Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
CD4+ T-cells are unable to express the HIV natural resistance factor globotriosylceramide Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR 2013 AIDS View Researchers Basic research
Developing highly active small molecule ice recrystallization inhibitors based upon C-linked antifreeze glycoprotein analogues Trant JF, Briggs RA, Capicciotti C, Ben RN 2013 RSC Adv View Researchers Basic research
Donor iron policy: from research to practice O'Brien SF 2016 Transfusion View Researchers New or improved product or process
Enhanced Cell Surface Polymer Grafting in Concentrated and Nonreactive Aqueous Polymer Solutions Rossi NAA, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu JN 2010 J Am Chem Soc View Researchers Basic research
Fluids in sepsis and septic shock (FISSH): protocol for a pilot randomised controlled trial Rochwerg B, Millen T, Austin P, Zeller M, D'Aragon F, Jaeschke R, Masse MH, Mehta S, Lamontagne F, Meade M, Guyatt G, Cook DJ 2017 BMJ Open View Researchers Clinical research
Hepatoprotective effects of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] on alcohol-damaged primary rat hepatocyte culture in vitro Jiang W, Bian Y, Wang Z, Chang TMS 2016 Artif Cells Nanomed Biotechnol View Researchers New or improved product or process
Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study Liesner RJ, Abashidze M, Aleinikova O, Altisent C, Belletrutti MJ, Borel-Derlon A, Carcao M, Chambost H, Chan AKC, Dubey L, Ducore J, Fouzia NA, Gattens M, Gruel Y, Guillet B, Kavardakova N, El Khorassani M, Klukowska A, Lambert T, Lohade S, Sigaud M, Turea V, Wu JKM, Vdovin V, Pavlova A, Jansen M, Belyanskaya L, Walter O, Knaub S, Neufeld EJ 2017 Haemophilia View Researchers Clinical research
Influence of polymer architecture on antigens camouflage, CD47 protection and complement mediated lysis of surface grafted red blood cells Chapanian R, Constantinescu I, Rossi NA, Medvedev N, Brooks DE, Scott MD, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity Saha MN, Jiang H, Jayakar J, Reece D, Branch DR, Chang H 2010 Cancer Biol Ther View Researchers Basic research
Nouvelle cuisine: platelets served with inflammation Kapur R, Zufferey A, Boilard E, Semple JW 2015 J Immunol View Researchers Basic research
Targeting activated platelets and fibrinolysis: hitting two birds with one stone Reheman A, Xu X, Reddy EC, Ni H 2014 Circ Res View Researchers Basic research
Screening of red blood cells for extracellular vesicle content as a product quality indicator Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E 2018 Transfusion View Researchers New or improved product or process
Anti-M (French) Clarke G, Cote J, Lane D 2018 Blood.ca website View Researchers Basic research
Concentré de recherche : Dépistage d'agents pathogènes : la modélisation du risque au service de la sécurité de l'approvisionnement en sang O'Brien S 2019 Blood.ca website View Researchers Basic research
Cross-linked hemoglobin bis-tetramers from bioorthogonal coupling do not induce vasoconstriction in the circulation Wang A, Singh S, Yu B, Bloch DB, Zapol WM, Kluger R 2019 Transfusion View Researchers Basic research
Bacterial survival in whole blood depends on plasma sensitivity and resistance to neutrophil killing Taha M, Kyluik-Price D, Kumaran D, Scott MD, Toyofuku W, Ramirez-Arcos S 2019 Transfusion View Researchers Basic research
Implications of variability in cell membrane permeability for design of methods to remove glycerol from frozen-thawed erythrocytes Lahmann JM, Sanchez CC, Benson JD, Acker JP, Higgins AZ 2020 Cryobiology View Researchers Basic research
Stability of 40 cytokines/chemokines in chronically ill patients under different storage conditions Binnington B, Sakac D, Yi Q, Tong TN, Parmar N, Duong TT, Yeung RSM, Pendergrast J, Branch DR 2020 Cytokine View Researchers Basic research
50 years of Vox Sanguinis International Forums Lozano M, Dunbar NM, Devine DV 2020 Vox Sang View Researchers Benchmarking and standard setting
Could antigen loss be a potential mechanism to explain antibody-mediated immune suppression? Cruz-Leal Y, Lazarus AH 2021 Transfusion View Researchers Basic research
Evaluating blood product quality post expiry to mitigate blood shortages during the COVID-19 pandemic in Canada Turner TR, Olafson C, Mykhailova O, Xu A, Acker JP 2020 Transfusion View Researchers New or improved product or process
Industry, experts and the role of the ‘invisible college’ in the dissemination of non-invasive prenatal testing in the US Holloway K, Miller FA, Simms N 2021 Soc Sci Med View Researchers Ethical, legal and social implications research
Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion Heddle NM, Cardoso M, van der Meer PF 2020 Transfusion View Researchers Clinical research
The utility of a monocyte monolayer assay in the assessment of intravenous immunoglobulin–associated hemolysis Tong TN, Blacquiere M, Sakac D, Burke-Murphy E, Yi Q, Callum J, Cserti-Gazdewich C, Parmar N, Shehata N, Pavenski K, Lau W, Lin Y, Lieberman L, Branch DR, Pendergrast J 2020 Transfusion View Researchers New or improved product or process
Non-invasive monitoring of red blood cells during cold storage using handheld Raman spectroscopy Vardaki MZ, Schulze HG, Serrano K, Blades MW, Devine DV, Turner RFB 2021 Transfusion View Researchers New or improved product or process
Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada Sheffield WP, Bhakta V, Howell A, Jenkins C, Serrano K, Johnson N, Lin Y-CJ, Colwill K, Rathod B, Greenberg B, Gingras A-C, Evans DH, Flaumenhaft E, Beckett A, Drews SJ, Devine DV 2022 Transfusion View Researchers Basic research
Comparison of Neutrophil Function in Granulocyte Concentrates From Prednisone- and G-CSF-Treated Donors: Effect of Stimulant, Leukapheresis and Storage Murru A, Allard M-È, Paré G, Vaillancourt M, Boyer L, Cayer M-P, Vitry J, Landry P, Labrecque M-M, Robitaille N, Branch DR, Girard M, Fernandes MJ 2022 Front Med View Researchers Basic research
Lessons from vaccine-induced immune thrombotic thrombocytopenia Kelton JG, Arnold DM, Nazy I 2021 Nat Rev Immunol View Researchers Clinical research
Comparative 6-Month Wild-Type and Delta-Variant Antibody Levels and Surrogate Neutralization for Adults Vaccinated with BNT162b2 versus mRNA-1273 Grunau B, Golding L, Prusinkiewicz MA, Asamoah-Boaheng M, Armour R, Marquez AC, Jassem AN, Barakauskas V, O’Brien SF, Drews SJ, Haig S, Lavoie PM, Goldfarb DM 2022 Microbiol Spectr View Researchers Clinical research
Preservation and Storage of Cells for Therapy: Current Applications and Protocols Acker JP, Bondarovych M, Brunotte R, Buriak IA, Fuller BJ, Glasmacher B, Goltsev AM, Gregor J, Gryshkov O, Herrity K, Honegrová B, Hunt CJ, Jandová M, Johnstone BH, Kilbride P, Lánská M, Mann J, Měřička P, Musall KG, Mutsenko V, Mykhailova O, Petrenko Y, Radocha J, Sherry AM, Stacey GN, Štěrba L, Vokurková D, William N, Woods EJ 2022 Cell Engineering and Regeneration View Researchers Benchmarking and standard setting
Cross-Canada Variability in Blood Donor SARS-CoV-2 Seroprevalence by Social Determinants of Health O’Brien SF, Caffrey N, Yi Q-L, Bolotin S, Janjua NZ, Binka M, Thanh CQ, Stein DR, Lang A, Colquhoun A, Pambrun C, Reedman CN, Drews SJ 2023 Microbiol Spectr View Researchers Clinical research
The response of a human haematopoietic cell line to trehalose-loaded liposomes and their effect on post-thaw membrane integrity Scott KL, William N, Acker JP 2022 Cryobiology View Researchers Basic research
Evaluating variation in perioperative red blood cell transfusion for patients undergoing elective gastrointestinal cancer surgery Zuckerman J, Coburn N, Callum J, Mahar AL, Lin Y, Turgeon AF, McLeod R, Pearsall E, Martel G, Hallet J 2023 Surgery View Researchers Clinical research
[Study on the relationship of platelet specific-autoantibodies with therapeutic outcomes by dexamethasone in immune thrombocytopenia purpura] Chen Y, Ge J, Ruan M, Zhu L, Xie Y, Xia R, Ni H, Zeng Q 2015 Zhonghua Xue Ye Xue Za Zhi View Researchers Clinical research
Advances in umbilical cord blood stem cell expansion and clinical translation Pineault N, Abu-Khader A 2015 Exp Hematol View Researchers Other
Angiogenesis and bleeding disorders in FNAIT Yougbare I, Zdravic D, Ni H 2015 Oncotarget View Researchers Clinical research
Blood bag plasticizers influence red blood cell vesiculation rate without altering the lipid composition of the vesicles Bicalho B, Serrano K, dos Santos Pereira A, Devine D, Acker J 2016 Transfus Med Hemother View Researchers Basic research
Comparison of bacterial attachment to platelet bags with and without preconditioning with plasma Loza-Correa M, Kalab M, Yi QL, Eltringham?Smith L, Sheffield W, Ramirez-Arcos S 2017 Vox Sang View Researchers Basic research
Different doses of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation (Protocol) Estcourt LJ, Stanworth S, Doree C, Trivella M, Hopewell S, Murphy MF, Tinmouth A 2014 Cochrane Database Syst Rev View Researchers Clinical research
Effect of liposome-treated red blood cells in an anemic rat model da Silveira Cavalcante L, Feng Q, Chin-Yee I, Acker JP, Holovati JL 2016 J Liposome Res View Researchers Basic research
Erythrocyte saturation with IgG is required for inducing antibody-mediated immune suppression and impacts both erythrocyte clearance and antigen-modulation mechanisms Cruz-Leal Y, Marjoram D, Lazarus AH 2018 J Immunol View Researchers Basic research
Extracellular vesicle characteristics in stored red blood cell concentrates are influenced by the method of detection Almizraq RJ, Seghatchian J, Holovati JL, Acker JP 2017 Transfus Apher Sci View Researchers Basic research
Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G, Sadikovic B 2016 Eur J Haematol View Researchers Clinical research
Mesenchymal stromal cells from patients with acute myeloid leukemia have altered capacity to expand differentiated hematopoietic progenitors Chandran P, Le Y, Li Y, Sabloff M, Mehic J, Rosu-Myles M, Allan DS 2015 Leuk Res View Researchers Basic research
Physical Activity and Natural Anti-VIP Antibodies: Potential Role in Breast and Prostate Cancer Therapy Veljkovic M, Dopsaj V, Dopsaj M, Branch DR, Veljkovic N, Sakarellos-Daitsiotis MM, Veljkovic V, Glisic S, Colombatti A 2011 PLoS One View Researchers Basic research
Platelets in hemostasis and thrombosis: Novel mechanisms of fibrinogen-independent platelet aggregation and fibronectin-mediated protein wave of hemostasis Hou Y, Carrim N, Wang Y, Gallant RC, Marshall A, Ni H 2015 J Biomed Res View Researchers Basic research
Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain Kurbegovic A, Trudel M 2013 Hum Mol Genet View Researchers Basic research
Red blood cell processing methods and in-hospital mortality: a transfusion registry cohort study Heddle NM, Arnold DM, Acker JP, Liu Y, Barty RL, Eikelboom JW, Webert KE, Hsia CC, O'Brien SF, Cook RJ 2016 Lancet Haematol View Researchers Clinical research
Subunit-directed click coupling via doubly cross-linked hemoglobin efficiently produces readily purified functional bis-tetrameric oxygen carriers Singh S, Dubinsky-Davidchik IS, Yang Y, Kluger R 2015 Org Biomol Chem View Researchers Basic research
The neonatal Fc receptor (FcRn) is not required for IVIg or anti-CD44 monoclonal antibody–mediated amelioration of murine immune thrombocytopenia Crow AR, Suppa SJ, Chen X, Mott PJ, Lazarus AH 2011 Blood View Researchers Basic research