Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS 2022 Cytotherapy View Researchers Clinical research
Peptide-Modified Surfaces for Binding Carbamylated Proteins from Plasma Ma Y, Hadjesfandiari N, Doschak M, Devine D, Tonelli M, Unsworth L 2021 Langmuir View Researchers Basic research
Staphylococcus epidermidis undergoes global changes in gene expression during biofilm maturation in platelet concentrates Loza-Correa M, Yousuf B, Ramirez-Arcos S 2021 Transfusion View Researchers Basic research
Soy Isoflavones Inhibit Both GPIb-IX Signaling and ?IIb?3 Outside-In Signaling via 14-3-3? in Platelet Liu M, Wang G, Xu R, Shen C, Ni H, Lai R 2021 Molecules View Researchers Basic research
Heterogeneity of Vaccine-Induced Immune Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination and Safety of Second Vaccination with BNT162b2 Lindhoff-Last E, Schoenborn L, Piorkowski M, Herold J, Greinacher A, Sheppard JA, Warkentin TE 2022 Thromb Haemost View Researchers Clinical research
What constitutes the most cautious approach for a pregnant person with weak D type 4.0? Lieberman L, Flegel W, Bodnar M, Clarke G, Hannon J 2021 CMAJ Open View Health care providers Benchmarking and standard setting
From demand forecasting to inventory ordering decisions for red blood cells through integrating machine learning, statistical modeling, and inventory optimization Li N, Arnold DM, Down DG, Barty R, Blake J, Chiang F, Courtney T, Waito M, Trifunov R, Heddle NM 2022 Transfusion View Researchers New or improved product or process
Concentré de recherche: Précision et efficacité accrues dans la gestion des réserves de sang Li N 2021 Blood.ca website View Health care providers New or improved product or process
Research Unit: A more accurate and efficient way to manage blood demand and supply Li N 2021 Blood.ca website View Health care providers New or improved product or process
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H 2021 Sci Rep View Researchers Clinical research
Mechanism of increased efficacy of recombinant Fc-?TP-L309C compared to IVIg to ameliorate mouse immune thrombocytopenia Lewis BJB, Binnington B, Blacquiere M, Spirig R, Käsermann F, Branch DR 2021 eJHaem View Researchers Basic research
An international comparison of anti-SARS-COV-2 assays used for seroprevalence surveys from blood component providers Lewin A, Drews SJ, Lieshout-Krikke R, Erikstrup C, Saeed S, Fady H, Uzicanin S, Custer B, O’Brien SF, the Surveillance Risk Assessment Policy tVS-gotI, Transfusion Transmitted Infectious Diseases Working Party 2021 Vox Sang View Blood operators Benchmarking and standard setting
Response to ‘Adverse cardiac outcomes in patients with chronic myeloid leukaemia treated with tyrosine kinase inhibitors’ Leong D, Hillis C, Aghel N, Pond G, Seow H 2021 Heart View Researchers Clinical research
Early warning and rapid public health response to prevent COVID-19 outbreaks in long-term care facilities (LTCF) by monitoring SARS-CoV-2 RNA in LTCF site-specific sewage samples and assessment of antibodies response in this population: prospective study protocol Lee BE, Sikora C, Faulder D, Risling E, Little LA, Qiu Y, Gao T, Bulat R, Craik S, Hrudey SE, Ohinmaa A, Estabrooks CA, Gingras A-C, Charlton C, Kim J, Wood H, Robinson A, Kanji JN, Zelyas N, O’Brien SF, Drews S, Pang X-L 2021 BMJ Open View Regulators New or improved product or process
Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality Leatherdale A, Stukas S, Lei V, West HE, Campbell CJ, Hoiland RL, Cooper J, Wellington CL, Sekhon MS, Pryzdial ELG, Conway EM 2022 Med Microbiol Immunol View Health care providers Clinical research
Improving Medical Education in Hematology and Transfusion Medicine in Canada: Standards and Limitations Laureano M, Mithoowani S, Tseng E, Zeller M 2021 Adv Med Educ Pract View Health care providers Benchmarking and standard setting
Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open-label study Kuter DJ, Rogers KA, Boxer MA, Choi M, Agajanian R, Arnold DM, Broome CM, Field JJ, Murakhovskaya I, Numerof R, Tong S 2022 Am J Hematol View Researchers Clinical research
Concentré de recherche: Saignement pendant la chirurgie cardiaque?: le?concentré de complexe prothrombique est-il une solution de rechange au plasma? Kron A 2021 Blood.ca website View Health care providers Clinical research
ResearchUnit: Treating bleeding during cardiac surgery: Is prothrombin complex concentrate a substitute for plasma? Kron A 2021 Blood.ca website View Health care providers Clinical research
Vaccine-induced immune thrombotic thrombocytopenia Klok FA, Pai M, Huisman MV, Makris M 2022 Lancet Haematol View Researchers Clinical research
Réactions transfusionnelles anaphylactiques et déficit en IgA Khandelwal A, Clarke G, Goldman M 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Anaphylactic transfusion reactions and IgA deficiency Khandelwal A, Clarke G, Goldman M 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Répercussions de la COVID-19 sur le don de sang au Canada Khandelwal A 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Impact of COVID-19 on blood donation in Canada Khandelwal A 2021 Blood.ca website View Health care providers Benchmarking and standard setting
Aspirin nonsensitivity in patients with vascular disease: Assessment by light transmission aggregometry (aspirin nonsensitivity in vascular patients) Khan H, Zamzam A, Gallant RC, Syed MH, Rand ML, Ni H, Forbes TL, Al-Omran M, Qadura M 2021 Res Pract Thromb Haemost View Researchers Clinical research
Plateletworks® as a Point-of-Care Test for ASA Non-Sensitivity Khan H, Jain S, Gallant RC, Syed MH, Zamzam A, Al-Omran M, Rand ML, Ni H, Abdin R, Qadura M 2021 J Pers Med View Researchers New or improved product or process
Lessons from vaccine-induced immune thrombotic thrombocytopenia Kelton JG, Arnold DM, Nazy I 2021 Nat Rev Immunol View Researchers Clinical research
Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts Kaushal R, Jahan S, McGregor C, Pineault N 2022 Cytotherapy View Researchers New or improved product or process
Cost-effectiveness of eltrombopag vs intravenous immunoglobulin for the perioperative management of immune thrombocytopenia Kaur MN, Arnold DM, Heddle NM, Cook RJ, Hsia C, Blostein M, Jamula E, Sholzberg M, Lin Y, Kassis J, Larratt L, Tinmouth A, Carruthers J, Li N, Liu Y, Xie F 2022 Blood Adv View Health care providers Clinical research
GPIb? is the driving force of hepatic thrombopoietin generation Karakas D, Xu M, Ni H 2021 Res Pract Thromb Haem View Researchers Basic research
Novel Mechanisms of Thrombopoietin Generation: The Essential Role of Kupffer Cells Karakas D, Li J, Ni H 2021 Blood View Researchers Basic research
CD248 enhances tissue factor procoagulant function, promoting arterial and venous thrombosis in mouse models Kapopara PR, Safikhan NS, Huang JL, Meixner SC, Gonzalez K, Loghmani H, Ruf W, Mast AE, Lei V, Pryzdial ELG, Conway EM 2021 J Thromb Haemost View Researchers Basic research
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup 2022 Vox Sang View Researchers Benchmarking and standard setting
A systematic review of the association between anti-?-2 glycoprotein I antibodies and APS manifestations Jiang D, Lim W, Crowther M, Garcia D 2021 Blood Adv View Researchers Clinical research
Current and Future Perspectives for the Cryopreservation of Cord Blood Stem Cells Jahan S, Kaushal R, Pasha R, Pineault N 2021 Transfus Med Rev View Researchers New or improved product or process
Degradation of red blood cell deformability during cold storage in blood bags Islamzada E, Matthews K, Lamoureux ES, Duffy SP, Scott MD, Ma H 2021 eJHaem View Researchers Basic research
Blood unit segments accurately represent the biophysical properties of red blood cells in blood bags but not hemolysis Islamzada E, Matthews K, Lamoureux E, Duffy SP, Scott MD, Ma H 2022 Transfusion View Researchers Basic research
Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia Iba T, Levy JH, Warkentin TE 2022 Crit Care Med View Health care providers Benchmarking and standard setting
The authors reply Iba T, Levy JH, Warkentin TE 2022 Crit Care Med View Researchers Clinical research
Examining prescribing practices with respect to oral iron supplementation for post-partum anemia: a retrospective review Iancu AM, Buckstein J, Melamed N, Lin Y 2021 J Matern Fetal Neonatal Med View Health care providers Clinical research
Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia Huynh A, Kelton JG, Arnold DM, Daka M, Nazy I 2021 Nature View Researchers Clinical research
Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects Huynh A, Arnold DM, Smith JW, Moore JC, Zhang A, Chagla Z, Harvey BJ, Stacey HD, Ang JC, Clare R, Ivetic N, Chetty VT, Bowdish DME, Miller MS, Kelton JG, Nazy I 2021 Viruses View Researchers Clinical research
Exploring the reasons for low pertussis vaccine effectiveness in Ontario, Canada, 2006–2008: a Canadian Immunization Research Network study Hughes SL, Kwong JC, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Mahmud SM, Crowcroft NS 2022 Can J Public Health View Regulators Clinical research
Double high-dose immunoglobulin for ChAdOx1 nCov-19 vaccine-induced immune thrombotic thrombocytopenia Huang CT, Hsu SY, Wang CH, Tseng WJ, Yang CY, Ng CJ, Warkentin TE, Cheng MH 2021 Thromb Res View Researchers Clinical research
The Market in Noninvasive Prenatal Tests and the Message to Consumers: Exploring Responsibility Holloway K, Simms N, Hayeems RZ, Miller FA 2022 Hastings Cent Rep View Regulators Ethical, legal and social implications research
Blood bank storage of red blood cells increases RBC cytoplasmic membrane order and bending rigidity Himbert S, Qadri SM, Sheffield WP, Schubert P, D’Alessandro A, Rheinstädter MC 2021 PLoS One View Researchers Basic research
Teaching bone marrow procedures at pelvic and sternal sites: a high fidelity anatomy simulation Heather Vander M, Laureano M, Hu G, Lim W, Ross C, Wainman B, Zeller MP 2021 Can Med Educ J View Health care providers Benchmarking and standard setting
Sexual risk behavior questions: Understanding and mitigating donor discomfort Haw J, Woo H, Kohut T, Fisher W 2022 Transfusion View Blood operators MSM research
Blood Collection Agency Messaging to Donors and the Public in Canada and Australia During the Early Days of COVID-19 Haw J, Thorpe R, Holloway K 2022 Front Commun View Blood operators Ethical, legal and social implications research
Maintaining trust in a pandemic: Blood collection agency messaging to donors and the public during the early days of COVID-19 Haw J, Thorpe R, Holloway K 2021 SocArXiv View Blood operators Ethical, legal and social implications research