Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Neutropenia and monocytopenia in recurrent anaphylactoid reactions after red blood cell transfusions in a woman with immunoglobulin A (IgA) deficiency and anti-IgA Warkentin TE, Morin P-A, Heddle NM 2018 Transfusion View Health care providers Clinical research
SCAR: The high-prevalence antigen 013.008 in the Scianna blood group system Srivastava K, Albasri J, Alsuhaibani OM, Aljasem HA, Bueno MU, Antonacci T, Branch DR, Denomme GA, Flegel WA 2021 Transfusion View Researchers Basic research
An uncertain association between influenza season, recent influenza vaccination campaigns, and unconfirmed repeat reactive syphilis serology assay results in Canadian blood donors Drews SJ, Bodnar M, Gill B, Carson D, Hawes G, Yi QL, Tran V, Zhou HY, Bigham M, O'Brien SF 2022 Transfusion View Researchers Benchmarking and standard setting
Modeling unrelated blood stem cell donor recruitment using simulated registrant cohorts: Assessment of human leukocyte antigen matching across ethnicity groups Blake JT, Parmar G, Ganz K, Seftel MD, Allan DS 2023 Transfusion View Health care providers New or improved product or process
Automated closed volume reduction process for apheresis stem cell grafts: From development to clinical implementation Howell A, Letcher B, Murphy K, Elmoazzen H, Petraszko T, Acker JP, Pineault N, Holovati JL 2022 Transfusion View Researchers New or improved product or process
A data-informed system to manage scarce blood product allocation in a randomized controlled trial of convalescent plasma Li N, Zeller MP, Shih AW, Heddle NM, St. John M, Bégin P, Callum J, Arnold DM, Akbari-Moghaddam M, Down DG, Jamula E, Devine DV, Tinmouth A 2022 Transfusion View Researchers Clinical research
Evaluating the 4-hour and 30-minute rules: effects of room temperature exposure on red blood cell quality and bacterial growth Ramirez-Arcos S, Mastronardi C, Perkins H, Kou Y, Turner T, Mastronardi E, Hansen A, Yi QL, McLaughlin N, Kahwash E, Lin Y, Acker J 2013 Transfusion View Regulators New or improved product or process
Introduction of a closed-system cell processor for red blood cell washing: postimplementation monitoring of safety and efficacy Acker JP, Hansen AL, Yi Q-L, Sondi N, Cserti-Gazdewich C, Pendergrast J, Hannach B 2016 Transfusion View Blood operators New or improved product or process
Shining a light on AHG "blind" spot(s) Branch DR, Westhoff CM 2016 Transfusion View Researchers Basic research
The effects of rejuvenation during hypothermic storage on red blood cell membrane remodeling Kurach JDR, Almizraq R, Bicalho B, Acker JP, Holovati JL 2014 Transfusion View Researchers Basic research
Timing of gamma irradiation and blood donor sex influences in vitro characteristics of red blood cells de Korte D, Thibault L, Handke W, Harm SK, Morrison A, Fitzpatrick A, Marks DC, Yi QL, Acker JP 2018 Transfusion View Blood operators New or improved product or process
Warm-reactive (immunoglobulin G) autoantibodies and laboratory testing best practices: review of the literature and survey of current practice Ziman A, Cohn C, Carey PM, Dunbar NM, Fung MK, Greinacher A, Stanworth S, Heddle NM, Delaney M 2017 Transfusion View Health care providers New or improved product or process
Addressing the identity crisis in healthcare: positive patient identification technology reduces wrong patient events Callum J, Etchells E, Shojania K 2019 Transfusion View Health care providers Clinical research
Two-year follow-up of donors in a large national study of ferritin testing Goldman M, Uzicanin S, Osmond L, Yi Q-L, Scalia V, O'Brien SF 2018 Transfusion View Researchers Clinical research
A prospective observational study of the incidence, natural history, and risk factors for intravenous immunoglobulin-mediated hemolysis Pendergrast J, Armali C, Callum J, Cserti-Gazdewich C, Jiwajee A, Lieberman L, Lau W, Lin Y, Parmar N, Pavenski K, Riden LS, Shehata N, Willie-Ramharack K, Tomlinson G, Tong TN, Binnington B, Branch DR 2021 Transfusion View Researchers Clinical research
Staphylococcus epidermidis undergoes global changes in gene expression during biofilm maturation in platelet concentrates Loza-Correa M, Yousuf B, Ramirez-Arcos S 2021 Transfusion View Researchers Basic research
Noninvasive pH monitoring for bacterial detection in platelet concentrates Loza-Correa M, Perkins H, Kumaran D, Kou Y, Qaisar R, Geelhood S, Ramirez-Arcos S 2016 Transfusion View Researchers New or improved product or process
Quality of red blood cells washed using the ACP 215 cell processor: assessment of optimal pre- and postwash storage times and conditions Hansen A, Yi QL, Acker JP 2013 Transfusion View Researchers New or improved product or process
Research opportunities in optimizing storage of red blood cell products Wagner SJ, Glynn SA, Welniak LA, NHLBI Working Group on Strategies to Optimize Red Blood Cell Products 2014 Transfusion View Researchers Other
Transfusion premedication practices among pediatric health care practitioners in Canada: results of a national survey Solh Z, Chan AK, Heddle NM 2016 Transfusion View Health care providers Clinical research
Improved access to better HLA-matched hematopoietic cells for allogeneic transplant: analysis of donors and cord blood units selected for Canadian patients in 2018 Greco-Stewart V, Elmoazzen H, Morris G, Guo Y, Langdon C, Mercer D, Dibdin N, Allan DS 2020 Transfusion View Health care providers Clinical research
A naturally present autoantibody to senescent red blood cells? Badior KE, Bloch EM, Branch DR 2022 Transfusion View Researchers Benchmarking and standard setting
Reconsidering sickle cell trait testing of red blood cell units allocated to children with sickle cell disease Hajjaj OI, Cserti-Gazdewich C, Dumevska L, Hanna M, Lau W, Lieberman L 2023 Transfusion View Health care providers Clinical research
How do I provide rare red cells to patients? Laureano M, Clarke G, Yan MTS 2023 Transfusion View Health care providers Benchmarking and standard setting
A data-driven approach to determine daily platelet order quantities at hospitals Mirjalili M, Abouee-Mehrizi H, Barty R, Heddle NM, Sarhangian V 2022 Transfusion View Researchers New or improved product or process
2-HG inhibits necroptosis by stimulating DNMT1-dependent hypermethylation of the RIP3 promoter Yang Z, Jiang B, Wang Y, Ni H, Zhang J, Xia J, Shi M, Hung L, Ruan J, Mak T, Li Q, Han J 2017 Cell Rep View Researchers Basic research
A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory Yudin J, Heddle NM 2014 Lab Med View Health care providers Clinical research
Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP 2023 Sci Rep View Researchers Basic research
IVIG regulates the survival of human but not mouse neutrophils Schneider C, Wicki S, Graeter S, Timcheva TM, Keller CW, Quast I, Leontyev D, Djoumerska-Alexieva IK, Kasermann F, Jakob SM, Peyta D, Branch D, Cummings J, Kaufmann T, Simon H, Von Gunten S 2017 Sci Rep View Researchers Basic research
Selection and characterization of a DNA aptamer inhibiting coagulation factor XIa Donkor DA, Bhakta V, Eltringham-Smith LJ, Stafford AR, Weitz JI, Sheffield WP 2017 Sci Rep View Researchers Basic research
QSAR accelerated discovery of potent ice recrystallization inhibitors Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN 2016 Sci Rep View Researchers Basic research
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G 2022 Sci Rep View Researchers Clinical research
Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood Guo Q, Duffy SP, Matthews K, Islamzada E, Ma H 2017 Sci Rep View Researchers New or improved product or process
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN 2015 Sci Rep View Researchers New or improved product or process
Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing Briard JG, Poisson JS, Turner TR, Capicciotti CJ, Acker JP, Ben RN 2016 Sci Rep View Researchers New or improved product or process
CD8(+) T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia Qiu J, Liu X, Li X, Zhang X, Han P, Zhou H, Shao L, Hou Y, Min Y, Kong Z, Wang Y, Wei Y, Liu X, Ni H, Peng J, Hou M 2016 Sci Rep View Researchers Basic research
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP 2021 Sci Rep View Researchers Basic research
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H 2021 Sci Rep View Researchers Clinical research
Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses Marcoux G, Duchez A-C, Cloutier N, Provost P, Nigrovic PA, Boilard E 2016 Sci Rep View Researchers Basic research
Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP 2019 Sci Rep View Researchers Basic research
A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli Hun Yeon J, Chan KYT, Wong T-C, Chan K, Sutherland MR, Ismagilov RF, Pryzdial ELG, Kastrup CJ 2015 Sci Rep View Researchers Basic research
Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2 Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Foller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM 2015 Sci Rep View Researchers Basic research
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV 2014 Sci Rep View Researchers Basic research
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model Ren J, Ding X, Trudel M, Greer JJ, MacLean JE 2017 Sci Rep View Researchers Basic research
A bioinformatics approach to identify natural autoantibodies from healthy blood donors' sera reactive with the HCV NS5A-derived peptide by immunoassay Vasiljevic N, Veljkovic N, Kosec T, Ma XZ, Glisic S, Prljic J, Vujicic AD, Markovic L, Branch DR 2011 Viral Immunol View Researchers Basic research
Bacterial neuraminidase-mediated erythrocyte desialylation provokes cell surface aminophospholipid exposure Qadri SM, Donkor DA, Nazy I, Branch DR, Sheffield WP 2018 Eur J Haematol View Researchers Basic research
Impact of osteoblast maturation on their paracrine growth enhancing activity on cord blood progenitors Alsheikh M, Abu?Khader A, Michalicka M, Pasha R, Pineault N 2017 Eur J Haematol View Researchers Basic research
How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the Canadian PNH Network and review of the national registry Patriquin CJ, Kiss T, Caplan S, Chin-Yee I, Grewal K, Grossman J, Larratt L, Marceau D, Nevill T, Sutherland DR, Wells RA, Leber B 2019 Eur J Haematol View Researchers Clinical research
Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G, Sadikovic B 2016 Eur J Haematol View Researchers Clinical research
Utilization of a surgical database to provide care and assess perioperative treatment and outcomes in patients with bleeding disorders Olasupo OO, Haddix C, Nakar C, Maahs J, Greist A, Ghafoor A, Donfield SM, Iorio A, Shapiro AD 2022 Eur J Haematol View Health care providers Benchmarking and standard setting