Our Research Publications
Updated August 2024
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Title | Authors | Year Sort ascending | Journal | Link to Article | Intended Audience | Purpose |
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Donor criteria for men who have sex with men: a Canadian perspective | Goldman M, Lapierre D, Lemay L, Devine D, Sher G | 2014 | Transfusion | View Donor criteria for men who have sex with men: a Canadian perspective | Blood operators | Benchmarking and standard setting |
Management of infants born with severe neonatal alloimmune thrombocytopenia: the role of platelet transfusions and intravenous immunoglobulin | Bakchoul T, Bassler D, Heckmann M, Thiele T, Kiefel V, Gross I, Arnold DM, Ditomasso J, Smith JW, Paes B, Greinacher A | 2014 | Transfusion | View Management of infants born with severe neonatal alloimmune thrombocytopenia: the role of platelet transfusions and intravenous immunoglobulin | Health care providers | Clinical research |
Relaxin receptor antagonist AT-001 synergizes with docetaxel in androgen-independent prostate xenografts | Neschadim A, Pritzker LB, Pritzker KP, Branch DR, Summerlee AJ, Trachtenberg J, Silvertown JD | 2014 | Endocr Relat Cancer | View Relaxin receptor antagonist AT-001 synergizes with docetaxel in androgen-independent prostate xenografts | Researchers | Basic research |
The Fanconi Anemia Group C Protein Interacts with Uncoordinated 5A and Delays Apoptosis | Huang F, Ben Aissa M, Magron A, Huard CC, Godin C, Levesque G, Carreau M | 2014 | PLoS One | View The Fanconi Anemia Group C Protein Interacts with Uncoordinated 5A and Delays Apoptosis | Researchers | Basic research |
A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment | Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE | 2014 | Biomaterials | View A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment | Researchers | Basic research |
Cell-matrix interactions of Factor IX (FIX)-engineered human mesenchymal stromal cells encapsulated in RGD-alginate vs. Fibrinogen-alginate microcapsules | Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G | 2014 | Artif Cells Nanomed Biotechnol | View Cell-matrix interactions of Factor IX (FIX)-engineered human mesenchymal stromal cells encapsulated in RGD-alginate vs. Fibrinogen-alginate microcapsules | Researchers | Basic research |
Medium conditioned with mesenchymal stromal cell-derived osteoblasts improves the expansion and engraftment properties of cord blood progenitors | Dumont N, Boyer L, Emond H, Saltik BC, Pasha R, Bazin R, Mantovani D, Roy DC, Pineault N | 2014 | Exp Hematol | View Medium conditioned with mesenchymal stromal cell-derived osteoblasts improves the expansion and engraftment properties of cord blood progenitors | Researchers | Basic research |
Molecular immunohematology: red cell antigen genotyping | Goldman M | 2014 | Blood.ca website | View Molecular immunohematology: red cell antigen genotyping | Health care providers | Clinical research |
Older patients with myeloma derive similar benefit from autologous transplantation | Sharma M, Zhang MJ, Zhong X, Abidi MH, Akpek G, Bacher U, Callander NS, Dispenzieri A, Freytes CO, Fung HC, Gale RP, Gasparetto C, Gibson J, Holmberg LA, Kindwall-Keller TL, Klumpp TR, Krishnan AY, Landau HJ, Lazarus HM, Lonial S, Maiolino A, Marks DI, Mehta P, Mikhael Med JR, Nishihori T, Olsson R, Ramanathan M, Roy V, Savani BN, Schouten HC, Scott E, Tay J, To LB, Vesole DH, Vogl DT, Hari P | 2014 | Biol Blood Marrow Transplant | View Older patients with myeloma derive similar benefit from autologous transplantation | Health care providers | Clinical research |
Peripheral blood monocyte-derived chemokine blockade prevents murine antibody-mediated transfusion-related acute lung injury (TRALI) | McKenzie CG, Kim M, Singh TK, Milev Y, Freedman J, Semple JW | 2014 | Blood | View Peripheral blood monocyte-derived chemokine blockade prevents murine antibody-mediated transfusion-related acute lung injury (TRALI) | Researchers | Basic research |
Platelet Utilization: A Canadian Blood Services Research and Development Symposium | Webert KE, Alam AQ, Chargé SB, Sheffield WP | 2014 | Transfus Med Rev | View Platelet Utilization: A Canadian Blood Services Research and Development Symposium | Health care providers | Other |
Antibody specific for the glycophorin A complex mediates intravenous immune globulin-resistant anemia in a murine model | Chen X, Ghaffar H, Jen CC, Lazarus AH | 2014 | Transfusion | View Antibody specific for the glycophorin A complex mediates intravenous immune globulin-resistant anemia in a murine model | Researchers | Basic research |
Hyperosmolar therapy in severe traumatic brain injury: a survey of emergency physicians from a large Canadian province | Berger Pelletier E, Emond M, Lauzier F, Savard M, Turgeon AF | 2014 | PLoS One | View Hyperosmolar therapy in severe traumatic brain injury: a survey of emergency physicians from a large Canadian province | Health care providers | Other |
The effect of timing of gamma-irradiation on hemolysis and potassium release in leukoreduced red cell concentrates stored in SAGM | Serrano K, Chen D, Hansen AL, Levin E, Turner TR, Kurach JDR, Acker JP, Devine DV | 2014 | Vox Sang | View The effect of timing of gamma-irradiation on hemolysis and potassium release in leukoreduced red cell concentrates stored in SAGM | Researchers | New or improved product or process |
Two-stage, in silico deconvolution of the lymphocyte compartment of the peripheral whole blood transcriptome in the context of acute kidney allograft rejection | Shannon CP, Balshaw R, Ng RT, Wilson-McManus JE, Keown P, McMaster R, McManus BM, Landsberg D, Isbel NM, Knoll G, Tebbutt SJ | 2014 | PLoS One | View Two-stage, in silico deconvolution of the lymphocyte compartment of the peripheral whole blood transcriptome in the context of acute kidney allograft rejection | Researchers | Basic research |
Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior | Burgess A, Dubey S, Yeung S, Hough O, Eterman N, Aubert I, Hynynen K | 2014 | Radiology | View Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior | Researchers | Basic research |
ResearchUnit: Protecting our life blood: iron deficiency in Canadian blood donors | Goldman M | 2014 | Blood.ca website | View ResearchUnit: Protecting our life blood: iron deficiency in Canadian blood donors | Other | Other |
The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression | Huard CC, Tremblay CS, Magron A, Levesque G, Carreau M | 2014 | PNAS | View The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression | Researchers | Basic research |
Adhesion of anaerobic bacteria to platelet containers | Kumaran D, Kalab M, Rood IGH, de Korte D, Ramirez-Arcos S | 2014 | Vox Sang | View Adhesion of anaerobic bacteria to platelet containers | Blood operators | Basic research |
External validation of a risk assessment model for venous thromboembolism in the hospitalised acutely-ill medical patient (VTE-VALOURR) | Mahan CE, Liu Y, Turpie AG, Vu JT, Heddle N, Cook RJ, Dairkee U, Spyropoulos AC | 2014 | Thromb Haemost | View External validation of a risk assessment model for venous thromboembolism in the hospitalised acutely-ill medical patient (VTE-VALOURR) | Health care providers | Clinical research |
Impact of ethnicity on human umbilical cord blood banking: a systematic review | Akyurekli C, Chan JY, Elmoazzen H, Tay J, Allan DS | 2014 | Transfusion | View Impact of ethnicity on human umbilical cord blood banking: a systematic review | Researchers | Clinical research |
Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin | Scott BM, Matochko WL, Gierczak RF, Bhakta V, Derda R, Sheffield WP | 2014 | PLoS One | View Phage Display of the Serpin Alpha-1 Proteinase Inhibitor Randomized at Consecutive Residues in the Reactive Centre Loop and Biopanned with or without Thrombin | Researchers | Basic research |
Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils | Campbell IK, Miescher S, Branch DR, Mott PJ, Lazarus AH, Han D, Maraskovsky E, Zuercher AW, Neschadim A, Leontyev D, McKenzie BS, Kasermann F | 2014 | J Immunol | View Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils | Researchers | Basic research |
Transfusion-related acute lung injury after transfusion of pooled immune globulin: a case report | Quest GR, Gaal H, Clarke G, Nahirniak S | 2014 | Transfusion | View Transfusion-related acute lung injury after transfusion of pooled immune globulin: a case report | Health care providers | Clinical research |
Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia | Guo L, Yang L, Speck ER, Aslam R, Kim M, McKenzie CGJ, Lazarus AH, Ni H, Hou M, Freedman J, Semple JW | 2014 | Blood | View Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia | Researchers | Basic research |
Characterization of the growth dynamics and biofilm formation of Staphylococcus epidermidis strains isolated from contaminated platelet units | Ali H, Greco-Stewart VS, Jacobs MR, Yomtovian RA, Rood IG, de Korte D, Ramirez-Arcos S | 2014 | J Med Microbiol | View Characterization of the growth dynamics and biofilm formation of Staphylococcus epidermidis strains isolated from contaminated platelet units | Blood operators | Basic research |
Growth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression | Vassen L, Beauchemin H, Lemsaddek W, Krongold J, Trudel M, Moroy T | 2014 | PLoS One | View Growth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression | Researchers | Basic research |
Polymeric Nanoparticle-Mediated Silencing of CD44 Receptor in CD34+ Acute Myeloid Leukemia Cells | Gul-Uluda H, Valencia-Serna J, Kucharski C, Marquez-Curtis LA, Jiang X, Larratt L, Janowska-Wieczorek A, Uluda H | 2014 | Leukemia Res | View Polymeric Nanoparticle-Mediated Silencing of CD44 Receptor in CD34+ Acute Myeloid Leukemia Cells | Researchers | Basic research |
RhD Specific Antibodies Are Not Detectable in HLA-DRB1(*)1501 Mice Challenged with Human RhD Positive Erythrocytes | Bernardo L, Denomme GA, Shah K, Lazarus AH | 2014 | Adv Hematol | View RhD Specific Antibodies Are Not Detectable in HLA-DRB1(*)1501 Mice Challenged with Human RhD Positive Erythrocytes | Researchers | Basic research |
Severe platelet desialylation in a patient with glycoprotein Ib/IX antibody-mediated immune thrombocytopenia and fatal pulmonary hemorrhage | Li J, Callum JL, Lin Y, Zhou Y, Zhu G, Ni H | 2014 | Haematologica | View Severe platelet desialylation in a patient with glycoprotein Ib/IX antibody-mediated immune thrombocytopenia and fatal pulmonary hemorrhage | Researchers | Clinical research |
The effects of lysine analogs during pelvic surgery: a systematic review and meta-analysis | Breau RH, Kokolo MB, Punjani N, Cagiannos I, Beck A, Niznick N, Buenaventura C, Cowan J, Knoll G, Momoli F, Morash C, Ruzicka M, Schachkina S, Tinmouth A, Xie HY, Fergusson DA | 2014 | Transfus Med Rev | View The effects of lysine analogs during pelvic surgery: a systematic review and meta-analysis | Health care providers | Clinical research |
A method to measure permeability of red blood cell membrane to water and solutes using intrinsic fluorescence | Zhurova M, Olivieri A, Holt A, Acker JP | 2014 | Clin Chim Acta | View A method to measure permeability of red blood cell membrane to water and solutes using intrinsic fluorescence | Researchers | Basic research |
Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells | Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G | 2014 | Artif Cells Nanomed Biotechnol | View Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells | Researchers | Basic research |
Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers | Wang A, Kluger R | 2014 | Biochemistry | View Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers | Researchers | Basic research |
Quality of red blood cells washed using an automated cell processor with and without irradiation | Hansen AL, Turner TR, Yi QL, Acker JP | 2014 | Transfusion | View Quality of red blood cells washed using an automated cell processor with and without irradiation | Researchers | New or improved product or process |
ResearchUnit: Red cell irradiation - time for a change? | Serrano K | 2014 | Blood.ca website | View ResearchUnit: Red cell irradiation - time for a change? | Other | Other |
TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage | Prudova A, Serrano K, Eckhard U, Fortelny N, Devine DV, Overall CM | 2014 | Blood | View TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage | Researchers | Basic research |
The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice | Eltringham-Smith LJ, Lei X, Reheman A, Lambourne MD, Pryzdial EL, Ni H, Sheffield WP | 2014 | Transfusion | View The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice | Researchers | Basic research |
The size-dependent efficacy and biocompatibility of hyperbranched polyglycerol in peritoneal dialysis | Du C, Mendelson AA, Guan Q, Chapanian R, Chafeeva I, da Roza G, Kizhakkedathu JN | 2014 | Biomaterials | View The size-dependent efficacy and biocompatibility of hyperbranched polyglycerol in peritoneal dialysis | Researchers | Basic research |
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium | Jimenez-Diaz MB, Ebert D, Salinas Y, Pradhan A, Lehane AM, Myrand-Lapierre ME, O'Loughlin KG, Shackleford DM, Justino de Almeida M, Carrillo AK, Clark JA, Dennis AS, Diep J, Deng X, Duffy S, Endsley AN, Fedewa G, Guiguemde WA, Gomez MG, Holbrook G, Horst J, Kim CC, Liu J, Lee MC, Matheny A, Martinez MS, Miller G, Rodriguez-Alejandre A, Sanz L, Sigal M, Spillman NJ, Stein PD, Wang Z, Zhu F, Waterson D, Knapp S, Shelat A, Avery VM, Fidock DA, Gamo FJ, Charman SA, Mirsalis JC, Ma H, Ferrer S, Kirk K, Angulo-Barturen I, Kyle DE, DeRisi JL, Floyd DM, Guy RK | 2014 | PNAS | View (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium | Researchers | Basic research |
A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models | Sheffield WP, Eltringham-Smith LJ, Gataiance S, Bhakta V | 2014 | J Thromb Thrombolysis | View A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models | Researchers | Basic research |
Cytokine profiles in mouse models of experimental immune thrombocytopenia reveal a lack of inflammation and differences in response to intravenous immunoglobulin depending on the mouse strain | Leontyev D, Neschadim A, Branch DR | 2014 | Transfusion | View Cytokine profiles in mouse models of experimental immune thrombocytopenia reveal a lack of inflammation and differences in response to intravenous immunoglobulin depending on the mouse strain | Researchers | Basic research |
Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis | Chasse M, English S, McIntyre L, Knoll G, Shehata N, Forster A, Wilson K, van Walraven C, Tinmouth A, Fergusson D | 2014 | Syst Rev | View Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis | Researchers | Clinical research |
How safe is safe enough, who decides and how? From a zero-risk paradigm to risk-based decision making | Menitove JE, Leach Bennett J, Tomasulo P, Katz LM | 2014 | Transfusion | View How safe is safe enough, who decides and how? From a zero-risk paradigm to risk-based decision making | Blood operators | Other |
Opinion: 'Family veto' dilemma and organ donation | Toews M, Caulfield T | 2014 | Edmonton Journal | View Opinion: 'Family veto' dilemma and organ donation | Other | Other |
Phenotype matching for sickle cell patients: a review and recommendations for transfusion practice | Skeate R, Goldman M | 2014 | Blood.ca website | View Phenotype matching for sickle cell patients: a review and recommendations for transfusion practice | Health care providers | Other |
Antibody-Mediated Immune Suppression of Erythrocyte Alloimmunization Can Occur Independently from Red Cell Clearance or Epitope Masking in a Murine Model | Yu H, Stowell SR, Bernardo L, Hendrickson JE, Zimring JC, Amash A, Uchikawa M, Lazarus AH | 2014 | J Immunol | View Antibody-Mediated Immune Suppression of Erythrocyte Alloimmunization Can Occur Independently from Red Cell Clearance or Epitope Masking in a Murine Model | Researchers | Basic research |
Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol | Lalu MM, Moher D, Marshall J, Fergusson D, Mei SH, Macleod M, Griffin G, Turgeon AF, Rudnicki M, Fishman J, Avey MT, Skidmore B, Grimshaw JM, Stewart DJ, Singh K, McIntyre L | 2014 | Syst Rev | View Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol | Researchers | Clinical research |
gT-S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo | Sheffield WP, Lambourne MD, Eltringham-Smith LJ, Bhakta V, Arnold DM, Crowther MA | 2014 | J Thromb Haemost | View gT-S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo | Researchers | Basic research |
Low pertussis toxin antibody levels in two regional cohorts of Canadian pregnant women | Bigham M, Konrad S, Van Buynder P, Van Buynder J, Isaac-Renton J, ElSherif M, Halperin SA | 2014 | Vaccine | View Low pertussis toxin antibody levels in two regional cohorts of Canadian pregnant women | Health care providers | Clinical research |