Research

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Scott, Mark

Back To Our Investigators
 

Mark Scott

Contact Dr. Scott

Mailing Address:

Centre for Blood Research
2350 Health Sciences Mall
Vancouver, BC V6T 1Z3
Canada

Phone Number: 604-822-4976
Email: mdscott@mail.ubc.ca

Other Website
LinkedIn
PubMed
Google Scholar

Senior Scientist
Centre for Innovation
Canadian Blood Services

Investigator
Centre for Blood Research
University of British Columbia

Clinical Professor
Pathology and Laboratory Medicine
University of British Columbia

Use of Immunocamouflaged Cells in Transfusion and Transplantation Medicine

Dr. Mark Scott has pioneered the immunocamouflage of red blood cells, leukocytes and platelets. This novel, patented technology relies on the chemical attachment of biologically safe polymers on cell membranes to camouflage cell surface antigens.

Why is this important?

Immunocamouflaged cells and tissues hold great therapeutic promise in transfusion and transplantation medicine. For example, immunocamouflaged red blood cells could meet the often urgent needs of chronically transfused patients who have alloimmunization and for whom matched donors can be nearly impossible to find. Dr. Scott’s research has yielded over 20 issued and pending patents in the fields of bioengineering, hematology, immunology, virology and redox biology.

[Read more]

Polymer-Based Antiviral Gel

Immunocamouflage also has application in the inactivation of viruses and/or prevention of viral infections.

Why is this important?

Viral infections are difficult to prevent due to our inability to effectively vaccinate against most viruses. Dr. Scott’s research has led to the development of an antiviral gel that, unlike vaccinations, is effective against a broad spectrum of viruses.

[Read more]

Serum-Derived microRNA Therapeutics

The third major area of interest in Dr. Scott’s laboratory has been the development of microRNA (miRNA) based biologics for the treatment and prevention of autoimmune diseases. 

Why is this important?

Current immunosuppressive drugs exhibit high toxicity and unwanted side effects. These natural, blood serum derived, miRNA-based therapeutics exhibit low toxicity and yet provide potent immune regulatory effects that may be useful in treating a broad range of autoimmune diseases.  

[Read more]

Leadership Roles:

2011 - Current

Member, Scientific Advisory Board, LightIntegra Technologies

2007 - 2013

Associate Director for Intellectual Property and Business Development, Canadian Blood Services

Education:

 

 

  • Doctor of Philosophy in Pathology and Laboratory Medicine, University of Minnesota, Minneapolis, Minnesota, USA

  • Master of Arts in Science, Western State Colorado University, Gunnison, Colorado, USA

  • Bachelor of Arts in Biology and Psychology, Western State Colorado University, Gunnison, Colorado, USA