Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis Kosan C, Rashkovan M, Ross J, Schaffer AM, Saba I, Lemsaddek W, Trudel M, Moroy T 2014 Am J Blood Res View Researchers Basic research
Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD 2018 J Cardiothorac Vasc Anesth View Researchers Clinical research
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates Alabdullatif M, Atreya CD, Ramirez-Arcos S 2018 Transfusion View Researchers New or improved product or process
Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions Alshalani A, Li W, Juffermans NP, Seghatchian J, Acker JP 2019 Transfus Apher Sci View Researchers Basic research
Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV 2019 Transfusion View Researchers New or improved product or process
Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 Crowcroft NS, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Mahmud SM, Kwong JC 2019 Vaccine View Researchers Clinical research
ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group Goel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So – Osman C, Wood E, Devine DV, Spitalnik SL, the ISBT COVID-19 Working Group 2021 Vox Sang View Researchers Clinical research
COVID-19 Case-Age Distribution: Correction for Differential Testing by Age Fisman D, Greer A, Hillmer M, O'Brien S, Drews SJ, Tuite A 2020 medRxiv View Researchers Clinical research
Transitioning to Full Field Digital Mammography in Nova Scotia: Using Interrupted Time Series Methods to Study the Impact of Technology Change on Mammography Volumes Brydon M, Kephart G, Payne JI, Blake J 2020 J Med Imaging Radiat Sci View Researchers New or improved product or process
DNA Mediated Blood Coagulation: Extracellular DNA Accelerates Fibrinogen Polymerization By Thrombin Independent of Contact Pathway Vappala S, Straus S, Pryzdial EL, Conway E, Kizhakkedathu J 2021 Blood View Researchers Basic research
Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles Schubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV 2021 Transfusion View Researchers New or improved product or process
Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts Kaushal R, Jahan S, McGregor C, Pineault N 2022 Cytotherapy View Researchers New or improved product or process
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O'Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G 2022 Sci Rep View Researchers Clinical research
Thymic stromal lymphopoietin induces platelet mitophagy and promotes thrombosis in Kawasaki disease Fu L, MacKeigan DT, Gong Q, Che D, Xu Y, Pi L, Sun C, Yu H, Chen K, Zhou H, Jiang Z, Wang Z, Zhang L, Cerenzia EG, Ni H, Gu X 2023 Brit J Haem View Researchers Clinical research
Blood donor eligibility criteria for medical conditions: A BEST collaborative study Jacquot C, Tiberghien P, van den Hurk K, Ziman A, Shaz B, Apelseth TO, Goldman M, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Vox Sang View Researchers Benchmarking and standard setting
SARS-CoV-2 Seroprevalence among Canadian Blood Donors: The Advance of Omicron O’Brien SF, Caffrey N, Yi Q-L, Pambrun C, Drews SJ 2022 Viruses View Researchers Clinical research
Prevalence of selected bleeding and thrombotic events in persons with hemophilia versus the general population: A scoping review Shapiro AD, Hardesty BM, Peyvandi F, Iorio A 2023 Res Pract Thromb Haemost View Researchers Clinical research
Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy Chen P, Li C, Lang S, Zhu G, Reheman A, Spring CM, Freedman J, Ni H 2010 Blood View Researchers Basic research
Comparison of detection methods for cell surface globotriaosylceramide Kim M, Binnington B, Sakac D, Fernandes KR, Shi SP, Lingwood CA, Branch DR 2011 J Immunol Methods View Researchers Basic research
Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process Gunz A, McNally J, Whyte H, O'Hearn K, Foster J, Parker M, Dhanani S 2016 J Pediatr Intensive Care View Researchers Clinical research
Differential Expression Analysis by RNA-Seq Reveals Perturbations in the Platelet mRNA Transcriptome Triggered by Pathogen Reduction Systems Osman A, Hitzler WE, Ameur A, Provost P 2015 PLoS One View Researchers Basic research
Effect of platelet additive solution on bacterial dynamics and their influence on platelet quality in stored platelet concentrates Greco CA, Zhang JG, Kalab M, Yi Q-L, Ramirez-Arcos SM, Gyongyossy-Issa MIC 2010 Transfusion View Researchers Basic research
E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1alpha/CXCR4 Sun J, Li Y, Graziani GM, Filion L, Allan DS 2013 PLoS One View Researchers Basic research
Extracellular vesicles in transfusion-related immunomodulation and the role of blood component manufacturing Almizraq RJ, Seghatchian J, Acker JP 2016 Transfusion and Apheresis Science View Researchers Basic research
Human bone marrow mesenchymal stromal cell-derived osteoblasts promote the expansion of hematopoietic progenitors through Beta-catenin and Notch signaling pathways Michalicka M, Boisjoli G, Jahan S, Hovey O, Doxtator E, Abu-Khader A, Pasha R, Pineault N 2017 Stem Cells Dev View Researchers Basic research
Mice with deleted multimerin 1 and ?-synuclein genes have impaired platelet adhesion and impaired thrombus formation that is corrected by multimerin 1 Reheman A, Tasneem S, Ni H, Hayward CPM 2010 Thromb Res View Researchers Basic research
Mouse background and IVIG dosage are critical in establishing the role of inhibitory Fcgamma receptor for the amelioration of experimental ITP Leontyev D, Katsman Y, Branch DR 2012 Blood View Researchers Basic research
Physical characterization of hematopoietic stem cells using multidirectional label-free light scatterings Shahin H, Gupta M, Janowska-Wieczorek A, Rozmus W, Tsui YY 2016 Optics Express View Researchers Basic research
Red blood cell replacement, or nanobiotherapeutics with enhanced red blood cell functions? Chang TMS 2015 Artif Cells Nanomed Biotechnol View Researchers Basic research
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions Singh S, Kluger R 2016 Biochemistry View Researchers Basic research
The effect of grafted methoxypoly(ethylene glycol) chain length on the inhibition of respiratory syncytial virus (RSV) infection and proliferation Sutton TC, Scott MD 2010 Biomaterials View Researchers Basic research
The nonhemostatic immune functions of platelets Kapur R, Semple JW 2016 Semin Hematol View Researchers Basic research
Translational feasibility of soluble nanobiotherapeutics with enhanced red blood cell functions Chang TMS 2017 Artif Cells Nanomed Biotechnol View Researchers New or improved product or process
Vox Sanguinis International Forum on donor notification and counselling strategies for markers of transfusion-transmissible infections Sharma RR, Lozano M, Fearon M, Bigham M, Djoudi R, Gallian P, Woimant G, Lee C, Leung JNS, Tsoi WC, Marwaha N, Sachdev S, Tadokoro K, Tani Y, Matsukura H, Gbuz So O, Shantseva N, Zhiburt E, Hindawi S, Chay J, Huang T, Teo D, Moleli N, Oyonarte S, Jayasekara SBA, Bokhorst A, van den Burg P, Hewitt P, Bianco C, Kessler D 2017 Vox Sang View Researchers Clinical research
Concentré de recherche: Rôle du groupe sanguin dans le déclenchement d'une hémolyse après l'administration d'immunoglobulines Branch D 2018 Blood.ca website View Researchers Basic research
Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water Devine DV 2018 JAMA Oncol View Researchers New or improved product or process
Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin MacIsaac J, Siddiqui R, Jamula E, Li N, Baker S, Webert KE, Evanovitch D, Heddle NM, Arnold DM 2018 Transfusion View Researchers Clinical research
GPIb? is required for platelet-mediated hepatic thrombopoietin generation Xu M, Li J, Neves MAD, Zhu G, Carrim N, Yu R, Gupta S, Marshall J, Rotstein O, Peng J, Hou M, Kunishima S, Ware J, Branch DR, Lazarus A, Ruggeri ZM, Freedman J, Ni H 2018 Blood View Researchers Basic research
Prevalence of Babesia in Canadian blood donors: June–October 2018 Tonnetti L, O'Brien SF, Grégoire Y, Proctor MC, Drews SJ, Delage G, Fearon MA, Brès V, Linnen JM, Stramer SL 2019 Transfusion View Researchers Clinical research
Antiviral anticoagulation Pryzdial ELG, Sutherland MR, Lin BH, Horwitz M 2020 Res Pract Thromb Haemost View Researchers Basic research
FcgammaRI and FcgammaRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH 2021 Haematologica View Researchers Basic research
Pragmatic, double-blind, randomised trial evaluating the impact of red blood cell donor sex on recipient mortality in an academic hospital population: the innovative Trial Assessing Donor Sex (iTADS) protocol Fergusson DA, Chassé M, Tinmouth A, Acker JP, English S, Forster AJ, Hawken S, Shehata N, Thavorn K, Wilson K, Tuttle A, Perelman I, Cober N, Maddison H, Tokessy M 2021 BMJ Open View Researchers Clinical research
A simple protein-based surrogate neutralization assay for SARS-CoV-2 Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis Ii AP, Girardin RC, Rathod B, Wang J, Barrios-Rodiles M, Colwill K, McGeer A, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC 2020 JCI Insight View Researchers New or improved product or process
From demand forecasting to inventory ordering decisions for red blood cells through integrating machine learning, statistical modeling, and inventory optimization Li N, Arnold DM, Down DG, Barty R, Blake J, Chiang F, Courtney T, Waito M, Trifunov R, Heddle NM 2022 Transfusion View Researchers New or improved product or process
The authors reply Iba T, Levy JH, Warkentin TE 2022 Crit Care Med View Researchers Clinical research
SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Irvine MA, Reicherz F, Coombs D, O’Reilly C, Sediqi S, Razzaghian HR, Sadarangani M, O’Brien SF, Lavoie PM 2021 medRxiv View Researchers Clinical research
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y 2022 Clin Transl Immunol View Researchers New or improved product or process
SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia Appelbaum J, Arnold DM, Kelton JG, Gernsheimer T, Jevtic SD, Ivetic N, Smith JW, Nazy I 2022 Blood Adv View Researchers Basic research
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O’Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research