Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Riboflavin and ultraviolet light treatment potentiates vasodilator-stimulated phosphoprotein Ser-239 phosphorylation in platelet concentrates during storage Schubert P, Culibrk B, Coupland D, Scammell K, Gyongyossy-Issa M, Devine DV 2012 Transfusion View Researchers Basic research
The efficacy and safety of topical tranexamic acid: A systematic review and meta-analysis Montroy J, Hutton B, Moodley P, Fergusson NA, Cheng W, Tinmouth A, Lavallee LT, Fergusson DA, Breau RH 2018 Transfus Med Rev View Researchers Clinical research
The promise of organ and tissue preservation to transform medicine Giwa S, Lewis JK, Alvarez L, Langer R, Roth AE, Church GM, Markmann JF, Sachs DH, Chandraker A, Wertheim JA, Rothblatt M, Boyden E, Eidbo E, Lee A, Pomahac B, Brandacher, Weinstock D, Elliott G, Nelson D, Acker JP, Uygun K, Schmalz B, Weegman B, Tocchio A, Fahy GM 2017 Nat Biotechnol View Researchers New or improved product or process
Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution Kwan DH, Constantinescu I, Chapanian R, Higgins MA, Kotzler MP, Samain E, Boraston AB, Kizhakkedathu JN, Withers SG 2015 J Am Chem Soc View Researchers New or improved product or process
Unraveling the IVIG mystique Branch DR 2013 Transfusion View Researchers Other
Psychometric properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther M, Iorio A 2018 BMJ Open View Researchers Clinical research
Antiplatelet antibody-induced thrombocytopenia does not correlate with megakaryocyte abnormalities in murine immune thrombocytopenia Guo L, Kapur R, Aslam R, Hunt K, Hou Y, Zufferey A, Speck ER, Rondina MT, Lazarus AH, Ni H, Semple JW 2018 Scand J Immunol View Researchers Basic research
Biocompatibility and toxicity of novel iron chelator Starch-Deferoxamine (S-DFO) compared to zinc oxide nanoparticles to zebrafish embryo: An oxidative stress based apoptosis, physicochemical and neurological study profile Nasrallah GK, Salem R, Da'as S, Al-Jamal OLA, Scott M, Mustafa I 2019 Neurotoxicol Teratol View Researchers Basic research
Modelling the Need for New Blood Donors Following a Change in Deferral Period Blake J 2019 Industrial Engineering and Operations Management View Researchers New or improved product or process
The use of IVIg in fetal and neonatal alloimmune thrombocytopenia— Principles and mechanisms Wabnitz H, Khan R, Lazarus AH 2020 Transfus Apher Sci View Researchers Clinical research
Blood donation and the global COVID-19 pandemic: areas for social science research Haw J, Holloway K, Masser B, Merz E-M, Thrope R 2020 Vox Sang View Researchers New or improved product or process
Mouse Models of Rheumatoid Arthritis for Studies on Immunopathogenesis and Preclinical Testing of Fc Receptor-Targeting Biologics Lewis BJB, Branch DR 2020 Pharmacology View Researchers Basic research
Quality of evidence-based guidelines for platelet transfusion and use: A systematic review Al-Riyami AZ, Jug R, La Rocca U, Keshavarz H, Landry D, Shehata N, Stanworth SJ, Nahirniak S 2021 Transfusion View Researchers Benchmarking and standard setting
Themed issue – focusing on donor assessment, motivation and vigilance O’Brien SF, Ullum H, Seed CR 2021 Vox Sang View Researchers New or improved product or process
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes Sun H, Yang M, Poon M-C, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S 2021 Haemophilia View Researchers Clinical research
Challenging the 30-min rule for thawed plasma Ramirez-Arcos S, Howell A, Bearne J, Bhakta V, Bower L, Cardigan R, Girard M, Kou Y, McDonald C, Nolin M-È, Sawicka D, Sheffield W 2021 Vox Sang View Researchers Benchmarking and standard setting
How do I think about blood donor eligibility criteria for medical conditions? Goldman M 2021 Transfusion View Researchers Benchmarking and standard setting
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y 2022 medRxiv View Researchers New or improved product or process
ResearchUnit: A proposed mechanism for vaccine-induced thrombotic thrombocytopenia Batarfi K 2021 Blood.ca website View Researchers Clinical research
The Effect of Sex-Mismatched Red Blood Cell Transfusion on Endothelial Cell Activation in Critically Ill Patients Alshalani A, van Manen L, Boshuizen M, van Bruggen R, Acker JP, Juffermans NP 2022 Transfus Med Hemother View Researchers Clinical research
A thermoreversible poly(choline phosphate) based universal biomembrane adhesive Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE 2014 Macromol Biosci View Researchers Basic research
Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice Liu J, Santhanakrishnan M, Natarajan P, Gibb DR, Eisenbarth SC, Tormey CA, Siddon AJ, Stowell SR, Branch DR, Hendrickson JE 2016 Blood View Researchers Basic research
Bacterial survival and distribution during buffy coat platelet production Taha M, Kalab M, Yi QL, Maurer E, Jenkins C, Schubert P, Ramirez-Arcos S 2016 Vox Sang View Researchers New or improved product or process
Chloride and other electrolyte concentrations in commonly available 5% albumin products Lai AT, Zeller MP, Millen T, Kavsak P, Szczeklik W, Elahie A, Alhazzani W, D'Aragon F, Jaeschke R, Lamontagne F, Karachi T, Cook D, Meade M, Rochwerg B 2018 Crit Care Med View Researchers Clinical research
Concentré de recherche: La présence de résidus de plasma favorise l'adhérence des bactéries à la paroi des poches utilisées pour les concentrés de plaquettes Ramirez-Arcos S 2017 Blood.ca website View Researchers Basic research
Development and testing of a stepwise thaw and dilute protocol for cryopreserved umbilical cord blood units Pasha R, Elmoazzen H, Pineault N 2017 Transfusion View Researchers New or improved product or process
Enhanced Nitrite Reductase Activity and Its Correlation with Oxygen Affinity in Hemoglobin Bis-Tetramers Wang A, Kluger R 2016 Biochemistry View Researchers Basic research
Fluorous Analogue of Chloramine-T: Preparation, X-ray Structure Determination, and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis Dzandzi JPK, Beckford Vera DR, Genady AR, Albu SA, Eltringham-Smith LJ, Capretta A, Sheffield WP, Valliant JF 2015 J Org Chem View Researchers Basic research
Herpesviruses enhance fibrin clot lysis Gershom ES, Vanden Hoek AL, Meixner SC, Sutherland MR, Pryzdial EL 2012 Thromb Haemost View Researchers Basic research
Immunoglobulin G Fc glycans are not essential for antibody-mediated immune suppression to murine erythrocytes Marjoram D, Cruz-Leal Y, Bernardo L, Le NPL, Crispin M, Yu X, Uchikawa M, Lazarus AH 2017 Blood View Researchers Basic research
In-Gel Technology for PCR Genotyping and Pathogen Detection Atrazhev A, Manage DP, Stickel AJ, Crabtree HJ, Pilarski LM, Acker JP 2010 Anal Chem View Researchers New or improved product or process
Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M 2012 Mol Cell Biol View Researchers Basic research
Novel evidence that pituitary gonadotropins directly stimulate human leukemic cells-studies of myeloid cell lines and primary patient AML and CML cells Abdelbaset-Ismail A, Borkowska S, Janowska-Wieczorek A, Tonn T, Rodriguez C, Moniuszko M, Bolkun L, Koloczko J, Eljaszewicz A, Ratajczak J, Ratajczak MZ, Kucia M 2015 Oncotarget View Researchers Basic research
Peculiarities of studying the effects of pathogen reduction technologies on platelets Osman A, Hitzler WE, Provost P 2016 Proteomics Clin Appl View Researchers Basic research
Prevention of hemolytic disease of the fetus and newborn: what have we learned from animal models? Cruz-Leal Y, Marjoram D, Lazarus AH 2017 Curr Opin Hematol View Researchers Basic research
Raman spectroscopy as a novel tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB 2016 Analyst View Researchers New or improved product or process
Targeting FcRs to treat antibody-dependent autoimmunity Yu X, Lazarus AH 2016 Autoimmun Rev View Researchers Other
The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review Bennett S, Baker LK, Martel G, Shorr R, Pawlik TM, Tinmouth A, McIsaac DI, Hébert PC, Karanicolas PJ, McIntyre L, Turgeon AF, Barkun J, Fergusson D 2017 HPB View Researchers Clinical research
The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis Kosan C, Rashkovan M, Ross J, Schaffer AM, Saba I, Lemsaddek W, Trudel M, Moroy T 2014 Am J Blood Res View Researchers Basic research
Transfusion requirements in cardiac surgery III (TRICS III): study design of a randomized controlled trial Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD 2018 J Cardiothorac Vasc Anesth View Researchers Clinical research
Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates Alabdullatif M, Atreya CD, Ramirez-Arcos S 2018 Transfusion View Researchers New or improved product or process
Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions Alshalani A, Li W, Juffermans NP, Seghatchian J, Acker JP 2019 Transfus Apher Sci View Researchers Basic research
Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV 2019 Transfusion View Researchers New or improved product or process
Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 Crowcroft NS, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Mahmud SM, Kwong JC 2019 Vaccine View Researchers Clinical research
ABO blood group and COVID-19: a review on behalf of the ISBT COVID-19 working group Goel R, Bloch EM, Pirenne F, Al-Riyami AZ, Crowe E, Dau L, Land K, Townsend M, Jecko T, Rahimi-Levene N, Patidar G, Josephson CD, Arora S, Vermeulen M, Vrielink H, Montemayor C, Oreh A, Hindawi S, van den Berg K, Serrano K, So – Osman C, Wood E, Devine DV, Spitalnik SL, the ISBT COVID-19 Working Group 2021 Vox Sang View Researchers Clinical research
COVID-19 Case-Age Distribution: Correction for Differential Testing by Age Fisman D, Greer A, Hillmer M, O'Brien S, Drews SJ, Tuite A 2020 medRxiv View Researchers Clinical research
Transitioning to Full Field Digital Mammography in Nova Scotia: Using Interrupted Time Series Methods to Study the Impact of Technology Change on Mammography Volumes Brydon M, Kephart G, Payne JI, Blake J 2020 J Med Imaging Radiat Sci View Researchers New or improved product or process
Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study Kuter DJ, Rogers KA, Boxer MA, Choi M, Agajanian R, Arnold DM, Broome CM, Field JJ, Murakhovskaya I, Numerof R, Tong S 2022 Am J Hematol View Researchers Clinical research
An intron c.149-2632T>A change in RHD is associated with aberrant transcription and very weak D phenotype Floch A, Vege S, Berardi P, Hannon J, Ochoa-Garay G, Lomas-Francis C, Westhoff CM 2022 Transfusion View Researchers Clinical research
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP 2022 Blood Adv View Researchers Clinical research