Selected donations may be also tested for cytomegalovirus (CMV) antibody, or the presence of Immunoglobulin A (IgA) antibodies for at-risk patients that may require blood components tested for CMV or IgA antibodies. Donations for further manufacturing into plasma protein products are also tested for Parvovirus B19.
Our routine process is that all platelet components are cultured for bacteria 36 hours after collection, and then held for six hours after bacteria culture bottle inoculation. Platelet components are issued to hospitals for transfusion only if the culture results are negative at the time of issue. Cultures are incubated for six days, and hospitals are notified if the component bacteria culture becomes positive. For further information on bacteria testing, see Customer Letters 2007-03 and 2017-31. Bacterial detection of pooled platelets using the Bacti/ALERT detection system was implemented as part of the buffy coat component production method implementation (Edmonton site pilot 2005, Vancouver site pilot 2007, and national rollout 2008). Bacterial detection of apheresis platelets using the Bacti/ALERT detection system was implemented in May 2004.
Additional information can be found in the Clinical Guide to Transfusion.