Our Research Publications
Updated November 2023
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Title | Authors | Year Sort ascending | Journal | Link to Article | Intended Audience | Purpose |
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Loss of repeat convalescent plasma donors due to waning anti-SARS-CoV-2 plaque reduction neutralization test titers (April-December 2020) | Drews S, Devine D, McManus J, Mendoza E, Manguiat K, Girardin R, Dupuis A, McDonough K, Lin J, Evans D, Pambrun C, Drebot M, Wood H | 2022 | Transfus Med Rev | View Loss of repeat convalescent plasma donors due to waning anti-SARS-CoV-2 plaque reduction neutralization test titers (April-December 2020) | Blood operators | New or improved product or process |
Plaquettes extraites de la couche leucoplaquettaire à teneur réduite en agents pathogènes | Blais-Normandin I, Tordon B, Anani W | 2022 | Blood.ca website | View Plaquettes extraites de la couche leucoplaquettaire à teneur réduite en agents pathogènes | Health care providers | Benchmarking and standard setting |
Methods to Evaluate the Potential Clinical Significance of Antibodies to Red Blood Cells | Boligan KF, Sandhu G, Branch DR | 2022 | Curr Protoc | View Methods to Evaluate the Potential Clinical Significance of Antibodies to Red Blood Cells | Researchers | Benchmarking and standard setting |
Management of immune‐mediated thrombocytopenia | Gabe C, Arnold D, Smith J, T W | 2022 | Rossi's Principles of Transfusion Medicine | View Management of immune‐mediated thrombocytopenia | Health care providers | Benchmarking and standard setting |
Why We Swab: A library of stories in stem cell donation | Jagelaviciute G, Kum E, Li EW, Rosenfeld A, Williams K, Kandel R, DeGurse N, Park B, Okonofua S, Sano L, Gerofsky M, Sharp A, Hatkar R, Thyagu S, Fingrut WB | 2022 | Transfusion | View Why We Swab: A library of stories in stem cell donation | Health care providers | Ethical, legal & social implications research |
Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 Viruses | Lin Y-CJ, Evans DH, Robbins NF, Orjuela G, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Yi Q-L, O’Brien SF, Drews SJ | 2022 | Microbiol Spectr | View Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 Viruses | Health care providers | Benchmarking and standard setting |
Les fournisseurs de sang canadiens : un rôle croissant dans la surveillance de la santé publique? | O’Brien SF, Drews SJ, Lewin A, Osiowy C, Drebot MA, Renaud C | 2022 | Relevé des maladies transmissibles au Canada | View Les fournisseurs de sang canadiens : un rôle croissant dans la surveillance de la santé publique? | Health care providers | New or improved product or process |
A mixed methods investigation of the relationship between blood donor policy, interest in donation, and willingness to donate among gay, bisexual, and other men who have sex with men in Ontario, Canada | Armstrong JP, Brennan DJ, Collict D, Kesler M, Bekele T, Souleymanov R, Grace D, Lachowsky NJ, Hart TA, Adam BD | 2022 | BMC Public Health | View A mixed methods investigation of the relationship between blood donor policy, interest in donation, and willingness to donate among gay, bisexual, and other men who have sex with men in Ontario, Canada | Researchers | MSM research |
Staff perspectives on barriers and enablers to implementing alternative source plasma eligibility criteria for gay, bisexual, and other men who have sex with men | Castillo G, Vesnaver E, Gibson E, Butler-Foster T, Goldman M, Hill NE, Rosser A, Lapierre D, Rubini KA, MacDonagh R, Miguel G, Palumbo A, MacPherson P, Randall T, Osbourne-Sorrell W, O'Brien SF, Bridel W, Otis J, Greaves M, Al-Bakri TB, Reid M, Labrecque M, Germain M, Orvis S, Clapperton AT, Devine D, Presseau J | 2022 | Transfusion | View Staff perspectives on barriers and enablers to implementing alternative source plasma eligibility criteria for gay, bisexual, and other men who have sex with men | Blood operators | MSM research |
A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic | Grunau B, O’Brien SF, Kirkham TL, Helmer J, Demers PA, Asamoah-Boaheng M, Drews SJ, Karim ME, Srigley JA, Sediqi S, O’Neill D, Drennan IR, Goldfarb DM | 2022 | Ann Emerg Med | View A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic | Researchers | Clinical research |
Déclaration du CCN concernant le génotypage du RHD chez les patientes enceintes | Pavenski K, Khandelwal A, Clarke G, Lane D | 2022 | National Advisory Committee on Blood and Blood Products | View Déclaration du CCN concernant le génotypage du RHD chez les patientes enceintes | Health care providers | Benchmarking and standard setting |
Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study | Alabdullatif M, Osman IE, Alrasheed M, Ramirez-Arcos S, Alyousef M, Althawadi S, Alhumiadan H | 2021 | Transfusion | View Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study | Researchers | New or improved product or process |
A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors | Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M | 2021 | Transfusion | View A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors | Researchers | Basic research |
Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference | Spinella PC, El Kassar N, Cap AP, Kindzelski AL, Almond CS, Barkun A, Gernsheimer TB, Goldstein JN, Holcomb JB, Iorio A, Jensen DM, Key NS, Levy JH, Mayer SA, Moore EE, Stanworth SJ, Lewis RJ, Steiner ME | 2021 | J Trauma Acute Care Surg | View Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference | Researchers | Benchmarking and standard setting |
ResearchUnit: Treating bleeding during cardiac surgery: Is prothrombin complex concentrate a substitute for plasma? | Kron A | 2021 | Blood.ca website | View ResearchUnit: Treating bleeding during cardiac surgery: Is prothrombin complex concentrate a substitute for plasma? | Health care providers | Clinical research |
The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation | Halpenny M, William N, Elmoazzen H, Giulivi A, Martin L, Perron D, Bredeson C, Hamelin L, Huebsch L, Yang L, Birch P, Acker JP | 2021 | Cytotherapy | View The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation | Blood operators | New or improved product or process |
Treatment-induced cerebral sinus venous thrombosis in childhood acute lymphoblastic malignancies: New risk factors to consider | El-Khoury H, Saifi O, Haddad S, Chahrour M, Ghanem KM, Mubarak Y, Tamim H, Makki M, Zakka C, Chan AK, Mahfouz R, Tarek N, El-Solh H, Abboud MR, Saab R, Muwakkit SA | 2021 | Pediatr Blood Cancer | View Treatment-induced cerebral sinus venous thrombosis in childhood acute lymphoblastic malignancies: New risk factors to consider | Health care providers | Clinical research |
Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals | Bulmer T, Volders D, Blake J, Kamal N | 2021 | Front Neurol | View Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals | Researchers | New or improved product or process |
Extensive variability in platelet, bleeding, and QOL outcome measures in adult and pediatric ITP: Communication from the ISTH SSC subcommittee on platelet immunology | Al-Samkari H, Cronin A, Arnold DM, Rodeghiero F, Grace RF | 2021 | J Thromb Haemost | View Extensive variability in platelet, bleeding, and QOL outcome measures in adult and pediatric ITP: Communication from the ISTH SSC subcommittee on platelet immunology | Health care providers | Benchmarking and standard setting |
Filariasis and transfusion-associated risk: a literature review | Drews SJ, Spencer BR, Wendel S, Bloch EM, International Society of Blood Transfusion TTID Working Party Parasite Subgroup | 2021 | Vox Sang | View Filariasis and transfusion-associated risk: a literature review | Health care providers | Clinical research |
Stepping Stones or Second Class Donors?: a qualitative analysis of gay, bisexual, and queer men's perspectives on plasma donation policy in Canada | Grace D, Gaspar M, Klassen B, Lessard D, Anand P, Brennan DJ, Lachowsky N, Adam BD, Cox J, Lambert G, Jollimore J, Hart TA | 2021 | BMC Public Health | View Stepping Stones or Second Class Donors?: a qualitative analysis of gay, bisexual, and queer men's perspectives on plasma donation policy in Canada | Blood operators | MSM research |
Vox Sanguinis International Forum on Mitigation Strategies to Prevent Faint and Pre-faint Adverse Reactions in Whole Blood Donors: Summary | Goldman M, Townsend M, Magnussen K, Lozano M, Nissen-Meyer LS, Lee CK, Leung JN, Takanashi M, McKay J, Kvist M, Robitaille N, Deschênes J, Di Angelantonio E, McMahon A, Roberts D, Maghsudlu M, Castrén J, Tiberghien P, Woimant G, Morel P, Kamel H, Bravo M, Shinhar E, Gendelman V, Raz H, Wendel S, Fachini R, Quee F, van den Hurk K, Wiersum J, Grima K, Speedy J, Bruun M, Dunbar N | 2021 | Vox Sang | View Vox Sanguinis International Forum on Mitigation Strategies to Prevent Faint and Pre-faint Adverse Reactions in Whole Blood Donors: Summary | Health care providers | Benchmarking and standard setting |
Effect of cryopreservation on a rare McLeod donor red blood cell concentrate | Turner TR, Clarke G, Denomme GA, Skeate R, Acker JP | 2021 | Immunohematology | View Effect of cryopreservation on a rare McLeod donor red blood cell concentrate | Researchers | Basic research |
A multisite study of pertussis vaccine effectiveness by time since last vaccine dose from three Canadian provinces: A Canadian Immunization Research Network study | Savage RD, Bell CA, Righolt CH, Wilkinson K, Schwartz KL, Chen C, Bolotin S, Deeks SL, Drews SJ, Jamieson FB, Johnson C, Kwong JC, Mahmud SM, Russell ML, Simmonds KA, Svenson LW, Crowcroft NS | 2021 | Vaccine | View A multisite study of pertussis vaccine effectiveness by time since last vaccine dose from three Canadian provinces: A Canadian Immunization Research Network study | Researchers | Clinical research |
ResearchUnit: Convalescent plasma is an ineffective treatment for patients with COVID-19 | Modi D | 2021 | Blood.ca website | View ResearchUnit: Convalescent plasma is an ineffective treatment for patients with COVID-19 | Health care providers | Clinical research |
GPIb? is the driving force of hepatic thrombopoietin generation | Karakas D, Xu M, Ni H | 2021 | Res Pract Thromb Haem | View GPIb? is the driving force of hepatic thrombopoietin generation | Researchers | Basic research |
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia | Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Völker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou EX, Rangaswamy C, Mailer RK, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin TE, Renné T | 2021 | Blood | View Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia | Researchers | Basic research |
The Virulence of S. marcescens Strains Isolated From Contaminated Blood Products Is Divergent in the C. elegans Infection Model | Diamandas A, Razon MR, Ramirez-Arcos S, Brassinga AKC | 2021 | Front Genet | View The Virulence of S. marcescens Strains Isolated From Contaminated Blood Products Is Divergent in the C. elegans Infection Model | Researchers | Basic research |
Hypothermic storage of leukoreduced red blood cells for greater than 21-days is a safe alternative to irradiation | Mykhailova O, Turner TR, Olafson C, Howell A, Nahirniak SN, Wizniak J, Gerges HYN, Baldwin T, Clarke G, Acker JP | 2021 | Transfusion | View Hypothermic storage of leukoreduced red blood cells for greater than 21-days is a safe alternative to irradiation | Researchers | New or improved product or process |
Multicenter observational study evaluating the impact of platelet transport bags on product wastage | Kron A, Vijenthira S, Pendergrast J, Modi D, McLaren A, MacDonald A, Armali C, Cserti-Gazdewich C, Smith E, Quest G, Gabanowicz K, Lieberman L, Aseltine L, Sani L, Roche M, DeOliviera M, Yu P, Fazari S, Patel S, Lin Y, Kelly Z, Callum J | 2021 | Transfusion | View Multicenter observational study evaluating the impact of platelet transport bags on product wastage | Researchers | New or improved product or process |
Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study | Stimec J, Dover S, Pullenayegum E, Blanchette VS, Doria AS, Feldman BM, Carcao M, Rivard GE, Israels SJ, Chan AK, Steele M, Cloutier S, Klaassen RJ, Price VE, Sinha R, Laferriere N, Paradis E, Wu JKM, Babyn P | 2021 | Res Pract Thromb Haemost | View Magnetic resonance imaging in boys with severe hemophilia A: Serial and end-of-study findings from the Canadian Hemophilia Primary Prophylaxis Study | Researchers | Clinical research |
Ex vivo hemostatic and immuno-inflammatory profiles of freeze-dried plasma | Peng HT, Rhind SG, Devine D, Jenkins C, Beckett A | 2021 | Transfusion | View Ex vivo hemostatic and immuno-inflammatory profiles of freeze-dried plasma | Researchers | Clinical research |
Research Unit: A more accurate and efficient way to manage blood demand and supply | Li N | 2021 | Blood.ca website | View Research Unit: A more accurate and efficient way to manage blood demand and supply | Health care providers | New or improved product or process |
Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia | Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I | 2021 | Nature | View Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia | Researchers | Clinical research |
Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography | Chung J, Stevic I, Gantioqui J, Atkinson H, Chan AKC, Chan HHW | 2021 | Blood Coagul Fibrinolysis | View Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography | Researchers | Clinical research |
The association of prothrombin complex concentrates with postoperative outcomes in cardiac surgery: an observational substudy of the FIBRES randomized controlled trial | Bartoszko J, Callum J, Karkouti K | 2021 | Can J Anaesth | View The association of prothrombin complex concentrates with postoperative outcomes in cardiac surgery: an observational substudy of the FIBRES randomized controlled trial | Researchers | Clinical research |
Administration de produits sanguins | O'Reilly C | 2021 | Guide de la pratique transfusionnelle | View Administration de produits sanguins | Health care providers | Benchmarking and standard setting |
The Monocyte Monolayer Assay to Build a Personalized Pipeline of Transfusion Support in Highly Sensitized Sickle Cell Disease | Vijenthira S, Nguyen J, Branch DR, Clarke G, Ward R, Saeed S, Cserti-Gazdewich C | 2021 | Blood | View The Monocyte Monolayer Assay to Build a Personalized Pipeline of Transfusion Support in Highly Sensitized Sickle Cell Disease | Health care providers | New or improved product or process |
Digital Microfluidic Hemagglutination Assays for Blood Typing, Donor Compatibility Testing, and Hematocrit Analysis | Sklavounos AA, Lamanna J, Modi D, Gupta S, Mariakakis A, Callum J, Wheeler AR | 2021 | Clin Chem | View Digital Microfluidic Hemagglutination Assays for Blood Typing, Donor Compatibility Testing, and Hematocrit Analysis | Researchers | New or improved product or process |
The estimated risk of SARS-CoV- 2 infection via cornea transplant in Canada | O’Brien SF, Lewin A, Yi Q-L, Dowling G, Fissette E, Drews SJ | 2021 | Cell Tissue Bank | View The estimated risk of SARS-CoV- 2 infection via cornea transplant in Canada | Health care providers | Clinical research |
Stuttering priapism in a patient with sickle cell trait treated with automated red cell exchange transfusion | Ebraheem MS, Verhovsek M | 2021 | Blood Adv | View Stuttering priapism in a patient with sickle cell trait treated with automated red cell exchange transfusion | Health care providers | Clinical research |
International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses | Al-Riyami AZ, Burnouf T, Yazer M, Triulzi D, Kuma? LT, Sa?dur L, Pelit NB, Bazin R, Hindawi SI, Badawi MA, Patidar GK, Pandey HC, Chaurasia R, Fachini RM, Scuracchio P, Wendel S, Ang AL, Ong KH, Young P, Ihalainen J, Vierikko A, Qiu Y, Yang R, Xu H, Rahimi-Levene N, Shinar E, Izak M, Gonzalez CA, Ferrari DM, Cini PV, Aditya RN, Sharma RR, Sachdev S, Hans R, Lamba DS, Nissen-Meyer LSH, Devine DV, Lee CK, Leung JN-S, Hung IFN, Tiberghien P, Gallian P, Morel P, Al Maamari K, Al-Hinai Z, Vrielink H, So-Osman C, De Angelis V, Berti P, Ostuni A, Marano G, Nevessignsky MT, El Ekiaby M, Daly J, Hoad V, Kim S, van den Berg K, Vermeulen M, Glatt TN, Schäfer R, Reik R, Gammon R, Lopez M, Estcourt L, MacLennan S, Roberts D, Louw V, Dunbar N | 2021 | Vox Sang | View International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses | Researchers | Clinical research |
Frequency and timing of all-cause deaths in visits involving suspected transfusion reactions, and the significance of cardiopulmonary disturbances | McVey MJ, Cohen R, Arsenault V, Escorcia A, Tasmin F, Pendergrast J, Lieberman L, Lin Y, Callum J, Cserti-Gazdewich C | 2021 | Vox Sang | View Frequency and timing of all-cause deaths in visits involving suspected transfusion reactions, and the significance of cardiopulmonary disturbances | Health care providers | Clinical research |
Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant | Hamada M, Bhakta V, Andres SN, Sheffield WP | 2021 | Front Cardiovasc Med | View Stepwise Reversion of Multiply Mutated Recombinant Antitrypsin Reveals a Selective Inhibitor of Coagulation Factor XIa as Active as the M358R Variant | Researchers | Basic research |
International Forum on Walking Blood Bank Programmes: Responses | Martinaud C, Scorer T, Lozano M, Miles A, Fitchett G, Ba A, Wikman A, Nimberger-Hansson P, Enbuske S, Bohon?k M, Devine D, Beckett AN, Mbanya D, T'Sas F, Degueldre J, Chueca M, Dedome E, Apelseth T, Strandenes G, Wendel S, Fachini R, Olszewski A, Dupont C, Glassberg E, Shinar E, Taylor AL, Corley JB, Nadarajan VS, Dunbar N | 2021 | Vox Sang | View International Forum on Walking Blood Bank Programmes: Responses | Blood operators | New or improved product or process |
Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells | Karakas D, Li J, Ni H | 2021 | Blood | View Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells | Researchers | Basic research |
Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein | Greinacher A, Selleng K, Mayerle J, Palankar R, Wesche J, Reiche S, Aebischer A, Warkentin TE, Muenchhoff M, Hellmuth JC, Keppler OT, Duerschmied D, Lother A, Rieg S, Gawaz MP, Mueller KAL, Scheer CS, Napp M, Hahnenkamp K, Lucchese G, Vogelgesang A, Flöel A, Lovreglio P, Stufano A, Marschalek R, Thiele T | 2021 | Blood | View Anti-platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein | Researchers | Clinical research |
Buffy coat platelets coming to America: Are we ready? | Gammon RR, Devine D, Katz LM, Quinley E, Wu Y, Rowe K, Razatos A, Min K, Reichenberg S, Smith R | 2021 | Transfusion | View Buffy coat platelets coming to America: Are we ready? | Blood operators | New or improved product or process |
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials | Lawati KA, Sharif S, Maqbali SA, Rimawi HA, Petrosoniak A, Belley-Cote EP, Sharma SV, Morgenstern J, Fernando SM, Owen JJ, Zeller M, Quinlan D, Alhazzani W, Rochwerg B | 2021 | Intensive Care Med | Researchers | Clinical research | |
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis | Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP | 2021 | Sci Rep | View Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis | Researchers | Basic research |