Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis | Dzandzi JPK, Beckford Vera DR, Genady AR, Albu SA, Eltringham-Smith LJ, Capretta A, Sheffield WP, Valliant JF | 2015 | J Org Chem | View Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis | Researchers | Basic research |
Herpesviruses enhance fibrin clot lysis | Gershom ES, Vanden Hoek AL, Meixner SC, Sutherland MR, Pryzdial EL | 2012 | Thromb Haemost | View Herpesviruses enhance fibrin clot lysis | Researchers | Basic research |
Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes | Marjoram D, Cruz-Leal Y, Bernardo L, Le NPL, Crispin M, Yu X, Uchikawa M, Lazarus AH | 2017 | Blood | View Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes | Researchers | Basic research |
In-Gel Technology for PCR Genotyping and Pathogen Detection | Atrazhev A, Manage DP, Stickel AJ, Crabtree HJ, Pilarski LM, Acker JP | 2010 | Anal Chem | View In-Gel Technology for PCR Genotyping and Pathogen Detection | Researchers | New or improved product or process |
Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis | Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M | 2012 | Mol Cell Biol | View Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis | Researchers | Basic research |
Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells | Abdelbaset-Ismail A, Borkowska S, Janowska-Wieczorek A, Tonn T, Rodriguez C, Moniuszko M, Bolkun L, Koloczko J, Eljaszewicz A, Ratajczak J, Ratajczak MZ, Kucia M | 2015 | Oncotarget | View Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells | Researchers | Basic research |
Peculiarities of studying the effects of pathogen reduction technologies on platelets | Osman A, Hitzler WE, Provost P | 2016 | Proteomics Clin Appl | View Peculiarities of studying the effects of pathogen reduction technologies on platelets | Researchers | Basic research |
Prevention of hemolytic disease of the fetus and newborn: what have we learned from animal models? | Cruz-Leal Y, Marjoram D, Lazarus AH | 2017 | Curr Opin Hematol | View Prevention of hemolytic disease of the fetus and newborn: what have we learned from animal models? | Researchers | Basic research |
Raman spectroscopy as a novel tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units | Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB | 2016 | Analyst | View Raman spectroscopy as a novel tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units | Researchers | New or improved product or process |
Targeting FcRs to treat antibody-dependent autoimmunity | Yu X, Lazarus AH | 2016 | Autoimmun Rev | View Targeting FcRs to treat antibody-dependent autoimmunity | Researchers | Other |
The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review | Bennett S, Baker LK, Martel G, Shorr R, Pawlik TM, Tinmouth A, McIsaac DI, Hébert PC, Karanicolas PJ, McIntyre L, Turgeon AF, Barkun J, Fergusson D | 2017 | HPB | View The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review | Researchers | Clinical research |
The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis | Kosan C, Rashkovan M, Ross J, Schaffer AM, Saba I, Lemsaddek W, Trudel M, Moroy T | 2014 | Am J Blood Res | View The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis | Researchers | Basic research |
Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial | Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD | 2018 | J Cardiothorac Vasc Anesth | View Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial | Researchers | Clinical research |
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates | Alabdullatif M, Atreya CD, Ramirez-Arcos S | 2018 | Transfusion | View Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates | Researchers | New or improved product or process |
Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions | Alshalani A, Li W, Juffermans NP, Seghatchian J, Acker JP | 2019 | Transfus Apher Sci | View Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions | Researchers | Basic research |
Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood | Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV | 2019 | Transfusion | View Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood | Researchers | New or improved product or process |
Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 | Crowcroft NS, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Mahmud SM, Kwong JC | 2019 | Vaccine | View Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 | Researchers | Clinical research |
ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group | Goel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So – Osman C, Wood E, Devine DV, Spitalnik SL, the ISBT COVID-19 Working Group | 2021 | Vox Sang | View ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group | Researchers | Clinical research |
COVID-19 Case-Age Distribution: Correction for Differential Testing by Age | Fisman D, Greer A, Hillmer M, O'Brien S, Drews SJ, Tuite A | 2020 | medRxiv | View COVID-19 Case-Age Distribution: Correction for Differential Testing by Age | Researchers | Clinical research |
Transitioning to Full Field Digital Mammography in Nova Scotia: Using Interrupted Time Series Methods to Study the Impact of Technology Change on Mammography Volumes | Brydon M, Kephart G, Payne JI, Blake J | 2020 | J Med Imaging Radiat Sci | View Transitioning to Full Field Digital Mammography in Nova Scotia: Using Interrupted Time Series Methods to Study the Impact of Technology Change on Mammography Volumes | Researchers | New or improved product or process |
Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study | Kuter DJ, Rogers KA, Boxer MA, Choi M, Agajanian R, Arnold DM, Broome CM, Field JJ, Murakhovskaya I, Numerof R, Tong S | 2022 | Am J Hematol | View Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study | Researchers | Clinical research |
An intron c.149-2632T>A change in RHD is associated with aberrant transcription and very weak D phenotype | Floch A, Vege S, Berardi P, Hannon J, Ochoa-Garay G, Lomas-Francis C, Westhoff CM | 2022 | Transfusion | View An intron c.149-2632T>A change in RHD is associated with aberrant transcription and very weak D phenotype | Researchers | Clinical research |
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients | Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP | 2022 | Blood Adv | View Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients | Researchers | Clinical research |
Humoral and Cellular Response of Transplant Recipients to a Third Dose of mRNA SARS-CoV-2 Vaccine: A Systematic Review and Meta-analysis | Bailey AJM, Maganti HB, Cheng W, Shorr R, Arianne Buchan C, Allan DS | 2023 | Transplantation | View Humoral and Cellular Response of Transplant Recipients to a Third Dose of mRNA SARS-CoV-2 Vaccine: A Systematic Review and Meta-analysis | Researchers | Basic research |
A Survey of Patient Experience in CML: American and Canadian Perspectives | Hillis C, Flynn KE, Goldman EH, Moreira-Lucas TS, Visentini J, Dorman S, Ballinger R, Byrnes HF, De Palma A, Barbier V, Machado L, Atallah E | 2023 | Patient Prefer Adherence | View A Survey of Patient Experience in CML: American and Canadian Perspectives | Researchers | Clinical research |
Database-driven research and big data analytic approaches in transfusion medicine | Ning S, Li N, Barty R, Arnold D, Heddle NM | 2022 | Transfusion | View Database-driven research and big data analytic approaches in transfusion medicine | Researchers | Clinical research |
A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion | Qadri SM, Liu Y, Barty RL, Heddle NM, Sheffield WP | 2022 | Vox Sang | View A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion | Researchers | Clinical research |
Concentré de recherche: Évaluation de la sécurité des pompes à perfusion pour les transfusions de globules rouges | Wolfe A | 2022 | Blood.ca website | View Concentré de recherche: Évaluation de la sécurité des pompes à perfusion pour les transfusions de globules rouges | Researchers | Benchmarking and standard setting |
Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia | Yougbare I, Tai WS, Zdravic D, Oswald BE, Lang S, Zhu G, Leong-Poi H, Qu D, Yu L, Dunk C, Zhang J, Sled JG, Lye SJ, Brkic J, Peng C, Hoglund P, Croy BA, Adamson SL, Wen XY, Stewart DJ, Freedman J, Ni H | 2017 | Nat Commun | View Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia | Researchers | Basic research |
Comparison of detection methods for cell surface globotriaosylceramide | Kim M, Binnington B, Sakac D, Fernandes KR, Shi SP, Lingwood CA, Branch DR | 2011 | J Immunol Methods | View Comparison of detection methods for cell surface globotriaosylceramide | Researchers | Basic research |
Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process | Gunz A, McNally J, Whyte H, O'Hearn K, Foster J, Parker M, Dhanani S | 2016 | J Pediatr Intensive Care | View Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process | Researchers | Clinical research |
Differential Expression Analysis by RNA-Seq Reveals Perturbations in the Platelet mRNA Transcriptome Triggered by Pathogen Reduction Systems | Osman A, Hitzler WE, Ameur A, Provost P | 2015 | PLoS One | View Differential Expression Analysis by RNA-Seq Reveals Perturbations in the Platelet mRNA Transcriptome Triggered by Pathogen Reduction Systems | Researchers | Basic research |
Effect of platelet additive solution on bacterial dynamics and their influence on platelet quality in stored platelet concentrates | Greco CA, Zhang JG, Kalab M, Yi Q-L, Ramirez-Arcos SM, Gyongyossy-Issa MIC | 2010 | Transfusion | View Effect of platelet additive solution on bacterial dynamics and their influence on platelet quality in stored platelet concentrates | Researchers | Basic research |
E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1alpha/CXCR4 | Sun J, Li Y, Graziani GM, Filion L, Allan DS | 2013 | PLoS One | View E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1alpha/CXCR4 | Researchers | Basic research |
Extracellular vesicles in transfusion-related immunomodulation and the role of blood component manufacturing | Almizraq RJ, Seghatchian J, Acker JP | 2016 | Transfusion and Apheresis Science | View Extracellular vesicles in transfusion-related immunomodulation and the role of blood component manufacturing | Researchers | Basic research |
Human bone marrow mesenchymal stromal cell-derived osteoblasts promote the expansion of hematopoietic progenitors through Beta-catenin and Notch signaling pathways | Michalicka M, Boisjoli G, Jahan S, Hovey O, Doxtator E, Abu-Khader A, Pasha R, Pineault N | 2017 | Stem Cells Dev | View Human bone marrow mesenchymal stromal cell-derived osteoblasts promote the expansion of hematopoietic progenitors through Beta-catenin and Notch signaling pathways | Researchers | Basic research |
Mice with deleted multimerin 1 and ?-synuclein genes have impaired platelet adhesion and impaired thrombus formation that is corrected by multimerin 1 | Reheman A, Tasneem S, Ni H, Hayward CPM | 2010 | Thromb Res | View Mice with deleted multimerin 1 and ?-synuclein genes have impaired platelet adhesion and impaired thrombus formation that is corrected by multimerin 1 | Researchers | Basic research |
Mouse background and IVIG dosage are critical in establishing the role of inhibitory Fcgamma receptor for the amelioration of experimental ITP | Leontyev D, Katsman Y, Branch DR | 2012 | Blood | View Mouse background and IVIG dosage are critical in establishing the role of inhibitory Fcgamma receptor for the amelioration of experimental ITP | Researchers | Basic research |
Physical characterization of hematopoietic stem cells using multidirectional label-free light scatterings | Shahin H, Gupta M, Janowska-Wieczorek A, Rozmus W, Tsui YY | 2016 | Optics Express | View Physical characterization of hematopoietic stem cells using multidirectional label-free light scatterings | Researchers | Basic research |
Red blood cell replacement, or nanobiotherapeutics with enhanced red blood cell functions? | Chang TMS | 2015 | Artif Cells Nanomed Biotechnol | View Red blood cell replacement, or nanobiotherapeutics with enhanced red blood cell functions? | Researchers | Basic research |
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions | Singh S, Kluger R | 2016 | Biochemistry | View Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions | Researchers | Basic research |
The effect of grafted methoxypoly(ethylene glycol) chain length on the inhibition of respiratory syncytial virus (RSV) infection and proliferation | Sutton TC, Scott MD | 2010 | Biomaterials | View The effect of grafted methoxypoly(ethylene glycol) chain length on the inhibition of respiratory syncytial virus (RSV) infection and proliferation | Researchers | Basic research |
The nonhemostatic immune functions of platelets | Kapur R, Semple JW | 2016 | Semin Hematol | View The nonhemostatic immune functions of platelets | Researchers | Basic research |
Translational feasibility of soluble nanobiotherapeutics with enhanced red blood cell functions | Chang TMS | 2017 | Artif Cells Nanomed Biotechnol | View Translational feasibility of soluble nanobiotherapeutics with enhanced red blood cell functions | Researchers | New or improved product or process |
Vox Sanguinis International Forum on donor notification and counselling strategies for markers of transfusion-transmissible infections | Sharma RR, Lozano M, Fearon M, Bigham M, Djoudi R, Gallian P, Woimant G, Lee C, Leung JNS, Tsoi WC, Marwaha N, Sachdev S, Tadokoro K, Tani Y, Matsukura H, Gbuz So O, Shantseva N, Zhiburt E, Hindawi S, Chay J, Huang T, Teo D, Moleli N, Oyonarte S, Jayasekara SBA, Bokhorst A, van den Burg P, Hewitt P, Bianco C, Kessler D | 2017 | Vox Sang | View Vox Sanguinis International Forum on donor notification and counselling strategies for markers of transfusion-transmissible infections | Researchers | Clinical research |
Concentré de recherche: Rôle du groupe sanguin dans le déclenchement d'une hémolyse après l'administration d'immunoglobulines | Branch D | 2018 | Blood.ca website | View Concentré de recherche: Rôle du groupe sanguin dans le déclenchement d'une hémolyse après l'administration d'immunoglobulines | Researchers | Basic research |
Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water | Devine DV | 2018 | JAMA Oncol | View Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water | Researchers | New or improved product or process |
Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin | MacIsaac J, Siddiqui R, Jamula E, Li N, Baker S, Webert KE, Evanovitch D, Heddle NM, Arnold DM | 2018 | Transfusion | View Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin | Researchers | Clinical research |
GPIb? is required for platelet-mediated hepatic thrombopoietin generation | Xu M, Li J, Neves MAD, Zhu G, Carrim N, Yu R, Gupta S, Marshall J, Rotstein O, Peng J, Hou M, Kunishima S, Ware J, Branch DR, Lazarus A, Ruggeri ZM, Freedman J, Ni H | 2018 | Blood | View GPIb? is required for platelet-mediated hepatic thrombopoietin generation | Researchers | Basic research |
Prevalence of Babesia in Canadian blood donors: June–October 2018 | Tonnetti L, O'Brien SF, Grégoire Y, Proctor MC, Drews SJ, Delage G, Fearon MA, Brès V, Linnen JM, Stramer SL | 2019 | Transfusion | View Prevalence of Babesia in Canadian blood donors: June–October 2018 | Researchers | Clinical research |