Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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Mouse Models for Immune-Mediated Platelet Destruction or Immune Thrombocytopenia (ITP) | Neschadim A, Branch DR | 2016 | Curr Protoc Immunol | View Mouse Models for Immune-Mediated Platelet Destruction or Immune Thrombocytopenia (ITP) | Researchers | Basic research |
Osmotic parameters of red blood cells from umbilical cord blood | Zhurova M, McGann LE, Acker JP | 2014 | Cryobiology | View Osmotic parameters of red blood cells from umbilical cord blood | Researchers | Basic research |
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration | Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina MT, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan WI, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E | 2018 | PNAS | View Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration | Researchers | Basic research |
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations | Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN | 2015 | Sci Rep | View Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations | Researchers | New or improved product or process |
Synergistic effects of liposomes, trehalose, and hydroxyethyl starch for cryopreservation of human erythrocytes | Stoll C, Holovati JL, Acker JP, Wolkers WF | 2012 | Biotechnol Prog | View Synergistic effects of liposomes, trehalose, and hydroxyethyl starch for cryopreservation of human erythrocytes | Researchers | New or improved product or process |
Use of a Monocyte Monolayer Assay to Evaluate Fc gamma Receptor-mediated Phagocytosis | Tong T, Branch D | 2017 | J Vis Exp | View Use of a Monocyte Monolayer Assay to Evaluate Fc gamma Receptor-mediated Phagocytosis | Researchers | Basic research |
Vaccine Effectiveness Against Lineage-matched and -mismatched Influenza B Viruses Across 8 Seasons in Canada, 2010–2011 to 2017–2018 | Chambers C, Hickman R, Sabaiduc S, Chan T, Jassem A, Rose C, Krajden M, Skowronski DM, Petric M, De Serres G, Martineau C, Charest H, Winter A-L, Gubbay JB, Dickinson JA, Fonseca K, Drews SJ, Bastien N, Li Y | 2018 | Clin Infect Dis | View Vaccine Effectiveness Against Lineage-matched and -mismatched Influenza B Viruses Across 8 Seasons in Canada, 2010–2011 to 2017–2018 | Researchers | Clinical research |
An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing | Wong RW, Balachandran A, Cheung PK, Cheng R, Pan Q, Stoilov P, Harrigan PR, Blencowe BJ, Branch DR, Cochrane A | 2020 | PLoS Pathog | View An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing | Researchers | Basic research |
Critical developments of 2018: A review of the literature from selected topics in transfusion. A committee report from the AABB's Clinical Transfusion Medicine Committee | Cohn CS, Allen ES, Cushing MM, Dunbar NM, Friedman DF, Goel R, Harm SK, Heddle N, Hopkins CK, Klapper E, Perumbeti A, Ramsey G, Raval JS, Schwartz J, Shaz BH, Spinella PC, Pagano MB | 2019 | Transfusion | View Critical developments of 2018: A review of the literature from selected topics in transfusion. A committee report from the AABB's Clinical Transfusion Medicine Committee | Researchers | Clinical research |
HIV residual risk in Canada under a three-month deferral for men who have sex with men | O'Brien SF, Gregoire Y, Pillonel J, Steele WR, Custer B, Davison KL, Germain M, Lewin A, Seed CR | 2020 | Vox Sang | View HIV residual risk in Canada under a three-month deferral for men who have sex with men | Researchers | Other |
Modulating the T Lymphocyte Immune Response via Secretome Produced miRNA: From Tolerance Induction to the Enhancement of the Anticancer Response | Scott M, Wang D, Toyofuku W, Yang X | 2019 | Cells of the Immune System | View Modulating the T Lymphocyte Immune Response via Secretome Produced miRNA: From Tolerance Induction to the Enhancement of the Anticancer Response | Researchers | Basic research |
Using population-wide administrative and laboratory data to estimate type- and subtype-specific influenza vaccine effectiveness: a surveillance protocol | Scott AN, Buchan SA, Kwong JC, Drews SJ, Simmonds KA, Svenson LW | 2019 | BMJ Open | View Using population-wide administrative and laboratory data to estimate type- and subtype-specific influenza vaccine effectiveness: a surveillance protocol | Researchers | Clinical research |
A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies | Yao Z, Drecun L, Aboualizadeh F, Kim SJ, Li Z, Wood H, Valcourt EJ, Manguiat K, Plenderleith S, Yip L, Li X, Zhong Z, Yue FY, Closas T, Snider J, Tomic J, Drews SJ, Drebot MA, McGeer A, Ostrowski M, Mubareka S, Rini JM, Owen S, Stagljar I | 2021 | Nat Commun | View A homogeneous split-luciferase assay for rapid and sensitive detection of anti-SARS CoV-2 antibodies | Researchers | New or improved product or process |
Mucosal versus systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients | Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yun YF, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras A-C | 2020 | medRxiv | View Mucosal versus systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients | Researchers | Basic research |
Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation | Schubert P, Culibrk L, Culibrk B, Conway EM, Goodrich RP, Devine DV | 2021 | Transfusion | View Releasates of riboflavin/UV-treated platelets: Microvesicles suppress cytokine-mediated endothelial cell migration/proliferation | Researchers | Basic research |
Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time | Stonebraker JS, O'Mahony B, Noone D, Iorio A | 2021 | Haemophilia | View Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time | Researchers | Benchmarking and standard setting |
Evaluation of the sexual health in people living with hemophilia | Germini F, Chai-Adisaksopha C, Pete D, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker JS, Thabane L, Crowther MA, Skinner MW, Iorio A | 2021 | Haemophilia | View Evaluation of the sexual health in people living with hemophilia | Researchers | Clinical research |
A mixed methods investigation of the relationship between blood donor policy, interest in donation, and willingness to donate among gay, bisexual, and other men who have sex with men in Ontario, Canada | Armstrong JP, Brennan DJ, Collict D, Kesler M, Bekele T, Souleymanov R, Grace D, Lachowsky NJ, Hart TA, Adam BD | 2022 | BMC Public Health | View A mixed methods investigation of the relationship between blood donor policy, interest in donation, and willingness to donate among gay, bisexual, and other men who have sex with men in Ontario, Canada | Researchers | MSM research |
A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic | Grunau B, O’Brien SF, Kirkham TL, Helmer J, Demers PA, Asamoah-Boaheng M, Drews SJ, Karim ME, Srigley JA, Sediqi S, O’Neill D, Drennan IR, Goldfarb DM | 2022 | Ann Emerg Med | View A Prospective Observational Cohort Comparison of SARS-CoV-2 Seroprevalence Between Paramedics and Matched Blood Donors in Canada During the COVID-19 Pandemic | Researchers | Clinical research |
Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? | Kirkham AM, Bailey AJM, Shorr R, Lalu MM, Fergusson DA, Allan DS | 2023 | Cytotherapy | View Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? | Researchers | Clinical research |
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply | Mahamad S, Li N, Arnold DM | 2023 | J Thromb Haemost | View Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply | Researchers | Clinical research |
Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor | Gierczak RF, Pepler L, Bhagirath V, Liaw PC, Sheffield WP | 2014 | Thromb Res | View Alpha-1 proteinase inhibitor M358R reduces thrombin generation when displayed on the surface of cells expressing tissue factor | Researchers | Basic research |
Antimicrobial activity of flavonoids from Piper lanceaefolium and other Colombian medicinal plants against antibiotic susceptible and resistant strains of Neisseria gonorrhoeae | Ruddock PS, Charland M, Ramirez S, Lopez A, Neil Towers GH, Arnason JT, Liao M, Dillon JA | 2011 | Sex Transm Dis | View Antimicrobial activity of flavonoids from Piper lanceaefolium and other Colombian medicinal plants against antibiotic susceptible and resistant strains of Neisseria gonorrhoeae | Researchers | Basic research |
Cadherin 6 has a functional role in platelet aggregation and thrombus formation | Dunne E, Spring CM, Reheman A, Jin W, Berndt MC, Newman DK, Newman PJ, Ni H, Kenny D | 2012 | Arterioscler Thromb Vasc Biol | View Cadherin 6 has a functional role in platelet aggregation and thrombus formation | Researchers | Basic research |
Concentré de recherche: L'immunocamouflage au service des greffés et des transplantés | Scott M | 2017 | Blood.ca website | View Concentré de recherche: L'immunocamouflage au service des greffés et des transplantés | Researchers | Basic research |
Designing ice recrystallization inhibitors: from antifreeze (glyco)proteins to small molecules | Balcerzak AK, Capicciotti CJ, Briard JG, Ben RN | 2014 | RSC Adv | View Designing ice recrystallization inhibitors: from antifreeze (glyco)proteins to small molecules | Researchers | Basic research |
Does treatment order matter? Investigating the ability of bacteriophage to augment antibiotic activity against Staphylococcus aureus biofilms | Kumaran D, Taha M, Yi Q, Ramirez-Arcos S, Diallo JS, Carli A, Abdelbary H | 2018 | Front Microbiol | View Does treatment order matter? Investigating the ability of bacteriophage to augment antibiotic activity against Staphylococcus aureus biofilms | Researchers | Basic research |
Elevated Abundance, Size, and MicroRNA Content of Plasma Extracellular Vesicles in Viremic HIV-1+ Patients: Correlations With Known Markers of Disease Progression | Hubert A, Subra C, Jenabian MA, Tremblay Labrecque PF, Tremblay C, Laffont B, Provost P, Routy JP, Gilbert C | 2015 | J Acquir Immune Defic Syndr | View Elevated Abundance, Size, and MicroRNA Content of Plasma Extracellular Vesicles in Viremic HIV-1+ Patients: Correlations With Known Markers of Disease Progression | Researchers | Basic research |
Fetal and neonatal alloimmune thrombocytopenia | Zdravic D, Yougbare I, Vadasz B, Li C, Marshall AH, Chen P, Kjeldsen-Kragh J, Ni H | 2016 | Semin Fetal Neonatal Med | View Fetal and neonatal alloimmune thrombocytopenia | Researchers | Basic research |
Minimal dataset for post-registration surveillance of new drugs in hemophilia: communication from the SSC of the ISTH | Peyvandi F, Makris M, Collins P, Lillicrap D, Pipe SW, Iorio A, Rosendaal FR | 2017 | J Thromb Haemost | View Minimal dataset for post-registration surveillance of new drugs in hemophilia: communication from the SSC of the ISTH | Researchers | Clinical research |
Pathogen inactivation by riboflavin and ultraviolet light illumination accelerates the red blood cell storage lesion and promotes eryptosis | Qadri SM, Chen D, Schubert P, Perruzza DL, Bhakta V, Devine DV, Sheffield WP | 2017 | Transfusion | View Pathogen inactivation by riboflavin and ultraviolet light illumination accelerates the red blood cell storage lesion and promotes eryptosis | Researchers | Basic research |
Quality control of apheresis platelets: a multicentre study to evaluate factors that can influence pH measurement | Germain M, Grégoire Y, Vassallo RR, Acker JP, Cardigan R, de Korte D, Irving DO, Bégué S, on behalf of the BEST Collaborative | 2017 | Vox Sang | View Quality control of apheresis platelets: a multicentre study to evaluate factors that can influence pH measurement | Researchers | New or improved product or process |
Stability of Thawed Apheresis Fresh-Frozen Plasma Stored for up to 120 Hours at 1° C to 6° C | Sheffield WP, Bhakta V, Yi Q-L, Jenkins C | 2016 | J Blood Transfus | View Stability of Thawed Apheresis Fresh-Frozen Plasma Stored for up to 120 Hours at 1° C to 6° C | Researchers | Basic research |
Temperature stability of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] in the form of a solution or in the lyophilized form during storage at -80°C, 4°C, 25°C and 37°C or pasteurization at 70°C | Bian Y, Guo C, Chang T | 2016 | Artif Cells Nanomed Biotechnol | View Temperature stability of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] in the form of a solution or in the lyophilized form during storage at -80°C, 4°C, 25°C and 37°C or pasteurization at 70°C | Researchers | Basic research |
Closing in on DEHP-free red blood cell concentrate containers | Almizraq RJ, Acker J | 2018 | Transfusion | View Closing in on DEHP-free red blood cell concentrate containers | Researchers | New or improved product or process |
Risk-based decision making in transfusion medicine | Leach Bennett J, Devine DV | 2018 | Vox Sang | View Risk-based decision making in transfusion medicine | Researchers | New or improved product or process |
Human T-cell lymphotropic virus: A simulation model to estimate residual risk with universal leucoreduction and testing strategies in Canada | O'Brien SF, Yi Q-L, Goldman M, Grégoire Y, Delage G | 2018 | Vox Sang | View Human T-cell lymphotropic virus: A simulation model to estimate residual risk with universal leucoreduction and testing strategies in Canada | Researchers | New or improved product or process |
Healthcare provider knowledge, attitudes, beliefs, and practices surrounding the prescription of opioids for chronic non-cancer pain in North America: protocol for a mixed-method systematic review | Rash JA, Buckley N, Busse JW, Campbell TS, Corace K, Cooper L, Flusk D, Iorio A, Lavoie KL, Poulin PA, Skidmore B | 2018 | Systematic Reviews | View Healthcare provider knowledge, attitudes, beliefs, and practices surrounding the prescription of opioids for chronic non-cancer pain in North America: protocol for a mixed-method systematic review | Researchers | Clinical research |
Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets | Ni R, Neves MAD, Wu C, Cerroni SE, Flick MJ, Ni H, Weitz JI, Gross PL, Kim PY | 2020 | Thromb Haemost | View Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets | Researchers | Basic research |
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company | Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM | 2020 | Haemophilia | View Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company | Researchers | Clinical research |
Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study | Alabdullatif M, Osman IE, Alrasheed M, Ramirez-Arcos S, Alyousef M, Althawadi S, Alhumiadan H | 2021 | Transfusion | View Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood-derived platelets: A pilot study | Researchers | New or improved product or process |
Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP | Khan R, Menard M, Jen C-C, Chen X, Norris PAA, Lazarus AH | 2020 | Blood | View Inhibition of platelet phagocytosis as an in vitro predictor for therapeutic potential of RBC antibodies in murine ITP | Researchers | Basic research |
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients | Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC | 2020 | Sci Immunol | View Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients | Researchers | Clinical research |
A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors | Drews SJ, Devine DV, McManus J, Mendoza E, Manguiat K, Wood H, Girardin R, Dupuis A, McDonough K, Drebot M | 2021 | Transfusion | View A trend of dropping anti-SARS-CoV-2 plaque reduction neutralization test titers over time in Canadian convalescent plasma donors | Researchers | Basic research |
T cell-mediated autoimmunity in immune thrombocytopenia | Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM | 2022 | Eur J Haematol | View T cell-mediated autoimmunity in immune thrombocytopenia | Researchers | Clinical research |
Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference | Spinella PC, El Kassar N, Cap AP, Kindzelski AL, Almond CS, Barkun A, Gernsheimer TB, Goldstein JN, Holcomb JB, Iorio A, Jensen DM, Key NS, Levy JH, Mayer SA, Moore EE, Stanworth SJ, Lewis RJ, Steiner ME | 2021 | J Trauma Acute Care Surg | View Recommended primary outcomes for clinical trials evaluating hemostatic blood products and agents in patients with bleeding: Proceedings of a National Heart Lung and Blood Institute and US Department of Defense Consensus Conference | Researchers | Benchmarking and standard setting |
Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals | Bulmer T, Volders D, Blake J, Kamal N | 2021 | Front Neurol | View Discrete-Event Simulation to Model the Thrombolysis Process for Acute Ischemic Stroke Patients at Urban and Rural Hospitals | Researchers | New or improved product or process |
Impact of cardiopulmonary bypass duration on efficacy of fibrinogen replacement with cryoprecipitate compared with fibrinogen concentrate: a <em>post hoc</em> analysis of the Fibrinogen Replenishment in Surgery (FIBRES) randomised controlled trial | Bartoszko J, Martinez-Perez S, Callum J, Karkouti K, Farouh ME, Scales DC, Heddle NM, Crowther M, Rao V, Hucke H-P, Carroll J, Grewal D, Brar S, Brussières J, Grocott H, Harle C, Pavenski K, Rochon A, Saha T, Shepherd L, Syed S, Tran D, Wong D, Zeller M | 2022 | Br J Anaesth | View Impact of cardiopulmonary bypass duration on efficacy of fibrinogen replacement with cryoprecipitate compared with fibrinogen concentrate: a <em>post hoc</em> analysis of the Fibrinogen Replenishment in Surgery (FIBRES) randomised controlled trial | Researchers | Clinical research |
Evaluation of the performance of multiple immunoassay diagnostic platforms on the National Microbiology Laboratory SARS-CoV-2 National Serology Panel | Dibernardo A, Toledo NP, Robinson A, Osiowy C, Giles E, Day J, Lindsay LR, Drebot MA, Booth TF, Pidduck T, Baily A, Charlton CL, Tipples G, Kanji JN, Brochu G, Lang A, Therrien C, Bélanger-Collard M, Beaulac S-N, Gilfix BM, Boivin G, Hamelin M-È, Carbonneau J, Lévesque S, Martin P, Finzi A, Gendron-Lepage G, Goyette G, Benlarbi M, Gasser R, Fortin C, Martel-Lafferrière V, Lavoie M, Guérin R, Haraoui L-P, Renaud C, Jenkins C, O'Brien SF, Drews SJ, Conrod V, Tran V, Awrey B, Scheuermann R, DuPuis A, Payne A, Warszycki C, Girardin R, Lee W, Zahariadis G, Jiao L, Needle R, Cordenbach J, Zaharatos J, Taylor K, Teltscher M, Miller M, Elsherif M, Robertson P, Robinson JL | 2022 | J Assoc Med Microbiol Infect Dis Can | View Evaluation of the performance of multiple immunoassay diagnostic platforms on the National Microbiology Laboratory SARS-CoV-2 National Serology Panel | Researchers | Benchmarking and standard setting |
The bending rigidity of the red blood cell cytoplasmic membrane | Himbert S, D’Alessandro A, Qadri SM, Majcher MJ, Hoare T, Sheffield WP, Nagao M, Nagle JF, Rheinstädter MC | 2022 | PLoS One | View The bending rigidity of the red blood cell cytoplasmic membrane | Researchers | Basic research |