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Sheffield, William

Back To Our Investigators
 

William Sheffield

Contact Dr. Sheffield

Mailing Address:

McMaster University
4N66 Health Sciences Centre
1280 Main Street West
Hamilton, ON, L8S 4K1
Canada

Phone Number: 905-525-9140 ext. 22701
Email: sheffiel@mcmaster.ca

Other Website
LinkedIn
PubMed
Google Scholar

Associate Director, Research, and
Senior Scientist

Centre for Innovation
Canadian Blood Services

Professor
Department of Pathology and Molecular Medicine
McMaster University

Plasma – A Source of Medication and Inspiration

Research in the Sheffield laboratory focuses on plasma, the liquid component of the blood. Plasma components regulate hemostasis, and plasma is the only product of whole blood processing that can be readily frozen, thawed and transfused.

Why is this important?

Understanding the biological functions of plasma components and their efficacy in the regulation of hemostasis can provide insight towards the development of better transfusion practice and more efficient utilization of donated plasma.

[Read more]

Plasma Manufacturing and Quality Assessment

Our research supports the provision of high quality plasma and plasma products for Canadian patients.

Why is this important?

Our scientific studies provide the blood system with evidence upon which more rational regulations and/or improved processes can be based.

[Read more]

Plasma Proteins and Recombinant Engineered Plasma Proteins

Inspired by the properties of natural plasma proteins and using recombinant DNA technology, our group is developing novel plasma proteins to target specific therapeutic applications.

Why is this important?

There are as yet unmet therapeutic needs in the areas of coagulation, and our research efforts aim to advance discovery in this field through the optimization of naturally occurring plasma proteins. Working in this area also gives us expertise with which to appraise new commercial plasma protein products to inform decisions on whether Canadian Blood Services should distribute them to Canadian hospitals.

[Read more]

Leadership Roles:

2009 - Current

Member, Scientific and Medical Advisory Committee, Hema-Quebec 

Education:

  • Doctor of Philosophy in Biochemistry, McGill University

  • Bachelor of Science (Hons) Biochemistry, McGill University