Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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Severe hemolytic disease of the fetus and newborn due to allo-anti-D in a patient with a partial DEL phenotype arising from the variant allele described as RHD*148+1T (RHD*01EL.31) | Turley E, McGowan EC, Hyland CA, Schoeman EM, Flower RL, Skoll A, Delisle MF, Nelson T, Clarke G, Au N | 2018 | Transfusion | View Severe hemolytic disease of the fetus and newborn due to allo-anti-D in a patient with a partial DEL phenotype arising from the variant allele described as RHD*148+1T (RHD*01EL.31) | Researchers | Clinical research |
Age-Separated RBCs Show Changes in Oxygen Carrying Capacity and Rigidity During Hypothermic Storage | Mykhailova O, Li W, Acker J | 2019 | Probl Cryobiol Cryomed | View Age-Separated RBCs Show Changes in Oxygen Carrying Capacity and Rigidity During Hypothermic Storage | Researchers | Basic research |
Decoding the metabolic landscape of pathophysiological stress-induced cell death in anucleate red blood cells | Nemkov T, Qadri SM, Sheffield WP, D'Alessandro A | 2020 | Blood Transfus | View Decoding the metabolic landscape of pathophysiological stress-induced cell death in anucleate red blood cells | Researchers | Basic research |
Human leukocyte antigen-G upregulates immunoglobulin-like transcripts and corrects dysfunction of immune cells in immune thrombocytopenia | Li X, Sheng Z, Sun Y, Wang Y, Xu M, Zhang Z, Li H, Shao L, Zhang Y, Yu J, Ma C, Gao C, Hou M, Ni H, Peng J, Ma J, Feng Q | 2020 | Haematologica | View Human leukocyte antigen-G upregulates immunoglobulin-like transcripts and corrects dysfunction of immune cells in immune thrombocytopenia | Researchers | Basic research |
Multi-laboratory assay for harmonization of enumeration of viable CD34+ and CD45+ cells in frozen cord blood units | Fournier D, Lewin A, Simard C, Trépanier P, Néron S, Ballerini L, Codinach M, Elmoazzen H, Halpenny M, Kogler G, Liedtke S, Louis I, Molluna CA, Pineault N, Prasath A, Querol S, Saccardi R, Sutherland DR, Thérien C, Urbani S | 2020 | Cytotherapy | View Multi-laboratory assay for harmonization of enumeration of viable CD34+ and CD45+ cells in frozen cord blood units | Researchers | Benchmarking and standard setting |
Using umbilical cord blood for regenerative therapy: Proof or promise? | Allan DS | 2020 | Stem Cells | View Using umbilical cord blood for regenerative therapy: Proof or promise? | Researchers | Clinical research |
Concentré de recherche: Les dons de sang effectués avant la grossesse sont sans danger pour les mères et les bébés | Chassé M | 2020 | Blood.ca website | Researchers | Clinical research | |
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials | Lawati KA, Sharif S, Maqbali SA, Rimawi HA, Petrosoniak A, Belley-Cote EP, Sharma SV, Morgenstern J, Fernando SM, Owen JJ, Zeller M, Quinlan D, Alhazzani W, Rochwerg B | 2021 | Intensive Care Med | Researchers | Clinical research | |
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis | Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP | 2021 | Sci Rep | View Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis | Researchers | Basic research |
Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion | Leatherdale A, Parker DA, Tasneem S, Wang Y, Bihan D, Bonna A, Hamaia SW, Gross PL, Ni H, Doble BW, Lillicrap D, Farndale RW, Hayward CPM | 2021 | J Thromb Haemost | View Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion | Researchers | Basic research |
Research initiatives of blood services worldwide in response to the covid-19 pandemic | O'Brien SF, Lieshout-Krikke RW, Lewin A, Erikstrup C, Steele WR, Uzicanin S, Custer B, the Surveillance RA, Policy Sub-group of the ISBT Transfusion Transmitted Infectious Diseases Working Party | 2021 | Vox Sang | View Research initiatives of blood services worldwide in response to the covid-19 pandemic | Researchers | Clinical research |
Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism | Patel P, Patel P, Bhatt M, Braun C, Begum H, Nieuwlaat R, Khatib R, Martins CC, Zhang Y, Etxeandia-Ikobaltzeta I, Varghese J, Alturkmani H, Bahaj W, Baig M, Kehar R, Mustafa A, Ponnapureddy R, Sethi A, Thomas M, Wooldridge D, Lim W, Bates SM, Lang E, Le Gal G, Haramati LB, Kline J, Righini M, Wiercioch W, Schünemann H, Mustafa RA | 2021 | Blood Adv | View Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism | Researchers | Clinical research |
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? | Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H | 2021 | Sci Rep | View In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? | Researchers | Clinical research |
Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects | Huynh A, Arnold DM, Smith JW, Moore JC, Zhang A, Chagla Z, Harvey BJ, Stacey HD, Ang JC, Clare R, Ivetic N, Chetty VT, Bowdish DME, Miller MS, Kelton JG, Nazy I | 2021 | Viruses | View Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects | Researchers | Clinical research |
An international comparison of HIV prevalence and incidence in blood donors and general population: a BEST Collaborative study | Germain M, Grégoire Y, Custer BS, Goldman M, Bravo M, Kamel H, Davison K, Field S, van den Hurk K, van de Laar TJW, Irving DO, Jones A, Liumbruno G, Morley S, O’Brien SF, Pillonel J, Steinsvåg CT, Takanashi M, Tsuno NH, Vesga Carasa MA, Wendel S, Vassallo RR, Tiberghien P, for the BEST Collaborative | 2021 | Vox Sang | View An international comparison of HIV prevalence and incidence in blood donors and general population: a BEST Collaborative study | Researchers | Benchmarking and standard setting |
Characterizing Frailty In Myeloproliferative Neoplasms: results from the ORCHID study | Chornenki NLJ, Siegal DM, Qamar K, Woolgar S, Rangarajan S, Karampatos S, Leong DP, Hillis CM | 2022 | Leuk Res | View Characterizing Frailty In Myeloproliferative Neoplasms: results from the ORCHID study | Researchers | Clinical research |
Sensitivity of the Elecsys Nucleocapsid Assay for the Detection of Preceding SARS-CoV-2 Infections | Grunau B, Tom J, Asamoah-Boaheng M, O’Brien SF, Drews SJ, Sediqi S, Lavoie PM, Barakauskas V, Goldfarb DM | 2022 | Open Forum Infect Dis | View Sensitivity of the Elecsys Nucleocapsid Assay for the Detection of Preceding SARS-CoV-2 Infections | Researchers | Basic research |
Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency-first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository | Kumar R, Bakeer N, Dawson J, Al-Mughairy A, Stanek J, Dunn A, Male C, Chan A, Williams S | 2023 | J Thromb Haemost | View Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency-first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository | Researchers | Basic research |
Altered timing of riboflavin and ultraviolet light pathogen inactivation improves platelet in vitro quality | Schubert P, Culibrk B, Karwal S, Serrano K, Levin E, Yi Q, Thiele T, Greinacher A, Marschner S, Devine DV | 2017 | Transfusion | View Altered timing of riboflavin and ultraviolet light pathogen inactivation improves platelet in vitro quality | Researchers | New or improved product or process |
Apixaban for treatment of confirmed heparin-induced thrombocytopenia: a case report and review of literature | Ezekwudo DE, Chacko R, Gbadamosi B, Batool S, Gaikazian S, Warkentin TE, Sheppard JI, Jaiyesimi I | 2017 | Exp Hematol Oncol | View Apixaban for treatment of confirmed heparin-induced thrombocytopenia: a case report and review of literature | Researchers | Clinical research |
Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors | D'Aragon F, Dhanani S, Lamontagne F, Cook DJ, Burns K, Akhtar A, Chasse M, Frenette AJ, Keenan S, Lize JF, Kutsogiannis DJ, Kramer A, Hand LE, Arseneau E, Masse MH, Ribic C, Ball I, Baker A, Boyd G, Rochwerg B, Healey A, Hanna S, Guyatt GH, Meade MO | 2017 | BMJ Open | View Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors | Researchers | Clinical research |
Concentré de recherche: Un modèle de changement : prédiction de l'impact d'améliorations à l'échelle du système | Blake J | 2018 | Blood.ca website | View Concentré de recherche: Un modèle de changement : prédiction de l'impact d'améliorations à l'échelle du système | Researchers | Basic research |
Determination of the biological form of human cytomegalovirus DNA in the plasma of solid-organ transplant recipients | Tong Y, Pang XL, Mabilangan C, Preiksaitis JK | 2017 | J Infect Dis | View Determination of the biological form of human cytomegalovirus DNA in the plasma of solid-organ transplant recipients | Researchers | Clinical research |
Eltrombopag after allogeneic haematopoietic cell transplantation in a case of poor graft function and systematic review of the literature | Dyba J, Tinmouth A, Bredeson C, Matthews J, Allan DS | 2016 | Transfus Med | View Eltrombopag after allogeneic haematopoietic cell transplantation in a case of poor graft function and systematic review of the literature | Researchers | Clinical research |
Fibronectin maintains the balance between hemostasis and thrombosis | Wang Y, Ni H | 2016 | Cell Mol Life Sci | View Fibronectin maintains the balance between hemostasis and thrombosis | Researchers | Basic research |
Hope for the Best, but Prepare for the Worst | Blake J, Nemergut EC | 2014 | Anesth Analg | View Hope for the Best, but Prepare for the Worst | Researchers | New or improved product or process |
Impact of blood manufacturing and donor characteristics on membrane water permeability and in vitro quality parameters during hypothermic storage of red blood cells | Alshalani A, Howell A, Acker JP | 2018 | Cryobiology | View Impact of blood manufacturing and donor characteristics on membrane water permeability and in vitro quality parameters during hypothermic storage of red blood cells | Researchers | Basic research |
Innate and adaptive immunity in immune thrombocytopenia | Lazarus AH, Semple JW, Cines DB | 2013 | Semin Hematol | View Innate and adaptive immunity in immune thrombocytopenia | Researchers | Clinical research |
Laboratory management of perinatal patients with apparently "new" anti-D | Hannon J, Clarke G | 2016 | Immunohematology | View Laboratory management of perinatal patients with apparently "new" anti-D | Researchers | Basic research |
Mechanistic properties of intravenous immunoglobulin in murine immune thrombocytopenia: support for Fc?RIIB falls by the wayside | Crow AR, Lazarus AH | 2016 | Semin Hematol | View Mechanistic properties of intravenous immunoglobulin in murine immune thrombocytopenia: support for Fc?RIIB falls by the wayside | Researchers | Basic research |
O-aryl-glycoside ice recrystallization inhibitors as novel cryoprotectants: A structure-function study | Capicciotti CJ, Mancini RS, Turner TR, Koyama T, Alteen MG, Doshi M, Inada T, Acker JP, Ben RN | 2016 | ACS Omega | View O-aryl-glycoside ice recrystallization inhibitors as novel cryoprotectants: A structure-function study | Researchers | Basic research |
Rationale and design of platelet transfusions in haematopoietic stem cell transplantation: the PATH pilot study | Tay J, Allan D, Beattie S, Bredeson C, Fergusson D, Maze D, Sabloff M, Thavorn K, Tinmouth A | 2016 | BMJ Open | View Rationale and design of platelet transfusions in haematopoietic stem cell transplantation: the PATH pilot study | Researchers | Clinical research |
The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia | Arnold DM, Lauzier F, Albert M, Williamson D, Li N, Zarychanski R, Doig C, McIntyre L, Freitag A, Crowther M, Saunders L, Clarke F, Bellomo R, Qushmaq I, Lopes R, Heels-Ansdell D, Webert K, Cook D | 2017 | Res Pract Thromb Haemost | View The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia | Researchers | Clinical research |
The Ins and Outs of Hematopoietic Stem Cells: Studies to Improve Transplantation Outcomes | Marquez-Curtis LA, Turner AR, Sridharan S, Ratajczak MZ, Janowska-Wieczorek A | 2011 | Stem Cell Rev | View The Ins and Outs of Hematopoietic Stem Cells: Studies to Improve Transplantation Outcomes | Researchers | Basic research |
Value of MMA crossmatch? | Tong TN, Cserti-Gazdewich CM, Branch DR | 2016 | Transfus Med | View Value of MMA crossmatch? | Researchers | Basic research |
Peri-Operative Eltrombopag or Immune Globulin for Patients with Immune Thrombocytopaenia (The Bridging ITP Trial): Methods and Rationale | Arnold D, Jamula E, Heddle N, Cook R, Hsia C, Sholzberg M, Lin Y, Kassis J, Blostein M, Larratt L, Amini S, Schipperus M, Carruthers J, Lane S, Li N, G. Kelton J | 2019 | Thromb Haemost | View Peri-Operative Eltrombopag or Immune Globulin for Patients with Immune Thrombocytopaenia (The Bridging ITP Trial): Methods and Rationale | Researchers | Clinical research |
International survey on the impact of parasitic infections: frequency of transmission and current mitigation strategies | Leiby DA, O'Brien SF, Wendel S, Nguyen ML, Delage G, Devare SG, Hardiman A, Nakhasi HL, Sauleda S, Bloch EM, WPTTID Subgroup on Parasites | 2019 | Vox Sang | View International survey on the impact of parasitic infections: frequency of transmission and current mitigation strategies | Researchers | Clinical research |
Thermal expansion of substrate may affect adhesion of Chinese hamster fibroblasts to surfaces during freezing | Rutt T, Eskandari N, Zhurova M, Elliott JAW, McGann LE, Acker JP, Nychka JA | 2019 | Cryobiology | View Thermal expansion of substrate may affect adhesion of Chinese hamster fibroblasts to surfaces during freezing | Researchers | Basic research |
Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay | Warkentin TE, Arnold DM, Kelton JG, Sheppard J-AI, Smith JW, Nazy I | 2018 | Chest | View Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay | Researchers | Basic research |
The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses | Mendonca A, Rahman MS, Alhalawani A, Rodriguez O, Gallant RC, Ni H, Clarkin OM, Towler MR | 2019 | J Biomed Mater Res Part B Appl Biomater | View The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses | Researchers | Basic research |
International Forum on Occult hepatitis B infection and transfusion safety | Seed CR, Allain J-P, Lozano M, Laperche S, Gallian P, Gross S, Kwon S-Y, Oh EY, Kim JN, Chua SS, Lam S, Ang AL, Tsoi W-C, Hewitt PE, Davison KL, Tettmar K, O'Flaherty N, Boland F, Williams P, Pomeroy L, Wendel S, Fachini R, Scuracchio P, Carminato P, Fearon M, O'Brien SF, Delage G, Kiely P, Hoad V, Matsubayashi K, Satake M, Taira R, Stramer SL, Sauleda S, Bes M, Piron M, El Ekiaby M, Vermeulen M, Levi?nik Stezinar S, Nograšek P, Jarvis LM, Petrik J, Charlewood R, Flanagan P, Grabarczyk P, Kopacz A, ??towska M, Seifried E, Schmidt M | 2019 | Vox Sang | View International Forum on Occult hepatitis B infection and transfusion safety | Researchers | Benchmarking and standard setting |
Platelet physiology and immunology: pathogenesis and treatment of classical and non-classical fetal and neonatal alloimmune thrombocytopenia | Chen ZY, Oswald BE, Sullivan JA, Dahmani FZ, Pasman Y, Liu Z, Chen P, Ni H | 2019 | Ann Blood | View Platelet physiology and immunology: pathogenesis and treatment of classical and non-classical fetal and neonatal alloimmune thrombocytopenia | Researchers | Basic research |
The systematic use of evidence-based methodologies and technologies enhances shared decision-making in the 2018 International Consensus Conference on Patient Blood Management | Van Remoortel H, Aranko K, Mueller MM, De Buck E, Devine D, Folléa G, Meybohm P, Tiberghien P, Wood EM, Vandekerckhove P, Seifried E | 2020 | Vox Sang | View The systematic use of evidence-based methodologies and technologies enhances shared decision-making in the 2018 International Consensus Conference on Patient Blood Management | Researchers | Benchmarking and standard setting |
Age-Specific SARS-CoV-2 Infection Fatality and Case Identification Fraction in Ontario, Canada | Fisman DN, Drews SJ, Tuite AR, O’Brien SF | 2020 | medRxiv | View Age-Specific SARS-CoV-2 Infection Fatality and Case Identification Fraction in Ontario, Canada | Researchers | Clinical research |
Characterizing the ability of an ice recrystallization inhibitor to improve platelet cryopreservation | Waters L, Ben R, Acker JP, Padula MP, Marks DC, Johnson L | 2020 | Cryobiology | View Characterizing the ability of an ice recrystallization inhibitor to improve platelet cryopreservation | Researchers | New or improved product or process |
Crosstalk Between Platelets and Microbial Pathogens | Li C, Li J, Ni H | 2020 | Front Immunol | View Crosstalk Between Platelets and Microbial Pathogens | Researchers | Basic research |
Evidence for sustained mucosal and systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients | Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yun YF, Marin LG, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, J.McGeer A, Gommerman JL, Gingras A-C | 2020 | medRxiv | View Evidence for sustained mucosal and systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients | Researchers | Basic research |
Safety and efficacy of self-administered romiplostim in patients with immune thrombocytopenia: Results of an integrated database of five clinical trials | Kuter DJ, Arnold DM, Rodeghiero F, Janssens A, Selleslag D, Bird R, Newland A, Mayer J, Wang K, Olie R | 2020 | Am J Hematol | View Safety and efficacy of self-administered romiplostim in patients with immune thrombocytopenia: Results of an integrated database of five clinical trials | Researchers | Clinical research |
Psychometric Evaluation of ITP Life Quality Index (ILQI) in a Global Survey of Patients with Immune Thrombocytopenia | Viana R, D'Alessio D, Grant L, Cooper N, Arnold D, Morgan M, Provan D, Cuker A, Hill QA, Tomiyama Y, Ghanima W | 2021 | Adv Ther | View Psychometric Evaluation of ITP Life Quality Index (ILQI) in a Global Survey of Patients with Immune Thrombocytopenia | Researchers | Clinical research |
Risk of transfusion-transmitted Babesia microti in Canada | O'Brien SF, Drews SJ, Yi Q-L, Bloch EM, Ogden NH, Koffi JK, Lindsay LR, Gregoire Y, Delage G | 2021 | Transfusion | View Risk of transfusion-transmitted Babesia microti in Canada | Researchers | Benchmarking and standard setting |