Our Research Publications
Updated August 2024
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Title | Authors | Year Sort ascending | Journal | Link to Article | Intended Audience | Purpose |
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Immunoglobulin utilization in Canada: a comparative analysis of provincial guidelines and a scoping review of the literature | Harmon M, Riazi K, Callum J, Arnold DM, Barty R, Sidhu D, Heddle NM, MacLeod L, Li N | 2023 | Allergy Asthma Clin Immunol | View Immunoglobulin utilization in Canada: a comparative analysis of provincial guidelines and a scoping review of the literature | Health care providers | Benchmarking and standard setting |
Plasma traité au solvant-détergent (Octaplasma) | Ning S, Blais-Normandin I, Tordon B, Mack J, Webert K | 2023 | Blood.ca website | View Plasma traité au solvant-détergent (Octaplasma) | Health care providers | Benchmarking and standard setting |
Warm autoimmune hemolytic anemia: new insights and hypotheses | Branch DR | 2023 | Curr Opin Hematol | View Warm autoimmune hemolytic anemia: new insights and hypotheses | Researchers | Clinical research |
Airway Adiporon Reduces Edema in a Rat Model of Prolonged Cold Ischemia and Normothermic Ex Situ Lung Perfusion | Himmat S, Ma IJ, Wang X, Forgie K, Hatami S, da Silva GMA, Acker JP, Dyck JR, Freed D, Nagendran J | 2023 | JHLT Open | View Airway Adiporon Reduces Edema in a Rat Model of Prolonged Cold Ischemia and Normothermic Ex Situ Lung Perfusion | Researchers | Basic research |
Comparison of automated solid phase versus manual saline indirect antiglobulin test methodology for non-ABO antibody titration: Implications for perinatal antibody monitoring | Niu S, Vetsch M, Beaudin L, Bodnar M, Clarke G | 2023 | Transfusion | View Comparison of automated solid phase versus manual saline indirect antiglobulin test methodology for non-ABO antibody titration: Implications for perinatal antibody monitoring | Researchers | Clinical research |
Proof of concept for detection of staphylococcal enterotoxins in platelet concentrates as a novel safety mitigation strategy | Chi SI, Yousuf B, Paredes C, Bearne J, McDonald C, Ramirez-Arcos S | 2023 | Vox Sang | View Proof of concept for detection of staphylococcal enterotoxins in platelet concentrates as a novel safety mitigation strategy | Researchers | New or improved product or process |
The von Willebrand factor-binding aptamer rondaptivon pegol as a treatment for severe and nonsevere hemophilia A | Ay C, Kovacevic KD, Kraemmer D, Schoergenhofer C, Gelbenegger G, Firbas C, Quehenberger P, Jilma-Stohlawetz P, Gilbert JC, Zhu S, Beliveau M, Koenig F, Iorio A, Jilma B, Derhaschnig U, Pabinger I | 2023 | Blood | View The von Willebrand factor-binding aptamer rondaptivon pegol as a treatment for severe and nonsevere hemophilia A | Health care providers | Clinical research |
Data for assessing red blood cell deformability from microscopy images using deep learning | Lamoureux ES, Islamzada E, Wiens MVJ, Matthews K, Duffy SP, Ma H | 2023 | Data Brief | View Data for assessing red blood cell deformability from microscopy images using deep learning | Researchers | New or improved product or process |
Summary of adverse transfusion reactions 2018-2023 | Yan M | 2023 | Blood.ca website | View Summary of adverse transfusion reactions 2018-2023 | Blood operators | Benchmarking and standard setting |
Hämolytische Erkrankung des Neugeborenen (Morbus haemolyticus neonatorum; MHN): ABO-Unverträglichkeit | International Collaboration for Transfusion Medicine Guidelines | 2023 | ICTMG.org | View Hämolytische Erkrankung des Neugeborenen (Morbus haemolyticus neonatorum; MHN): ABO-Unverträglichkeit | General public | Other |
Assessment of stored red blood cells through lab-on-a-chip technologies for precision transfusion medicine | Isiksacan Z, D’Alessandro A, Wolf SM, McKenna DH, Tessier SN, Kucukal E, Gokaltun AA, William N, Sandlin RD, Bischof J, Mohandas N, Busch MP, Elbuken C, Gurkan UA, Toner M, Acker JP, Yarmush ML, Usta OB | 2023 | Proceedings of the National Academy of Sciences | View Assessment of stored red blood cells through lab-on-a-chip technologies for precision transfusion medicine | Researchers | Basic research |
Sickle cell disease and the need for blood: Barriers to donation for African, Caribbean, and Black young adults in Canada | Haw J, Walrond J, Jayachandran J, Dordunoo D, Eche-Ameh H, Muwhen U, Phiri P, Rastogi J, Tinga B | 2023 | Transfusion | View Sickle cell disease and the need for blood: Barriers to donation for African, Caribbean, and Black young adults in Canada | Researchers | Ethical, legal & social implications research |
Modeling unrelated blood stem cell donor recruitment using simulated registrant cohorts: Assessment of human leukocyte antigen matching across ethnicity groups | Blake JT, Parmar G, Ganz K, Seftel MD, Allan DS | 2023 | Transfusion | View Modeling unrelated blood stem cell donor recruitment using simulated registrant cohorts: Assessment of human leukocyte antigen matching across ethnicity groups | Health care providers | New or improved product or process |
Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses | Kassardjian A, Sun E, Sookhoo J, Muthuraman K, Boligan KF, Kucharska I, Rujas E, Jetha A, Branch DR, Babiuk S, Barber B, Julien JP | 2023 | Cell Rep | View Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses | Researchers | Basic research |
Towards the crux of sex-dependent variability in red cell concentrates | William N, Osmani R, Acker JP | 2023 | Transfus Apher Sci | View Towards the crux of sex-dependent variability in red cell concentrates | Researchers | Basic research |
The impact of biological age of red blood cell on in vitro endothelial activation markers | Alshalani A, Beuger BM, Tuip-de Boer AM, van Bruggen R, Acker JP, Juffermans NP | 2023 | Front Physiol | View The impact of biological age of red blood cell on in vitro endothelial activation markers | Researchers | Basic research |
The importance of iron for whole blood donors: a Canadian perspective | Khandelwal A, Pambrun C, Goldman M | 2023 | Blood.ca website | View The importance of iron for whole blood donors: a Canadian perspective | Health care providers | Benchmarking and standard setting |
Chapitre 14. Aphérèse thérapeutique | Oliver M, Patriquin C | 2023 | Guide de la pratique transfusionnelle | View Chapitre 14. Aphérèse thérapeutique | Health care providers | Benchmarking and standard setting |
Extracellular vesicles: effectors of transfusion-related acute lung injury | Kuebler WM, William N, Post M, Acker JP, McVey MJ | 2023 | Am J Physiol Lung Cell | View Extracellular vesicles: effectors of transfusion-related acute lung injury | Researchers | Clinical research |
Reconsidering sickle cell trait testing of red blood cell units allocated to children with sickle cell disease | Hajjaj OI, Cserti-Gazdewich C, Dumevska L, Hanna M, Lau W, Lieberman L | 2023 | Transfusion | View Reconsidering sickle cell trait testing of red blood cell units allocated to children with sickle cell disease | Health care providers | Clinical research |
How do I provide rare red cells to patients? | Laureano M, Clarke G, Yan MTS | 2023 | Transfusion | View How do I provide rare red cells to patients? | Health care providers | Benchmarking and standard setting |
Unique features of vaccine-induced immune thrombotic thrombocytopenia; a new anti-platelet factor 4 antibody-mediated disorder | Venier LM, Clerici B, Bissola AL, Modi D, Jevtic SD, Radford M, Mahamad S, Nazy I, Arnold DM | 2023 | Int J Hematol | View Unique features of vaccine-induced immune thrombotic thrombocytopenia; a new anti-platelet factor 4 antibody-mediated disorder | Researchers | Clinical research |
Surveillance Report 2022 | O'Brien S | 2023 | Blood.ca website | View Surveillance Report 2022 | Blood operators | Benchmarking and standard setting |
La maladie hémolytique du nouveau-né (immunisation antirhésus et anticorps non ABO) | International Collaboration for Transfusion Medicine Guidelines | 2023 | ICTMG.org | View La maladie hémolytique du nouveau-né (immunisation antirhésus et anticorps non ABO) | General public | Other |
Barriers and enablers to and strategies for pro-moting plasma donation: overarching protocol for three systematic reviews | Etherington C, Palumbo A, Holloway K, Meyer S, Labrecque M, Rubini K, Shorr R, Welch V, Gibson E, Foster T, Haw J, Vesnaver E, Maharshi MT, O'Brien S, MacPherson P, Dogba J, Steed T, Goldman M, Presseau J | 2023 | PsyArXiv | View Barriers and enablers to and strategies for pro-moting plasma donation: overarching protocol for three systematic reviews | Researchers | MSM research |
Significant rosettes observed in monocyte monolayer assay due to complement-binding antibodies | Sandhu G, Lipman T, Bodnar M, Bienz MN, Branch DR | 2023 | Transfusion | View Significant rosettes observed in monocyte monolayer assay due to complement-binding antibodies | Researchers | Basic research |
Cost-effectiveness of Fibrinogen Concentrate vs Cryoprecipitate for Treating Acquired Hypofibrinogenemia in Bleeding Adult Cardiac Surgical Patients | Abrahamyan L, Tomlinson G, Callum J, Carcone S, Grewal D, Bartoszko J, Krahn M, Karkouti K | 2023 | JAMA Surg | View Cost-effectiveness of Fibrinogen Concentrate vs Cryoprecipitate for Treating Acquired Hypofibrinogenemia in Bleeding Adult Cardiac Surgical Patients | Health care providers | Clinical research |
Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice | Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP | 2023 | Sci Rep | View Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice | Researchers | Basic research |
Supplemental information Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses | Kassardjian A, Sun E, Sookhoo J, Muthuraman K, Boligan KF, Kucharska I, Rujas E, Jetha A, Branch DR, Babiuk S, Barber B, Julien J-P | 2023 | Cell Rep | View Supplemental information Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses | Researchers | Basic research |
Exploring the increasing need for plasma collection: Perspectives of voluntary nonremunerated donors on payment for plasma in Canada | Holloway K | 2023 | Transfus Med | View Exploring the increasing need for plasma collection: Perspectives of voluntary nonremunerated donors on payment for plasma in Canada | Blood operators | Ethical, legal & social implications research |
Evolving the gay, bisexual and other men who have sex with men time-based deferral to sexual risk screening for all donors: The contribution of Canadian research programmes | Caffrey N, O'Brien SF, Walsh GM, Haw J, Goldman M | 2023 | Vox Sang | View Evolving the gay, bisexual and other men who have sex with men time-based deferral to sexual risk screening for all donors: The contribution of Canadian research programmes | Researchers | MSM epidemiology research |
Cultured CD71+ erythroid cells modulate the host immune response | Alshalani A, Beuger BM, van Bruggen R, Acker JP, Juffermans NP | 2023 | Transfus Med | View Cultured CD71+ erythroid cells modulate the host immune response | Researchers | Basic research |
Importance du fer chez les donneurs de sang total : la perspective canadienne | Khandelwal A, Pambrun C, Goldman M | 2023 | Blood.ca website | View Importance du fer chez les donneurs de sang total : la perspective canadienne | Health care providers | Benchmarking and standard setting |
The Effect of the COVID-19 Pandemic on Unrelated Allogeneic Hematopoietic Donor Collections and Safety | Parmar G, Allan DS, Morris G, Dibdin N, Ganz K, Mostert K, Paulson K, Petraszko T, Stevens N, Seftel MD | 2023 | Curr Oncol | View The Effect of the COVID-19 Pandemic on Unrelated Allogeneic Hematopoietic Donor Collections and Safety | Health care providers | Clinical research |
Engineered Compounds to Control Ice Nucleation and Recrystallization | William N, Mangan S, Ben RN, Acker JP | 2023 | Ann Rev Biomed Eng | View Engineered Compounds to Control Ice Nucleation and Recrystallization | Researchers | New or improved product or process |
The under-appreciated world of the serpin family of serine proteinase inhibitors | Bouton M-C, Geiger M, Sheffield WP, Irving JA, Lomas DA, Song S, Satyanarayanan RS, Zhang L, McFadden G, Lucas AR | 2023 | EMBO Mol Med | View The under-appreciated world of the serpin family of serine proteinase inhibitors | Researchers | Basic research |
Diminished Neutralization Capacity of SARS-CoV-2 Omicron BA.1 in Donor Plasma Collected from January to March 2021 | Lin Y-CJ, Evans DH, Robbins NF, Orjuela G, Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Yi Q-L, O’Brien SF, Drews SJ | 2023 | Microbiol Spectr | View Diminished Neutralization Capacity of SARS-CoV-2 Omicron BA.1 in Donor Plasma Collected from January to March 2021 | Researchers | Clinical research |
Risk of variant Creutzfeldt–Jakob disease in a simulated cohort of Canadian blood donors | Pozzo di Borgo A, Germain M, O'Brien SF, Delage G, Renaud C, Lewin A | 2023 | Vox Sang | View Risk of variant Creutzfeldt–Jakob disease in a simulated cohort of Canadian blood donors | Researchers | Clinical research |
Do Children With an Allergic Transfusion Reaction Require Premedication or All Blood Products? | Bahabri A, Barty R, Li N, Liu Y, Kovalova T, Chan AKC | 2023 | J Pediatr Hematol Oncol | View Do Children With an Allergic Transfusion Reaction Require Premedication or All Blood Products? | Health care providers | Clinical research |
How do we forecast tomorrow's transfusion? Applying social science approaches to meet tomorrow's transfusion needs: Blood donors and donation | Haw J, Holloway K, Goldman M | 2023 | Transfus Clin Biol | View How do we forecast tomorrow's transfusion? Applying social science approaches to meet tomorrow's transfusion needs: Blood donors and donation | Researchers | Ethical, legal & social implications research |
Antigen copy number and antibody dose can determine the outcome of erythrocyte alloimmunization inducing either antibody-mediated immune suppression or enhancement in a murine model | Wabnitz H, Cruz-Leal Y, Lazarus AH | 2023 | Transfusion | View Antigen copy number and antibody dose can determine the outcome of erythrocyte alloimmunization inducing either antibody-mediated immune suppression or enhancement in a murine model | Researchers | Basic research |
La maladie hémolytique du nouveau-né (incompatibilité ABO) | International Collaboration for Transfusion Medicine Guidelines | 2023 | ICTMG.org | View La maladie hémolytique du nouveau-né (incompatibilité ABO) | General public | Other |
Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression | Li J, Karakas D, Xue F, Chen Y, Zhu G, Yucel YH, MacParland SA, Zhang H, Semple JW, Freedman J, Shi Q, Ni H | 2023 | Research | View Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression | Researchers | Basic research |
Transfusion Camp Rwanda: A prospective feasibility study evaluating the delivery of Transfusion Camp to a multidisciplinary group of postgraduate medical trainees in Rwanda | Hagumimana J, Skelton T, Pendergrast J, Nizeyimana F, Masaisa F, Kanyamuhunga A, Gashaija C, Chargé S, Kapitany C, Morgan M, Meirovich H, Lin Y | 2023 | Transfusion | View Transfusion Camp Rwanda: A prospective feasibility study evaluating the delivery of Transfusion Camp to a multidisciplinary group of postgraduate medical trainees in Rwanda | Health care providers | Education research |
Taking lessons from nature to improve cell therapy cryopreservation | Acker J, William N, Coatham M | 2023 | Cell Gene Ther Insights | View Taking lessons from nature to improve cell therapy cryopreservation | Researchers | Basic research |
Molecular Screening of Blood Donors for Babesia in Tyrol, Austria | Bloch EM, Siller A, Tonnetti L, Drews SJ, Spencer BR, Hedges D, Mergenthal T, Weber-Schehl M, Astl M, Patel EU, Gaber M, Schennach H | 2023 | Transfus Med Hemother | View Molecular Screening of Blood Donors for Babesia in Tyrol, Austria | Researchers | Clinical research |
Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S | Huynh A, Arnold DM, Michael JV, Clare R, Smith JW, Daka M, Ianosi-Irimie M, McKenzie SE, Kelton JG, Nazy I | 2023 | Blood Adv | View Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S | Researchers | Clinical research |
Donor sex, pre-donation hemoglobin, and manufacturing affect CD71+ cells in red cell concentrates | Li W, William N, Acker JP | 2023 | Transfusion | View Donor sex, pre-donation hemoglobin, and manufacturing affect CD71+ cells in red cell concentrates | Researchers | Basic research |
The high prevalence of occult hepatitis B infections among the partners of chronically infected HBV blood donors emphasizes the potential residual risk to blood safety | Ye X, Li T, Yu B, Zeng J, Shi Y, Xie H, Branch DR, Loriamini M, Li B, Chen L | 2023 | J Med Virol | View The high prevalence of occult hepatitis B infections among the partners of chronically infected HBV blood donors emphasizes the potential residual risk to blood safety | Blood operators | Clinical research |
HIV Pre-Exposure Prophylaxis, Blood Donor Deferral, Occult Infection, and Risk of HIV Transmission by Transfusion: A Fine Balance Between Evidence-Based Donor Selection Criteria and Transfusion Safety | Leblanc J-F, Custer B, Van de Laar T, Drews SJ, Germain M, Lewin A | 2023 | Transfus Med Rev | View HIV Pre-Exposure Prophylaxis, Blood Donor Deferral, Occult Infection, and Risk of HIV Transmission by Transfusion: A Fine Balance Between Evidence-Based Donor Selection Criteria and Transfusion Safety | Researchers | Clinical research |