Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss | Sheffield WP, Eltringham-Smith LJ, Bhakta V | 2018 | BMC Biotechnol | View A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss | Researchers | Basic research |
Evaluating the Clinical Effect of Female Blood Donors of Child-Bearing Age on Maternal and Neonatal Outcomes: A Cohort Study | Chassé M, Tinmouth A, Goldman M, O'Brien SF, Hawken S, Murphy MSQ, Walker M, Sprague AE, Wilson K, van Walraven C, Fergusson DA | 2019 | Transfus Med Rev | View Evaluating the Clinical Effect of Female Blood Donors of Child-Bearing Age on Maternal and Neonatal Outcomes: A Cohort Study | Researchers | Clinical research |
Isoagglutinin-reduced immunoglobulin retains efficacy in mouse models of immune thrombocytopenia and rheumatoid arthritis and is less likely to cause intravenous immunoglobulin–associated hemolysis | Cen SY, Branch DR | 2020 | Transfusion | View Isoagglutinin-reduced immunoglobulin retains efficacy in mouse models of immune thrombocytopenia and rheumatoid arthritis and is less likely to cause intravenous immunoglobulin–associated hemolysis | Researchers | Basic research |
Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fc? receptor inhibition | Norris PAA, Kaur G, Khan R, Zhu G, Ni H, Lazarus AH | 2021 | Blood | View Anti-inflammatory activity of CD44 antibodies in murine immune thrombocytopenia is mediated by Fc? receptor inhibition | Researchers | Basic research |
Daudi cell stroma: An alternative to dithiothreitol to resolve daratumumab interference in pretransfusion testing | Tremblay T, Branch DR, Loubaki L | 2020 | Transfusion | View Daudi cell stroma: An alternative to dithiothreitol to resolve daratumumab interference in pretransfusion testing | Researchers | New or improved product or process |
High subzero cryofixation: A technique for observing ice within tissues | Lautner L, William N, Acker JP | 2020 | Cryobiology | View High subzero cryofixation: A technique for observing ice within tissues | Researchers | New or improved product or process |
The mega-importance of de novo lipogenesis in platelet production | Nazy I, Arnold DM, Steinberg GR | 2020 | Nat Metab | View The mega-importance of de novo lipogenesis in platelet production | Researchers | Basic research |
The impact of extended half-life factor concentrates on patient reported health outcome measures in persons with hemophilia A and hemophilia B | Sun HL, Yang M, Poon MC, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S | 2021 | Res Pract Thromb Haemost | View The impact of extended half-life factor concentrates on patient reported health outcome measures in persons with hemophilia A and hemophilia B | Researchers | Clinical research |
Assessment of bacterial growth in leukoreduced cold-stored whole blood supports overnight hold at room temperature prior to filtration: A pilot study | Ramirez-Arcos S, Kou Y, Kumaran D, Culibrk B, Stewart T, Schubert P, McTaggart K | 2022 | Vox Sang | View Assessment of bacterial growth in leukoreduced cold-stored whole blood supports overnight hold at room temperature prior to filtration: A pilot study | Researchers | New or improved product or process |
Heterogeneity of Vaccine-Induced Immune Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination and Safety of Second Vaccination with BNT162b2 | Lindhoff-Last E, Schoenborn L, Piorkowski M, Herold J, Greinacher A, Sheppard JA, Warkentin TE | 2022 | Thromb Haemost | View Heterogeneity of Vaccine-Induced Immune Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination and Safety of Second Vaccination with BNT162b2 | Researchers | Clinical research |
Blood unit segments accurately represent the biophysical properties of red blood cells in blood bags but not hemolysis | Islamzada E, Matthews K, Lamoureux E, Duffy SP, Scott MD, Ma H | 2022 | Transfusion | View Blood unit segments accurately represent the biophysical properties of red blood cells in blood bags but not hemolysis | Researchers | Basic research |
Combined preoperative plasma exchange and red blood cell exchange transfusion in a renal transplant patient with protein S deficiency and hemoglobin SC disease | Cook O, Cervi A, Laureano M, Gangji AS, Verhovsek M | 2021 | Transfus Apher Sci | View Combined preoperative plasma exchange and red blood cell exchange transfusion in a renal transplant patient with protein S deficiency and hemoglobin SC disease | Researchers | Clinical research |
Concentré de recherche: Suggestion concernant le mécanisme en jeu dans la thrombocytopénie thrombotique induite par le vaccin | Batarfi K | 2021 | Blood.ca website | View Concentré de recherche: Suggestion concernant le mécanisme en jeu dans la thrombocytopénie thrombotique induite par le vaccin | Researchers | Clinical research |
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients | Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP, on behalf of the MARS Consortium | 2022 | Blood Adv | View Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients | Researchers | Clinical research |
Lessons learned from the CONCOR-1 trial | Callum J, Bégin P, Jamula E, Liu Y, Kron AT, Auclair MC, Cushing M, Arnold DM | 2023 | Transfus Med | View Lessons learned from the CONCOR-1 trial | Researchers | Clinical research |
A Portrait of Cord Blood Units Distributed for Transplantation from Canadian Blood Services’ Cord Blood Bank: First Analysis | Parmar G, Green M, Mostert K, Lawless T, Dibdin N, Weiss J, Ganz K, Petraszko T, Seftel MD, Allan DS | 2022 | Curr Oncol | View A Portrait of Cord Blood Units Distributed for Transplantation from Canadian Blood Services’ Cord Blood Bank: First Analysis | Researchers | Benchmarking and standard setting |
Chemoenzymatic Synthesis of a Type 2 Blood Group A Tetrasaccharide and Development of High-throughput Assays Enables a Platform for Screening Blood Group Antigen-cleaving Enzymes | Kwan DH, Ernst S, Kotzler MP, Withers SG | 2015 | Glycobiology | View Chemoenzymatic Synthesis of a Type 2 Blood Group A Tetrasaccharide and Development of High-throughput Assays Enables a Platform for Screening Blood Group Antigen-cleaving Enzymes | Researchers | Basic research |
Concentré de recherche: Comment se comportent les bactéries lors de la fabrication des plaquettes? | Ramirez-Arcos S | 2017 | Blood.ca website | View Concentré de recherche: Comment se comportent les bactéries lors de la fabrication des plaquettes? | Researchers | Basic research |
Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol | Suen CM, Zhai A, Lalu MM, Welsh C, Levac BM, Fergusson D, McIntyre L, Stewart DJ | 2016 | Syst Rev | View Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol | Researchers | Basic research |
Fc-independent phagocytosis: Implications for IVIG and other therapies in immune-mediated thrombocytopenia | Li J, van der Wal DE, Zhu L, Vadasz B, Simpson EK, Li C, Webster ML, Zhu G, Lang S, Chen P, Zeng Q, Ni H | 2013 | Cardiovasc Hematol Disord Drug Targets | View Fc-independent phagocytosis: Implications for IVIG and other therapies in immune-mediated thrombocytopenia | Researchers | Other |
Introduction to the special issue: Teaching healthcare operations research, part 2 | Blake J | 2017 | INFORMS Transactions on Education | View Introduction to the special issue: Teaching healthcare operations research, part 2 | Researchers | New or improved product or process |
Low-dose decitabine promotes megakaryocyte maturation and platelet production in healthy controls and immune thrombocytopenia | Zhou H, Hou Y, Liu X, Qiu J, Feng Q, Wang Y, Zhang X, Min Y, Shao L, Liu X, Li G, Li L, Yang L, Xu S, Ni H, Peng J, Hou M | 2015 | Thromb Haemost | View Low-dose decitabine promotes megakaryocyte maturation and platelet production in healthy controls and immune thrombocytopenia | Researchers | Basic research |
Microparticles as biomarkers of lung disease - enumeration in biological fluids using lipid bilayer microspheres | McVey MJ, Spring C, Semple JW, Maishan M, Kuebler WM | 2016 | Am J Physiol Lung Cell Mol Physiol | View Microparticles as biomarkers of lung disease - enumeration in biological fluids using lipid bilayer microspheres | Researchers | Basic research |
p38MAPK is involved in apoptosis development in apheresis platelet concentrates after riboflavin and ultraviolet light treatment | Chen Z, Schubert P, Culibrk B, Devine DV | 2014 | Transfusion | View p38MAPK is involved in apoptosis development in apheresis platelet concentrates after riboflavin and ultraviolet light treatment | Researchers | Basic research |
QSAR accelerated discovery of potent ice recrystallization inhibitors | Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN | 2016 | Sci Rep | View QSAR accelerated discovery of potent ice recrystallization inhibitors | Researchers | Basic research |
Reduction of thrombus size in murine models of thrombosis following administration of recombinant alpha1-proteinase inhibitor mutant proteins | Sheffield WP, Eltringham-Smith LJ, Bhakta V, Gataiance S | 2012 | Thromb Haemost | View Reduction of thrombus size in murine models of thrombosis following administration of recombinant alpha1-proteinase inhibitor mutant proteins | Researchers | Basic research |
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment | Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV | 2013 | Transfusion | View Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment | Researchers | Basic research |
SHP-1 protein tyrosine phosphatase associates with the adaptor protein CrkL | Evren S, Ma XZ, Sakac D, Branch DR | 2012 | Exp Hematol | View SHP-1 protein tyrosine phosphatase associates with the adaptor protein CrkL | Researchers | Basic research |
Sustained expression of coagulation Factor IX by modified cord blood-derived mesenchymal stromal cells | Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G | 2014 | J Gene Med | View Sustained expression of coagulation Factor IX by modified cord blood-derived mesenchymal stromal cells | Researchers | Basic research |
The procoagulant envelope virus surface: contribution to enhanced infection | Pryzdial EL, Sutherland MR, Ruf W | 2014 | Thromb Res | View The procoagulant envelope virus surface: contribution to enhanced infection | Researchers | Basic research |
Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model | Tiller H, Killie MK, Chen P, Eksteen M, Husebekk A, Skogen B, Kjeldsen-Kragh J, Ni H | 2012 | Transfusion | View Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model | Researchers | Basic research |
Unexpected suppression of anti-Fya and prevention of hemolytic disease of the fetus and newborn after administration of Rh immune globulin | Branch DR, Scofield TL, Moulds JJ, Swanson JL | 2011 | Transfusion | View Unexpected suppression of anti-Fya and prevention of hemolytic disease of the fetus and newborn after administration of Rh immune globulin | Researchers | Basic research |
Changes in minimum hemoglobin and interdonation interval: impact on donor hemoglobin and donation frequency | Goldman M, Yi Q-L, Steed T, O'Brien SF | 2019 | Transfusion | View Changes in minimum hemoglobin and interdonation interval: impact on donor hemoglobin and donation frequency | Researchers | New or improved product or process |
The potential role of a turbidimetric heart-type fatty acid-binding protein assay to aid in the interpretation of persistently elevated, non-changing, cardiac troponin I concentrations | Kavsak PA, Ainsworth C, Arnold DM, Scott T, Clark L, Ivica J, Mackett K, Whitlock R, Worster A | 2018 | Clin Biochem | View The potential role of a turbidimetric heart-type fatty acid-binding protein assay to aid in the interpretation of persistently elevated, non-changing, cardiac troponin I concentrations | Researchers | Basic research |
Synthesis of Highly Biocompatible and Temperature-Responsive Physical Gels for Cryopreservation and 3D Cell Culture | Nagao M, Sengupta J, Diaz-Dussan D, Adam M, Wu M, Acker J, Ben R, Ishihara K, Zeng H, Miura Y, Narain R | 2018 | ACS Appl Bio Mater | View Synthesis of Highly Biocompatible and Temperature-Responsive Physical Gels for Cryopreservation and 3D Cell Culture | Researchers | Basic research |
Transfusion-related acute lung injury (TRALI) | Petraszko T | 2019 | Blood.ca website | View Transfusion-related acute lung injury (TRALI) | Researchers | Clinical research |
Virus envelope tissue factor promotes infection in mice | Sutherland MR, Simon AY, Shanina I, Horwitz MS, Ruf W, Pryzdial ELG | 2019 | J Thromb Haemost | View Virus envelope tissue factor promotes infection in mice | Researchers | Basic research |
Model Human ? Thalassemic Erythrocytes: Effect of Unpaired Purified ?-Hemoglobin Chains on Normal Erythrocytes | Scott M | 2019 | Beta Thalassemia | View Model Human ? Thalassemic Erythrocytes: Effect of Unpaired Purified ?-Hemoglobin Chains on Normal Erythrocytes | Researchers | Basic research |
ResearchUnit: Improving quality testing of stem cells for patients | Pineault N | 2020 | Blood.ca website | View ResearchUnit: Improving quality testing of stem cells for patients | Researchers | New or improved product or process |
Trehalose-Based Polyethers for Cryopreservation and Three-Dimensional Cell Scaffolds | Diaz-Dussan D, Peng YY, Sengupta J, Zabludowski R, Adam MK, Acker JP, Ben RN, Kumar P, Narain R | 2020 | Biomacromolecules | View Trehalose-Based Polyethers for Cryopreservation and Three-Dimensional Cell Scaffolds | Researchers | Basic research |
A comparison of methods for prediction of pharmacokinetics when switching to extended half-life products in hemophilia A patients | Yu JK, Iorio A, Edginton AN | 2020 | Thromb Res | View A comparison of methods for prediction of pharmacokinetics when switching to extended half-life products in hemophilia A patients | Researchers | Clinical research |
Donor-dependent aging of young and old red blood cell subpopulations: Metabolic and functional heterogeneity | Mykhailova O, Olafson C, Turner TR, D?Alessandro A, Acker JP | 2020 | Transfusion | View Donor-dependent aging of young and old red blood cell subpopulations: Metabolic and functional heterogeneity | Researchers | Basic research |
Industry, experts and the role of the ‘invisible college’ in the dissemination of non-invasive prenatal testing in the US | Holloway K, Miller FA, Simms N | 2021 | Soc Sci Med | View Industry, experts and the role of the ‘invisible college’ in the dissemination of non-invasive prenatal testing in the US | Researchers | Ethical, legal and social implications research |
Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion | Heddle NM, Cardoso M, van der Meer PF | 2020 | Transfusion | View Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion | Researchers | Clinical research |
Transient warming affects potency of cryopreserved cord blood units | Pasha R, Howell A, Turner TR, Halpenny M, Elmoazzen H, Acker JP, Pineault N | 2020 | Cytotherapy | View Transient warming affects potency of cryopreserved cord blood units | Researchers | New or improved product or process |
Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs | Wang A, Ribeiro RVP, Ali A, Brambate E, Abdelnour-Berchtold E, Michaelsen V, Zhang Y, Rahfeld P, Moon H, Gokhale H, Gazzalle A, Pal P, Liu M, Waddell TK, Cserti-Gazdewich C, Tinckam K, Kizhakkedathu JN, West L, Keshavjee S, Withers SG, Cypel M | 2022 | Sci Transl Med | View Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs | Researchers | Clinical research |
Meta-Analysis of Risk of Vaccine-Induced Immune Thrombotic Thrombocytopenia Following ChAdOx1-S Recombinant Vaccine | Chan BT, Bobos P, Odutayo A, Pai M | 2021 | medRxiv | View Meta-Analysis of Risk of Vaccine-Induced Immune Thrombotic Thrombocytopenia Following ChAdOx1-S Recombinant Vaccine | Researchers | Clinical research |
The Effect of Sex-Mismatched Red Blood Cell Transfusion on Endothelial Cell Activation in Critically Ill Patients | Alshalani A, van Manen L, Boshuizen M, van Bruggen R, Acker JP, Juffermans NP | 2021 | Transfus Med Hemotherapy | View The Effect of Sex-Mismatched Red Blood Cell Transfusion on Endothelial Cell Activation in Critically Ill Patients | Researchers | Clinical research |
Mixing study to diagnose heparin-resistance caused by functional antithrombin deficiency | Bahabri A, Moffat KA, Carlino SA, Chan AKC, Bhatt MD | 2022 | Int J Lab Hematol | View Mixing study to diagnose heparin-resistance caused by functional antithrombin deficiency | Researchers | Basic research |
Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner | De Silva E, Devine DV, Jan E, Roskelley CD, Kim H | 2022 | Biochem J | View Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner | Researchers | Basic research |