Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Immune thrombocytopenia (ITP) World Impact Survey (I-WISh): Impact of ITP on health-related quality of life Cooper N, Kruse A, Kruse C, Watson S, Morgan M, Provan D, Ghanima W, Arnold DM, Tomiyama Y, Santoro C, Michel M, Laborde S, Lovrencic B, Hou M, Bailey T, Taylor-Stokes G, Haenig J, Bussel JB 2021 Am J Hematol View Researchers Clinical research
Editorial on Thaler et al. long-term follow-up after successful treatment of vaccine-induced prothrombotic immune thrombocytopenia. Thromb Res 2021 in press Warkentin TE, Pai M 2021 Thromb Res View Researchers Clinical research
Complete Genome Sequence of Staphylococcus aureus CI/BAC/25/13/W, Isolated from Contaminated Platelet Concentrates in England Paredes C, Chi SI, Flint A, Weedmark K, McDonald C, Bearne J, Ramirez-Arcos S, Pagotto F 2021 Microbiol Resour Announc View Researchers Benchmarking and standard setting
Response to ‘Adverse cardiac outcomes in patients with chronic myeloid leukaemia treated with tyrosine kinase inhibitors’ Leong D, Hillis C, Aghel N, Pond G, Seow H 2021 Heart View Researchers Clinical research
Transfusion of a platelet pool contaminated with exotoxin-producing Staphylococcus aureus: a case report Chi SI, Kumaran D, Zeller M, Ramirez-Arcos S 2021 Ann Blood View Researchers Clinical research
Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A Astermark J, Olsson A, Chelle P, Täckström K, Walger M, Magnusson M, Iorio A 2021 Haemophilia View Researchers Clinical research
Complement contributions to COVID-19 Conway EM, Pryzdial ELG 2022 Curr Opin Hematol View Researchers Basic research
Data for assessing red blood cell deformability from microscopy images using deep learning Lamoureux ES, Islamzada E, Wiens MVJ, Matthews K, Duffy SP, Ma H 2023 Data Brief View Researchers New or improved product or process
Evolving policies for donors with diabetes: The Canadian experience Miller O, Caffrey N, O'Brien SF, Goldman M 2022 Vox Sang View Researchers New or improved product or process
Assessing the quality of stored red blood cells using handheld Spatially Offset Raman spectroscopy with multisource correlation analysis Vardaki MZ, Georg Schulze H, Serrano K, Blades MW, Devine DV, F. B. Turner R 2022 Spectrochim Acta A Mol Biomol View Researchers New or improved product or process
Acid sphingomyelinase mediates murine acute lung injury following transfusion of aged platelets McVey MJ, Kim M, Tabuchi A, Srbely V, Japtok L, Arenz C, Rotstein O, Kleuser B, Semple JW, Kuebler WM 2017 Am J Physiol Lung Cell Mol Physiol View Researchers Basic research
Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior Burgess A, Dubey S, Yeung S, Hough O, Eterman N, Aubert I, Hynynen K 2014 Radiology View Researchers Basic research
Bioorthogonal phase-directed copper-catalyzed azide–alkyne cycloaddition (PDCuAAC) coupling of selectively cross-linked superoxide dismutase dimers produces a fully active bis-dimer Siren EM, Singh S, Kluger R 2015 Org Biomol Chem View Researchers Basic research
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model Ren J, Ding X, Trudel M, Greer JJ, MacLean JE 2017 Sci Rep View Researchers Basic research
Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy Sun D, Shehata N, Ye XY, Gregorovich S, De France B, Arnold DM, Shah PS, Malinowski AK 2016 Blood View Researchers Clinical research
Determining the inventory impact of extended shelf life platelets with a network simulation model Blake J 2017 Transfusion View Researchers New or improved product or process
Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion Sayyar B, Dodd M, Wen J, Ma S, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2012 J Tissue Eng View Researchers Basic research
Evidence for a novel mechanism independent of myocardial iron in beta-thalassemia cardiac pathogenesis Stoyanova E, Cloutier G, Felfly H, Lemsaddek W, Ah-Son N, Trudel M 2012 PLoS One View Researchers Basic research
Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 Artif Cells Nanomed Biotechnol View Researchers Basic research
Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-platelet therapy Zhu G, Zhang Q, Reddy EC, Carrim N, Chen Y, Xu XR, Xu M, Wang Y, Hou Y, Ma L, Li Y, Rui M, Petruzziello T, Lavalle C, Stratton TW, Lei X, Reheman A, Chen P, Zhu C, Wilkins JA, Hynes RO, Freedman J, Ni H 2017 Blood View Researchers Basic research
Leaving nothing to chance: how to randomize a clinical trial Toltl LJ, Arnold DM 2012 Transfusion View Researchers Other
Membrane Type-1 Matrix Metalloproteinase Expression in Acute Myeloid Leukemia and Its Upregulation by Tumor Necrosis Factor-? Marquez-Curtis LA, Shirvaikar N, Turner AR, Mirza I, Surmawala A, Larratt LM, Janowska-Wieczorek A 2012 Cancers View Researchers Basic research
Monovalent Fc receptor blockade by an anti-Fc? receptor/albumin fusion protein ameliorates murine ITP with abrogated toxicity Yu X, Menard M, Prechl J, Bhakta V, Sheffield WP, Lazarus AH 2016 Blood View Researchers Basic research
Red blood cell antibody induced anemia causes differential degrees of tissue hypoxia in kidney and brain Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AG, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT 2018 Am J Physiol Regul Integr Comp Physiol View Researchers Basic research
Strict anaerobic Staphylococcus saccharolyticus isolates recovered from contaminated platelet concentrates fail to multiply during platelet storage Ali H, Rood IG, de Korte D, Ramirez-Arcos S 2012 Transfusion View Researchers Basic research
The cellular pathophysiology of immune thrombocytopenia Semple JW 2013 ISBT Sci Ser View Researchers Basic research
Thermal reversal of polyvalent choline phosphate, a multivalent universal biomembrane adhesive Yu X, Zou Y, Horte S, Janzen J, Kizhakkedathu JN, Brooks DE 2013 Biomacromolecules View Researchers Basic research
Verotoxin A subunit protects lymphocytes and T cell lines against X4 HIV infection in vitro Shi PL, Binnington B, Sakac D, Katsman Y, Ramkumar S, Gariepy J, Kim M, Branch DR, Lingwood C 2012 Toxins (Basel) View Researchers Basic research
ResearchUnit: One in a million: Modelling rare blood flow Blake J, Clarke G 2019 Blood.ca website View Researchers Clinical research
Effect of liposome treatment on hemorheology and metabolic profile of human red blood cells during hypothermic storage Da Silveira Cavalcante L, Acker J, Holovati J 2018 Biopreserv Biobank View Researchers Basic research
Reducing red blood cell folate testing: a case study in utilisation management Ismail O, Chin-Yee I, Gob A, Bhayana V, Rutledge A 2019 BMJ Open Quality View Researchers Basic research
Pathophysiology of immune thrombocytopenia Li J, Sullivan JA, Ni H 2018 Curr Opin Hematol View Researchers Other
Concentré de recherche : Plasma : c'est dans la poche Sheffield W, Jenkins C 2018 Blood.ca website View Researchers Basic research
An enzymatic pathway in the human gut microbiome that converts A to universal O type blood Rahfeld P, Sim L, Moon H, Constantinescu I, Morgan-Lang C, Hallam SJ, Kizhakkedathu JN, Withers SG 2019 Nat Microbiol View Researchers Basic research
Is Platelet Desialylation a Novel Biomarker and Therapeutic Target in Immune Thrombocytopenia? Li J, Sullivan J, Ni H 2020 Cell Immunol View Researchers Basic research
Population pharmacokinetics of two recombinant human coagulation factor preparations in patients with hemophilia A Hua BL, Chelle P, Yeung C, Gu J, Zhao YQ, Iorio A 2019 Zhonghua Xue Ye Xue Za Zhi View Researchers Clinical research
Current and Future Perspectives for the Cryopreservation of Cord Blood Stem Cells Jahan S, Kaushal R, Pasha R, Pineault N 2021 Transfus Med Rev View Researchers New or improved product or process
Is the COVID-19 thrombotic catastrophe complement-connected? Conway EM, Pryzdial ELG 2020 J Thromb Haemost View Researchers Basic research
Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly Niu C, Yang Y, Huynh A, Nazy I, Kaltashov IA 2020 Biophys J View Researchers Basic research
SCAR: The high-prevalence antigen 013.008 in the Scianna blood group system Srivastava K, Albasri J, Alsuhaibani OM, Aljasem HA, Bueno MU, Antonacci T, Branch DR, Denomme GA, Flegel WA 2021 Transfusion View Researchers Basic research
Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fc? receptor inhibition Norris PAA, Kaur G, Khan R, Zhu G, Ni H, Lazarus AH 2021 Blood View Researchers Basic research
An uncertain association between influenza season, recent influenza vaccination campaigns, and unconfirmed repeat reactive syphilis serology assay results in Canadian blood donors Drews SJ, Bodnar M, Gill B, Carson D, Hawes G, Yi QL, Tran V, Zhou HY, Bigham M, O'Brien SF 2022 Transfusion View Researchers Benchmarking and standard setting
Newer formulations of intravenous iron: a review of their chemistry and key safety aspects – hypersensitivity, hypophosphatemia, and cardiovascular safety Blumenstein I, Shanbhag S, Langguth P, Kalra PA, Zoller H, Lim W 2021 Expert Opin Drug Saf View Researchers Basic research
A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Robbins NF, Orjuela G, Jenkins C, Conrod V, Yi Q-L, O’Brien SF, Drews SJ 2022 Microbiol Spectr View Researchers Benchmarking and standard setting
Blood is a politic of place-making: Blackness, queerness and the construction of the donor Dryden OH 2022 Harriet’s Legacies: Race, Historical Memory, and Futures in Canada View Researchers MSM research
Automated closed volume reduction process for apheresis stem cell grafts: From development to clinical implementation Howell A, Letcher B, Murphy K, Elmoazzen H, Petraszko T, Acker JP, Pineault N, Holovati JL 2022 Transfusion View Researchers New or improved product or process
A data-informed system to manage scarce blood product allocation in a randomized controlled trial of convalescent plasma Li N, Zeller MP, Shih AW, Heddle NM, St. John M, Bégin P, Callum J, Arnold DM, Akbari-Moghaddam M, Down DG, Jamula E, Devine DV, Tinmouth A 2022 Transfusion View Researchers Clinical research
Current status of rapid bacterial detection methods for platelet components: A 20-year review by the ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria Schmidt M, Ramirez-Arcos S, Stiller L, McDonald C, ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria 2022 Vox Sang View Researchers Benchmarking and standard setting
An official American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death Gries CJ, White DB, Truog RD, Dubois J, Cosio CC, Dhanani S, Chan KM, Corris P, Dark J, Fulda G, Glazier AK, Higgins R, Love R, Mason DP, Nakagawa TA, Shapiro R, Shemie S, Tracy MF, Travaline JM, Valapour M, West L, Zaas D, Halpern SD, American Thoracic Society Health Policy Committee 2013 Am J Respir Crit Care Med View Researchers Benchmarking and standard setting
Attitudes toward Reciprocity Systems for Organ Donation and Allocation for Transplantation Burkell JA, Chandler JA, Shemie SD 2013 J Health Polit Policy Law View Researchers Other