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The issue:

Intravenous immunoglobulin (IVIg) is a plasma-derived drug used to treat a wide range of conditions and demand for this expensive product keeps growing. In Canada, IVIg is provided to hospitals by Canadian Blood Services. The Centre for Innovation facilitates research into IVIg to understand the pathogenesis of immune conditions treated by IVIg [e.g. immune thrombocytopenia (ITP) and fetal and neonatal alloimmune thrombocytopenia (FNAIT)], explain the poorly understood mechanisms of action of IVIg, and develop IVIG alternatives.