Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Risk-based decision making in transfusion medicine Leach Bennett J, Devine DV 2018 Vox Sang View Researchers New or improved product or process
Human T-cell lymphotropic virus: A simulation model to estimate residual risk with universal leucoreduction and testing strategies in Canada O'Brien SF, Yi Q-L, Goldman M, Grégoire Y, Delage G 2018 Vox Sang View Researchers New or improved product or process
Healthcare provider knowledge, attitudes, beliefs, and practices surrounding the prescription of opioids for chronic non-cancer pain in North America: protocol for a mixed-method systematic review Rash JA, Buckley N, Busse JW, Campbell TS, Corace K, Cooper L, Flusk D, Iorio A, Lavoie KL, Poulin PA, Skidmore B 2018 Systematic Reviews View Researchers Clinical research
Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets Ni R, Neves MAD, Wu C, Cerroni SE, Flick MJ, Ni H, Weitz JI, Gross PL, Kim PY 2020 Thromb Haemost View Researchers Basic research
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM 2020 Haemophilia View Researchers Clinical research
Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study Alabdullatif M, Osman IE, Alrasheed M, Ramirez-Arcos S, Alyousef M, Althawadi S, Alhumiadan H 2021 Transfusion View Researchers New or improved product or process
Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP Khan R, Menard M, Jen C-C, Chen X, Norris PAA, Lazarus AH 2020 Blood View Researchers Basic research
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC 2020 Sci Immunol View Researchers Clinical research
A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M 2021 Transfusion View Researchers Basic research
T cell-mediated autoimmunity in immune thrombocytopenia Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM 2022 Eur J Haematol View Researchers Clinical research
Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference Spinella PC, El Kassar N, Cap AP, Kindzelski AL, Almond CS, Barkun A, Gernsheimer TB, Goldstein JN, Holcomb JB, Iorio A, Jensen DM, Key NS, Levy JH, Mayer SA, Moore EE, Stanworth SJ, Lewis RJ, Steiner ME 2021 J Trauma Acute Care Surg View Researchers Benchmarking and standard setting
Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals Bulmer T, Volders D, Blake J, Kamal N 2021 Front Neurol View Researchers New or improved product or process
Impact of cardiopulmonary bypass duration on efficacy of fibrinogen replacement with cryoprecipitate compared with fibrinogen concentrate: a <em>post hoc</em> analysis of the Fibrinogen Replenishment in Surgery (FIBRES) randomised controlled trial Bartoszko J, Martinez-Perez S, Callum J, Karkouti K, Farouh ME, Scales DC, Heddle NM, Crowther M, Rao V, Hucke H-P, Carroll J, Grewal D, Brar S, Brussières J, Grocott H, Harle C, Pavenski K, Rochon A, Saha T, Shepherd L, Syed S, Tran D, Wong D, Zeller M 2022 Br J Anaesth View Researchers Clinical research
Evaluation of the performance of multiple immunoassay diagnostic platforms on the National Microbiology Laboratory SARS-CoV-2 National Serology Panel Dibernardo A, Toledo NP, Robinson A, Osiowy C, Giles E, Day J, Lindsay LR, Drebot MA, Booth TF, Pidduck T, Baily A, Charlton CL, Tipples G, Kanji JN, Brochu G, Lang A, Therrien C, Bélanger-Collard M, Beaulac S-N, Gilfix BM, Boivin G, Hamelin M-È, Carbonneau J, Lévesque S, Martin P, Finzi A, Gendron-Lepage G, Goyette G, Benlarbi M, Gasser R, Fortin C, Martel-Lafferrière V, Lavoie M, Guérin R, Haraoui L-P, Renaud C, Jenkins C, O'Brien SF, Drews SJ, Conrod V, Tran V, Awrey B, Scheuermann R, DuPuis A, Payne A, Warszycki C, Girardin R, Lee W, Zahariadis G, Jiao L, Needle R, Cordenbach J, Zaharatos J, Taylor K, Teltscher M, Miller M, Elsherif M, Robertson P, Robinson JL 2022 J Assoc Med Microbiol Infect Dis Can View Researchers Benchmarking and standard setting
The bending rigidity of the red blood cell cytoplasmic membrane Himbert S, D’Alessandro A, Qadri SM, Majcher MJ, Hoare T, Sheffield WP, Nagao M, Nagle JF, Rheinstädter MC 2022 PLoS One View Researchers Basic research
Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study Leong DP, Zhang A, Breznik JA, Clare R, Huynh A, Mushtaha M, Rangarajan S, Stacey H, Kim PY, Loeb M, Denburg JA, Mertz D, Chagla Z, Nazy I, Miller MS, Bowdish DME, Duong M 2023 PLoS One View Researchers Clinical research
An evaluation of overall effectiveness and treatment satisfaction with intravenous immunoglobulin among patients with immune thrombocytopenia Sholapur NS, Hamilton K, Butler L, Heddle NM, Arnold DM 2016 Transfusion View Researchers Clinical research
Assessment of antibody-based drugs effects on murine bone marrow and peritoneal macrophage activation Kozicky L, Sly LM 2017 J Vis Exp View Researchers Basic research
CD44 antibody-mediated amelioration of murine immune thrombocytopenia (ITP): mouse background determines the effect of FcgammaRIIb genetic disruption Crow AR, Amash A, Lazarus AH 2014 Transfusion View Researchers Basic research
Cryopreservation of adult unrelated donor products in hematopoietic cell transplantation: the OneMatch experience and systematic review of the literature Aziz J, Morris G, Rizk M, Shorr R, Mercer D, Young K, Allan D 2017 Transfusion View Researchers Clinical research
Development of a proof of principle for universal neutralization of antibiotics in cord blood by-products used for sterility testing Kou Y, Halpenny M, Elmoazzen H, Ramirez-Arcos S 2018 Transfusion View Researchers New or improved product or process
Enhancement of biological reactions on cell surfaces via macromolecular crowding Chapanian R, Kwan DH, Constantinescu I, Shaikh FA, Rossi NA, Withers SG, Kizhakkedathu JN 2014 Nat Commun View Researchers Basic research
High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis Mithoowani S, Gregory-Miller K, Goy J, Miller MC, Wang G, Noroozi N, Kelton JG, Arnold DM 2016 Lancet Haematol View Researchers Clinical research
Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy Wang D, Shanina I, Toyofuku WM, Horwitz MS, Scott MD 2015 PLoS One View Researchers Basic research
Label-free and noninvasive optical detection of the distribution of nanometer-size mitochondria in single cells Su X, Qiu Y, Marquez-Curtis L, Gupta M, Capjack CE, Rozmus W, Janowska-Wieczorek A, Tsui YY 2011 J Biomed Opt View Researchers New or improved product or process
Performance characteristics of an automated latex immunoturbidimetric assay [HemosIL HIT-Ab(PF4-H)] for the diagnosis of immune heparin-induced thrombocytopenia Warkentin TE, Sheppard J-AI, Linkins L-A, Arnold DM, Nazy I 2017 Thromb Res View Researchers Clinical research
Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions Hume HA, Ddungu H, Angom R, Baluku H, Kajumbula H, Kyeyune-Byabazaire D, Orem J, Ramirez-Arcos S, Tobian AA 2016 Transfusion View Researchers Basic research
Prevention of Thrombogenesis from Whole Human Blood on Plastic Polymer by Ultrathin Monoethylene Glycol Silane Adlayer Fedorov K, Blaszykowski C, Sheikh S, Reheman A, Romaschin A, Ni H, Thompson M 2014 Langmuir View Researchers Basic research
Rapid removal of glycerol from frozen-thawed red blood cells Lusianti RE, Benson JD, Acker JP, Higgins AZ 2013 Biotechnol Prog View Researchers New or improved product or process
Stability of Thawed Apheresis Fresh-Frozen Plasma Stored for up to 120 Hours at 1° C to 6° C Sheffield WP, Bhakta V, Yi Q-L, Jenkins C 2016 J Blood Transfus View Researchers Basic research
Temperature stability of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] in the form of a solution or in the lyophilized form during storage at -80°C, 4°C, 25°C and 37°C or pasteurization at 70°C Bian Y, Guo C, Chang T 2016 Artif Cells Nanomed Biotechnol View Researchers Basic research
Closing in on DEHP-free red blood cell concentrate containers Almizraq RJ, Acker J 2018 Transfusion View Researchers New or improved product or process
Devices to Reduce the Volume of Blood Taken for Laboratory Testing in ICU Patients: A Systematic Review Siegal DM, Manning N, Jackson Chornenki NL, Hillis CM, Heddle NM 2018 J Intensive Care Med View Researchers New or improved product or process
Coenzyme Q10 attenuates platelet integrin alpha II beta 3 signaling and platelet hyper-reactivity in ApoE-deficient mice Ya F, Xu XR, Tian Z, Gallant RC, Song F, Shi Y, Wu Y, Wan J, Zhao Y, Adili R, Ling W, Ni H, Yang Y 2020 Food Funct View Researchers Basic research
Fc?RI and FC?RIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/III autoantibody-opsonized platelets in immune thrombocytopenia Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH 2020 Haematologica View Researchers Basic research
Proceedings of the Food and Drug Administration public workshop on pathogen reduction technologies for blood safety 2018 Atreya C, Glynn S, Busch M, Kleinman S, Snyder E, Rutter S, AuBuchon J, Flegel W, Reeve D, Devine D, Cohn C, Custer B, Goodrich R, Benjamin RJ, Razatos A, Cancelas J, Wagner S, Maclean M, Gelderman M, Cap A, Ness P 2019 Transfusion View Researchers New or improved product or process
Assessment of extracellular vesicles using IFC for application in transfusion medicine Mykhailova O, Seghatchian J, Acker JP 2020 Transfus Apher Sci View Researchers Basic research
Clinical use of Convalescent Plasma in the COVID-19 pandemic: a transfusion-focussed gap analysis with recommendations for future research priorities Al-Riyami AZ, Schäfer R, van den Berg K, Bloch EM, Estcourt LJ, Goel R, Hindawi S, Josephson CD, Land K, McQuilten ZK, Spitalnik SL, Wood EM, Devine DV, So-Osman C 2020 Vox Sang View Researchers Clinical research
Effect of cryopreservation on a rare McLeod donor red blood cell concentrate Turner TR, Clarke G, Denomme GA, Skeate R, Acker JP 2021 Immunohematology View Researchers Basic research
A multisite study of pertussis vaccine effectiveness by time since last vaccine dose from three Canadian provinces: A Canadian Immunization Research Network study Savage RD, Bell CA, Righolt CH, Wilkinson K, Schwartz KL, Chen C, Bolotin S, Deeks SL, Drews SJ, Jamieson FB, Johnson C, Kwong JC, Mahmud SM, Russell ML, Simmonds KA, Svenson LW, Crowcroft NS 2021 Vaccine View Researchers Clinical research
GPIb? is the driving force of hepatic thrombopoietin generation Karakas D, Xu M, Ni H 2021 Res Pract Thromb Haem View Researchers Basic research
Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Völker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou EX, Rangaswamy C, Mailer RK, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin TE, Renné T 2021 Blood View Researchers Basic research
The Virulence of S. marcescens Strains Isolated From Contaminated Blood Products Is Divergent in the C. elegans Infection Model Diamandas A, Razon MR, Ramirez-Arcos S, Brassinga AKC 2021 Front Genet View Researchers Basic research
von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient-derived endothelial colony-forming cells Bowman M, Casey L, Selvam SN, Lima PDA, Rawley O, Hinds M, Tuttle A, Grabell J, Iorio A, Walker I, Lillicrap D, James P 2022 J Thromb Haemost View Researchers Basic research
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia Gabe C, Liu Y, Duncan J, St John M, Lucier KJ, Kimmel D, Kelton JG, Arnold DM 2023 Platelets View Researchers Clinical research
A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus McCarthy SDS, Majchrzak-Kita B, Racine T, Kozlowski HN, Baker DP, Hoenen T, Kobinger GP, Fish EN, Branch DR 2016 PLoS Negl Trop Dis View Researchers Basic research
Anthocyanin Extract from Black Rice Significantly Ameliorates Platelet Hyperactivity and Hypertriglyceridemia in Dyslipidemic Rats Induced by High Fat Diets Yang Y, Andrews MC, Hu Y, Wang D, Qin Y, Zhu Y, Ni H, Ling W 2011 J Agric Food Chem View Researchers Basic research
Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity? Gierczak RF, Bhakta V, Xie M, Sheffield WP 2015 J Biotechnol View Researchers Basic research
Deformability based sorting of red blood cells improves diagnostic sensitivity for malaria caused by Plasmodium falciparum Guo Q, Duffy SP, Matthews K, Deng X, Santoso AT, Islamzada E, Ma H 2016 Lab Chip View Researchers New or improved product or process
Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin ?-chain crosslinking Byrnes JR, Duval C, Wang Y, Hansen CE, Ahn B, Mooberry MJ, Clark MA, Johnsen JM, Lord ST, Lam W, Meijers JCM, Ni H, Ariens RAS, Wolberg AS 2015 Blood View Researchers Basic research