Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Preparation of blood products for transfusion: is there a best method? Devine DV, Serrano K 2012 Biologicals View Blood operators Other
Mesenchymal stromal cells derived from umbilical cord blood migrate in response to complement C1q Qiu Y, Marquez-Curtis LA, Janowska-Wieczorek A 2012 Cytotherapy View Researchers Basic research
Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury Cho N, Nguyen DH, Satkunendrarajah K, Branch DR, Fehlings MG 2012 J Neuroinflammation View Researchers Basic research
Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease-activated receptor 2 cofactors that enhance infection Sutherland MR, Ruf W, Pryzdial EL 2012 Blood View Researchers Basic research
Acquired hemophilia A Webert KE 2012 Semin Thromb Hemost View Health care providers Other
Influence of architecture of high molecular weight linear and branched polyglycerols on their biocompatibility and biodistribution Imran ul-haq M, Lai BF, Chapanian R, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
Preserving and using germplasm and dissociated embryonic cells for conserving Caribbean and Pacific coral Hagedorn M, Carter V, Martorana K, Paresa MK, Acker J, Baums IB, Borneman E, Brittsan M, Byers M, Henley M, Laterveer M, Leong JA, McCarthy M, Meyers S, Nelson BD, Petersen D, Tiersch T, Uribe RC, Woods E, Wildt D 2012 PLoS One View Researchers Basic research
Transfusion reactions: a comparative observational study of blood components produced before and after implementation of semiautomated production from whole blood Semple E, Bowes-Schmidt A, Yi QL, Shimla S, Devine DV 2012 Transfusion View Blood operators New or improved product or process
Decreased indoleamine 2,3-dioxygenase expression in dendritic cells and role of indoleamine 2,3-dioxygenase-expressing dendritic cells in immune thrombocytopenia Xu SQ, Wang CY, Zhu XJ, Dong XY, Shi Y, Peng J, Qin P, Sun JZ, Guo C, Ni H, Hou M 2012 Ann Hematol View Researchers Basic research
Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway Krisinger MJ, Goebeler V, Lu Z, Meixner SC, Myles T, Pryzdial EL, Conway EM 2012 Blood View Researchers Basic research
Alloimmunization of patients by blood units harboring distinct DEL variants St-Louis M, Lebrun A, Goldman M, Lavoie M 2013 Immunohematology View Health care providers Clinical research
Fc-independent phagocytosis: Implications for IVIG and other therapies in immune-mediated thrombocytopenia Li J, van der Wal DE, Zhu L, Vadasz B, Simpson EK, Li C, Webster ML, Zhu G, Lang S, Chen P, Zeng Q, Ni H 2013 Cardiovasc Hematol Disord Drug Targets View Researchers Other
Identifying D-positive donors using a second automated testing platform Goldman M, Resz I, Cote J, Ochoa G, Angus N 2013 Immunohematology View Blood operators New or improved product or process
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV 2013 Transfusion View Researchers Basic research
CD4+ T-cells are unable to express the HIV natural resistance factor globotriosylceramide Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR 2013 AIDS View Researchers Basic research
Developing highly active small molecule ice recrystallization inhibitors based upon C-linked antifreeze glycoprotein analogues Trant JF, Briggs RA, Capicciotti C, Ben RN 2013 RSC Adv View Researchers Basic research
ResearchUnit: Should patients receive HLA-selected platelets? Shehata N 2013 Blood.ca website View Other Other
Utilization of frozen plasma in Ontario: a province wide audit reveals a high rate of inappropriate transfusions Tinmouth A, Thompson T, Arnold DM, Callum JL, Gagliardi K, Lauzon D, Owens W, Pinkerton P 2013 Transfusion View Health care providers Benchmarking and standard setting
Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain Kurbegovic A, Trudel M 2013 Hum Mol Genet View Researchers Basic research
ResearchUnit: Doubling the 30-minute rule without compromising Red Blood Cells quality and safety. Ramirez-Arcos S 2013 Blood.ca website View Other Other
Thrombocytopenia in the critically ill Shehata N, Fontes ML 2013 Can J Anaesth View Researchers Other
Allowing blood donation from men who had sex with men more than 5 years ago: a model to evaluate the impact on transfusion safety in Canada Germain M, Robillard P, Delage G, Goldman M 2013 Vox Sang View Blood operators New or improved product or process
Design of long circulating nontoxic dendritic polymers for the removal of iron in vivo Imran ul-haq M, Hamilton JL, Lai BF, Shenoi RA, Horte S, Constantinescu I, Leitch HA, Kizhakkedathu JN 2013 ACS Nano View Researchers Basic research
Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review Pavenski K, Rebulla P, Duquesnoy R, Saw CL, Slichter SJ, Tanael S, Shehata N, International Collaboration for Guideline Development Implementation and Evaluation for Transfusion Therapies (ICTMG) Collaborators 2013 Transfusion View Researchers Clinical research
N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes Shmukler BE, Hsu A, Alves J, Trudel M, Rust MB, Hubner CA, Rivera A, Alper SL 2013 Blood Cells Mol Dis View Researchers Basic research
Posttransplant monitoring of de novo human leukocyte antigen donor-specific antibodies in kidney transplantation Wiebe C, Nickerson P 2013 Curr Opin Organ Transplant View Health care providers Clinical research
Sustained remissions of immune thrombocytopenia associated with the use of thrombopoietin receptor agonists Ghadaki B, Nazi I, Kelton JG, Arnold DM 2013 Transfusion View Health care providers Clinical research
Unraveling the IVIG mystique Branch DR 2013 Transfusion View Researchers Other
What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers Lane S, Arnold E, Webert KE, Chan A, Walker I, Heddle NM 2013 Haemophilia View Health care providers Other
An enclosed in-gel PCR amplification cassette with multi-target, multi-sample detection for platform molecular diagnostics Manage DP, Lauzon J, Atrazev A, Chavali R, Samuel RA, Chan B, Morrissey YC, Gordy W, Edwards AL, Larison K, Yanow SK, Acker JP, Zahariadis G, Pilarski LM 2013 Lab Chip View Health care providers New or improved product or process
CD44 antibodies and immune thrombocytopenia in the amelioration of murine inflammatory arthritis Mott PJ, Lazarus AH 2013 PLoS One View Researchers Basic research
Advancing risk assessment for emerging infectious diseases for blood and blood products: proceedings of a public workshop Gallagher LM, Ganz PR, Yang H, Kessler DA, O'Brien SF, Custer BS, Busch MP, Dodd RY, Stramer SL, Walderhaug MO, Forshee RA, Williams AE, Epstein JS, Anderson SA 2013 Transfusion View Blood operators Other
Blood component transfusion in critically ill patients McIntyre L, Tinmouth AT, Fergusson DA 2013 Curr Opin Crit Care View Health care providers Clinical research
E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1alpha/CXCR4 Sun J, Li Y, Graziani GM, Filion L, Allan DS 2013 PLoS One View Researchers Basic research
Antigens protected functional red blood cells by the membrane grafting of compact hyperbranched polyglycerols Chapanian R, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu J 2013 J Vis Exp View Researchers Basic research
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N 2013 Nat Med View Researchers Basic research
Febrile and allergic transfusion reactions Fung MK, Heddle NM 2013 Practical Transfusion Medicine, 4th edition View Health care providers Clinical research
The rationale for platelet transfusion during cardiopulmonary bypass: an observational study Zaffar N, Joseph A, Mazer CD, Nisenbaum R, Karkouti K, Tinmouth A, Peterson MD, Pavenski K, Callum J, Cserti-Gazdewich C, Shehata N 2013 Can J Anaesth View Health care providers Clinical research
What to do with the queue? Reducing wait times for cancer care Blake JT, Bolland D, Dawe I 2013 Case Studies in Health Policy and Management, 2nd Edition View Other Other
Activated platelets can deliver mRNA regulatory Ago2-microRNA complexes to endothelial cells via microparticles Laffont B, Corduan A, Plé H, Duchez AC, Cloutier N, Boilard E, Provost P 2013 Blood View Researchers Basic research
Donor selection for recipient safety Goldman M 2013 ISBT Sci Ser View Health care providers Clinical research
ResearchUnit: Supporting evidence to change regulations regarding the storage of cryosupernatant plasma. Sheffield W 2013 Blood.ca website View Other Other
The impact of prolonged storage of red blood cells on cancer survival Kekre N, Mallick R, Allan D, Tinmouth A, Tay J 2013 PLoS One View Health care providers Clinical research
Microfluidic analysis of cellular deformability of normal and oxidatively-damaged red blood cells Kwan JM, Quan Guo Q, Kyluik-Price DL, Ma H, Scott MD 2013 Am J Hematol View Researchers Basic research
The epidemiology of human T-cell lymphotropic virus types I and II in Canadian blood donors O'Brien SF, Goldman M, Scalia V, Yi QL, Fan W, Xi G, Dines IR, Fearon MA 2013 Transfus Med View Blood operators Clinical research
Exploring resource allocation and alternate clinic accessibility landscapes for improved blood donor turnout Paez A, Esita J, Newbold KB, Heddle NM, Blake JT 2013 Appl Geogr View Blood operators New or improved product or process
Rapid removal of glycerol from frozen-thawed red blood cells Lusianti RE, Benson JD, Acker JP, Higgins AZ 2013 Biotechnol Prog View Researchers New or improved product or process
Rejuvenation of ATP during storage does not reverse effects of the hypothermic storage lesion Tchir JD, Acker JP, Holovati JL 2013 Transfusion View Researchers Basic research
Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis Lauzier F, Arnold DM, Rabbat C, Heels-Ansdell D, Zarychanski R, Dodek P, Ashley BJ, Albert M, Khwaja K, Ostermann M, Skrobik Y, Fowler R, McIntyre L, Nates JL, Karachi T, Lopes RD, Zytaruk N, Finfer S, Crowther M, Cook D 2013 Intensive Care Med View Health care providers Clinical research
Drugs in ITP: Mechanisms of Action Crow AR, Lazarus AH 2013 Immune Thrombocytopenia (ITP) View Researchers Other