Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Complications of a severe autoimmune hemolytic anemia crisis: transfusional iron overload and gangrenous cholecystitis Menchetti I, Lin Y, Cserti-Gazdewich C, Goldstein J, Law C, Lazarus A, Callum JL 2018 Transfusion View Researchers Clinical research
Cluster-randomized trials in transfusion medicine Sirotich E, Barty R, Li N, Arnold DM 2020 Transfusion View Researchers Clinical research
Clinical and laboratory predictors of fetal and neonatal alloimmune thrombocytopenia Matusiak K, Patriquin CJ, Deniz S, Dzaja N, Smith JW, Wang G, Nazy I, Kelton JG, Arnold DM 2022 Transfusion View Researchers Clinical research
Severe fetal anemia caused by anti-Jra: Burst forming unit-erythroid colony formation inhibition assay suggesting possible erythroid suppression mechanism Tran A, Yan MTS, Branch DR, Blacquiere M, Pineault N, Pasha R, Clarke G 2023 Transfusion View Researchers Clinical research
Biofilm-forming skin microflora bacteria are resistant to the bactericidal action of disinfectants used during blood donation Taha M, Kalab M, Yi QL, Landry C, Greco-Stewart V, Brassinga AK, Sifri CD, Ramirez-Arcos S 2014 Transfusion View Blood operators New or improved product or process
Hemolytic anemia due to passenger lymphocyte syndrome in solid malignancy patients treated with allogeneic natural killer cell products Skeate R, Singh C, Cooley S, Geller M, Northouse J, Welbig J, Slungaard A, Miller J, McKenna D 2013 Transfusion View Health care providers Clinical research
Incidence of gammopathies in long-term plasmapheresis donors at Canadian Blood Services Palmer DS, Scalia V, O'Toole J, Welch C, Yi Q, Goldman M 2015 Transfusion View Health care providers Clinical research
Management of infants born with severe neonatal alloimmune thrombocytopenia: the role of platelet transfusions and intravenous immunoglobulin Bakchoul T, Bassler D, Heckmann M, Thiele T, Kiefel V, Gross I, Arnold DM, Ditomasso J, Smith JW, Paes B, Greinacher A 2014 Transfusion View Health care providers Clinical research
Mitigation of the threat posed to transfusion by donors traveling to Zika-affected areas: a Canadian risk-based approach Germain M, Delage G, O'Brien SF, Grégoire Y, Fearon M, Devine D 2017 Transfusion View Blood operators Clinical research
New RHCE variant alleles encoding the D– – phenotype Ochoa-Garay G, Moulds JM, Cote J, Kresie L, Garaizar A, Goldman M, Wynn P 2013 Transfusion View Health care providers Clinical research
Pathogen inactivation treatment of plasma and platelet concentrates and their predicted functionality in massive transfusion protocols Arbaeen AF, Schubert P, Serrano K, Carter CJ, Culibrk B, Devine DV 2017 Transfusion View Researchers Basic research
Transfusion of antibody-opsonized red blood cells results in a shift in the immune response from the red blood cell to the antibody in a murine model Brinc D, Le-Tien H, Crow AR, Semple JW, Freedman J, Lazarus AH 2010 Transfusion View Researchers Basic research
Human red blood cell stroma: an alternative to traditional allogeneic adsorption methods Wilson EM, Branch DR 2019 Transfusion View Researchers Basic research
Variations in hemoglobin measurement and eligibility criteria across blood donation services are associated with differing low-hemoglobin deferral rates: a BEST Collaborative study Zalpuri S, Romeijn B, Allara E, Goldman M, Kamel H, Gorlin J, Vassallo R, Grégoire Y, Goto N, Flanagan P, Speedy J, Buser A, Kutner JM, Magnussen K, Castrén J, Culler L, Sussmann H, Prinsze FJ, Belanger K, Compernolle V, Tiberghien P, Cardenas JM, Gandhi MJ, West KA, Lee CK, James S, Wells D, Sutor LJ, Wendel S, Coleman M, Seltsam A, Roden K, Steele WR, Bohonek M, Alcantara R, Di Angelantonio E, van den Hurk K, BEST Collaborative 2020 Transfusion View Health care providers Clinical research
Transfusion of blood components containing ABO-incompatible plasma does not lead to higher mortality in civilian trauma patients Seheult JN, Dunbar NM, Hess JR, Tuott EE, Bahmanyar M, Campbell J, Fontaine M, Khan J, Ko A, Mi J, Murphy MF, Nykoluk T, Poisson J, Raval JS, Shih A, Sperry JL, Staves J, Wong M, Yan MTS, Ziman A, Yazer MH, Biomedical Excellence for Safer Transfusion (BEST) Collaborative 2020 Transfusion View Health care providers Clinical research
The timing of gamma irradiation and its effect on cell-free and microvesicle-bound hemoglobin. The BEST collaborative study William N, Bicahlo B, Hansen A, de Korte D, Acker JP, Biomedical Excellence for Safer Transfusion Collaborative 2022 Transfusion View Researchers Basic research
Necrotizing enterocolitis and mortality after transfusion of ABO non-identical blood Parvizian MK, Barty R, Heddle NM, Li N, McDougall T, Mukerji A, Fusch C, Solh Z 2021 Transfusion View Researchers Clinical research
An international survey on the role of the hospital transfusion committee Yazer MH, Lozano M, Fung M, Kutner J, Murphy MF, Oveland Apelseth T, Poglod R, Selleng K, Tinmouth A, Wendel S, Yahalom V, on behalf of the BEST Collaborative 2017 Transfusion View Health care providers New or improved product or process
Current practices in perioperative blood management for patients undergoing liver resection: a survey of surgeons and anesthesiologists Bennett S, Ayoub A, Tran A, English S, Tinmouth A, McIsaac DI, Fergusson D, Martel G 2018 Transfusion View Health care providers Clinical research
How do I interpret a confidence interval? O'Brien SF, Yi QL 2016 Transfusion View Researchers Other
Storage of red blood cells affects membrane composition, microvesiculation, and in vitro quality Almizraq R, Tchir JD, Holovati JL, Acker JP 2013 Transfusion View Researchers Basic research
The first case of severe acute hemolytic transfusion reaction caused by anti-Sc2 Lemay A-S, Tong TN, Branch DR, Huang M, Sumner C, Oldfield L, Hawes J, Cserti-Gazdewich CM, Lau W 2018 Transfusion View Researchers Clinical research
A case series of inactivated Japanese encephalitis virus vaccination associated with positive West Nile virus blood donor screening nucleic acid tests Drews SJ, Makowski K, Wood H, Dimitrova K, Yan MTS, Young D, Skeate R, Ng M, Hawes G, Fearon M, Bigham M 2020 Transfusion View Health care providers Clinical research
Eluates from DAT-positive patients with or without hemolysis after high-dose IVIG yield predominantly IgG isoagglutinins of IgG2 subclass Yung GP, Seebach JD, Baerenzung N, Pendergrast J, Cserti-Gazdewich C, Branch DR 2019 Transfusion View Health care providers Clinical research
A crosswalk tabular review on methods and outcomes from randomized clinical trials using pathogen reduced platelets Rebulla P, Garban F, van der Meer PF, Heddle NM, McCullough J 2020 Transfusion View Researchers Clinical research
2-HG inhibits necroptosis by stimulating DNMT1-dependent hypermethylation of the RIP3 promoter Yang Z, Jiang B, Wang Y, Ni H, Zhang J, Xia J, Shi M, Hung L, Ruan J, Mak T, Li Q, Han J 2017 Cell Rep View Researchers Basic research
A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory Yudin J, Heddle NM 2014 Lab Med View Health care providers Clinical research
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV 2014 Sci Rep View Researchers Basic research
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model Ren J, Ding X, Trudel M, Greer JJ, MacLean JE 2017 Sci Rep View Researchers Basic research
Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP 2023 Sci Rep View Researchers Basic research
IVIG regulates the survival of human but not mouse neutrophils Schneider C, Wicki S, Graeter S, Timcheva TM, Keller CW, Quast I, Leontyev D, Djoumerska-Alexieva IK, Kasermann F, Jakob SM, Peyta D, Branch D, Cummings J, Kaufmann T, Simon H, Von Gunten S 2017 Sci Rep View Researchers Basic research
Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa Donkor DA, Bhakta V, Eltringham-Smith LJ, Stafford AR, Weitz JI, Sheffield WP 2017 Sci Rep View Researchers Basic research
QSAR accelerated discovery of potent ice recrystallization inhibitors Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN 2016 Sci Rep View Researchers Basic research
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G 2022 Sci Rep View Researchers Clinical research
Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood Guo Q, Duffy SP, Matthews K, Islamzada E, Ma H 2017 Sci Rep View Researchers New or improved product or process
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN 2015 Sci Rep View Researchers New or improved product or process
Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing Briard JG, Poisson JS, Turner TR, Capicciotti CJ, Acker JP, Ben RN 2016 Sci Rep View Researchers New or improved product or process
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M 2016 Sci Rep View Researchers Basic research
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP 2021 Sci Rep View Researchers Basic research
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H 2021 Sci Rep View Researchers Clinical research
A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli Hun Yeon J, Chan KYT, Wong T-C, Chan K, Sutherland MR, Ismagilov RF, Pryzdial ELG, Kastrup CJ 2015 Sci Rep View Researchers Basic research
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E 2016 Sci Rep View Researchers Basic research
Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP 2019 Sci Rep View Researchers Basic research
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM 2015 Sci Rep View Researchers Basic research
A bioinformatics approach to identify natural autoantibodies from healthy blood donors' sera reactive with the HCV NS5A-derived peptide by immunoassay Vasiljevic N, Veljkovic N, Kosec T, Ma XZ, Glisic S, Prljic J, Vujicic AD, Markovic L, Branch DR 2011 Viral Immunol View Researchers Basic research
Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia Arnold DM, Nazi I, Toltl LJ, Ross C, Ivetic N, Smith JW, Liu Y, Kelton JG 2015 Eur J Haematol View Researchers Clinical research
A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia Mahabir VK, Ross C, Popovic S, Sur ML, Bourgeois J, Lim W, George JN, Wang G, Cook RJ, Toltl LJ, Nazi I, Kelton JG, Arnold DM 2013 Eur J Haematol View Health care providers Clinical research
Bacterial neuraminidase-mediated erythrocyte desialylation provokes cell surface aminophospholipid exposure Qadri SM, Donkor DA, Nazy I, Branch DR, Sheffield WP 2018 Eur J Haematol View Researchers Basic research
Impact of osteoblast maturation on their paracrine growth enhancing activity on cord blood progenitors Alsheikh M, Abu?Khader A, Michalicka M, Pasha R, Pineault N 2017 Eur J Haematol View Researchers Basic research
How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the Canadian PNH Network and review of the national registry Patriquin CJ, Kiss T, Caplan S, Chin-Yee I, Grewal K, Grossman J, Larratt L, Marceau D, Nevill T, Sutherland DR, Wells RA, Leber B 2019 Eur J Haematol View Researchers Clinical research