Our Research Publications
Updated November 2023
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Title | Authors | Year Sort ascending | Journal | Link to Article | Intended Audience | Purpose |
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Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? | Kirkham AM, Bailey AJM, Shorr R, Lalu MM, Fergusson DA, Allan DS | 2023 | Cytotherapy | View Systematic review and meta-analysis of randomized controlled trials of mesenchymal stromal cells to treat coronavirus disease 2019: is it too late? | Researchers | Clinical research |
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply | Mahamad S, Li N, Arnold DM | 2023 | J Thromb Haemost | View Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia: reply | Researchers | Clinical research |
White paper on pandemic preparedness in the blood supply | Strengers P, O'Brien SF, Politis C, Mayr W, Seifried E, Spencer BR | 2023 | Vox Sang | View White paper on pandemic preparedness in the blood supply | Blood operators | Benchmarking and standard setting |
Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study | Leong DP, Zhang A, Breznik JA, Clare R, Huynh A, Mushtaha M, Rangarajan S, Stacey H, Kim PY, Loeb M, Denburg JA, Mertz D, Chagla Z, Nazy I, Miller MS, Bowdish DME, Duong M | 2023 | PLoS One | View Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study | Researchers | Clinical research |
Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia | Gabe C, Liu Y, Duncan J, St John M, Lucier KJ, Kimmel D, Kelton JG, Arnold DM | 2023 | Platelets | View Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia | Researchers | Clinical research |
An expanded role for blood donor emerging pathogens surveillance | O’Brien SF, Goldman M, Drews S | 2023 | CMAJ | View An expanded role for blood donor emerging pathogens surveillance | Blood operators | New or improved product or process |
Proceedings of the immune thrombocytopenia summit: new concepts in mechanisms, diagnosis, and management | Mahamad S, Modi D, Al-Samkari H, Cuker A, Despotovic JM, Italiano JE, Lambert MP, Lee EJ, Rondina MT, Sholzberg M, Kruse C, Larché M, Nazy I, Miller MS, Arnold DM | 2023 | Res Pract Thromb Haemost | View Proceedings of the immune thrombocytopenia summit: new concepts in mechanisms, diagnosis, and management | Health care providers | Clinical research |
NAC Recommendations for the Use of Solvent-Detergent Plasma in Canada | Quinn JG, Pavenski K, Webert K, Ye S | 2023 | National Advisory Committee on Blood and Blood Products | View NAC Recommendations for the Use of Solvent-Detergent Plasma in Canada | Health care providers | Benchmarking and standard setting |
Adjudicating the Diagnosis of Immune Thrombocytopenia in a Clinical Research Study | Gabe C, Mahamad S, John M, Duncan J, Kelton J, Arnold D | 2023 | TH Open | View Adjudicating the Diagnosis of Immune Thrombocytopenia in a Clinical Research Study | Researchers | Clinical research |
Validation of a flow-cytometry-based red blood cell antigen phenotyping method | Liwski R, Clarke G, Cheng C, Abidi SSR, Abidi SR, Quinn JG | 2023 | Vox Sang | View Validation of a flow-cytometry-based red blood cell antigen phenotyping method | Health care providers | New or improved product or process |
Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | O’Brien SF, Reedman CN, Osiowy C, Bolotin S, Yi Q-L, Lourenço L, Lewin A, Binka M, Caffrey N, Drews SJ | 2023 | Viruses | View Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance | Researchers | Clinical research |
An online immunohematology educational resource for post-graduate hematology trainees: LearnSerology.ca | Arsenault V, Yan MTS, Tait G, Lewin A, Pendergrast J | 2023 | Transfus Apher Sci | View An online immunohematology educational resource for post-graduate hematology trainees: LearnSerology.ca | Health care providers | Education research |
Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency-first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository | Kumar R, Bakeer N, Dawson J, Al-Mughairy A, Stanek J, Dunn A, Male C, Chan A, Williams S | 2023 | J Thromb Haemost | View Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency-first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository | Researchers | Basic research |
How do I/we forecast tomorrows’ transfusion: Blood components | Pereyra N, Devine DV | 2023 | Transfus Clin Biol | View How do I/we forecast tomorrows’ transfusion: Blood components | Health care providers | New or improved product or process |
Use of selective phenotyping and genotyping to identify rare blood donors in Canada | Tordon B, Montemayor C, Clarke G, O'Brien SF, Goldman M | 2023 | Vox Sang | View Use of selective phenotyping and genotyping to identify rare blood donors in Canada | Blood operators | Clinical research |
Transfusion camp: A retrospective study of self-reported impact on postgraduate trainee transfusion practice | Yeung KCY, Kapitany C, Chargé S, Callum J, Cserti-Gazdewich C, D'Empaire PP, Khandelwal A, Lieberman L, Lee C, Pavenski K, Pendergrast J, Shehata N, Hsia CC, Lavoie M, Murphy MF, Prokopchuk-Gauk O, Rahmani M, Trudeau J, Zeller MP, Lin Y | 2023 | Transfusion | View Transfusion camp: A retrospective study of self-reported impact on postgraduate trainee transfusion practice | Health care providers | Education research |
Willingness and eligibility to donate blood under 12-month and 3-month deferral policies among gay, bisexual, and other men who have sex with men in Ontario, Canada | Brennan D, Armstrong JP, Kesler M, Bekele T, Lachowksy N, Grace D, Hart TA, Souleymanov R, Adam B | 2023 | PLOS Glob Public Health | View Willingness and eligibility to donate blood under 12-month and 3-month deferral policies among gay, bisexual, and other men who have sex with men in Ontario, Canada | Researchers | MSM research |
BAY 81-8973 Efficacy and Safety in Previously Untreated and Minimally Treated Children with Severe Hemophilia A: The LEOPOLD Kids Trial | Ljung R, Chan AKC, Glosli H, Afonja O, Becker B, Tseneklidou-Stoeter D, Mancuso ME, Saulyte-Trakymiene S, Kenet G | 2023 | Thromb Haemost | View BAY 81-8973 Efficacy and Safety in Previously Untreated and Minimally Treated Children with Severe Hemophilia A: The LEOPOLD Kids Trial | Researchers | Clinical research |
Determining the Optimal SARS-CoV-2 mRNA Vaccine Dosing Interval for Maximum Immunogenicity | Asamoah-Boaheng M, Goldfarb D, Prusinkiewicz MA, Golding L, Karim ME, Barakauskas V, Wall N, Jassem AN, Marquez AC, MacDonald C, O'Brien SF, Lavoie P, Grunau B | 2023 | Cureus | View Determining the Optimal SARS-CoV-2 mRNA Vaccine Dosing Interval for Maximum Immunogenicity | Researchers | Clinical research |
Staphylococcal Enterotoxins Enhance Biofilm Formation by Staphylococcus aureus in Platelet Concentrates | Chi SI, Ramirez-Arcos S | 2023 | Microorganisms | View Staphylococcal Enterotoxins Enhance Biofilm Formation by Staphylococcus aureus in Platelet Concentrates | Researchers | Basic research |
‘A Most Equitable Drug’: How the Clinical Studies of Convalescent Plasma as a Treatment for SARS-CoV-2 Might Usefully Inform Post-Pandemic Public Sector Approaches to Drug Development | Grundy Q, Campbell C, Ali R, Herder M, Holloway K | 2023 | J Law Med Ethics | View ‘A Most Equitable Drug’: How the Clinical Studies of Convalescent Plasma as a Treatment for SARS-CoV-2 Might Usefully Inform Post-Pandemic Public Sector Approaches to Drug Development | Researchers | Ethical, legal & social implications research |
Massive Hemorrhage Protocol: A Practical Approach to the Bleeding Trauma Patient | Petrosoniak A, Pavenski K, da Luz LT, Callum J | 2023 | Emerg Med Clin North Am | View Massive Hemorrhage Protocol: A Practical Approach to the Bleeding Trauma Patient | Health care providers | Benchmarking and standard setting |
Severe fetal anemia caused by anti-Jra: Burst forming unit-erythroid colony formation inhibition assay suggesting possible erythroid suppression mechanism | Tran A, Yan MTS, Branch DR, Blacquiere M, Pineault N, Pasha R, Clarke G | 2023 | Transfusion | View Severe fetal anemia caused by anti-Jra: Burst forming unit-erythroid colony formation inhibition assay suggesting possible erythroid suppression mechanism | Researchers | Clinical research |
Clinical Outcomes of Umbilical Cord Blood Transplantation Using Ex Vivo Expansion: A Systematic Review and Meta-Analysis of Controlled Studies | Saiyin T, Kirkham AM, Bailey AJM, Shorr R, Pineault N, Maganti HB, Allan DS | 2023 | Transplant Cell Ther | View Clinical Outcomes of Umbilical Cord Blood Transplantation Using Ex Vivo Expansion: A Systematic Review and Meta-Analysis of Controlled Studies | Researchers | Clinical research |
The Missing Pieces to the Cold-Stored Platelet Puzzle | Zhao H, Devine DV | 2022 | Int J Mol Sci | View The Missing Pieces to the Cold-Stored Platelet Puzzle | Researchers | Basic research |
Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies | Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS | 2022 | Cytotherapy | View Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies | Researchers | Clinical research |
The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update | Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup | 2022 | Vox Sang | View The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update | Researchers | Benchmarking and standard setting |
Vaccine-induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources | Greinacher A, Langer F, Makris M, Pai M, Pavord S, Tran H, Warkentin TE | 2022 | J Thromb Haemost | View Vaccine-induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources | Health care providers | Clinical research |
Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination | Breznik JA, Huynh A, Zhang A, Bilaver L, Bhakta H, Stacey HD, Ang JC, Bramson JL, Nazy I, Miller MS, Denburg J, Costa AP, Bowdish DME | 2022 | J Immunol | View Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination | Health care providers | Clinical research |
THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets | Gil Gonzalez L, Fernandez-Marrero Y, Norris PAA, Tawhidi Z, Shan Y, Cruz-Leal Y, Won KD, Frias-Boligan K, Branch DR, Lazarus AH | 2022 | PLoS One | View THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets | Researchers | Basic research |
ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM | 2022 | Blood | View ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Researchers | Basic research |
Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation | Olafson C, William N, Howell A, Beaudin L, Gill B, Clarke G, Stephens S, Lopes-Carvalho D, Lane D, Schubert P, McTaggart K, Acker JP | 2022 | Transfusion | View Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation | Researchers | New or improved product or process |
Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood | Stewart T | 2022 | Blood.ca website | View Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood | Health care providers | Benchmarking and standard setting |
Circulaire d'information utilisation de composants sanguins humains: Plaquettes | Stewart T | 2022 | Blood.ca website | View Circulaire d'information utilisation de composants sanguins humains: Plaquettes | Health care providers | Benchmarking and standard setting |
Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies | Gajic-Veljanoski O, Li C, Schaink AK, Guo J, Shehata N, Charames GS, de Vrijer B, Clarke G, Pechlivanoglou P, Okun N, Kandel R, Dooley J, Higgins C, Ng V, Sikich N | 2022 | Transfusion | View Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies | Researchers | Clinical research |
HIV residual risk in Canada for apheresis source plasma donation without deferral for men who have sex with men | Aubé E, Lewin A, O'Brien SF, Grégoire Y, Pillonel J, Steele WR, Custer B, Davison KL, Germain M, Seed CR, Camirand Lemyre F, the Surveillance RA, Policy Subgroup of the ISBT Transfusion Transmitted Infectious Diseases Working Party | 2022 | Vox Sang | View HIV residual risk in Canada for apheresis source plasma donation without deferral for men who have sex with men | Blood operators | MSM research |
The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults | Asamoah-Boaheng M, Goldfarb DM, Karim ME, O’Brien SF, Wall N, Drews SJ, Barakauskas V, Jassem AN, Grunau B | 2022 | J Infect Dis | View The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults | Researchers | Clinical research |
HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada | Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA | 2022 | Transfusion | View HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada | Researchers | MSM research |
Chapter 5. Concentrates for hemostatic disorders and hereditary angioedema | Poon MC, Goodyear D, Rydz N, Lee A | 2022 | Clinical Guide to Transfusion | View Chapter 5. Concentrates for hemostatic disorders and hereditary angioedema | Health care providers | Benchmarking and standard setting |
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study | Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative | 2022 | Transfusion | View Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study | Researchers | Benchmarking and standard setting |
Impacts of COVID-19 and elective surgery cancellations on platelet supply and utilization in the Canadian Province of British Columbia | Shopsowitz KE, Lim C, Shih AW, Fishbane N, Berry BR, Bigham M, Petraszko T, Trudeau J, Wyatt M, Yan MTS, Morrison D | 2022 | Vox Sang | View Impacts of COVID-19 and elective surgery cancellations on platelet supply and utilization in the Canadian Province of British Columbia | Blood operators | Benchmarking and standard setting |
SARS-CoV-2 Virus-Like Particle Neutralizing Capacity in Blood Donors Depends on Serological Profile and Donor-Declared SARS-CoV-2 Vaccination History | Drews SJ, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Mostafa HH | 2022 | Microbiol Spectr | View SARS-CoV-2 Virus-Like Particle Neutralizing Capacity in Blood Donors Depends on Serological Profile and Donor-Declared SARS-CoV-2 Vaccination History | Researchers | Clinical research |
Chapitre 19. Plaquettes à teneur réduite en agents pathogènes | Blais-Normandin I, Tordon B, Anani W, Ning S | 2022 | Guide de la pratique transfusionnelle | View Chapitre 19. Plaquettes à teneur réduite en agents pathogènes | Health care providers | Benchmarking and standard setting |
National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies | Holmberg JA, Henry SM, Burnouf T, Devine D, Marschner S, Boothby TC, Burger SR, Chou ST, Custer B, Blumberg N, Siegel DL, Spitalnik SL | 2022 | Transfusion | View National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies | Researchers | Benchmarking and standard setting |
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia | Li N, Mahamad S, Parpia S, Iorio A, Foroutan F, Heddle NM, Hsia CC, Sholzberg M, Rimmer E, Shivakumar S, Sun HL, Refaei M, Hamm C, Arnold DM | 2022 | J Thromb Haemost | View Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia | Researchers | New or improved product or process |
Surveillance report | O'Brien SF | 2022 | Blood.ca website | View Surveillance report | Blood operators | Benchmarking and standard setting |
Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex | Sask KN, Thong B, Goodarzynejad N, Berry LR, Chan AKC | 2022 | Biointerphases | View Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex | Researchers | Basic research |
GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach | Zeng L, Brignardello-Petersen R, Hultcrantz M, Mustafa RA, Murad MH, Iorio A, Traversy G, Akl EA, Mayer M, Schünemann HJ, Guyatt GH | 2022 | J Clin Epidemiol | View GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach | Researchers | Clinical research |
Massive Hemorrhage Protocol: Quality Metrics Portal Pilot | Thompson T, Callum J | 2022 | Ontario Regional Blood Coordinating Network February 2022 Newsletter | View Massive Hemorrhage Protocol: Quality Metrics Portal Pilot | Health care providers | Clinical research |
Survey of blood centre readiness regarding removal of DEHP from blood bag sets: The BEST Collaborative Study | Razatos A, Acker JP, de Korte D, Bégué S, Noorman F, Doyle B, Zia M, Min K, The Biomedical Excellence for Safer Transfusion Collaborative | 2022 | Vox Sang | View Survey of blood centre readiness regarding removal of DEHP from blood bag sets: The BEST Collaborative Study | Researchers | New or improved product or process |