Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Immunity against a therapeutic xenoprotein/Fc construct delivered by gene transfer is reduced through binding to the inhibitory receptor Fc?RIIb Liang Y, Qiu H, Glinka Y, Lazarus AH, Ni H, Prud'homme GJ, Wang Q 2011 J Gene Med View Researchers Basic research
In vivo clearance of alpha-1 acid glycoprotein is influenced by the extent of its N-linked glycosylation and by its interaction with the vessel wall McCurdy TR, Bhakta V, Eltringham-Smith LJ, Gataiance S, Fox-Robichaud AE, Sheffield WP 2012 J Biomed Biotechnol View Researchers Basic research
Rationale and design of platelet transfusions in haematopoietic stem cell transplantation: the PATH pilot study Tay J, Allan D, Beattie S, Bredeson C, Fergusson D, Maze D, Sabloff M, Thavorn K, Tinmouth A 2016 BMJ Open View Researchers Clinical research
The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia Arnold DM, Lauzier F, Albert M, Williamson D, Li N, Zarychanski R, Doig C, McIntyre L, Freitag A, Crowther M, Saunders L, Clarke F, Bellomo R, Qushmaq I, Lopes R, Heels-Ansdell D, Webert K, Cook D 2017 Res Pract Thromb Haemost View Researchers Clinical research
The Ins and Outs of Hematopoietic Stem Cells: Studies to Improve Transplantation Outcomes Marquez-Curtis LA, Turner AR, Sridharan S, Ratajczak MZ, Janowska-Wieczorek A 2011 Stem Cell Rev View Researchers Basic research
Value of MMA crossmatch? Tong TN, Cserti-Gazdewich CM, Branch DR 2016 Transfus Med View Researchers Basic research
Peri-Operative Eltrombopag or Immune Globulin for Patients with Immune Thrombocytopaenia (The Bridging ITP Trial): Methods and Rationale Arnold D, Jamula E, Heddle N, Cook R, Hsia C, Sholzberg M, Lin Y, Kassis J, Blostein M, Larratt L, Amini S, Schipperus M, Carruthers J, Lane S, Li N, G. Kelton J 2019 Thromb Haemost View Researchers Clinical research
International survey on the impact of parasitic infections: frequency of transmission and current mitigation strategies Leiby DA, O'Brien SF, Wendel S, Nguyen ML, Delage G, Devare SG, Hardiman A, Nakhasi HL, Sauleda S, Bloch EM, WPTTID Subgroup on Parasites 2019 Vox Sang View Researchers Clinical research
Thermal expansion of substrate may affect adhesion of Chinese hamster fibroblasts to surfaces during freezing Rutt T, Eskandari N, Zhurova M, Elliott JAW, McGann LE, Acker JP, Nychka JA 2019 Cryobiology View Researchers Basic research
Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay Warkentin TE, Arnold DM, Kelton JG, Sheppard J-AI, Smith JW, Nazy I 2018 Chest View Researchers Basic research
The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses Mendonca A, Rahman MS, Alhalawani A, Rodriguez O, Gallant RC, Ni H, Clarkin OM, Towler MR 2019 J Biomed Mater Res Part B Appl Biomater View Researchers Basic research
International Forum on Occult hepatitis B infection and transfusion safety Seed CR, Allain J-P, Lozano M, Laperche S, Gallian P, Gross S, Kwon S-Y, Oh EY, Kim JN, Chua SS, Lam S, Ang AL, Tsoi W-C, Hewitt PE, Davison KL, Tettmar K, O'Flaherty N, Boland F, Williams P, Pomeroy L, Wendel S, Fachini R, Scuracchio P, Carminato P, Fearon M, O'Brien SF, Delage G, Kiely P, Hoad V, Matsubayashi K, Satake M, Taira R, Stramer SL, Sauleda S, Bes M, Piron M, El Ekiaby M, Vermeulen M, Levi?nik Stezinar S, Nograšek P, Jarvis LM, Petrik J, Charlewood R, Flanagan P, Grabarczyk P, Kopacz A, ??towska M, Seifried E, Schmidt M 2019 Vox Sang View Researchers Benchmarking and standard setting
Platelet physiology and immunology: pathogenesis and treatment of classical and non-classical fetal and neonatal alloimmune thrombocytopenia Chen ZY, Oswald BE, Sullivan JA, Dahmani FZ, Pasman Y, Liu Z, Chen P, Ni H 2019 Ann Blood View Researchers Basic research
The systematic use of evidence-based methodologies and technologies enhances shared decision-making in the 2018 International Consensus Conference on Patient Blood Management Van Remoortel H, Aranko K, Mueller MM, De Buck E, Devine D, Folléa G, Meybohm P, Tiberghien P, Wood EM, Vandekerckhove P, Seifried E 2020 Vox Sang View Researchers Benchmarking and standard setting
Age-Specific SARS-CoV-2 Infection Fatality and Case Identification Fraction in Ontario, Canada Fisman DN, Drews SJ, Tuite AR, O’Brien SF 2020 medRxiv View Researchers Clinical research
Characterizing the ability of an ice recrystallization inhibitor to improve platelet cryopreservation Waters L, Ben R, Acker JP, Padula MP, Marks DC, Johnson L 2020 Cryobiology View Researchers New or improved product or process
Crosstalk Between Platelets and Microbial Pathogens Li C, Li J, Ni H 2020 Front Immunol View Researchers Basic research
Evidence for sustained mucosal and systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yun YF, Marin LG, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, J.McGeer A, Gommerman JL, Gingras A-C 2020 medRxiv View Researchers Basic research
Safety and efficacy of self-administered romiplostim in patients with immune thrombocytopenia: Results of an integrated database of five clinical trials Kuter DJ, Arnold DM, Rodeghiero F, Janssens A, Selleslag D, Bird R, Newland A, Mayer J, Wang K, Olie R 2020 Am J Hematol View Researchers Clinical research
Psychometric Evaluation of ITP Life Quality Index (ILQI) in a Global Survey of Patients with Immune Thrombocytopenia Viana R, D'Alessio D, Grant L, Cooper N, Arnold D, Morgan M, Provan D, Cuker A, Hill QA, Tomiyama Y, Ghanima W 2021 Adv Ther View Researchers Clinical research
Risk of transfusion-transmitted Babesia microti in Canada O'Brien SF, Drews SJ, Yi Q-L, Bloch EM, Ogden NH, Koffi JK, Lindsay LR, Gregoire Y, Delage G 2021 Transfusion View Researchers Benchmarking and standard setting
Effect of modern infusion pumps on RBC quality Hadjesfandiari N, Serrano K, Levin E, Johal P, Feenstra S, Shih AW, Devine DV 2022 Transfusion View Researchers Benchmarking and standard setting
Monocyte monolayer assay predictions of clinical outcome for serologically incompatible red blood cells is all about timing Branch DR, Sandhu G, Raos M 2021 Transfusion View Researchers New or improved product or process
The clinical and laboratory diagnosis of vaccine-induced immune thrombotic thrombocytopenia Bissola AL, Daka M, Arnold DM, Smith JW, Moore JC, Clare R, Ivetic N, Kelton JG, Nazy I 2022 Blood Adv View Researchers Clinical research
Understanding the experiences of plasma donors in Canada's new source plasma collection centres during COVID-19: A qualitative study Holloway K 2022 Vox Sang View Researchers Ethical, legal & social implications research
c-Mpl-del, a c-Mpl alternative splicing isoform, promotes AMKL progression and chemoresistance Li F, Xiong Y, Yang M, Chen P, Zhang J, Wang Q, Xu M, Wang Y, He Z, Zhao X, Huang J, Gu X, Zhang L, Sun R, Sun X, Li J, Ou J, Xu T, Huang X, Cao Y, Xu XR, Karakas D, Li J, Ni H, Zhang Q 2022 Cell Death Dis View Researchers Basic research
Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics Nummi V, Lehtinen AE, Iorio A, Szanto T, Lassila R 2022 Haemophilia View Researchers Clinical research
Changing Patterns of SARS-CoV-2 Seroprevalence among Canadian Blood Donors during the Vaccine Era Reedman CN, Drews SJ, Yi Q-L, Pambrun C, O’Brien SF 2022 Microbiol Spectr View Researchers Clinical research
A novel nanobiotherapeutic poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] with no cardiac toxicity for the resuscitation of a rat model with 90 minutes of sustained severe hemorrhagic shock with loss of 2/3 blood volume Bian Y, Chang TM 2015 Artif Cells Nanomed Biotechnol View Researchers Basic research
CD8+ T cells are predominantly protective and required for effective steroid therapy in murine models of immune thrombocytopenia Ma L, Simpson E, Li J, Xuan M, Xu M, Baker L, Shi Y, Yougbaré I, Wang X, Zhu G, Chen P, Prudhomme GJ, Lazarus AH, Freedman J, Ni H 2015 Blood View Researchers Basic research
Coinfusion of dextrose-containing fluids and red blood cells does not adversely affect in vitro red blood cell quality Keir AK, Hansen AL, Callum J, Jankov RP, Acker JP 2014 Transfusion View Researchers New or improved product or process
c-SRC protein tyrosine kinase regulates early HIV-1 infection post-entry McCarthy SDS, Sakac D, Neschadim A, Branch DR 2016 AIDS View Researchers Basic research
Development of antifouling and bactericidal coatings for platelet storage bags using dopamine chemistry Hadjesfandiari N, Weinhart M, Kizhakkedathu JN, Haag R, Brooks DE 2018 Adv Healthc Mater View Researchers New or improved product or process
Eadie-Hofstee analysis of red blood cell deformability Stadnick H, Onell R, Acker JP, Holovati JL 2011 Clin Hemorheol Microcirc View Researchers Basic research
Enhancing the Migration Ability of Mesenchymal Stromal Cells by Targeting the SDF-1/CXCR4 Axis Marquez-Curtis LA, Janowska-Wieczorek A 2013 BioMed Res Int View Researchers Basic research
From cytokines to pragmatic designs: changing paradigms Heddle NM 2017 Transfusion View Researchers Clinical research
Hope for the Best, but Prepare for the Worst Blake J, Nemergut EC 2014 Anesth Analg View Researchers New or improved product or process
Impact of blood manufacturing and donor characteristics on membrane water permeability and in vitro quality parameters during hypothermic storage of red blood cells Alshalani A, Howell A, Acker JP 2018 Cryobiology View Researchers Basic research
Innate and adaptive immunity in immune thrombocytopenia Lazarus AH, Semple JW, Cines DB 2013 Semin Hematol View Researchers Clinical research
Laboratory management of perinatal patients with apparently "new" anti-D Hannon J, Clarke G 2016 Immunohematology View Researchers Basic research
Mechanistic properties of intravenous immunoglobulin in murine immune thrombocytopenia: support for Fc?RIIB falls by the wayside Crow AR, Lazarus AH 2016 Semin Hematol View Researchers Basic research
O-aryl-glycoside ice recrystallization inhibitors as novel cryoprotectants: A structure-function study Capicciotti CJ, Mancini RS, Turner TR, Koyama T, Alteen MG, Doshi M, Inada T, Acker JP, Ben RN 2016 ACS Omega View Researchers Basic research
Plant food delphinidin-3-glucoside significantly inhibits platelet activation and thrombosis: novel protective roles against cardiovascular diseases Yang Y, Shi Z, Reheman A, Jin JW, Li C, Wang Y, Andrews MC, Chen P, Zhu G, Ling W, Ni H 2012 PLoS One View Researchers Basic research
Polymer brush-based approaches for the development of infection-resistant surfaces Hadjesfandiari N, Yu K, Mei Y, Kizhakkedathu JN 2014 J Mater Chem B Mater Biol Med View Researchers Basic research
Proteome changes in platelets after pathogen inactivation - an interlaboratory consensus Prudent M, D'Alessandro A, Cazenave JP, Devine DV, Gachet C, Greinacher A, Lion N, Schubert P, Steil L, Thiele T, Tissot J-D, Volker U, Zolla L 2014 Transfus Med Rev View Researchers Basic research
Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol Boutin A, Chasse M, Shemilt M, Lauzier F, Moore L, Zarychanski R, Lacroix J, Fergusson DA, Desjardins P, Turgeon AF 2014 Syst Rev View Researchers Other
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E 2016 Sci Rep View Researchers Basic research
The Platelet as a physiological objection in the circulation Marshall AH, Wang Y, Reheman A, Chen P, Zhu G, Ni H 2014 Pathobiology of human disease: a dynamic encyclopedia of disease mechanisms View Researchers Basic research
Two novel ABCG2 alleles resulting in a Jr (a-) phenotype Berardi P, Cote J, Vege S, Aeschlimann J, Cserti-Gazdewich C, Westhoff CM 2017 Transfusion View Researchers Basic research
MicroRNA-218-5p Promotes Endovascular Trophoblast Differentiation and Spiral Artery Remodeling Brki J, Dunk C, O'Brien J, Fu G, Nadeem L, Wang Y-l, Rosman D, Salem M, Shynlova O, Yougbare I, Ni H, Lye SJ, Peng C 2018 Mol Ther View Researchers Basic research