Xie L, Zhang Z, Kamau PM, Mwangi J, Lu Q, Li Y, Wang Y, MacKeigan DT, Cerenzia EG, Ni H, Lai R | 2022 | Blood | View Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude | Researchers | Basic research |
RE: A better normal in Canada will need a better detection system for emerging and re-emerging respiratory pathogens | O'Brien S, Goldman M, Drews S | 2022 | CMAJ | View RE: A better normal in Canada will need a better detection system for emerging and re-emerging respiratory pathogens | Researchers | Clinical research |
Contamination of platelet concentrates with Staphylococcus aureus induces significant modulations in platelet functionality | Yousuf B, Pasha R, Pineault N, Ramirez-Arcos S | 2022 | Vox Sang | View Contamination of platelet concentrates with Staphylococcus aureus induces significant modulations in platelet functionality | Researchers | Basic research |
The Missing Pieces to the Cold-Stored Platelet Puzzle | Zhao H, Devine DV | 2022 | Int J Mol Sci | View The Missing Pieces to the Cold-Stored Platelet Puzzle | Researchers | Basic research |
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies | Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS | 2022 | Cytotherapy | View Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies | Researchers | Clinical research |
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update | Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup | 2022 | Vox Sang | View The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update | Researchers | Benchmarking and standard setting |
Vaccine-induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources | Greinacher A, Langer F, Makris M, Pai M, Pavord S, Tran H, Warkentin TE | 2022 | J Thromb Haemost | View Vaccine-induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources | Health care providers | Clinical research |
Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination | Breznik JA, Huynh A, Zhang A, Bilaver L, Bhakta H, Stacey HD, Ang JC, Bramson JL, Nazy I, Miller MS, Denburg J, Costa AP, Bowdish DME | 2022 | J Immunol | View Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination | Health care providers | Clinical research |
THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets | Gil Gonzalez L, Fernandez-Marrero Y, Norris PAA, Tawhidi Z, Shan Y, Cruz-Leal Y, Won KD, Frias-Boligan K, Branch DR, Lazarus AH | 2022 | PLoS One | View THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets | Researchers | Basic research |
ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM | 2022 | Blood | View ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Researchers | Basic research |
Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation | Olafson C, William N, Howell A, Beaudin L, Gill B, Clarke G, Stephens S, Lopes-Carvalho D, Lane D, Schubert P, McTaggart K, Acker JP | 2022 | Transfusion | View Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation | Researchers | New or improved product or process |
Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood | Stewart T | 2022 | Blood.ca website | View Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood | Health care providers | Benchmarking and standard setting |
Circulaire d'information utilisation de composants sanguins humains: Plaquettes | Stewart T | 2022 | Blood.ca website | View Circulaire d'information utilisation de composants sanguins humains: Plaquettes | Health care providers | Benchmarking and standard setting |
Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies | Gajic-Veljanoski O, Li C, Schaink AK, Guo J, Shehata N, Charames GS, de Vrijer B, Clarke G, Pechlivanoglou P, Okun N, Kandel R, Dooley J, Higgins C, Ng V, Sikich N | 2022 | Transfusion | View Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies | Researchers | Clinical research |
HIV residual risk in Canada for apheresis source plasma donation without deferral for men who have sex with men | Aubé E, Lewin A, O'Brien SF, Grégoire Y, Pillonel J, Steele WR, Custer B, Davison KL, Germain M, Seed CR, Camirand Lemyre F, the Surveillance RA, Policy Subgroup of the ISBT Transfusion Transmitted Infectious Diseases Working Party | 2022 | Vox Sang | View HIV residual risk in Canada for apheresis source plasma donation without deferral for men who have sex with men | Blood operators | MSM research |