Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Quality and Safety of Blood Products Ramirez-Arcos S, Marks DC, Acker JP, Sheffield WP 2016 J Blood Transfus View Researchers Other
ResearchUnit: Older blood as good as new: no harmful effects of storage time before transfusion Heddle N 2016 Blood.ca website View Other Other
Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data Jordan A, Chen D, Yi QL, Kanias T, Gladwin MT, Acker JP 2016 Vox Sang View Researchers Basic research
CMV Seronegative, irradiated, and washed blood components Prokopchuk-Gauk O, Solh Z 2016 Clinical Guide to Transfusion View Health care providers Other
Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers Wang A, Kluger R 2016 Biochemistry View Researchers Basic research
Peculiarities of studying the effects of pathogen reduction technologies on platelets Osman A, Hitzler WE, Provost P 2016 Proteomics Clin Appl View Researchers Basic research
Platelet Transfusion Practices in the Intensive Care Unit: Data from a Large Transfusion Registry Ning S, Barty R, Liu Y, Heddle NM, Rochwerg B, Arnold DM 2016 Chest View Health care providers Clinical research
Raman spectroscopy as a novel tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB 2016 Analyst View Researchers New or improved product or process
Stability of coagulation protein activities in single units or pools of cryoprecipitate during storage at 20–24°C for up to 24 h Sheffield WP, Bhakta V, Jenkins C 2016 Vox Sang View Blood operators New or improved product or process
Targeting FcRs to treat antibody-dependent autoimmunity Yu X, Lazarus AH 2016 Autoimmun Rev View Researchers Other
Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process Gunz A, McNally J, Whyte H, O'Hearn K, Foster J, Parker M, Dhanani S 2016 J Pediatr Intensive Care View Researchers Clinical research
Extracellular vesicles in transfusion-related immunomodulation and the role of blood component manufacturing Almizraq RJ, Seghatchian J, Acker JP 2016 Transfusion and Apheresis Science View Researchers Basic research
Interpretation of pretransfusion testing in obstetrical patients who have received antepartum Rh immunoglobulin prophylaxis Szkotak AJ, Lunty B, Nahirniak S, Clarke G 2016 Vox Sang View Health care providers Clinical research
Physical characterization of hematopoietic stem cells using multidirectional label-free light scatterings Shahin H, Gupta M, Janowska-Wieczorek A, Rozmus W, Tsui YY 2016 Optics Express View Researchers Basic research
ResearchUnit: Hijacked: the role of platelets in dengue virus infection revealed Pryzdial EL 2016 Blood.ca website View Other Other
Resolving variable maternal D typing using serology and genotyping in selected prenatal patients Clarke G, Hannon J, Berardi P, Barr G, Cote J, Fallis R, Alport T, Lane D, Petraszko T, Ochoa G, Goldman M 2016 Transfusion View Health care providers New or improved product or process
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions Singh S, Kluger R 2016 Biochemistry View Researchers Basic research
The nonhemostatic immune functions of platelets Kapur R, Semple JW 2016 Semin Hematol View Researchers Basic research
Thrombocytopenic syndromes in pregnancy Yan M, Malinowski AK, Shehata N 2016 Obstet Med View Health care providers Clinical research
A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K 2016 Trials View Researchers Clinical research
Platelet concentrate functionality assessed by thromboelastography or rotational thromboelastometry Arbaeen AF, Serrano K, Levin E, Devine DV 2016 Transfusion View Researchers Basic research
Quality assessment of established and emerging blood components for transfusion Acker J, Marks DC, Sheffield W 2016 J Blood Transfus View Blood operators Benchmarking and standard setting
Assessing the Rationale and Effectiveness of Frozen Plasma Transfusions: An Evidence-based Review Tinmouth A 2016 Hematol Oncol Clin North Am View Researchers Clinical research
CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fc? Receptor– and Complement Receptor 3–Dependent Mechanisms Amash A, Wang L, Wang Y, Bhakta V, Fairn GD, Hou M, Peng J, Sheffield WP, Lazarus AH 2016 J Immunol View Researchers Basic research
Coagulation factor concentrates Poon MC 2016 Clinical Guide to Transfusion View Health care providers Other
Heterogeneity in Studies of Mesenchymal Stromal Cells to Treat or Prevent Graft-versus-Host Disease: A Scoping Review of the Evidence Rizk M, Monaghan M, Shorr R, Kekre N, Bredeson CN, Allan DS 2016 Biol Blood Marrow Transplant View Researchers Basic research
Platelet transfusion reactions do not occur more often in recipients transfused with apheresis versus buffy coat platelet concentrates Cserti-Gazdewich C, Escorcia A, Pendergrast J, Lieberman L, Skeate R, Lin Y, Callum J 2016 Transfusion View Researchers Clinical research
A new diagnosis of Addison's disease with a twist Alhabib M, McAssey K, Parker MJ 2016 J Endocrinol Diabetes View Health care providers Clinical research
A randomized controlled trial comparing the outcome of critically ill adults who received fresher vs. older red cells units Lacroix J, Hébert PC, Fergusson DA, Tinmouth A, Walsh T, Stanworth S, Campbell H, Boyd J, Burrows H, Hemmatapour S, on behalf of the Canadian Critical Care Trials Group 2016 ISBT Sci Ser View Health care providers Clinical research
Changing the 30-min Rule in Canada: The Effect of Room Temperature on Bacterial Growth in Red Blood Cells Ramirez-Arcos S, Kou Y, Ducas É, Thibault L 2016 Transfus Med Hemother View Blood operators Benchmarking and standard setting
Difficulties in establishing the diagnosis of immune thrombocytopenia: An agreement study Salib M, Clayden R, Clare R, Wang G, Warkentin TE, Crowther MA, Lim W, Nazi I, Kelton JG, Arnold DM 2016 Am J Hematol View Researchers Clinical research
Effect of short-term vs. long-term blood storage on mortality after transfusion Heddle NM, Cook RJ, Arnold DM, Liu Y, Barty R, Crowther MA, Devereaux P, Hirsh J, Warkentin TE, Webert KE 2016 N Engl J Med View Health care providers Clinical research
Mouse Models for Immune-Mediated Platelet Destruction or Immune Thrombocytopenia (ITP) Neschadim A, Branch DR 2016 Curr Protoc Immunol View Researchers Basic research
The Ottawa criteria for the appropriate use of perioperative blood transfusions in liver resection using the RAND/UCLA appropriateness method. Bennett S, Fergusson D, Tinmouth A, McIsaac D, Pawlik T, Hebert P, Mcintyre L, Karanicolas P, Barkun J, Turgeon-Fournier A 2016 Can J Surg View Health care providers Clinical research
AABB Committee Report: reducing transfusion-transmitted cytomegalovirus infections AABB Clinical Transfusion Medicine Committee, Heddle NM, Boeckh M, Grossman B, Jacobson J, Kleinman S, Tobian AAR, Webert K, Wong ECC, Roback JD 2016 Transfusion View Blood operators Clinical research
Best practices in the differential diagnosis and reporting of acute transfusion reactions Heddle N, Hillis C, Shih A 2016 Internat J Clin Transfus Med View Health care providers Clinical research
Fetal and neonatal alloimmune thrombocytopenia Zdravic D, Yougbare I, Vadasz B, Li C, Marshall AH, Chen P, Kjeldsen-Kragh J, Ni H 2016 Semin Fetal Neonatal Med View Researchers Basic research
Immune Globulin Products Nahirniak S, Lazarus A 2016 Clinical Guide to Transfusion View Health care providers Other
Neurological PRESentations in Sickle Cell Patients Are Not Always Stroke: A Review of Posterior Reversible Encephalopathy Syndrome in Sickle Cell Disease Solh Z, Taccone MS, Marin S, Athale U, Breakey VR 2016 Pediatr Blood Cancer View Health care providers Clinical research
An evaluation of overall effectiveness and treatment satisfaction with intravenous immunoglobulin among patients with immune thrombocytopenia Sholapur NS, Hamilton K, Butler L, Heddle NM, Arnold DM 2016 Transfusion View Researchers Clinical research
High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis Mithoowani S, Gregory-Miller K, Goy J, Miller MC, Wang G, Noroozi N, Kelton JG, Arnold DM 2016 Lancet Haematol View Researchers Clinical research
Molecular immunohaematology round table discussions at the AABB Annual Meeting, Anaheim 2015 Flegel WA, Castilho L, Heaton WA, Keller MA, Klapper EB, Lane WJ, Pirenne F, Shehata N, Stack G, St-Louis M, Tormey CA, Wagner FF, Waxman DA, Denomme GA 2016 Transfusion View Health care providers Clinical research
Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions Hume HA, Ddungu H, Angom R, Baluku H, Kajumbula H, Kyeyune-Byabazaire D, Orem J, Ramirez-Arcos S, Tobian AA 2016 Transfusion View Researchers Basic research
ResearchUnit: United we stand, divided we fall: using monoclonal antibody combinations to improve drug effectiveness Lazarus A 2016 Blood.ca website View Other Other
Stability of Thawed Apheresis Fresh-Frozen Plasma Stored for up to 120 Hours at 1° C to 6° C Sheffield WP, Bhakta V, Yi Q-L, Jenkins C 2016 J Blood Transfus View Researchers Basic research
Temperature stability of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] in the form of a solution or in the lyophilized form during storage at -80°C, 4°C, 25°C and 37°C or pasteurization at 70°C Bian Y, Guo C, Chang T 2016 Artif Cells Nanomed Biotechnol View Researchers Basic research
Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, Hebert PC 2016 Cochrane Database Syst Rev View Health care providers Clinical research
Validation of administrative database codes for acute kidney injury in kidney transplant recipients Molnar AO, van Walraven C, McArthur E, Fergusson D, Garg AX, Knoll G 2016 Can J Kidney Health Dis View Regulators New or improved product or process
A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus McCarthy SDS, Majchrzak-Kita B, Racine T, Kozlowski HN, Baker DP, Hoenen T, Kobinger GP, Fish EN, Branch DR 2016 PLoS Negl Trop Dis View Researchers Basic research
Deformability based sorting of red blood cells improves diagnostic sensitivity for malaria caused by Plasmodium falciparum Guo Q, Duffy SP, Matthews K, Deng X, Santoso AT, Islamzada E, Ma H 2016 Lab Chip View Researchers New or improved product or process