Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Red cell supernatant effects on endothelial cell function and innate immune activation is influenced by donor age and sex Kipkeu BJ, Almizraq R, Branch DR, Acker JP, Holovati JL 2018 ISBT Sci Ser View Researchers Basic research
Window to the Unknown: Using Storytelling to Identify Learning Needs for the Intrinsic Competencies Within an Online Needs Assessment Tseng EK, Jo D, Shih AW, De Wit K, Chan TM 2018 AEM Educ Train View Researchers Education research
Cryoprotection of platelets by grafted polymers Scott M, Nakane N, Maurer-Spurej E 2019 Cryopreservation - Current Advances and Evaluations View Researchers Basic research
Monitoring of prenatal patients using a combined antibody titre for Rh and non-Rh antibodies Farrell M, Clarke G, Barr G, Hannon J 2020 Transfus Med View Researchers Clinical research
Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc-?TP-L309C, a recombinant IgG1 Fc hexamer Lewis BJB, Ville J, Blacquiere M, Cen S, Spirig R, Zuercher AW, Käsermann F, Branch DR 2019 BMC Immunol View Researchers Basic research
Evaluation of the effect of T regulatory cell depletion and donor BCG vaccination on Mycobacterium tuberculosis H37Ra infection using an in vitro model of human PBMC infection Bhavanam S, Rayat GR, Keelan M, Kunimoto D, Drews SJ 2020 Pathog Dis View Researchers Basic research
Insights Into the Hematopoietic Regulatory Activities of Osteoblast by Secretomics Hovey O, Pasha R, Lehmann Z, Pineault N 2020 Proteomics View Researchers Basic research
The role of fluid-phase immune complexes in the pathogenesis of heparin-induced thrombocytopenia Huynh A, Arnold DM, Smith JW, Elliott TD, Ivetic N, Kelton JG, Nazy I 2020 Thromb Res View Researchers Basic research
Digital Microfluidic Hemagglutination Assays for Blood Typing, Donor Compatibility Testing, and Hematocrit Analysis Sklavounos AA, Lamanna J, Modi D, Gupta S, Mariakakis A, Callum J, Wheeler AR 2021 Clin Chem View Researchers New or improved product or process
Vaccine-induced immune thrombotic thrombocytopenia Klok FA, Pai M, Huisman MV, Makris M 2022 Lancet Haematol View Researchers Clinical research
International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses Al-Riyami AZ, Burnouf T, Yazer M, Triulzi D, Kuma? LT, Sa?dur L, Pelit NB, Bazin R, Hindawi SI, Badawi MA, Patidar GK, Pandey HC, Chaurasia R, Fachini RM, Scuracchio P, Wendel S, Ang AL, Ong KH, Young P, Ihalainen J, Vierikko A, Qiu Y, Yang R, Xu H, Rahimi-Levene N, Shinar E, Izak M, Gonzalez CA, Ferrari DM, Cini PV, Aditya RN, Sharma RR, Sachdev S, Hans R, Lamba DS, Nissen-Meyer LSH, Devine DV, Lee CK, Leung JN-S, Hung IFN, Tiberghien P, Gallian P, Morel P, Al Maamari K, Al-Hinai Z, Vrielink H, So-Osman C, De Angelis V, Berti P, Ostuni A, Marano G, Nevessignsky MT, El Ekiaby M, Daly J, Hoad V, Kim S, van den Berg K, Vermeulen M, Glatt TN, Schäfer R, Reik R, Gammon R, Lopez M, Estcourt L, MacLennan S, Roberts D, Louw V, Dunbar N 2021 Vox Sang View Researchers Clinical research
Structurally Modified Bioactive Peptide Inhibits SARS-CoV-2 Lentiviral Particles Expression Bhullar KS, Nael MA, Elokely KM, Drews SJ, Wu J 2022 Pharmaceutics View Researchers Basic research
Venous thromboembolism in pediatric inflammatory bowel disease: an 11-year population-based nested case-control study in Canada Ding Z, Sherlock M, Chan AKC, Zachos M 2022 Blood Coagul Fibrinolysis View Researchers Clinical research
Assessing unintentional creation of bias against men who have sex with men as a function of exposure to blood donor screening questionnaire: A national randomized controlled trial Hofkirchner A, Kohut T, O'Brien SF, Fisher WA 2022 Transfusion View Researchers MSM research
A novel compensating mechanism for homozygous coagulation factor V deficiency suggested by enhanced activated partial thromboplastin time after reconstitution with normal factor V Talbot K, Song J, Hewitt J, Serrano K, Ho M, Carter CJ, MacGillivray RTA, Pryzdial ELG 2010 Br J Haematol View Researchers Basic research
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M 2016 Sci Rep View Researchers Basic research
Coagulation factor X Arg386 specifically affects activation by the intrinsic pathway: a novel patient mutation Vanden Hoek AL, Talbot K, Carter IS, Vickars L, Carter CJ, Jackson SC, Macgillivray RT, Pryzdial EL 2012 J Thromb Haemost View Researchers Basic research
c-Src and Pyk2 protein tyrosine kinases play protective roles in early HIV-1 infection of CD4+ T cell lines McCarthy SDS, Jung D, Sakac D, Branch DR 2014 J Acquir Immune Defic Syndr View Researchers Basic research
Drugs in ITP: Mechanisms of Action Crow AR, Lazarus AH 2013 Immune Thrombocytopenia (ITP) View Researchers Other
Enhancing blood donor skin disinfection using natural oils Alabdullatif M, Boujezza I, Mekni M, Taha M, Kumaran D, Yi QL, Landoulsi A, Ramirez-Arcos S 2017 Transfusion View Researchers New or improved product or process
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment Iorio A, Edginton AN 2017 Haemophilia View Researchers Clinical research
High-quality randomized controlled trials in pediatric critical care: a survey of barriers and facilitators Duffett M, Choong K, Foster J, Meade M, Menon K, Parker M, Cook DJ 2017 Pediatr Crit Care Med View Researchers Clinical research
Inhibition of phagocytic recognition of anti-D opsonized Rh D+ RBC by polymer-mediated immunocamouflage Li L, Noumsi GT, Kwok YYE, Moulds JM, Scott MD 2015 Am J Hematol View Researchers Basic research
Label-free assessment of red blood cell storage lesions by deep learning Doan M, Sebastian JA, Pinto PN, McQuin C, Goodman A, Wolkenhauer O, Parsons MJ, Acker JP, Rees P, Hennig H, Kolios MC, Carpenter AE 2018 bioRxiv View Researchers New or improved product or process
Mechanisms of platelet recovery in ITP associated with therapy Pang SJY, Lazarus AH 2010 Ann Hematol View Researchers Basic research
Nucleic acid extraction from buccal tissue for prediction of red blood cell phenotype Berardi P, Cote J, Clarke G, Scalia V, Liwski R, Goldman M 2017 Transfusion View Researchers New or improved product or process
Role of G protein-coupled vasoactive intestinal peptide receptors in HIV integration Branch DR 2011 Future Virol View Researchers Basic research
Testosterone-dependent sex differences in red blood cell hemolysis in storage, stress, and disease Kanias T, Sinchar D, Osei-Hwedieh D, Baust JJ, Jordan A, Zimring JC, Waterman HR, de Wolski KS, Acker JP, Gladwin MT 2016 Transfusion View Researchers Basic research
Transfusion-associated circulatory overload prevention: a retrospective observational study of diuretic use Lin Y, Cohen R, Armali C, Callum J, Cserti-Gazdewich C, Lieberman L, Pendergrast J 2018 Vox Sang View Researchers Clinical research
Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity of red blood cell products and charactersitics of extracellular vesicles. Almizraq RJ, Norris PJ, Inglis H, Menocha S, Wirtz MR, Juffermans N, Pandey S, Spinella PC, Acker JP, Muszynski JA 2018 Blood Adv View Researchers Basic research
Microvascular Thrombosis and Ischaemic Limb Losses in Critically Ill Patients Warkentin TE 2019 Hämostaseologie View Researchers Clinical research
Inhibition of ice recrystallization during cryopreservation of cord blood grafts improves platelet engraftment Jahan S, Adam MK, Manesia JK, Doxtator E, Ben RN, Pineault N 2020 Transfusion View Researchers Basic research
Platelet factor 4 inhibits ADAMTS13 activity and regulates the multimeric distribution of von Willebrand factor Nazy I, Elliott TD, Arnold DM 2020 Br J Haematol View Researchers Basic research
A suspected septic transfusion reaction associated with posttransfusion contamination of a platelet pool by vancomycin-resistant Enterococcus faecium Drews SJ, Lesley P, Detsky ME, Distefano L, Ilagan C, Mehta S, McGeer A, Shehata N, Skeate R, Ramirez-Arcos S 2020 Transfusion View Researchers Basic research
Clinically approved IVIg delivered to the hippocampus with focused ultrasound promotes neurogenesis in a model of Alzheimer’s disease Dubey S, Heinen S, Krantic S, McLaurin J, Branch DR, Hynynen K, Aubert I 2020 PLoS Pathog View Researchers Basic research
Proliferative and Regenerative Effect of Acetonic Extract of Feijoa sellowiana on Stem Cells Rasekh H, Hoseini Farahi M, Mehrabani D, Massoumi SJ, Ramzi M, Acker JP 2020 World J Plast Surg View Researchers Basic research
Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant Hamada M, Bhakta V, Andres SN, Sheffield WP 2021 Front Cardiovasc Med View Researchers Basic research
Estimating SARS-CoV-2 Seroprevalence in Canadian Blood Donors, April 2020 to March 2021: Improving Accuracy with Multiple Assays Tuite AR, Fisman D, Abe KT, Rathod B, Pasculescu A, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Drews SJ, Pride DT 2022 Microbiol Spectr View Researchers Basic research
Current challenges of severe acute respiratory syndrome coronavirus 2 seroprevalence studies among blood donors: A scoping review Saeed S, Uzicanin S, Lewin A, Lieshout-Krikke R, Faddy H, Erikstrup C, Osiowy C, Seed CR, Steele WR, Davison K, Custer B, O'Brien SF, Assessment SR, Policy Sub-group of the Transfusion Transmitted Infectious Diseases Working Party of the International Society of Blood Transfusion 2022 Vox Sang View Researchers Basic research
Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells Karakas D, Li J, Ni H 2021 Blood View Researchers Basic research
Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein Greinacher A, Selleng K, Mayerle J, Palankar R, Wesche J, Reiche S, Aebischer A, Warkentin TE, Muenchhoff M, Hellmuth JC, Keppler OT, Duerschmied D, Lother A, Rieg S, Gawaz MP, Mueller KAL, Scheer CS, Napp M, Hahnenkamp K, Lucchese G, Vogelgesang A, Flöel A, Lovreglio P, Stufano A, Marschalek R, Thiele T 2021 Blood View Researchers Clinical research
Risk factors for neonatal thrombosis: A retrospective study conducted in a single Canadian intensive care unit Bhatia K, Solanki S, Paes B, Chan AKC, Bhatt MD 2022 Pediatr Blood Cancer View Researchers Clinical research
Mitapivat versus Placebo for Pyruvate Kinase Deficiency Al-Samkari H, Galactéros F, Glenthøj A, Rothman JA, Andres O, Grace RF, Morado-Arias M, Layton DM, Onodera K, Verhovsek M, Barcellini W, Chonat S, Judge MP, Zagadailov E, Xu R, Hawkins P, Beynon V, Gheuens S, van Beers EJ 2022 N Engl J Med View Researchers Clinical research
Chemokines IP-10/CXCL10 and IL-8/CXCL8 are potential novel biomarkers of warm autoimmune hemolytic anemia Branch DR, Leger RM, Sakac d, Yi Q, Duong T, Yeung RSM, Binnington B, Bloch EM 2022 Blood Adv View Researchers Basic research
Adjudicating the Diagnosis of Immune Thrombocytopenia in a Clinical Research Study Gabe C, Mahamad S, John M, Duncan J, Kelton J, Arnold D 2023 TH Open View Researchers Clinical research
Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance O’Brien SF, Reedman CN, Osiowy C, Bolotin S, Yi Q-L, Lourenço L, Lewin A, Binka M, Caffrey N, Drews SJ 2023 Viruses View Researchers Clinical research
Rapid potency assessment of autologous peripheral blood stem cells by intracellular flow cytometry: the PBSC-IL-3-pSTAT5 assay Simard C, Fournier D, Pineault N, Trépanier P 2022 Cytotherapy View Researchers New or improved product or process
A role for red cell clearance in antibody-mediated inhibition of erythrocyte alloimmunization? Marjoram D, Cruz-Leal Y, Bernardo L, Lazarus AH 2017 ISBT Sci Ser View Researchers Basic research
Anti-A and anti-B: what are they and where do they come from? Branch DR 2015 Transfusion View Researchers Other
Bacteria can proliferate in thawed cryoprecipitate stored at room temperature for longer than 4 h Ramirez-Arcos S, Jenkins C, Sheffield W 2017 Vox Sang View Researchers Basic research