Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study Cognasse F, Hamzeh Cognasse H, Eyraud MA, Prier A, Arthaud CA, Tiberghien P, Begue S, de Korte D, Gouwerok E, Greinacher A, Aurich K, Noorman F, Dumont L, Kelly K, Cloutier M, Bazin R, Cardigan R, Huish S, Smethurst P, Devine D, Schubert P, Johnson L, Marks DC, Biomedical Excellence for Safer Transfusion Collaborative 2023 Transfusion View Researchers Basic research
HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA 2022 Transfusion View Researchers MSM research
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Benchmarking and standard setting
A lab-on-chip for malaria diagnosis and surveillance Taylor BJ, Howell A, Martin KA, Manage DP, Gordy W, Campbell SD, Lam S, Jin A, Polley SD, Samuel RA, Atrazhev A, Stickel AJ, Birungi J, Mbonye AK, Pilarski LM, Acker JP, Yanow SK 2014 Malar J View Researchers Basic research
Applications of Liposomes in Biopreservation Da Silveira Cavalcante L, Holovati J, Acker J 2016 Multiscale technologies for cryomedicine: implementation from nano to macroscale View Researchers Basic research
Biomonitoring of Arsenic in Urine and Saliva of Children Playing on Playgrounds Constructed from Chromated Copper Arsenate-Treated Wood Lew K, Acker JP, Gabos S, Le XC 2010 Environ Sci Technol View Researchers Other
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV 2014 Sci Rep View Researchers Basic research
Emerging Role for Use of Liposomes in the Biopreservation of Red Blood Cells Holovati JL, Acker JP 2011 Transfus Med Hemother View Researchers Basic research
Fibronectin: extra domain brings extra risk? Wang Y, Ni H 2015 Blood View Researchers Other
Immunocamouflage of latex surfaces by grafted methoxypoly(ethylene glycol) (mPEG): proteomic analysis of plasma protein adsorption Le Y, Li L, Wang D, Scott MD 2012 Sci China Life Sci View Researchers Basic research
Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa Sheffield WP, Eltringham-Smith LJ 2011 BMC Biotechnol View Researchers Basic research
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP 2016 Vox Sang View Researchers Basic research
Mitochondria and membrane cryoinjury in micropatterned cells: Effects of cell-cell interactions Tchir J, Acker JP 2010 Cryobiology View Researchers Basic research
Platelet immunology in China: research and clinical applications Wu G, Zhou Y, Li L, Zhong Z, Li H, Li H, Yu M, Shen W, Ni H 2017 Transfus Med Rev View Researchers Clinical research
Renin-Angiotensin System Blockade and Long-term Clinical Outcomes in Kidney Transplant Recipients: A Meta-analysis of Randomized Controlled Trials Hiremath S, Fergusson DA, Fergusson N, Bennett A, Knoll GA 2017 Am J Kidney Dis View Researchers Clinical research
Solving the dilemma of prevention of red cell alloimmunization Branch DR 2012 Immunotherapy View Researchers Other
The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression Huard CC, Tremblay CS, Magron A, Levesque G, Carreau M 2014 PNAS View Researchers Basic research
The role of inflammation in intravenous immune globulin-mediated hemolysis Pendergrast J, Willie-Ramharack K, Sampson L, Laroche V, Branch DR 2015 Transfusion View Researchers Clinical research
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH 2016 Blood View Researchers Clinical research
ResearchUnit: A different way to look at red blood cell quality Acker J 2018 Blood.ca website View Researchers Clinical research
Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia Huynh A, Arnold DM, Kelton JG, Smith JW, Horsewood P, Clare R, Guarné A, Nazy I 2018 J Thromb Haemost View Researchers Basic research
IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcgRIIA Disease-Associated Gene Variant Kozicky LK, Menzies SC, Zhao ZY, Vira T, Harnden K, Safari K, Del Bel KL, Turvey SE, Sly LM 2018 Front Immunol View Researchers Basic research
What's in a name? Patient registration errors and their threat to transfusion safety Ning S, Yan MTS, Downie H, Callum J 2018 Transfusion View Researchers New or improved product or process
Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques Scott BM, Sheffield WP 2020 Protein Sci View Researchers Basic research
Ironing out frequent blood donation Devine DV 2019 Lancet Haematol View Researchers New or improved product or process
Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype Almizraq R, Kipkeu B, Acker JP 2020 Transfusion View Researchers Basic research
An AI-Driven Predictive Modelling Framework to Analyze and Visualize Blood Product Transactional Data for Reducing Blood Products’ Discards Rad J, Cheng C, Quinn JG, Abidi S, Liwski R, Abidi SSR 2020 Artificial Intelligence in Medicine View Researchers New or improved product or process
Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate derivatives William N, Acker JP 2020 Cryobiology View Researchers Basic research
Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy Balitsky AK, Liu Y, Van der Meer PF, Heddle NM, Arnold DM 2021 Transfusion View Researchers Clinical research
SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada Saeed S, Drews SJ, Pambrun C, Yi Q-L, Osmond L, O'Brien SF 2021 Transfusion View Researchers Clinical research
Updated Understanding of Platelets in Thrombosis and Hemostasis: The Roles of Integrin PSI Domains and their Potential as Therapeutic Targets MacKeigan DT, Ni T, Shen C, Stratton TW, Ma W, Zhu G, Bhoria P, Ni H 2020 Cardiovasc Hematol Disord Drug Targets View Researchers Basic research
SARS-CoV-2 Virus-Like Particle Neutralizing Capacity in Blood Donors Depends on Serological Profile and Donor-Declared SARS-CoV-2 Vaccination History Drews SJ, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Mostafa HH 2022 Microbiol Spectr View Researchers Clinical research
National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies Holmberg JA, Henry SM, Burnouf T, Devine D, Marschner S, Boothby TC, Burger SR, Chou ST, Custer B, Blumberg N, Siegel DL, Spitalnik SL 2022 Transfusion View Researchers Benchmarking and standard setting
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia Li N, Mahamad S, Parpia S, Iorio A, Foroutan F, Heddle NM, Hsia CC, Sholzberg M, Rimmer E, Shivakumar S, Sun HL, Refaei M, Hamm C, Arnold DM 2022 J Thromb Haemost View Researchers New or improved product or process
Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex Sask KN, Thong B, Goodarzynejad N, Berry LR, Chan AKC 2022 Biointerphases View Researchers Basic research
GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach Zeng L, Brignardello-Petersen R, Hultcrantz M, Mustafa RA, Murad MH, Iorio A, Traversy G, Akl EA, Mayer M, Schünemann HJ, Guyatt GH 2022 J Clin Epidemiol View Researchers Clinical research
A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE 2014 Biomaterials View Researchers Basic research
Adhesion Molecules. Ni H 2013 Mechanisms in Hematology View Researchers Basic research
An investigation of red blood cell concentrate quality during storage in paediatric-sized polyvinylchloride bags plasticized with alternatives to di-2-ethylhexyl phthalate (DEHP) Serrano K, Levin E, Chen D, Hansen A, Turner TR, Kurach J, Reidel A, Boecker WF, Acker JP, Devine DV 2015 Vox Sang View Researchers Basic research
ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE 2013 Chem Commun View Researchers Basic research
Cell-matrix interactions of Factor IX (FIX)-engineered human mesenchymal stromal cells encapsulated in RGD-alginate vs. Fibrinogen-alginate microcapsules Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 Artif Cells Nanomed Biotechnol View Researchers Basic research
Comments on: Bernardo et al. 2016 (Blood)Working together to block alloimmunization Stowell SR 2016 Blood View Researchers Basic research
Diagnostic accuracy of IgG-specific versus polyspecific enzyme-linked immunoassays in heparin-induced thrombocytopenia: a systematic review and meta-analysis Husseinzadeh HD, Gimotty PA, Pishko AM, Buckley M, Warkentin TE, Cuker A 2017 J Thromb Haemost View Researchers Clinical research
Ebola virus VP35 blocks stress granule assembly Le Sage V, Cinti A, McCarthy S, Amorim R, Rao S, Daino GL, Tramontano E, Branch DR, Mouland AJ 2017 Virology View Researchers Basic research
Epigenetic regulation of endothelial-cell-mediated vascular repair Fraineau S, Palii CG, Allan DS, Brand M 2015 FEBS J View Researchers Other
Extended storage and glucose exhaustion are associated with apoptotic changes in platelets stored in additive solution Johnson L, Schubert P, Tan S, Devine DV, Marks DC 2015 Transfusion View Researchers Basic research
Fully automated decomposition of raman spectra into individual Pearson's type VII distributions applied to biological and biomedical samples Schulze HG, Atkins CG, Devine DV, Blades MW, Turner RF 2015 Appl Spectrosc View Researchers Basic research
How do I interpret a p value? O'Brien SF, Osmond L, Yi Q-L 2015 Transfusion View Researchers Other
Impact of ethnicity on human umbilical cord blood banking: a systematic review Akyurekli C, Chan JY, Elmoazzen H, Tay J, Allan DS 2014 Transfusion View Researchers Clinical research
Innate immunity as orchestrator of stem cell mobilization Ratajczak MZ, Kim CH, Wojakowski W, Janowska-Wieczorek A, Kucia M, Ratajczak J 2010 Leukemia View Researchers Basic research