Our Research Publications
Updated November 2023
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Title Sort descending | Authors | Year | Journal | Link to Article | Intended Audience | Purpose |
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A novel nanobiotherapeutic poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] with no cardiac toxicity for the resuscitation of a rat model with 90 minutes of sustained severe hemorrhagic shock with loss of 2/3 blood volume | Bian Y, Chang TM | 2015 | Artif Cells Nanomed Biotechnol | View A novel nanobiotherapeutic poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] with no cardiac toxicity for the resuscitation of a rat model with 90 minutes of sustained severe hemorrhagic shock with loss of 2/3 blood volume | Researchers | Basic research |
A novel VSV/HIV pseudotype approach for the study of HIV microbicides without requirement for level 3 biocontainment | Harrison AL, Henry S, Mahfoud R, Manis A, Albertini A, Gaudin Y, Lingwood CA, Branch DR | 2011 | Future Virol | View A novel VSV/HIV pseudotype approach for the study of HIV microbicides without requirement for level 3 biocontainment | Researchers | Basic research |
A personalized limited sampling approach to better estimate terminal half-life of FVIII concentrates | Chelle P, Iorio A, Edginton AN | 2022 | J Thromb Haemost | View A personalized limited sampling approach to better estimate terminal half-life of FVIII concentrates | Researchers | Basic research |
A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment | Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE | 2014 | Biomaterials | View A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment | Researchers | Basic research |
A phase-II sequential case-series study of all patients presenting to four plasma exchange centres with presumed relapsed/refractory thrombotic thrombocytopenic purpura treated with rituximab | Clark WF, Rock G, Barth D, Arnold DM, Webert KE, Yenson PR, Kelton JG, Li L, Foley SR, members of the Canadian Apheresis G | 2015 | Br J Haematol | View A phase-II sequential case-series study of all patients presenting to four plasma exchange centres with presumed relapsed/refractory thrombotic thrombocytopenic purpura treated with rituximab | Health care providers | Clinical research |
A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models | Sheffield WP, Eltringham-Smith LJ, Gataiance S, Bhakta V | 2014 | J Thromb Thrombolysis | View A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models | Researchers | Basic research |
A platelet cover-up | Arnold DM | 2013 | Blood | View A platelet cover-up | Researchers | Other |
A platelet viability assay (PVA) for the diagnosis of heparin-induced thrombocytopenia | Ivetic N, Arnold D, Smith J, Huynh A, Kelton J, Nazy I | 2019 | Platelets | View A platelet viability assay (PVA) for the diagnosis of heparin-induced thrombocytopenia | Researchers | Basic research |
A Portrait of Cord Blood Units Distributed for Transplantation from Canadian Blood Services’ Cord Blood Bank: First Analysis | Parmar G, Green M, Mostert K, Lawless T, Dibdin N, Weiss J, Ganz K, Petraszko T, Seftel MD, Allan DS | 2022 | Curr Oncol | View A Portrait of Cord Blood Units Distributed for Transplantation from Canadian Blood Services’ Cord Blood Bank: First Analysis | Researchers | Benchmarking and standard setting |
A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion | Qadri SM, Liu Y, Barty RL, Heddle NM, Sheffield WP | 2022 | Vox Sang | View A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion | Researchers | Clinical research |
A Primer on Biostatistics | Shih AW, Li N, Montemayor C, Heddle NM | 2022 | Practical Transfusion Medicine | View A Primer on Biostatistics | Health care providers | Benchmarking and standard setting |
A prospective multi-faceted interventional study of blood bank technologist screening of red blood cell transfusion orders: The START study | Kron AT, Collins A, Cserti-Gazdewich C, Pendergrast J, Webert K, Lieberman L, Zeller MP, Harding SR, Nahirniak S, Prokopchuk-Gauk O, Lin Y, Mendez B, Armali C, Lee C, Watson D, Arnott D, Xun F, Blain H, Panchuk H, Hughes H, Chorneyko K, Angers M, Pilutti N, Lett R, Dowsley S, Ruijs T, Cupido T, Kichinko T, Thompson T, Afshar-Ghotli Z, Callum J, University of Toronto Quality in Utilization, Education and Safety in Transfusion (QUEST) Research Program | 2021 | Transfusion | View A prospective multi-faceted interventional study of blood bank technologist screening of red blood cell transfusion orders: The START study | Health care providers | Clinical research |
A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic | Grunau B, O’Brien SF, Kirkham TL, Helmer J, Demers PA, Asamoah-Boaheng M, Drews SJ, Karim ME, Srigley JA, Sediqi S, O’Neill D, Drennan IR, Goldfarb DM | 2022 | Ann Emerg Med | View A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic | Researchers | Clinical research |
A prospective observational study of the incidence, natural history, and risk factors for intravenous immunoglobulin-mediated hemolysis | Pendergrast J, Armali C, Callum J, Cserti-Gazdewich C, Jiwajee A, Lieberman L, Lau W, Lin Y, Parmar N, Pavenski K, Riden LS, Shehata N, Willie-Ramharack K, Tomlinson G, Tong TN, Binnington B, Branch DR | 2021 | Transfusion | View A prospective observational study of the incidence, natural history, and risk factors for intravenous immunoglobulin-mediated hemolysis | Researchers | Clinical research |
A prospective study measuring the development of antibodies against platelet factor 4-heparin in healthy males after exposure to heparins | Kelton JG, Warkentin TE, Moore JC, Arnold DM, Nazi I, Arepally GM, Roach JM, Fier I | 2012 | J Thromb Haemost | View A prospective study measuring the development of antibodies against platelet factor 4-heparin in healthy males after exposure to heparins | Health care providers | Clinical research |
A push in Alberta for "pay-for-plasma" distracts from bigger questions | Cattapan A | 2020 | Policy Options | View A push in Alberta for "pay-for-plasma" distracts from bigger questions | Other | Ethical, legal and social implications research |
A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 | Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Robbins NF, Orjuela G, Jenkins C, Conrod V, Yi Q-L, O’Brien SF, Drews SJ | 2022 | Microbiol Spectr | View A Qualitative Comparison of the Abbott SARS-CoV-2 IgG II Quant Assay against Commonly Used Canadian SARS-CoV-2 Enzyme Immunoassays in Blood Donor Retention Specimens, April 2020 to March 2021 | Researchers | Benchmarking and standard setting |
A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing | Acker JP, Hansen AL, Kurach JD, Turner TR, Croteau I, Jenkins C | 2014 | Transfusion | View A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing | Blood operators | Benchmarking and standard setting |
A randomized controlled trial comparing the outcome of critically ill adults who received fresher vs. older red cells units | Lacroix J, Hébert PC, Fergusson DA, Tinmouth A, Walsh T, Stanworth S, Campbell H, Boyd J, Burrows H, Hemmatapour S, on behalf of the Canadian Critical Care Trials Group | 2016 | ISBT Sci Ser | View A randomized controlled trial comparing the outcome of critically ill adults who received fresher vs. older red cells units | Health care providers | Clinical research |
A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus | McCarthy SDS, Majchrzak-Kita B, Racine T, Kozlowski HN, Baker DP, Hoenen T, Kobinger GP, Fish EN, Branch DR | 2016 | PLoS Negl Trop Dis | View A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus | Researchers | Basic research |
A regional massive hemorrhage protocol developed through a modified Delphi technique | Callum JL, Yeh CH, Petrosoniak A, McVey MJ, Cope S, Thompson T, Chin V, Karkouti K, Nathens AB, Murto K, Beno S, Pendergrast J, McDonald A, MacDonald R, Adhikari NKJ, Alam A, Arnold D, Barratt L, Beckett A, Brenneman S, Chaudhry HR, Collins A, Harvey M, Lampron J, Margarido C, McFarlan A, Nascimento B, Owens W, Pai M, Rizoli S, Ruijs T, Skeate R, Skelton T, Sholzberg M, Syer K, Viveiros JL, Theriault J, Tinmouth A, Van Heest R, White S, Zeller M, Pavenski K | 2019 | CMAJ Open | View A regional massive hemorrhage protocol developed through a modified Delphi technique | Health care providers | Clinical research |
A Retrospective Chart Review of Transfusion Practices in the Palliative Care Unit Setting | Sirianni G, Perri G, Callum J, Gardner S, Berall A, Selby D | 2018 | Am J Hosp Palliat Care | View A Retrospective Chart Review of Transfusion Practices in the Palliative Care Unit Setting | Researchers | Clinical research |
A retrospective study of the added value of parallel titers compared with serial titers | Lin Y, Cohen R, Buckstein J, Callum J, Lieberman L | 2019 | Transfusion | View A retrospective study of the added value of parallel titers compared with serial titers | Health care providers | Clinical research |
A role for red cell clearance in antibody-mediated inhibition of erythrocyte alloimmunization? | Marjoram D, Cruz-Leal Y, Bernardo L, Lazarus AH | 2017 | ISBT Sci Ser | View A role for red cell clearance in antibody-mediated inhibition of erythrocyte alloimmunization? | Researchers | Basic research |
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination | Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y | 2022 | medRxiv | View A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination | Researchers | New or improved product or process |
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination | Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y | 2022 | Clin Transl Immunol | View A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination | Researchers | New or improved product or process |
A simple protein-based surrogate neutralization assay for SARS-CoV-2 | Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis Ii AP, Girardin RC, Rathod B, Wang J, Barrios-Rodiles M, Colwill K, McGeer A, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC | 2020 | JCI Insight | View A simple protein-based surrogate neutralization assay for SARS-CoV-2 | Researchers | New or improved product or process |
A single-institution analysis of the utility of pre-induction ejection fraction measurement in patients newly diagnosed with acute myeloid leukemia | Bryant A, Sheppard D, Sabloff M, Delbaere M, Maze R, Allan D, Atkins H, Bence-Bruckler I, Faught C, Huebsch L, Tay J, Zanke B, Bredeson C | 2015 | Leuk Lymphoma | View A single-institution analysis of the utility of pre-induction ejection fraction measurement in patients newly diagnosed with acute myeloid leukemia | Health care providers | Clinical research |
A stressful predicament for blood bankers! | Branch DR | 2020 | Transfus Med | View A stressful predicament for blood bankers! | Blood operators | Basic research |
A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial | Ypma PF, van der Meer PF, Heddle NM, van Hilten JA, Stijnen T, Middelburg RA, Hervig T, van der Bom JG, Brand A, Kerkhoffs JL | 2016 | BMJ Open | View A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial | Researchers | Clinical research |
A Survey of Patient Experience in CML: American and Canadian Perspectives | Hillis C, Flynn KE, Goldman EH, Moreira-Lucas TS, Visentini J, Dorman S, Ballinger R, Byrnes HF, De Palma A, Barbier V, Machado L, Atallah E | 2023 | Patient Prefer Adherence | View A Survey of Patient Experience in CML: American and Canadian Perspectives | Researchers | Clinical research |
A suspected septic transfusion reaction associated with posttransfusion contamination of a platelet pool by vancomycin-resistant Enterococcus faecium | Drews SJ, Lesley P, Detsky ME, Distefano L, Ilagan C, Mehta S, McGeer A, Shehata N, Skeate R, Ramirez-Arcos S | 2020 | Transfusion | View A suspected septic transfusion reaction associated with posttransfusion contamination of a platelet pool by vancomycin-resistant Enterococcus faecium | Researchers | Basic research |
A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms | Harrison AL, Olsson ML, Jones RB, Ramkumar S, Sakac D, Binnington B, Henry S, Lingwood CA, Branch DR | 2010 | Glycoconj J | View A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms | Researchers | Basic research |
A systematic evaluation of laboratory testing for drug-induced immune thrombocytopenia | Arnold DM, Kukaswadia S, Nazi I, Esmail A, Dewar L, Smith JW, Warkentin TE, Kelton JG | 2013 | J Thromb Haemost | View A systematic evaluation of laboratory testing for drug-induced immune thrombocytopenia | Health care providers | Clinical research |
A systematic review of definitions and reporting of bleeding outcome measures in haemophilia | Chai-Adisaksopha C, Hillis C, Thabane L, Iorio A | 2015 | Haemophilia | View A systematic review of definitions and reporting of bleeding outcome measures in haemophilia | Health care providers | Clinical research |
A systematic review of preclinical studies on the therapeutic potential of mesenchymal stromal cell-derived microvesicles | Akyurekli C, Le Y, Richardson RB, Fergusson D, Tay J, Allan DS | 2015 | Stem Cell Rev | View A systematic review of preclinical studies on the therapeutic potential of mesenchymal stromal cell-derived microvesicles | Health care providers | Clinical research |
A systematic review of the association between anti-?-2 glycoprotein I antibodies and APS manifestations | Jiang D, Lim W, Crowther M, Garcia D | 2021 | Blood Adv | View A systematic review of the association between anti-?-2 glycoprotein I antibodies and APS manifestations | Researchers | Clinical research |
A thermoreversible poly(choline phosphate) based universal biomembrane adhesive | Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE | 2014 | Macromol Biosci | View A thermoreversible poly(choline phosphate) based universal biomembrane adhesive | Researchers | Basic research |
A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors | Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M | 2021 | Transfusion | View A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors | Researchers | Basic research |
A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial | Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K | 2016 | Trials | View A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial | Researchers | Clinical research |
A user guide to the American Society of Hematology clinical practice guidelines | Izcovich A, Cuker A, Kunkle R, Neumann I, Panepinto J, Pai M, Seftel M, Cheung MC, Lottenberg R, Byrne M, Plovnick R, Terrell D, Holter-Chakrabarty JL, Djulbegovic B, Hicks LK, Wiercioch W, Nieuwlaat R, Schünemann HJ | 2020 | Blood Adv | View A user guide to the American Society of Hematology clinical practice guidelines | Health care providers | Benchmarking and standard setting |
AABB Committee Report: reducing transfusion-transmitted cytomegalovirus infections | AABB Clinical Transfusion Medicine Committee, Heddle NM, Boeckh M, Grossman B, Jacobson J, Kleinman S, Tobian AAR, Webert K, Wong ECC, Roback JD | 2016 | Transfusion | View AABB Committee Report: reducing transfusion-transmitted cytomegalovirus infections | Blood operators | Clinical research |
ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group | Goel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So – Osman C, Wood E, Devine DV, Spitalnik SL, the ISBT COVID-19 Working Group | 2021 | Vox Sang | View ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group | Researchers | Clinical research |
ABO blood groups influence macrophage-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes | Wolofsky KT, Ayi K, Branch DR, Hult AK, Olsson ML, Liles WC, Cserti-Gazdewich CM, Kain KC | 2012 | PLoS Pathog | View ABO blood groups influence macrophage-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes | Researchers | Basic research |
ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM | 2022 | Blood | View ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Researchers | Basic research |
ABO zygosity, but not secretor or Fc receptor status, is a significant risk factor for IVIG-associated hemolysis | Branch DR, Hellberg Å, Bruggeman CW, Storry JR, Sakac D, Blacquiere M, Tong TN, Burke-Murphy E, Binnington B, Parmar N, Riden LS, Willie K, Armali C, Aziz J, Lieberman L, Laroche V, Callum J, Lin Y, Shehata N, Pavenski K, Lau W, Hannach B, Kuijpers TW, Olsson ML, Cserti-Gazdewich C, Pendergrast J | 2018 | Blood | View ABO zygosity, but not secretor or Fc receptor status, is a significant risk factor for IVIG-associated hemolysis | Health care providers | Clinical research |
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 | Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM | 2015 | Sci Rep | View Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 | Researchers | Basic research |
Accuracy of International Classification of Diseases, 10th Revision Codes for Identifying Sepsis: A Systematic Review and Meta-Analysis | Liu B, Hadzi-Tosev M, Liu Y, Lucier KJ, Garg A, Li S, Heddle NM, Rochwerg B, Ning S | 2022 | Crit Care Explor | View Accuracy of International Classification of Diseases, 10th Revision Codes for Identifying Sepsis: A Systematic Review and Meta-Analysis | Health care providers | Clinical research |
Acellular pertussis vaccine effectiveness and waning immunity in Alberta, Canada: 2010–2015, a Canadian Immunization Research Network (CIRN) study | Bell CA, Russell ML, Drews SJ, Simmonds KA, Svenson LW, Schwartz KL, Kwong JC, Mahmud SM, Crowcroft NS | 2019 | Vaccine | View Acellular pertussis vaccine effectiveness and waning immunity in Alberta, Canada: 2010–2015, a Canadian Immunization Research Network (CIRN) study | Health care providers | Clinical research |
Acetylsalicyclic acid for the prevention and treatment of thromboembolic diseases | Webert K, Kelton J | 2016 | Aspirin and related drugs | View Acetylsalicyclic acid for the prevention and treatment of thromboembolic diseases | Health care providers | Clinical research |