Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
International survey of strategies to mitigate transfusion-transmitted Trypanosoma cruzi in non-endemic countries, 2016–2018 Crowder LA, Wendel S, Bloch EM, O'Brien SF, Delage G, Sauleda S, Leiby DA, for the WP-TTID Subgroup on Parasites 2022 Vox Sang View Researchers Benchmarking and standard setting
Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial Bégin P, Callum J, Heddle NM, Cook R, Zeller MP, Tinmouth A, Fergusson DA, Cushing MM, Glesby MJ, Chassé M, Devine DV, Robitalle N, Bazin R, Shehata N, Finzi A, McGeer A, Scales DC, Schwartz L, Turgeon AF, Zarychanski R, Daneman N, Carl R, Amorim L, Gabe C, Ellis M, Sachais BS, Loftsgard KC, Jamula E, Carruthers J, Duncan J, Lucier K, Li N, Liu Y, Armali C, Kron A, Modi D, Auclair M-C, Cerro S, Avram M, Arnold DM 2021 Trials View Researchers Clinical research
(NZW × BXSB) F1 male mice: An unusual, severe and fatal mouse model of lupus erythematosus Almizraq RJ, Frias Boligan K, Loriamini M, McKerlie C, Branch DR 2022 Front Immunol View Researchers Basic research
Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia Giles JB, Steiner HE, Rollin J, Shaffer CM, Momozawa Y, Mushiroda T, Inai C, Selleng K, Thiele T, Pouplard C, Heddle NM, Kubo M, Miller EC, Martinez KL, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM, Karnes JH 2022 Blood Adv View Researchers Basic research
Acid sphingomyelinase mediates murine acute lung injury following transfusion of aged platelets McVey MJ, Kim M, Tabuchi A, Srbely V, Japtok L, Arenz C, Rotstein O, Kleuser B, Semple JW, Kuebler WM 2017 Am J Physiol Lung Cell Mol Physiol View Researchers Basic research
Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior Burgess A, Dubey S, Yeung S, Hough O, Eterman N, Aubert I, Hynynen K 2014 Radiology View Researchers Basic research
Bioorthogonal phase-directed copper-catalyzed azide–alkyne cycloaddition (PDCuAAC) coupling of selectively cross-linked superoxide dismutase dimers produces a fully active bis-dimer Siren EM, Singh S, Kluger R 2015 Org Biomol Chem View Researchers Basic research
Cardiorespiratory pathogenesis of sickle cell disease in a mouse model Ren J, Ding X, Trudel M, Greer JJ, MacLean JE 2017 Sci Rep View Researchers Basic research
Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy Sun D, Shehata N, Ye XY, Gregorovich S, De France B, Arnold DM, Shah PS, Malinowski AK 2016 Blood View Researchers Clinical research
Determining the inventory impact of extended shelf life platelets with a network simulation model Blake J 2017 Transfusion View Researchers New or improved product or process
Encapsulation of factor IX-engineered mesenchymal stem cells in fibrinogen-alginate microcapsules enhances their viability and transgene secretion Sayyar B, Dodd M, Wen J, Ma S, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2012 J Tissue Eng View Researchers Basic research
Evidence for a novel mechanism independent of myocardial iron in beta-thalassemia cardiac pathogenesis Stoyanova E, Cloutier G, Felfly H, Lemsaddek W, Ah-Son N, Trudel M 2012 PLoS One View Researchers Basic research
Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 Artif Cells Nanomed Biotechnol View Researchers Basic research
Immunocamouflage: The biophysical basis of immunoprotection by grafted methoxypoly(ethylene glycol) (mPEG) Le Y, Scott MD 2010 Acta Biomater View Researchers Basic research
Increasing efficiency in protein-protein coupling: subunit-directed acetylation and phase-directed CuAAC ("click coupling") in the formation of hemoglobin bis-tetramers Wang A, Kluger R 2014 Biochemistry View Researchers Basic research
Mitochondrial damage-associated molecular patterns in blood transfusion products Marcoux G, Boilard E 2017 ISBT Sci Ser View Researchers Basic research
Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP) Zufferey A, Kapur R, Semple J 2017 J Clin Med View Researchers Basic research
Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA Duchez AC, Boudreau LH, Naika GS, Bollinger J, Belleannee C, Cloutier N, Laffont B, Mendoza-Villarroel RE, Levesque T, Rollet-Labelle E, Rousseau M, Allaeys I, Tremblay JJ, Poubelle PE, Lambeau G, Pouliot M, Provost P, Soulet D, Gelb MH, Boilard E 2015 PNAS View Researchers Basic research
Quality of red blood cells washed using an automated cell processor with and without irradiation Hansen AL, Turner TR, Yi QL, Acker JP 2014 Transfusion View Researchers New or improved product or process
Reply to: Short-Term versus Long-Term Blood Storage Heddle N 2017 N Engl J Med View Researchers Other
TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage Prudova A, Serrano K, Eckhard U, Fortelny N, Devine DV, Overall CM 2014 Blood View Researchers Basic research
The fibrinogen but not the Factor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice Eltringham-Smith LJ, Lei X, Reheman A, Lambourne MD, Pryzdial EL, Ni H, Sheffield WP 2014 Transfusion View Researchers Basic research
The size-dependent efficacy and biocompatibility of hyperbranched polyglycerol in peritoneal dialysis Du C, Mendelson AA, Guan Q, Chapanian R, Chafeeva I, da Roza G, Kizhakkedathu JN 2014 Biomaterials View Researchers Basic research
Using simulation to evaluate a blood supply network in the Canadian maritime provinces Blake J, Hardy M 2013 J Enterp Inf Manag View Researchers New or improved product or process
Concentré de recherche : Une façon nouvelle d'évaluer la qualité des globules rouges Acker J 2018 Blood.ca website View Researchers Clinical research
Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT Krauel K, Preuße P, Warkentin TE, Trabhardt C, Brandt S, Jensch I, Mandelkow M, Hammer E, Hammerschmidt S, Greinacher A 2018 Blood View Researchers Basic research
The sensitivity and specificity of platelet autoantibody testing in immune thrombocytopenia: a systematic review and meta-analysis of a diagnostic test Vrbensky JR, Moore JE, Arnold DM, Smith JW, Kelton JG, Nazy I 2019 J Thromb Haemost View Researchers Clinical research
Assessing the Vascular Deformability of Erythrocytes and Leukocytes: From Micropipettes to Microfluidics Scott M, Mathews K, Ma H 2019 Current and Future Aspects of Nanomedicine View Researchers Basic research
Deformability based sorting of stored red blood cells reveals donor-dependent aging curves Islamzada E, Matthews K, Guo Q, Santoso AT, Duffy SP, Scott MD, Ma H 2020 Lab Chip View Researchers Basic research
The impact of age and sex on first-time donor return behavior Masser BM, Wright S, Germain M, Grégoire Y, Goldman M, O'Brien SF, Kamel H, Bravo M, Merz EM, van den Hurk K, Prinsze F, Takanashi M, Wilder Z, Shaz B, Biomedical Excellence for Safer Transfusion (BEST) Collaborative 2020 Transfusion View Researchers Clinical research
A Canadian perspective on the use and preparation of cryopreserved red cell concentrates Turner TR, Acker JP 2020 Transfus Apher Sci View Researchers New or improved product or process
Control of data variations in intravital microscopy thrombosis models Lei X, MacKeigan DT, Ni H 2020 J Thromb Haemost View Researchers Basic research
Immune thrombocytopenia (ITP) World Impact Survey (I-WISh): Impact of ITP on health-related quality of life Cooper N, Kruse A, Kruse C, Watson S, Morgan M, Provan D, Ghanima W, Arnold DM, Tomiyama Y, Santoro C, Michel M, Laborde S, Lovrencic B, Hou M, Bailey T, Taylor-Stokes G, Haenig J, Bussel JB 2021 Am J Hematol View Researchers Clinical research
Editorial on Thaler et al. long-term follow-up after successful treatment of vaccine-induced prothrombotic immune thrombocytopenia. Thromb Res 2021 in press Warkentin TE, Pai M 2021 Thromb Res View Researchers Clinical research
Complete Genome Sequence of Staphylococcus aureus CI/BAC/25/13/W, Isolated from Contaminated Platelet Concentrates in England Paredes C, Chi SI, Flint A, Weedmark K, McDonald C, Bearne J, Ramirez-Arcos S, Pagotto F 2021 Microbiol Resour Announc View Researchers Benchmarking and standard setting
Response to ‘Adverse cardiac outcomes in patients with chronic myeloid leukaemia treated with tyrosine kinase inhibitors’ Leong D, Hillis C, Aghel N, Pond G, Seow H 2021 Heart View Researchers Clinical research
Transfusion of a platelet pool contaminated with exotoxin-producing Staphylococcus aureus: a case report Chi SI, Kumaran D, Zeller M, Ramirez-Arcos S 2021 Ann Blood View Researchers Clinical research
Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A Astermark J, Olsson A, Chelle P, Täckström K, Walger M, Magnusson M, Iorio A 2021 Haemophilia View Researchers Clinical research
Complement contributions to COVID-19 Conway EM, Pryzdial ELG 2022 Curr Opin Hematol View Researchers Basic research
Data for assessing red blood cell deformability from microscopy images using deep learning Lamoureux ES, Islamzada E, Wiens MVJ, Matthews K, Duffy SP, Ma H 2023 Data Brief View Researchers New or improved product or process
Evolving policies for donors with diabetes: The Canadian experience Miller O, Caffrey N, O'Brien SF, Goldman M 2022 Vox Sang View Researchers New or improved product or process
Assessing the quality of stored red blood cells using handheld Spatially Offset Raman spectroscopy with multisource correlation analysis Vardaki MZ, Georg Schulze H, Serrano K, Blades MW, Devine DV, F. B. Turner R 2022 Spectrochim Acta A Mol Biomol View Researchers New or improved product or process
An official American Thoracic Society/International Society for Heart and Lung Transplantation/Society of Critical Care Medicine/Association of Organ and Procurement Organizations/United Network of Organ Sharing Statement: ethical and policy considerations in organ donation after circulatory determination of death Gries CJ, White DB, Truog RD, Dubois J, Cosio CC, Dhanani S, Chan KM, Corris P, Dark J, Fulda G, Glazier AK, Higgins R, Love R, Mason DP, Nakagawa TA, Shapiro R, Shemie S, Tracy MF, Travaline JM, Valapour M, West L, Zaas D, Halpern SD, American Thoracic Society Health Policy Committee 2013 Am J Respir Crit Care Med View Researchers Benchmarking and standard setting
Attitudes toward Reciprocity Systems for Organ Donation and Allocation for Transplantation Burkell JA, Chandler JA, Shemie SD 2013 J Health Polit Policy Law View Researchers Other
Cellular immune dysfunction in immune thrombocytopenia (ITP) McKenzie CGJ, Guo L, Freedman J, Semple JW 2013 Br J Haematol View Researchers Basic research
CXCR4 transfection of cord blood mesenchymal stromal cells with the use of cationic liposome enhances their migration toward stromal cell-derived factor-1 Marquez-Curtis LA, Gul-Uludag H, Xu P, Chen J, Janowska-Wieczorek A 2013 Cytotherapy View Researchers Basic research
Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I 2015 Circ Res View Researchers Basic research
Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts Ratajczak MZ, Borkowska S, Mierzejewska K, Kucia M, Mendek-Czajkowska E, Suszynska M, Sharma VA, Deptala A, Song W, Platzbecker U, Larratt L, Janowska-Wieczorek A, Maciejewski J, Ratajczak J 2015 J Cell Mol Med View Researchers Basic research
Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-platelet therapy Zhu G, Zhang Q, Reddy EC, Carrim N, Chen Y, Xu XR, Xu M, Wang Y, Hou Y, Ma L, Li Y, Rui M, Petruzziello T, Lavalle C, Stratton TW, Lei X, Reheman A, Chen P, Zhu C, Wilkins JA, Hynes RO, Freedman J, Ni H 2017 Blood View Researchers Basic research
Leaving nothing to chance: how to randomize a clinical trial Toltl LJ, Arnold DM 2012 Transfusion View Researchers Other