Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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The role of inflammation in intravenous immune globulin-mediated hemolysis | Pendergrast J, Willie-Ramharack K, Sampson L, Laroche V, Branch DR | 2015 | Transfusion | View The role of inflammation in intravenous immune globulin-mediated hemolysis | Researchers | Clinical research |
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis | Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH | 2016 | Blood | View Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis | Researchers | Clinical research |
ResearchUnit: A different way to look at red blood cell quality | Acker J | 2018 | Blood.ca website | View ResearchUnit: A different way to look at red blood cell quality | Researchers | Clinical research |
Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia | Huynh A, Arnold DM, Kelton JG, Smith JW, Horsewood P, Clare R, Guarné A, Nazy I | 2018 | J Thromb Haemost | View Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia | Researchers | Basic research |
GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out | Lewis BJB, Leontyev D, Neschadim A, Blacquiere M, Branch DR | 2018 | Clin Exp Immunol | View GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out | Researchers | Basic research |
ResearchUnit: Plasma: what's in the bag? | Sheffield W, Jenkins C | 2018 | Blood.ca website | View ResearchUnit: Plasma: what's in the bag? | Researchers | Basic research |
Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques | Scott BM, Sheffield WP | 2020 | Protein Sci | View Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques | Researchers | Basic research |
Ironing out frequent blood donation | Devine DV | 2019 | Lancet Haematol | View Ironing out frequent blood donation | Researchers | New or improved product or process |
Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype | Almizraq R, Kipkeu B, Acker JP | 2020 | Transfusion | View Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype | Researchers | Basic research |
An AI-Driven Predictive Modelling Framework to Analyze and Visualize Blood Product Transactional Data for Reducing Blood Products’ Discards | Rad J, Cheng C, Quinn JG, Abidi S, Liwski R, Abidi SSR | 2020 | Artificial Intelligence in Medicine | View An AI-Driven Predictive Modelling Framework to Analyze and Visualize Blood Product Transactional Data for Reducing Blood Products’ Discards | Researchers | New or improved product or process |
Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate derivatives | William N, Acker JP | 2020 | Cryobiology | View Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate derivatives | Researchers | Basic research |
Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy | Balitsky AK, Liu Y, Van der Meer PF, Heddle NM, Arnold DM | 2021 | Transfusion | View Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy | Researchers | Clinical research |
SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada | Saeed S, Drews SJ, Pambrun C, Yi Q-L, Osmond L, O'Brien SF | 2021 | Transfusion | View SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada | Researchers | Clinical research |
Updated Understanding of Platelets in Thrombosis and Hemostasis: The Roles of Integrin PSI Domains and their Potential as Therapeutic Targets | MacKeigan DT, Ni T, Shen C, Stratton TW, Ma W, Zhu G, Bhoria P, Ni H | 2020 | Cardiovasc Hematol Disord Drug Targets | View Updated Understanding of Platelets in Thrombosis and Hemostasis: The Roles of Integrin PSI Domains and their Potential as Therapeutic Targets | Researchers | Basic research |
SARS-CoV-2 Virus-Like Particle Neutralizing Capacity in Blood Donors Depends on Serological Profile and Donor-Declared SARS-CoV-2 Vaccination History | Drews SJ, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Mostafa HH | 2022 | Microbiol Spectr | View SARS-CoV-2 Virus-Like Particle Neutralizing Capacity in Blood Donors Depends on Serological Profile and Donor-Declared SARS-CoV-2 Vaccination History | Researchers | Clinical research |
National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies | Holmberg JA, Henry SM, Burnouf T, Devine D, Marschner S, Boothby TC, Burger SR, Chou ST, Custer B, Blumberg N, Siegel DL, Spitalnik SL | 2022 | Transfusion | View National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies | Researchers | Benchmarking and standard setting |
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia | Li N, Mahamad S, Parpia S, Iorio A, Foroutan F, Heddle NM, Hsia CC, Sholzberg M, Rimmer E, Shivakumar S, Sun HL, Refaei M, Hamm C, Arnold DM | 2022 | J Thromb Haemost | View Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia | Researchers | New or improved product or process |
Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex | Sask KN, Thong B, Goodarzynejad N, Berry LR, Chan AKC | 2022 | Biointerphases | View Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex | Researchers | Basic research |
GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach | Zeng L, Brignardello-Petersen R, Hultcrantz M, Mustafa RA, Murad MH, Iorio A, Traversy G, Akl EA, Mayer M, Schünemann HJ, Guyatt GH | 2022 | J Clin Epidemiol | View GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach | Researchers | Clinical research |
A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment | Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE | 2014 | Biomaterials | View A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment | Researchers | Basic research |
Adhesion Molecules. | Ni H | 2013 | Mechanisms in Hematology | View Adhesion Molecules. | Researchers | Basic research |
An investigation of red blood cell concentrate quality during storage in paediatric-sized polyvinylchloride bags plasticized with alternatives to di-2-ethylhexyl phthalate (DEHP) | Serrano K, Levin E, Chen D, Hansen A, Turner TR, Kurach J, Reidel A, Boecker WF, Acker JP, Devine DV | 2015 | Vox Sang | View An investigation of red blood cell concentrate quality during storage in paediatric-sized polyvinylchloride bags plasticized with alternatives to di-2-ethylhexyl phthalate (DEHP) | Researchers | Basic research |
ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive | Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE | 2013 | Chem Commun | View ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive | Researchers | Basic research |
Cell-matrix interactions of Factor IX (FIX)-engineered human mesenchymal stromal cells encapsulated in RGD-alginate vs. Fibrinogen-alginate microcapsules | Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G | 2014 | Artif Cells Nanomed Biotechnol | View Cell-matrix interactions of Factor IX (FIX)-engineered human mesenchymal stromal cells encapsulated in RGD-alginate vs. Fibrinogen-alginate microcapsules | Researchers | Basic research |
Comments on: Bernardo et al. 2016 (Blood)Working together to block alloimmunization | Stowell SR | 2016 | Blood | View Comments on: Bernardo et al. 2016 (Blood)Working together to block alloimmunization | Researchers | Basic research |
Diagnostic accuracy of IgG-specific versus polyspecific enzyme-linked immunoassays in heparin-induced thrombocytopenia: a systematic review and meta-analysis | Husseinzadeh HD, Gimotty PA, Pishko AM, Buckley M, Warkentin TE, Cuker A | 2017 | J Thromb Haemost | View Diagnostic accuracy of IgG-specific versus polyspecific enzyme-linked immunoassays in heparin-induced thrombocytopenia: a systematic review and meta-analysis | Researchers | Clinical research |
Ebola virus VP35 blocks stress granule assembly | Le Sage V, Cinti A, McCarthy S, Amorim R, Rao S, Daino GL, Tramontano E, Branch DR, Mouland AJ | 2017 | Virology | View Ebola virus VP35 blocks stress granule assembly | Researchers | Basic research |
Epigenetic regulation of endothelial-cell-mediated vascular repair | Fraineau S, Palii CG, Allan DS, Brand M | 2015 | FEBS J | View Epigenetic regulation of endothelial-cell-mediated vascular repair | Researchers | Other |
Extended storage and glucose exhaustion are associated with apoptotic changes in platelets stored in additive solution | Johnson L, Schubert P, Tan S, Devine DV, Marks DC | 2015 | Transfusion | View Extended storage and glucose exhaustion are associated with apoptotic changes in platelets stored in additive solution | Researchers | Basic research |
Fully automated decomposition of raman spectra into individual Pearson's type VII distributions applied to biological and biomedical samples | Schulze HG, Atkins CG, Devine DV, Blades MW, Turner RF | 2015 | Appl Spectrosc | View Fully automated decomposition of raman spectra into individual Pearson's type VII distributions applied to biological and biomedical samples | Researchers | Basic research |
How do I interpret a p value? | O'Brien SF, Osmond L, Yi Q-L | 2015 | Transfusion | View How do I interpret a p value? | Researchers | Other |
Impact of ethnicity on human umbilical cord blood banking: a systematic review | Akyurekli C, Chan JY, Elmoazzen H, Tay J, Allan DS | 2014 | Transfusion | View Impact of ethnicity on human umbilical cord blood banking: a systematic review | Researchers | Clinical research |
Innate immunity as orchestrator of stem cell mobilization | Ratajczak MZ, Kim CH, Wojakowski W, Janowska-Wieczorek A, Kucia M, Ratajczak J | 2010 | Leukemia | View Innate immunity as orchestrator of stem cell mobilization | Researchers | Basic research |
Megakaryopoiesis and ex vivo differentiation of stem cells into megakaryocytes and platelets | Pineault N, Boisjoli GJ | 2015 | ISBT Sci Ser | View Megakaryopoiesis and ex vivo differentiation of stem cells into megakaryocytes and platelets | Researchers | Basic research |
Monoclonal versus polyclonal anti-D in the treatment of ITP | Lazarus AH | 2013 | Expert Opin Biol Ther | View Monoclonal versus polyclonal anti-D in the treatment of ITP | Researchers | Basic research |
On-chip PCR amplification of genomic and viral templates in unprocessed whole blood | Manage DP, Morrissey YC, Stickel AJ, Lauzon J, Atrazhev A, Acker JP, Pilarski LM | 2011 | Microfluid Nanofluidics | View On-chip PCR amplification of genomic and viral templates in unprocessed whole blood | Researchers | New or improved product or process |
Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin | Scott BM, Matochko WL, Gierczak RF, Bhakta V, Derda R, Sheffield WP | 2014 | PLoS One | View Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin | Researchers | Basic research |
Platelet-activating antibodies are detectable at the earliest onset of heparin-induced thrombocytopenia, with implications for the operating characteristics of the serotonin-release assay | Warkentin TE, Arnold DM, Kelton JG, Sheppard JI, Smith JW, Nazy I | 2018 | Chest | View Platelet-activating antibodies are detectable at the earliest onset of heparin-induced thrombocytopenia, with implications for the operating characteristics of the serotonin-release assay | Researchers | Clinical research |
Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016 | Vostal JG, Buehler PW, Gelderman MP, Alayash AI, Doctor A, Zimring JC, Glynn SA, Hess JR, Klein H, Acker JP, Spinella PC, D'Alessandro A, Palsson B, Raife TJ, Busch MP, McMahon TJ, Intaglietta M, Swartz HM, Dubick MA, Cardin S, Patel RP, Natanson C, Weisel JW, Muszynski JA, Norris PJ, Ness PM | 2018 | Transfusion | View Proceedings of the Food and Drug Administration's public workshop on new red blood cell product regulatory science 2016 | Researchers | New or improved product or process |
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials | Lalu MM, McIntyre L, Pugliese C, Fergusson D, Winston BW, Marshall JC, Granton J, Stewart DJ, Canadian Critical Care Trials Group | 2012 | PLoS One | View Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials | Researchers | Clinical research |
Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier | Singh S, Dubinsky-Davidchik IS, Kluger R | 2016 | Org Biomol Chem | View Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier | Researchers | Basic research |
The cell motility modulator Slit2 is a potent inhibitor of platelet function | Patel S, Huang YW, Reheman A, Pluthero FG, Chaturvedi S, Mukovozov IM, Tole S, Liu GY, Li L, Durocher Y, Ni H, Kahr WH, Robinson LA | 2012 | Circulation | View The cell motility modulator Slit2 is a potent inhibitor of platelet function | Researchers | Basic research |
Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils | Campbell IK, Miescher S, Branch DR, Mott PJ, Lazarus AH, Han D, Maraskovsky E, Zuercher AW, Neschadim A, Leontyev D, McKenzie BS, Kasermann F | 2014 | J Immunol | View Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils | Researchers | Basic research |
Vascular endothelial dysfunction in beta-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO | Stoyanova E, Trudel M, Felfly H, Lemsaddek W, Garcia D, Cloutier G | 2012 | PLoS One | View Vascular endothelial dysfunction in beta-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO | Researchers | Basic research |
Modelling the Need for New Blood Donors Following a Change in Deferral Period | Blake J | 2018 | Industrial Engineering and Operations Management I | View Modelling the Need for New Blood Donors Following a Change in Deferral Period | Researchers | Clinical research |
Assessing opportunities and challenges for establishing a national program to distribute cord blood for research | Isasi R, Mastronardi C, Golder M, Allan D, Walker M, Halpenny M, Yang L, Elmoazzen H, Chargé S | 2018 | Transfusion | View Assessing opportunities and challenges for establishing a national program to distribute cord blood for research | Researchers | Other |
45 - Alloimmune Thrombocytopenia | Kaplan C, Bertrand G, Ni H | 2019 | Platelets (Fourth Edition) | View 45 - Alloimmune Thrombocytopenia | Researchers | New or improved product or process |
Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain | Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AGM, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT | 2018 | Am J Physiol Regul Integr Comp Physiol | View Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain | Researchers | Basic research |
Evaluation of a hydrogel-based diagnostic approach for the point-of-care based detection of Neisseria gonorrhoeae | Perera S, Taheri A, Khan N, Parti R, Stefura S, Skiba P, Acker J, Martin I, Kusalik A, Dillon J-A | 2018 | Antibiotics | View Evaluation of a hydrogel-based diagnostic approach for the point-of-care based detection of Neisseria gonorrhoeae | Researchers | New or improved product or process |
Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains | Spitalnik SL, Devine DV | 2019 | Transfusion | View Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains | Researchers | Other |