Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N 2013 Nat Med View Researchers Basic research
Crosstalk between Platelets and the Immune System: Old Systems with New Discoveries Li C, Li J, Li Y, Lang S, Yougbare I, Zhu G, Chen P, Ni H 2012 Adv Hematol View Researchers Basic research
Development of a high-yield expression and purification system for platelet factor 4 Huynh A, Arnold DM, Moore JC, Smith JW, Kelton JG, Nazy I 2017 Platelets View Researchers Basic research
Heterogeneity in Studies of Mesenchymal Stromal Cells to Treat or Prevent Graft-versus-Host Disease: A Scoping Review of the Evidence Rizk M, Monaghan M, Shorr R, Kekre N, Bredeson CN, Allan DS 2016 Biol Blood Marrow Transplant View Researchers Basic research
Inhibition of allogeneic cytotoxic T cell (CD8+) proliferation via polymer-induced Treg (CD4+) cells Kang N, Toyofuku WM, Yang X, Scott MD 2017 Acta Biomat View Researchers Basic research
Mechanism of hemoglobin-induced cellular injury in desiccated red blood cells Kanias T, Acker JP 2010 Free Radic Biol Med View Researchers Basic research
Modulation of microRNA Activity by Semi-microRNAs Plante I, Ple H, Landry P, Gunaratne PH, Provost P 2012 Front Genet View Researchers Basic research
Novel insight into stem cell mobilization-Plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex Ratajczak MZ, Lee H, Wysoczynski M, Wan W, Marlicz W, Laughlin MJ, Kucia M, Janowska-Wieczorek A, Ratajczak J 2010 Leukemia View Researchers Basic research
PEGylation prevents bacteria-induced platelet activation and biofilm formation in platelet concentrates Greco CA, Maurer-Spurej E, Scott MD, Kalab M, Nakane N, Rami­rez-Arcos SM 2011 Vox Sang View Researchers Basic research
Platelet transfusion reactions do not occur more often in recipients transfused with apheresis versus buffy coat platelet concentrates Cserti-Gazdewich C, Escorcia A, Pendergrast J, Lieberman L, Skeate R, Lin Y, Callum J 2016 Transfusion View Researchers Clinical research
Prevention of surface-induced thrombogenesis on poly(vinyl chloride) Fedorov K, Jankowski A, Sheikh S, Blaszykowski C, Reheman A, Romaschin A, Ni H, Thompson M 2015 J Mater Chem B Mater Biol Med View Researchers Basic research
Raman spectroscopy of stored red blood cells: evaluating clinically-relevant biochemical markers in donated blood Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB 2015 Clin Biomed Spectrosc Imag IV View Researchers New or improved product or process
Targeting transfusion-related acute lung injury: the journey from basic science to novel therapies Semple JW, McVey MJ, Kim M, Rebetz J, Kuebler WM, Kapur R 2018 Crit Care Med View Researchers Basic research
Biofilm-associated accumulation-associated protein (Aap): A contributing factor to the predominant growth of Staphylococcus epidermidis in platelet concentrates Alabdullatif M, Ramirez-Arcos S 2019 Vox Sang View Researchers New or improved product or process
Compliance with time-based deferrals for men who have sex with men O'Brien SF, Osmond L, Fan W, Yi Q-L, Goldman M 2019 Transfusion View Researchers MSM research
Bacterial safety of blood components - a congress review of the ISBT transfusion-transmitted infectious diseases working party, bacterial subgroup Ramirez-Arcos S, McDonald C, Deol P, Kreuger AL, Patel N, Pidcoke H, Prax M, Seltsam A, Stassinopoulos A, The ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria 2019 ISBT Sci Ser View Researchers Other
Natural, not immune; classical, not alternative Warkentin TE 2018 Blood View Researchers Other
Increased cytotoxic potential of CD8(+) T cells in immune thrombocytopenia Vrbensky JR, Arnold DM, Kelton JG, Smith JW, Jaffer AM, Larché M, Clare R, Ivetic N, Nazy I 2020 Br J Haematol View Researchers Basic research
Pharmacy hydroxyurea education materials for patients with sickle cell disease: An environmental scan and assessment of accuracy Cervi A, Diamantouros A, Azzam M, Lane SJ, Sapru H, Verhovsek M 2020 Pediatr Blood Cancer View Researchers Benchmarking and standard setting
Inhibition of in vitro Ebola infection by anti-parasitic quinoline derivatives Goyal S, Binnington B, McCarthy SDS, Desmaële D, Férrié L, Figadère B, Loiseau PM, Branch DR 2020 F1000Research View Researchers Basic research
Persistence of CRISPR/Cas9 gene edited hematopoietic stem cells following transplantation: A systematic review and meta-analysis of preclinical studies Maganti HB, Bailey AJM, Kirkham AM, Shorr R, Pineault N, Allan DS 2021 Stem Cells Transl Med View Researchers Basic research
Translating bioactive peptides for COVID-19 therapy Bhullar KS, Drews SJ, Wu J 2021 Eur J Pharmacol View Researchers Basic research
Inductively-Coupled Plasma Mass Spectrometry-Novel Insights From an Old Technology Into Stressed Red Blood Cell Physiology Stephenson D, Nemkov T, Qadri SM, Sheffield WP, D'Alessandro A 2022 Front Physiol View Researchers Basic research
COVID-19 Case Age Distribution: Correction for Differential Testing by Age Fisman DN, Greer A, Brankston G, Hillmer M, O'Brien SF, Drews S, Tuite AR 2021 Ann Intern Med View Researchers Clinical research
Ketamine administration for acute painful sickle cell crisis: A randomized controlled trial Alshahrani MS, AlSulaibikh AH, ElTahan MR, AlFaraj SZ, Asonto LP, AlMulhim AA, AlAbbad MF, Almaghraby N, AlJumaan MA, AlJunaid TO, Darweesh MN, AlHawaj FM, Mahmoud AM, Alossaimi BK, Alotaibi SK, AlMutairi TM, AlSulaiman Pharm DD, Alfaraj D, Alhawwas R, Mbuagbaw L, Lewis K, Verhovsek M, Crowther M, Guyatt G, Alhazzani W 2021 Acad Emerg Med View Researchers Clinical research
The Cost Effectiveness of Axicabtagene Ciloleucel Versus Best Supportive Care in the Treatment of Adult Patients with Relapsed or Refractory Large B-Cell Lymphoma (LBCL) After Two or More Lines of Systemic Therapy in Canada Hillis C, Vicente C, Ball G 2022 Pharmacoeconomics View Researchers Clinical research
The evaluation of constant coronary artery flow versus constant coronary perfusion pressure during normothermic ex situ heart perfusion Qi X, Hatami S, Bozso S, Buchko M, Forgie KA, Olafson C, Khan M, Himmat S, Wang X, Nobes DS, Acker JP, Nagendran J, Freed DH 2022 J Heart Lung Transplant View Researchers Basic research
Activated platelets can deliver mRNA regulatory Ago2-microRNA complexes to endothelial cells via microparticles Laffont B, Corduan A, Plé H, Duchez AC, Cloutier N, Boilard E, Provost P 2013 Blood View Researchers Basic research
Assessing the Rationale and Effectiveness of Frozen Plasma Transfusions: An Evidence-based Review Tinmouth A 2016 Hematol Oncol Clin North Am View Researchers Clinical research
CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fc? Receptor– and Complement Receptor 3–Dependent Mechanisms Amash A, Wang L, Wang Y, Bhakta V, Fairn GD, Hou M, Peng J, Sheffield WP, Lazarus AH 2016 J Immunol View Researchers Basic research
Deformability based cell sorting using microfluidic ratchets enabling phenotypic separation of leukocytes directly from whole blood Guo Q, Duffy SP, Matthews K, Islamzada E, Ma H 2017 Sci Rep View Researchers New or improved product or process
Difficulties in establishing the diagnosis of immune thrombocytopenia: An agreement study Salib M, Clayden R, Clare R, Wang G, Warkentin TE, Crowther MA, Lim W, Nazi I, Kelton JG, Arnold DM 2016 Am J Hematol View Researchers Clinical research
Genome-wide association study of erythrocyte density in sickle cell disease patients Ilboudo Y, Bartolucci P, Rivera A, Sedzro JC, Beaudoin M, Trudel M, Alper SL, Brugnara C, Galacteros F, Lettre G 2017 Blood Cells Mol Dis View Researchers Basic research
Human Endothelial Colony-Forming Cells Protect against Acute Kidney Injury: Role of Exosomes Burger D, Viñas JL, Akbari S, Dehak H, Knoll W, Gutsol A, Carter A, Touyz RM, Allan DS, Burns KD 2015 Am J Pathol View Researchers Basic research
Microfluidic analysis of cellular deformability of normal and oxidatively-damaged red blood cells Kwan JM, Quan Guo Q, Kyluik-Price DL, Ma H, Scott MD 2013 Am J Hematol View Researchers Basic research
Mouse Models for Immune-Mediated Platelet Destruction or Immune Thrombocytopenia (ITP) Neschadim A, Branch DR 2016 Curr Protoc Immunol View Researchers Basic research
Osmotic parameters of red blood cells from umbilical cord blood Zhurova M, McGann LE, Acker JP 2014 Cryobiology View Researchers Basic research
Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration Cloutier N, Allaeys I, Marcoux G, Machlus KR, Mailhot B, Zufferey A, Levesque T, Becker Y, Tessandier N, Melki I, Zhi H, Poirier G, Rondina MT, Italiano JE, Flamand L, McKenzie SE, Cote F, Nieswandt B, Khan WI, Flick MJ, Newman PJ, Lacroix S, Fortin PR, Boilard E 2018 PNAS View Researchers Basic research
Suicidal death of erythrocytes in cancer and its chemotherapy: A potential target in the treatment of tumor-associated anemia Lang E, Bissinger R, Qadri SM, Lang F 2017 Int J Cancer View Researchers Basic research
The effect of liposome treatment on the quality of hypothermically stored red blood cells Stadnick H, Stoll C, Wolkers WF, Acker JP, Holovati JL 2011 Biopreserv Biobank View Researchers New or improved product or process
Thromboelastometry reveals similar hemostatic properties of purified fibrinogen and a mixture of purified cryoprecipitate protein components Qadri SM, Eltringham-Smith LJ, Bhakta V, Sheffield WP 2018 Clin Chem Lab Med View Researchers Basic research
Drug-induced immune haemolytic anaemias Branch DR 2019 ISBT Sci Ser View Researchers Basic research
Erratum to: The Perioperative Anticoagulant Use for Surgery Evaluation (PAUSE) Study for Patients on a Direct Oral Anticoagulant who Need an Elective Surgery or Procedure: Design and Rationale Douketis JD SA, Anderson JM, Arnold DM, Bates SM, Blostein M, Carrier M, Caprini JA, Clark NP, Coppens M, Dentali F, Duncan J, Gross PL, Kassis J, Kowalski S, Lee AY, Gal GL, Templier GL, Li N, MacKay E, Shah V, Shivakumar S, Solymoss S, Spencer FA, Syed S, Tafur AJ, Vanassche T, Thiele T, Wu C, Yeo E, Schulman S. 2018 Thromb Haemost View Researchers Clinical research
Quality of evidence-based guidelines for transfusion of red blood cells and plasma: A systematic review Pavenski K, Stanworth S, Fung M, Wood EM, Pink J, Murphy MF, Hume H, Nahirniak S, Webert KE, Tanael S, Landry D, Shehata N 2018 Transfus Med Rev View Researchers Clinical research
Apolipoprotein A-IV binds alpha II beta 3 integrin and inhibits thrombosis Xu XR, Wang Y, Adili R, Ju L, Spring CM, Jin JW, Yang H, Neves MAD, Chen P, Yang Y, Lei X, Chen Y, Gallant RC, Xu M, Zhang H, Song J, Ke P, Zhang D, Carrim N, Yu S-Y, Zhu G, She Y-M, Cyr T, Fu W, Liu G, Connelly PW, Rand ML, Adeli K, Freedman J, Lee JE, Tso P, Marchese P, Davidson WS, Jackson SP, Zhu C, Ruggeri ZM, Ni H 2018 Nat Commun View Researchers Basic research
Coagulation factor VIIa binds to herpes simplex virus 1-encoded glycoprotein C forming a factor X-enhanced tenase complex oriented on membranes Lin BH, Sutherland MR, Rosell FI, Morrissey JH, Pryzdial ELG 2020 J Thromb Haemost View Researchers Basic research
Label-Free Analysis of Red Blood Cell Storage Lesions Using Imaging Flow Cytometry Pinto RN, Sebastian JA, Parsons MJ, Chang TC, Turner TR, Acker JP, Kolios MC 2019 Cytom Part A View Researchers New or improved product or process
Prevalence of Red Blood Cell Major Blood Group Antigens and Phenotypes among Omani Blood Donors Al-Riyami AZ, Al-Marhoobi A, Al-Hosni S, Al Mahrooqi S, Schmidt M, O'Brien SF, Al-Khabori M 2019 Oman Med J View Researchers Clinical research
Stabilization of Lipid Membranes through Partitioning of the Blood Bag Plasticizer Di-2-ethylhexyl phthalate (DEHP) Bider R-C, Lluka T, Himbert S, Khondker A, Qadri SM, Sheffield WP, Rheinstädter MC 2020 Langmuir View Researchers Basic research
Cold-stored leukoreduced whole blood: Extending the time between donation and filtration has minimal impact on in vitro quality Schubert P, Chen Z, Bhakta V, Culibrk B, Wambolt R, Sheffield WP, Devine DV, McTaggart K 2021 Transfusion View Researchers New or improved product or process