Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
The potential utility of methoxypoly(ethylene glycol)-mediated prevention of rhesus blood group antigen RhD recognition in transfusion medicine Wang D, Toyofuku WM, Scott MD 2012 Biomaterials View Researchers Basic research
Two-year follow-up of donors in a large national study of ferritin testing Goldman M, Uzicanin S, Osmond L, Yi Q-L, Scalia V, O'Brien SF 2018 Transfusion View Researchers Clinical research
Protocol for a phase III, non-inferiority, randomised comparison of a new fibrinogen concentrate versus cryoprecipitate for treating acquired hypofibrinogenaemia in bleeding cardiac surgical patients: the FIBRES trial Karkouti K, Callum J, Rao V, Heddle N, Farkouh ME, Crowther MA, Scales DC 2018 BMJ Open View Researchers Clinical research
Patient Blood Management: Recommendations From the 2018 Frankfurt Consensus Conference Mueller MM, Van Remoortel H, Meybohm P, Aranko K, Aubron C, Burger R, Carson JL, Cichutek K, De Buck E, Devine D, Fergusson D, Folléa G, French C, Frey KP, Gammon R, Levy JH, Murphy MF, Ozier Y, Pavenski K, So-Osman C, Tiberghien P, Volmink J, Waters JH, Wood EM, Seifried E, ICC PBM Frankfurt Group 2019 JAMA View Researchers Clinical research
Concentré de recherche: Combattre l'inflammation par l'inflammation Lazarus A 2019 Blood.ca website View Researchers Clinical research
Comparative seasonalities of influenza A, B and 'common cold' coronaviruses - setting the scene for SARS-CoV-2 infections and possible unexpected host immune interactions Liu Y, Lam TTY, Lai FYL, Krajden M, Drews SJ, Hatchette TF, Fraaij PLA, van Kampen JJA, Badarch D, Nymadawa P, Tee KK, Lee HK, Koay ESC, Jennings L, Koopmans M, Tang JW 2020 J Infect View Researchers Clinical research
Direct comparison of two extended half-life PEGylated recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A Solms A, Shah A, Berntorp E, Tiede A, Iorio A, Linardi C, Ahsman M, Mancuso ME, Zhivkov T, Lissitchkov T 2020 Ann Hematol View Researchers Clinical research
A prospective observational study of the incidence, natural history, and risk factors for intravenous immunoglobulin-mediated hemolysis Pendergrast J, Armali C, Callum J, Cserti-Gazdewich C, Jiwajee A, Lieberman L, Lau W, Lin Y, Parmar N, Pavenski K, Riden LS, Shehata N, Willie-Ramharack K, Tomlinson G, Tong TN, Binnington B, Branch DR 2021 Transfusion View Researchers Clinical research
Tantalum-containing mesoporous bioactive glass powder for hemostasis Nagrath M, Gallant R, Yazdi AR, Mendonca A, Rahman S, Chiu L, Waldman SD, Ni H, Towler MR 2021 J Biomater Appl View Researchers Basic research
Genome Sequence of Staphylococcus aureus Strain PS/BAC/317/16/W, Isolated from Contaminated Platelet Concentrates in England Yousuf B, Flint A, Weedmark K, McDonald C, Bearne J, Pagotto F, Ramirez-Arcos S, Hotopp JCD 2021 Microbiol Resour Announc View Researchers Benchmarking and standard setting
Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2 Thiele T, Ulm L, Holtfreter S, Schönborn L, Kuhn SO, Scheer C, Warkentin TE, Bröker BM, Becker K, Aurich K, Selleng K, Hübner N-O, Greinacher A 2021 Blood View Researchers Clinical research
Heparin induced thrombocytopenia in relation to SARS-CoV-2 infection and ABO blood group Ray JG, Warkentin TE, Park AL 2021 Thromb Res View Researchers Clinical research
Staphylococcus epidermidis undergoes global changes in gene expression during biofilm maturation in platelet concentrates Loza-Correa M, Yousuf B, Ramirez-Arcos S 2021 Transfusion View Researchers Basic research
Current and Future Perspectives for the Cryopreservation of Cord Blood Stem Cells Jahan S, Kaushal R, Pasha R, Pineault N 2021 Transfus Med Rev View Researchers New or improved product or process
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19 Bégin P, Callum J, Cook R, Jamula E, Liu Y, Finzi A, Arnold DM 2022 Nat Med View Researchers Clinical research
The impact of biological age of red blood cell on in vitro endothelial activation markers Alshalani A, Beuger BM, Tuip-de Boer AM, van Bruggen R, Acker JP, Juffermans NP 2023 Front Physiol View Researchers Basic research
Removing the men who have sex with men blood donation deferral: Informing risk models using Canadian public health surveillance data Caffrey N, Goldman M, Lewin A, Grégoire Y, Yi QL, O’Brien SF 2022 Transfus Clin Biol View Researchers MSM research
SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada: a cross-sectional study Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Dhillon N, Irvine MA, Reicherz F, O’Reilly C, Sediqi S, Xu RY, Razzaghian HR, Sadarangani M, Coombs D, O’Brien SF, Lavoie PM 2022 BMJ Open View Researchers Clinical research
Doxorubicin-Induced Platelet Activation and Clearance Relieved by Salvianolic Acid Compound: Novel Mechanism and Potential Therapy for Chemotherapy-Associated Thrombosis and Thrombocytopenia Ma W, Rousseau Z, Slavkovic S, Shen C, Yousef GM, Ni H 2022 Pharmaceuticals View Researchers Basic research
Allogeneic platelet transfusions prevent murine T-cell–mediated immune thrombocytopenia Guo L, Yang L, Speck ER, Aslam R, Kim M, McKenzie CGJ, Lazarus AH, Ni H, Hou M, Freedman J, Semple JW 2014 Blood View Researchers Basic research
Antibody-mediated immune suppression is improved when blends of anti-RBC monoclonal antibodies are used in mice Bernardo L, Amash A, Marjoram D, Lazarus AH 2016 Blood View Researchers Basic research
Blood groups and susceptibility to virus infection: new developments Branch DR 2010 Curr Opin Hematol View Researchers Basic research
Concentré de recherche: Amélioration des résultats pour les patients présentant des troubles auto-immuns de la fonction plaquettaire Arnold D 2017 Blood.ca website View Researchers Basic research
Dengue virus replication by platelets Pryzdial ELG, Sutherland MR, Simon AY 2017 ISBT Sci Ser View Researchers Basic research
DJ-1/PARK7 Impairs Bacterial Clearance in Sepsis Amatullah H, Shan Y, Beauchamp BL, Gali PL, Gupta S, Maron-Gutierrez T, Speck ER, Fox-Robichaud AE, Tsang JLY, Mei SHJ, Mak TW, Rocco PRM, Semple JW, Zhang H, Hu P, Marshall JC, Stewart DJ, Harper M-E, Liaw PC, Liles WC, dos Santos CC, Canadian Critical Care Translational Biology Group (CCCTBG) 2017 Am J Respir Crit Care Med View Researchers Basic research
Effects of pathogen reduction systems on platelet microRNAs, mRNAs, activation, and function Osman A, Hitzler WE, Meyer CU, Landry P, Corduan A, Laffont B, Boilard E, Hellstern P, Vamvakas EC, Provost P 2015 Platelets View Researchers Basic research
FcgRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Nazi I, Arnold DM, Smith JW, Horsewood P, Moore JC, Warkentin TE, Crowther MA, Kelton JG 2013 J Thromb Haemost View Researchers Basic research
gT-S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo Sheffield WP, Lambourne MD, Eltringham-Smith LJ, Bhakta V, Arnold DM, Crowther MA 2014 J Thromb Haemost View Researchers Basic research
Identification of potential protein quality markers in pathogen inactivated and gamma-irradiated red cell concentrates Chen D, Schubert P, Devine DV 2017 Proteomics Clin Appl View Researchers Basic research
Microfluidic determination of lymphocyte vascular deformability: effects of intracellular complexity and early immune activation Kang N, Guo Q, Islamzada E, Ma H, Scott MD 2018 Integr Biol View Researchers Basic research
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice Chen J, Reheman A, Gushiken FC, Nolasco L, Fu X, Moake JL, Ni H, Lopez JA 2011 J Clin Invest View Researchers Basic research
Oxford's Systematic Review Initiative: leading by example in evidence-based transfusion medicine Fergusson DA 2016 Transfus Med View Researchers Clinical research
Polymer-mediated immunocamouflage of red blood cells: effects of polymer size on antigenic and immunogenic recognition of allogeneic donor blood cells Wang D, Kyluik DL, Murad KL, Toyofuku WM, Scott MD 2011 Sci China Life Sci View Researchers Basic research
Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate Lambourne MD, Eltringham-Smith LJ, Gataiance S, Arnold DM, Crowther MA, Sheffield WP 2012 J Thromb Haemost View Researchers Basic research
Quality of red blood cells washed using the ACP 215 cell processor: assessment of optimal pre- and postwash storage times and conditions Hansen A, Yi QL, Acker JP 2013 Transfusion View Researchers New or improved product or process
Research opportunities in optimizing storage of red blood cell products Wagner SJ, Glynn SA, Welniak LA, NHLBI Working Group on Strategies to Optimize Red Blood Cell Products 2014 Transfusion View Researchers Other
Splenic lymphocyte subtypes in immune thrombocytopenia: increased presence of a subtype of B-regulatory cells Aslam R, Segel GB, Burack R, Spence SA, Speck ER, Guo L, Semple JW 2016 Br J Haematol View Researchers Basic research
The Grand Challenges of Organ Banking: Proceedings from the first global summit on complex tissue cryopreservation Lewis JK, Bischof JC, Braslavsky I, Brockbank KGM, Fahy GM, Fuller BJ, Rabin Y, Tocchio A, Woods EJ, Wowk BG, Acker JP, Giwa S 2016 Cryobiology View Researchers Other
The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia Aslam R, Kapur R, Segel GB, Guo L, Zufferey A, Ni H, Semple JW 2016 Exp Hematol View Researchers Basic research
Genomic data in prognostic models-what is lost in translation? The case of deletion 17p and mutant TP53 in chronic lymphocytic leukaemia Chin-Yee B, Sadikovic B, Chin-Yee I 2019 Br J Haematol View Researchers Clinical research
Red blood cells, still vital after all these years: Commentary on Canadian Blood Services' International Symposium 2017 Qadri SM, Donkor DA, Yan M, Ning S, Branch DR, Seghatchian J, Sheffield WP 2018 Transfus Apher Sci View Researchers Other
Megakaryocyte apoptosis in immune thrombocytopenia Vrbensky JR, Nazy I, Toltl LJ, Ross C, Ivetic N, Smith JW, Kelton JG, Arnold DM 2018 Platelets View Researchers Basic research
The association between influenza vaccination and socioeconomic status in high income countries varies by the measure used: a systematic review Lucyk K, Simmonds KA, Lorenzetti DL, Drews SJ, Svenson LW, Russell ML 2019 BMC Med Red Methodol View Researchers Clinical research
Development and evaluation of a generic population pharmacokinetic model for standard half-life factor VIII for use in dose individualization McEneny-King A, Chelle P, Foster G, Keepanasseril A, Iorio A, Edginton AN 2019 J Pharmacokinet Pharmacodyn View Researchers Clinical research
The Impact of Bacterial Biofilms in Transfusion Medicine Ramirez-Arcos S 2020 Racing for the Surface View Researchers Basic research
Optimizing the supply of whole blood-derived bioproducts through the combined implementation of cryopreservation and pathogen reduction technologies and practices: An overview Bohonek M, Kutac D, Acker JP, Seghatchian J 2020 Transfus Apher Sci View Researchers New or improved product or process
Sex-mismatched red blood cell transfusions and mortality: A systematic review and meta-analysis Zeller MP, Rochwerg B, Jamula E, Li N, Hillis C, Acker JP, Runciman RJR, Lane SJ, Ahmed N, Arnold DM, Heddle NM 2019 Vox Sang View Researchers Clinical research
Cardiac donation after circulatory determination of death: protocol for a mixed-methods study of healthcare provider and public perceptions in Canada Honarmand K, Ball I, Weiss M, Slessarev M, Sibbald R, Sarti A, Meade M, D'Aragon F, Chasse M, Basmaji J, Parsons Leigh J 2020 BMJ Open View Researchers New or improved product or process
Control of ice recrystallization in liver tissues using small molecule carbohydrate derivatives William N, Acker JP 2020 Cryobiology View Researchers Basic research
Opportunities for standardization of cold stored, low-titre group O WB products Acker JP, Seghatchian J 2020 Transfus Apher Sci View Researchers New or improved product or process