Our Research Publications
Updated November 2023
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Title | Authors | Year Sort descending | Journal | Link to Article | Intended Audience | Purpose |
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(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium | Jimenez-Diaz MB, Ebert D, Salinas Y, Pradhan A, Lehane AM, Myrand-Lapierre ME, O'Loughlin KG, Shackleford DM, Justino de Almeida M, Carrillo AK, Clark JA, Dennis AS, Diep J, Deng X, Duffy S, Endsley AN, Fedewa G, Guiguemde WA, Gomez MG, Holbrook G, Horst J, Kim CC, Liu J, Lee MC, Matheny A, Martinez MS, Miller G, Rodriguez-Alejandre A, Sanz L, Sigal M, Spillman NJ, Stein PD, Wang Z, Zhu F, Waterson D, Knapp S, Shelat A, Avery VM, Fidock DA, Gamo FJ, Charman SA, Mirsalis JC, Ma H, Ferrer S, Kirk K, Angulo-Barturen I, Kyle DE, DeRisi JL, Floyd DM, Guy RK | 2014 | PNAS | View (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium | Researchers | Basic research |
A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models | Sheffield WP, Eltringham-Smith LJ, Gataiance S, Bhakta V | 2014 | J Thromb Thrombolysis | View A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models | Researchers | Basic research |
Cytokine profiles in mouse models of experimental immune thrombocytopenia reveal a lack of inflammation and differences in response to intravenous immunoglobulin depending on the mouse strain | Leontyev D, Neschadim A, Branch DR | 2014 | Transfusion | View Cytokine profiles in mouse models of experimental immune thrombocytopenia reveal a lack of inflammation and differences in response to intravenous immunoglobulin depending on the mouse strain | Researchers | Basic research |
Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis | Chasse M, English S, McIntyre L, Knoll G, Shehata N, Forster A, Wilson K, van Walraven C, Tinmouth A, Fergusson D | 2014 | Syst Rev | View Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis | Researchers | Clinical research |
How to get a paper published | Walsh GM, Devine DV | 2014 | ISBT Sci Ser | View How to get a paper published | Other | Other |
Optimal Attenuation of Experimental Autoimmune Encephalomyelitis by Intravenous Immunoglobulin Requires an Intact Interleukin-11 Receptor | Figueiredo CA, Drohomyrecky PC, McCarthy SDS, Leontyev D, Ma X-Z, Branch DR, Dunn SE | 2014 | PLoS One | View Optimal Attenuation of Experimental Autoimmune Encephalomyelitis by Intravenous Immunoglobulin Requires an Intact Interleukin-11 Receptor | Researchers | Basic research |
Segments from red blood cell units should not be used for quality testing | Kurach JDR, Hansen AL, Turner TR, Jenkins C, Acker JP | 2014 | Transfusion | View Segments from red blood cell units should not be used for quality testing | Blood operators | New or improved product or process |
Structure-activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias | Purohit MK, Chakka SK, Scovell I, Neschadim A, Bello AM, Salum N, Katsman Y, Bareau MC, Branch DR, Kotra LP | 2014 | Bioorg Med Chem | View Structure-activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias | Researchers | Basic research |
Understanding why patients with immune thrombocytopenia are deeply divided on splenectomy | Wang KK, Charles C, Heddle NM, Arnold E, Molnar L, Arnold DM | 2014 | Health Expect | View Understanding why patients with immune thrombocytopenia are deeply divided on splenectomy | Health care providers | Clinical research |
Antibody-Mediated Immune Suppression of Erythrocyte Alloimmunization Can Occur Independently from Red Cell Clearance or Epitope Masking in a Murine Model | Yu H, Stowell SR, Bernardo L, Hendrickson JE, Zimring JC, Amash A, Uchikawa M, Lazarus AH | 2014 | J Immunol | View Antibody-Mediated Immune Suppression of Erythrocyte Alloimmunization Can Occur Independently from Red Cell Clearance or Epitope Masking in a Murine Model | Researchers | Basic research |
Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol | Lalu MM, Moher D, Marshall J, Fergusson D, Mei SH, Macleod M, Griffin G, Turgeon AF, Rudnicki M, Fishman J, Avey MT, Skidmore B, Grimshaw JM, Stewart DJ, Singh K, McIntyre L | 2014 | Syst Rev | View Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol | Researchers | Clinical research |
Plasma fibronectin supports hemostasis and regulates thrombosis | Wang Y, Reheman A, Spring CM, Kalantari J, Marshall AH, Wolberg AS, Gross PL, Weitz JI, Rand ML, Mosher DF, Freedman J, Ni H | 2014 | J Clin Invest | View Plasma fibronectin supports hemostasis and regulates thrombosis | Researchers | Basic research |
Short daily versus conventional hemodialysis for hypertensive patients: a randomized cross-over study | Zimmerman DL, Ruzicka M, Hebert P, Fergusson D, Touyz RM, Burns KD | 2014 | PLoS One | View Short daily versus conventional hemodialysis for hypertensive patients: a randomized cross-over study | Health care providers | Clinical research |
Are donors in Canada compliant with deferral for tattoos and piercing? | O'Brien S F, Xi G, Fan W, Yi Q, Osmond L, Delage G, Goldman M | 2014 | Blood Transfus | View Are donors in Canada compliant with deferral for tattoos and piercing? | Blood operators | New or improved product or process |
Engineering biomaterials surfaces to modulate the host response | Yu K, Mei Y, Hadjesfandiari N, Kizhakkedathu JN | 2014 | Colloids Surf B Biointerfaces | View Engineering biomaterials surfaces to modulate the host response | Researchers | Basic research |
First analysis of 10-year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System | Traore AN, Chan AKC, Webert KE, Heddle N, Ritchie B, St-Louis J, Teitel J, Lillicrap D, Iorio A, Walker I | 2014 | Haemophilia | View First analysis of 10-year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System | Health care providers | Clinical research |
Mixed field reactions in ABO and Rh typing chimerism likely resulting from twin haematopoiesis | Sharpe C, Lane D, Cote J, Hosseini-Maaf B, Goldman M, Olsson ML, Hult AK | 2014 | Blood Transfus | View Mixed field reactions in ABO and Rh typing chimerism likely resulting from twin haematopoiesis | Health care providers | Clinical research |
Transfusion-related lung injury in children: a case series and review of the literature | Lieberman L, Petraszko T, Yi QL, Hannach B, Skeate R | 2014 | Transfusion | View Transfusion-related lung injury in children: a case series and review of the literature | Health care providers | Clinical research |
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis | Lei X, Reheman A, Hou Y, Zhou H, Wang Y, Marshall AH, Liang C, Dai X, Li BX, Vanhoorelbeke K, Ni H | 2014 | Thromb Haemost | View Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis | Researchers | Basic research |
Comparative efficacy of blood cell immunocamouflage by membrane grafting of methoxypoly(ethylene glycol) and polyethyloxazoline | Kyluik-Price DL, Li L, Scott MD | 2014 | Biomaterials | View Comparative efficacy of blood cell immunocamouflage by membrane grafting of methoxypoly(ethylene glycol) and polyethyloxazoline | Researchers | Basic research |
How to succeed in research during medical training: a qualitative study | Alak A, Jerzak KJ, Quirt JA, Lane SJ, Miller PA, Haider S, Arnold DM | 2014 | Clin Invest Med | View How to succeed in research during medical training: a qualitative study | Health care providers | Clinical research |
Internal medicine resident knowledge of transfusion medicine: results from the BEST-TEST international education needs assessment | Haspel RL, Lin Y, Mallick R, Tinmouth A, Cid J, Eichler H, Lozano M, van de Watering L, Fisher PB, Ali A, Parks E | 2014 | Transfusion | View Internal medicine resident knowledge of transfusion medicine: results from the BEST-TEST international education needs assessment | Health care providers | Other |
ResearchUnit: Dodging disinfection: biofilm-forming skin bacteria can resist disinfectants | Ramirez-Arcos S | 2014 | Blood.ca website | View ResearchUnit: Dodging disinfection: biofilm-forming skin bacteria can resist disinfectants | Other | Other |
The efficacy and safety of plasma exchange in patients with sepsis and septic shock: a systematic review and meta-analysis | Rimmer E, Houston BL, Kumar A, Abou-Setta AM, Friesen C, Marshall JC, Rock G, Turgeon AF, Cook DJ, Houston DS, Zarychanski R | 2014 | Crit Care | View The efficacy and safety of plasma exchange in patients with sepsis and septic shock: a systematic review and meta-analysis | Health care providers | Clinical research |
The procoagulant envelope virus surface: contribution to enhanced infection | Pryzdial EL, Sutherland MR, Ruf W | 2014 | Thromb Res | View The procoagulant envelope virus surface: contribution to enhanced infection | Researchers | Basic research |
What should men living with haemophilia need to know? The perspectives of Canadian men with haemophilia | Arnold E, Lane S, Webert KE, Chan A, Walker I, Tufts J, Rubin S, Poon MC, Heddle NM | 2014 | Haemophilia | View What should men living with haemophilia need to know? The perspectives of Canadian men with haemophilia | Health care providers | Other |
In reply to 'dialysis vintage could confound survival trends in ESRD patients' | van Walraven C, Manuel D, Knoll G | 2014 | Am J Kidney Dis | View In reply to 'dialysis vintage could confound survival trends in ESRD patients' | Health care providers | Other |
p38MAPK is involved in apoptosis development in apheresis platelet concentrates after riboflavin and ultraviolet light treatment | Chen Z, Schubert P, Culibrk B, Devine DV | 2014 | Transfusion | View p38MAPK is involved in apoptosis development in apheresis platelet concentrates after riboflavin and ultraviolet light treatment | Researchers | Basic research |
Postdonation Information and Blood Component Retrievals: Realigning Blood Center and Hospital Actions Based on Risk Assessment | Eder AF, Goldman M | 2014 | Transfus Med Rev | View Postdonation Information and Blood Component Retrievals: Realigning Blood Center and Hospital Actions Based on Risk Assessment | Blood operators | Other |
Sustained expression of coagulation Factor IX by modified cord blood-derived mesenchymal stromal cells | Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G | 2014 | J Gene Med | View Sustained expression of coagulation Factor IX by modified cord blood-derived mesenchymal stromal cells | Researchers | Basic research |
Acquired peanut hypersensitivity following platelet transfusion | Ponnampalam A, Growe G, Loftus P, Chipperfield K, Bigham M | 2014 | Transfus Med | View Acquired peanut hypersensitivity following platelet transfusion | Health care providers | Clinical research |
Counting platelets at transfusion threshold levels: impact on the decision to transfuse. A BEST Collaborative - UK NEQAS(H) International Exercise | Lozano M, Mahon A, van der Meer PF, Stanworth S, Cid J, Devine D, Fung MK, de la Salle B, Heddle NM, on behalf of Biomedical Excellence for Safer Transfusion Collaborative | 2014 | Vox Sang | View Counting platelets at transfusion threshold levels: impact on the decision to transfuse. A BEST Collaborative - UK NEQAS(H) International Exercise | Health care providers | Benchmarking and standard setting |
Targeting activated platelets and fibrinolysis: hitting two birds with one stone | Reheman A, Xu X, Reddy EC, Ni H | 2014 | Circ Res | View Targeting activated platelets and fibrinolysis: hitting two birds with one stone | Researchers | Basic research |
Vitamin D and kidney transplant outcomes: a protocol for a systematic review and meta-analysis | Hesketh CC, Knoll GA, Molnar AO, Tsampalieros A, Zimmerman DL | 2014 | Syst Rev | View Vitamin D and kidney transplant outcomes: a protocol for a systematic review and meta-analysis | Researchers | Clinical research |
Different doses of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation (Protocol) | Estcourt LJ, Stanworth S, Doree C, Trivella M, Hopewell S, Murphy MF, Tinmouth A | 2014 | Cochrane Database Syst Rev | View Different doses of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation (Protocol) | Researchers | Clinical research |
A thermoreversible poly(choline phosphate) based universal biomembrane adhesive | Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE | 2014 | Macromol Biosci | View A thermoreversible poly(choline phosphate) based universal biomembrane adhesive | Researchers | Basic research |
Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence | Kayibanda JF, Hiremath S, Knoll GA, Fergusson D, Chow BJ, Shabana W, Akbari A | 2014 | Syst Rev | View Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence | Researchers | Clinical research |
Evaluation of a universal point-of-issue assay for bacterial detection in buffy coat platelet components | Ramirez-Arcos S, Kou Y, Perkins H | 2014 | Vox Sang | View Evaluation of a universal point-of-issue assay for bacterial detection in buffy coat platelet components | Blood operators | New or improved product or process |
Feasibility and transport of packed red blood cells into Special Forces operational conditions | Boscarino C, Tien H, Acker J, Callum J, Hansen AL, Engels P, Glassberg E, Nathens A, Beckett A | 2014 | J Trauma Acute Care Surg | View Feasibility and transport of packed red blood cells into Special Forces operational conditions | Other | New or improved product or process |
Reference intervals of complete blood count constituents are highly correlated to waist circumference: Should obese patients have their own “normal values?†| Vuong J, Qiu Y, La M, Clarke G, Swinkels DW, Cembrowski G | 2014 | Am J Hematol | View Reference intervals of complete blood count constituents are highly correlated to waist circumference: Should obese patients have their own “normal values?†| Health care providers | Clinical research |
The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis | Kosan C, Rashkovan M, Ross J, Schaffer AM, Saba I, Lemsaddek W, Trudel M, Moroy T | 2014 | Am J Blood Res | View The transcription factor Miz-1 is required for embryonic and stress-induced erythropoiesis but dispensable for adult erythropoiesis | Researchers | Basic research |
ResearchUnit: A Sweet Solution for Infant Transfusions? | Acker JP | 2014 | Blood.ca website | View ResearchUnit: A Sweet Solution for Infant Transfusions? | Other | Other |
Risks, benefits and the role of stakeholders in pathogen reduction technology | Newbold KB, Heddle NM, Lane SJ, Arnold E, Eyles J, Webert K | 2014 | Health Risk Soc | View Risks, benefits and the role of stakeholders in pathogen reduction technology | Other | Other |
A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing | Acker JP, Hansen AL, Kurach JD, Turner TR, Croteau I, Jenkins C | 2014 | Transfusion | View A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing | Blood operators | Benchmarking and standard setting |
Prophylactic platelet transfusions: should they be a treatment of the past? | Zeller MP, Al-Habsi KS, Heddle NM | 2014 | Curr Opin Hematol | View Prophylactic platelet transfusions: should they be a treatment of the past? | Health care providers | Clinical research |
Successful treatment with oseltamivir phosphate in a patient with chronic immune thrombocytopenia positive for anti-GPIb/IX autoantibody | Shao L, Wu Y, Zhou H, Qin P, Ni H, Peng J, Hou M | 2014 | Platelets | View Successful treatment with oseltamivir phosphate in a patient with chronic immune thrombocytopenia positive for anti-GPIb/IX autoantibody | Health care providers | Clinical research |
Alpha-1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis | McCurdy TR, Patrick AL, Eltringham-Smith LJ, Bhakta V, Sheffield WP, Fox-Robichaud AE | 2014 | Microcirculation | View Alpha-1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis | Researchers | Basic research |
Design, implementation, and evaluation of a knowledge translation intervention to increase organ donation after cardiocirculatory death in Canada: a study protocol | Squires JE, Grimshaw JM, Taljaard M, Linklater S, Chasse M, Shemie SD, Knoll GA | 2014 | Implement Sci | View Design, implementation, and evaluation of a knowledge translation intervention to increase organ donation after cardiocirculatory death in Canada: a study protocol | Researchers | Other |
Migration, proliferation and differentiation of cord blood mesenchymal stromal cells treated with histone deacetylase inhibitor valproic acid | Marquez-Curtis LA, Qiu Y, Xu A, Janowska-Wieczorek A | 2014 | Stem Cells Int | View Migration, proliferation and differentiation of cord blood mesenchymal stromal cells treated with histone deacetylase inhibitor valproic acid | Researchers | Basic research |
ResearchUnit: Pathogen Inactivation for Safer Blood Transfusion: What are the Limitations? | Schubert P | 2014 | Blood.ca website | View ResearchUnit: Pathogen Inactivation for Safer Blood Transfusion: What are the Limitations? | Other | Other |