Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
The effect of grafted methoxypoly(ethylene glycol) chain length on the inhibition of respiratory syncytial virus (RSV) infection and proliferation Sutton TC, Scott MD 2010 Biomaterials View Researchers Basic research
The nonhemostatic immune functions of platelets Kapur R, Semple JW 2016 Semin Hematol View Researchers Basic research
Translational feasibility of soluble nanobiotherapeutics with enhanced red blood cell functions Chang TMS 2017 Artif Cells Nanomed Biotechnol View Researchers New or improved product or process
Vox Sanguinis International Forum on donor notification and counselling strategies for markers of transfusion-transmissible infections Sharma RR, Lozano M, Fearon M, Bigham M, Djoudi R, Gallian P, Woimant G, Lee C, Leung JNS, Tsoi WC, Marwaha N, Sachdev S, Tadokoro K, Tani Y, Matsukura H, Gbuz So O, Shantseva N, Zhiburt E, Hindawi S, Chay J, Huang T, Teo D, Moleli N, Oyonarte S, Jayasekara SBA, Bokhorst A, van den Burg P, Hewitt P, Bianco C, Kessler D 2017 Vox Sang View Researchers Clinical research
Concentré de recherche: Rôle du groupe sanguin dans le déclenchement d'une hémolyse après l'administration d'immunoglobulines Branch D 2018 Blood.ca website View Researchers Basic research
Pathogen inactivation strategies to improve blood safety: Let's not throw pathogen-reduced platelets out with their bath water Devine DV 2018 JAMA Oncol View Researchers New or improved product or process
Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin MacIsaac J, Siddiqui R, Jamula E, Li N, Baker S, Webert KE, Evanovitch D, Heddle NM, Arnold DM 2018 Transfusion View Researchers Clinical research
GPIb? is required for platelet-mediated hepatic thrombopoietin generation Xu M, Li J, Neves MAD, Zhu G, Carrim N, Yu R, Gupta S, Marshall J, Rotstein O, Peng J, Hou M, Kunishima S, Ware J, Branch DR, Lazarus A, Ruggeri ZM, Freedman J, Ni H 2018 Blood View Researchers Basic research
Prevalence of Babesia in Canadian blood donors: June–October 2018 Tonnetti L, O'Brien SF, Grégoire Y, Proctor MC, Drews SJ, Delage G, Fearon MA, Brès V, Linnen JM, Stramer SL 2019 Transfusion View Researchers Clinical research
Antiviral anticoagulation Pryzdial ELG, Sutherland MR, Lin BH, Horwitz M 2020 Res Pract Thromb Haemost View Researchers Basic research
FcgammaRI and FcgammaRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia Norris PAA, Segel GB, Burack WR, Sachs UJ, Lissenberg-Thunnissen SN, Vidarsson G, Bayat B, Cserti-Gazdewich CM, Callum J, Lin Y, Branch D, Kapur R, Semple JW, Lazarus AH 2021 Haematologica View Researchers Basic research
Pragmatic, double-blind, randomised trial evaluating the impact of red blood cell donor sex on recipient mortality in an academic hospital population: the innovative Trial Assessing Donor Sex (iTADS) protocol Fergusson DA, Chassé M, Tinmouth A, Acker JP, English S, Forster AJ, Hawken S, Shehata N, Thavorn K, Wilson K, Tuttle A, Perelman I, Cober N, Maddison H, Tokessy M 2021 BMJ Open View Researchers Clinical research
A simple protein-based surrogate neutralization assay for SARS-CoV-2 Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis Ii AP, Girardin RC, Rathod B, Wang J, Barrios-Rodiles M, Colwill K, McGeer A, Mubareka S, Gommerman JL, Durocher Y, Ostrowski M, McDonough KA, Drebot MA, Drews SJ, Rini JM, Gingras AC 2020 JCI Insight View Researchers New or improved product or process
DNA Mediated Blood Coagulation: Extracellular DNA Accelerates Fibrinogen Polymerization By Thrombin Independent of Contact Pathway Vappala S, Straus S, Pryzdial EL, Conway E, Kizhakkedathu J 2021 Blood View Researchers Basic research
Reconstituted cryopreserved platelets synthesize proteins during short-term storage and packaging a defined subset into microvesicles Schubert P, Johnson L, Culibrk B, Chen Z, Tan S, Marks DC, Devine DV 2021 Transfusion View Researchers New or improved product or process
Dimethyl sulfoxide-free cryopreservation solutions for hematopoietic stem cell grafts Kaushal R, Jahan S, McGregor C, Pineault N 2022 Cytotherapy View Researchers New or improved product or process
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O'Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G 2022 Sci Rep View Researchers Clinical research
Thymic stromal lymphopoietin induces platelet mitophagy and promotes thrombosis in Kawasaki disease Fu L, MacKeigan DT, Gong Q, Che D, Xu Y, Pi L, Sun C, Yu H, Chen K, Zhou H, Jiang Z, Wang Z, Zhang L, Cerenzia EG, Ni H, Gu X 2023 Brit J Haem View Researchers Clinical research
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O’Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
A flow cytometric method for platelet counting in platelet concentrates van der Meer PF, Karssing-van Leeuwen W, Kurtz J, Spengler H-P, Blair A, Devine D, Harrison P, Lambrecht B, VandenBroeke T, de Wildt J, de Korte D, on behalf of the Biomedical Excellence for Safer Transfusion C 2012 Transfusion View Researchers New or improved product or process
A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K 2016 Trials View Researchers Clinical research
Alpha-1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis McCurdy TR, Patrick AL, Eltringham-Smith LJ, Bhakta V, Sheffield WP, Fox-Robichaud AE 2014 Microcirculation View Researchers Basic research
Antigens protected functional red blood cells by the membrane grafting of compact hyperbranched polyglycerols Chapanian R, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu J 2013 J Vis Exp View Researchers Basic research
Buffy coat (top/bottom)- and whole-blood filtration (top/top)-produced red cell concentrates differ in size of extracellular vesicles Bicalho B, Pereira AS, Acker JP 2015 Vox Sang View Researchers Basic research
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N 2013 Nat Med View Researchers Basic research
Concentré de recherche: La sécrétion de cellules immunitaires peut protéger les patients contre le syndrome respiratoire post-transfusionnel Semple J 2017 Blood.ca website View Researchers Basic research
Design, implementation, and evaluation of a knowledge translation intervention to increase organ donation after cardiocirculatory death in Canada: a study protocol Squires JE, Grimshaw JM, Taljaard M, Linklater S, Chasse M, Shemie SD, Knoll GA 2014 Implement Sci View Researchers Other
Efficiency of riboflavin and ultraviolet light treatment against high levels of biofilm?derived Staphylococcus epidermidis in buffy coat platelet concentrates Taha M, Culibrk B, Kalab M, Schubert P, Yi QL, Goodrich R, Ramirez?Arcos S 2017 Vox Sang View Researchers New or improved product or process
Evaluation of CONSORT compliance in TRANSFUSION Jaffer AM, Wang G, Barty RL, Shih AW 2015 Transfusion View Researchers Other
Hematopoietic Stem Cell Mobilization and Homing after Transplantation: The Role of MMP-2, MMP-9, and MT1-MMP Shirvaikar N, Marquez-Curtis LA, Janowska-Wieczorek A 2012 Biochem Res Int View Researchers Basic research
IgG-Mediated Immune Suppression to Erythrocytes by Polyclonal Antibodies Can Occur in the Absence of Activating or Inhibitory Fc? Receptors in a Full Mouse Model Bernardo L, Yu H, Amash A, Zimring JC, Lazarus AH 2015 J Immunol View Researchers Basic research
In silico analysis suggests repurposing of ibuprofen for prevention and treatment of EBOLA virus disease Veljkovic V, Goeijenbier M, Glisic S, Veljkovic N, Perovic VR, Sencanski M, Branch DR, Paessler S 2015 F1000Res View Researchers Basic research
Involvement of the contact phase and intrinsic pathway in herpes simplex virus-initiated plasma coagulation Gershom ES, Sutherland MR, Lollar P, Pryzdial EL 2010 J Thromb Haemost View Researchers Basic research
Maestro tissue factor reaches new hEIGHT Pryzdial ELG 2017 Blood View Researchers Basic research
Migration, proliferation and differentiation of cord blood mesenchymal stromal cells treated with histone deacetylase inhibitor valproic acid Marquez-Curtis LA, Qiu Y, Xu A, Janowska-Wieczorek A 2014 Stem Cells Int View Researchers Basic research
Platelet concentrate functionality assessed by thromboelastography or rotational thromboelastometry Arbaeen AF, Serrano K, Levin E, Devine DV 2016 Transfusion View Researchers Basic research
rIgG1 Fc hexamer inhibits antibody-mediated autoimmune disease via effects on complement and FcgammaRs Spirig R, Campbell IK, Koernig S, Chen CG, Lewis BJB, Butcher R, Muir I, Taylor S, Chia J, Leong D, Simmonds J, Scotney P, Schmidt P, Fabri L, Hofmann A, Jordi M, Spycher MO, Cattepoel S, Brasseit J, Panousis C, Rowe T, Branch DR, Baz Morelli A, Kasermann F, Zuercher AW 2018 J Immunol View Researchers Basic research
Sialylation-independent mechanism involved in the amelioration of murine immune thrombocytopenia using intravenous gammaglobulin Leontyev D, Katsman Y, Ma XZ, Miescher S, Kasermann F, Branch DR 2012 Transfusion View Researchers Basic research
Towards a prophylactic treatment of HPA-related foetal and neonatal alloimmune thrombocytopenia Kjeldsen-Kragh J, Ni H, Skogen B 2012 Curr Opin Hematol View Researchers Other
Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A 2019 Haemophilia View Researchers Clinical research
Cellular immune responses to platelet factor 4 and heparin complexes in patients with heparin-induced thrombocytopenia Nazy I, Clare R, Staibano P, Warkentin TE, Larché M, Moore JC, Smith JW, Whitlock RP, Kelton JG, Arnold DM 2018 J Thromb Haemost View Researchers Clinical research
Modulating Intracellular Ice Growth with Cell-Permeating Small-Molecule Ice Recrystallization Inhibitors Poisson JS, Acker JP, Briard JG, Meyer JE, Ben RN 2018 Langmuir View Researchers Basic research
The Monocyte Monolayer Assay: Past, Present and Future Tong TN, Cen S, Branch DR 2018 Transfus Med Rev View Researchers Basic research
Corrigendum to "Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity" [J. Biotechnol. 208 (2015) 54-62] Gierczak RF, Bhakta V, Xie M, Sheffield WP 2020 J Biotechnol View Researchers Basic research
Modulating Intracellular Ice Growth with Cell-Permeating Small-Molecule Ice Recrystallization Inhibitors Poisson JS, Acker JP, Briard JG, Meyer JE, Ben RN 2019 Langmuir View Researchers Basic research
Using pharmacokinetics for tailoring prophylaxis in people with hemophilia switching between clotting factor products: A scoping review Yu JK, Iorio A, Edginton AN, Wapps co?investigators 2019 Res Pract Thromb Haemost View Researchers Clinical research
The Effect of Age and Type of Media on Growth Kinetics of Human Amniotic Fluid Stem cells Borzou B, Mehrabani D, Zare S, Zamani-Pereshkaft M, Acker JP 2020 Biopreserv Biobank View Researchers Basic research
HIT: still stringing us along Warkentin TE 2020 Blood View Researchers Clinical research
Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells Bissinger R, Petkova-Kirova P, Mykhailova O, Oldenborg P-A, Novikova E, Donkor DA, Dietz T, Bhuyan AAM, Sheffield WP, Grau M, Artunc F, Kaestner L, Acker JP, Qadri SM 2020 Cell Signal View Researchers Basic research