Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials Lalu MM, McIntyre L, Pugliese C, Fergusson D, Winston BW, Marshall JC, Granton J, Stewart DJ, Canadian Critical Care Trials Group 2012 PLoS One View Researchers Clinical research
Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier Singh S, Dubinsky-Davidchik IS, Kluger R 2016 Org Biomol Chem View Researchers Basic research
The cell motility modulator Slit2 is a potent inhibitor of platelet function Patel S, Huang YW, Reheman A, Pluthero FG, Chaturvedi S, Mukovozov IM, Tole S, Liu GY, Li L, Durocher Y, Ni H, Kahr WH, Robinson LA 2012 Circulation View Researchers Basic research
Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils Campbell IK, Miescher S, Branch DR, Mott PJ, Lazarus AH, Han D, Maraskovsky E, Zuercher AW, Neschadim A, Leontyev D, McKenzie BS, Kasermann F 2014 J Immunol View Researchers Basic research
Vascular endothelial dysfunction in beta-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO Stoyanova E, Trudel M, Felfly H, Lemsaddek W, Garcia D, Cloutier G 2012 PLoS One View Researchers Basic research
Modelling the Need for New Blood Donors Following a Change in Deferral Period Blake J 2018 Industrial Engineering and Operations Management I View Researchers Clinical research
Assessing opportunities and challenges for establishing a national program to distribute cord blood for research Isasi R, Mastronardi C, Golder M, Allan D, Walker M, Halpenny M, Yang L, Elmoazzen H, Chargé S 2018 Transfusion View Researchers Other
GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out Lewis BJB, Leontyev D, Neschadim A, Blacquiere M, Branch DR 2018 Clin Exp Immunol View Researchers Basic research
ResearchUnit: Plasma: what's in the bag? Sheffield W, Jenkins C 2018 Blood.ca website View Researchers Basic research
Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques Scott BM, Sheffield WP 2020 Protein Sci View Researchers Basic research
Ironing out frequent blood donation Devine DV 2019 Lancet Haematol View Researchers New or improved product or process
Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype Almizraq R, Kipkeu B, Acker JP 2020 Transfusion View Researchers Basic research
An AI-Driven Predictive Modelling Framework to Analyze and Visualize Blood Product Transactional Data for Reducing Blood Products’ Discards Rad J, Cheng C, Quinn JG, Abidi S, Liwski R, Abidi SSR 2020 Artificial Intelligence in Medicine View Researchers New or improved product or process
Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate derivatives William N, Acker JP 2020 Cryobiology View Researchers Basic research
Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy Balitsky AK, Liu Y, Van der Meer PF, Heddle NM, Arnold DM 2021 Transfusion View Researchers Clinical research
SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada Saeed S, Drews SJ, Pambrun C, Yi Q-L, Osmond L, O'Brien SF 2021 Transfusion View Researchers Clinical research
Updated Understanding of Platelets in Thrombosis and Hemostasis: The Roles of Integrin PSI Domains and their Potential as Therapeutic Targets MacKeigan DT, Ni T, Shen C, Stratton TW, Ma W, Zhu G, Bhoria P, Ni H 2020 Cardiovasc Hematol Disord Drug Targets View Researchers Basic research
SARS-CoV-2 Virus-Like Particle Neutralizing Capacity in Blood Donors Depends on Serological Profile and Donor-Declared SARS-CoV-2 Vaccination History Drews SJ, Hu Q, Samson R, Abe KT, Rathod B, Colwill K, Gingras A-C, Yi Q-L, O’Brien SF, Mostafa HH 2022 Microbiol Spectr View Researchers Clinical research
National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies Holmberg JA, Henry SM, Burnouf T, Devine D, Marschner S, Boothby TC, Burger SR, Chou ST, Custer B, Blumberg N, Siegel DL, Spitalnik SL 2022 Transfusion View Researchers Benchmarking and standard setting
Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia Li N, Mahamad S, Parpia S, Iorio A, Foroutan F, Heddle NM, Hsia CC, Sholzberg M, Rimmer E, Shivakumar S, Sun HL, Refaei M, Hamm C, Arnold DM 2022 J Thromb Haemost View Researchers New or improved product or process
Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex Sask KN, Thong B, Goodarzynejad N, Berry LR, Chan AKC 2022 Biointerphases View Researchers Basic research
GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach Zeng L, Brignardello-Petersen R, Hultcrantz M, Mustafa RA, Murad MH, Iorio A, Traversy G, Akl EA, Mayer M, Schünemann HJ, Guyatt GH 2022 J Clin Epidemiol View Researchers Clinical research
A pH and thermosensitive choline phosphate-based delivery platform targeted to the acidic tumor microenvironment Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE 2014 Biomaterials View Researchers Basic research
Adhesion Molecules. Ni H 2013 Mechanisms in Hematology View Researchers Basic research
An investigation of red blood cell concentrate quality during storage in paediatric-sized polyvinylchloride bags plasticized with alternatives to di-2-ethylhexyl phthalate (DEHP) Serrano K, Levin E, Chen D, Hansen A, Turner TR, Kurach J, Reidel A, Boecker WF, Acker JP, Devine DV 2015 Vox Sang View Researchers Basic research
ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive Yu X, Yang X, Horte S, Kizhakkedathu JN, Brooks DE 2013 Chem Commun View Researchers Basic research
Cell-matrix interactions of Factor IX (FIX)-engineered human mesenchymal stromal cells encapsulated in RGD-alginate vs. Fibrinogen-alginate microcapsules Sayyar B, Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 Artif Cells Nanomed Biotechnol View Researchers Basic research
Comments on: Bernardo et al. 2016 (Blood)Working together to block alloimmunization Stowell SR 2016 Blood View Researchers Basic research
Diagnostic accuracy of IgG-specific versus polyspecific enzyme-linked immunoassays in heparin-induced thrombocytopenia: a systematic review and meta-analysis Husseinzadeh HD, Gimotty PA, Pishko AM, Buckley M, Warkentin TE, Cuker A 2017 J Thromb Haemost View Researchers Clinical research
Ebola virus VP35 blocks stress granule assembly Le Sage V, Cinti A, McCarthy S, Amorim R, Rao S, Daino GL, Tramontano E, Branch DR, Mouland AJ 2017 Virology View Researchers Basic research
Epigenetic regulation of endothelial-cell-mediated vascular repair Fraineau S, Palii CG, Allan DS, Brand M 2015 FEBS J View Researchers Other
Extended storage and glucose exhaustion are associated with apoptotic changes in platelets stored in additive solution Johnson L, Schubert P, Tan S, Devine DV, Marks DC 2015 Transfusion View Researchers Basic research
Fully automated decomposition of raman spectra into individual Pearson's type VII distributions applied to biological and biomedical samples Schulze HG, Atkins CG, Devine DV, Blades MW, Turner RF 2015 Appl Spectrosc View Researchers Basic research
How do I interpret a p value? O'Brien SF, Osmond L, Yi Q-L 2015 Transfusion View Researchers Other
Improved mouse models for the study of treatment modalities for immune-mediated platelet destruction Katsman Y, Foo AH, Leontyev D, Branch DR 2010 Transfusion View Researchers Basic research
Low levels of interleukin-10 in patients with transfusion-related acute lung injury Kapur R, Kim M, Rebetz J, Rondina MT, Porcelijn L, Semple JW 2017 Ann Transl Med View Researchers Clinical research
Microfluidic deformability analysis of the red cell storage lesion Matthews K, Myrand-Lapierre M-E, Ang RR, Duffy SP, Scott MD, Ma H 2015 J Biomech View Researchers New or improved product or process
Myasthenia gravis treated with autologous hematopoietic stem cell transplantation Bryant A, Atkins H, Pringle C, Allan D, Anstee G, Bence-Bruckler I, Hamelin L, Hodgins M, Hopkins HS, Huebsch L, McDiarmid S, Sabloff M, Sheppard D, Tay J, Bredeson C 2016 JAMA Neurol View Researchers Clinical research
Plasma and cryoprecipitate for transfusion Stanworth SJ, Tinmouth AT 2016 Rossi's Principles of Transfusion Medicine View Researchers Basic research
Polymeric Nanoparticle-Mediated Silencing of CD44 Receptor in CD34+ Acute Myeloid Leukemia Cells Gul-Uluda H, Valencia-Serna J, Kucharski C, Marquez-Curtis LA, Jiang X, Larratt L, Janowska-Wieczorek A, Uluda H 2014 Leukemia Res View Researchers Basic research
RhD Specific Antibodies Are Not Detectable in HLA-DRB1(*)1501 Mice Challenged with Human RhD Positive Erythrocytes Bernardo L, Denomme GA, Shah K, Lazarus AH 2014 Adv Hematol View Researchers Basic research
Severe platelet desialylation in a patient with glycoprotein Ib/IX antibody-mediated immune thrombocytopenia and fatal pulmonary hemorrhage Li J, Callum JL, Lin Y, Zhou Y, Zhu G, Ni H 2014 Haematologica View Researchers Clinical research
Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW 2016 Platelets View Researchers Basic research
45 - Alloimmune Thrombocytopenia Kaplan C, Bertrand G, Ni H 2019 Platelets (Fourth Edition) View Researchers New or improved product or process
Red blood cell antibody-induced anemia causes differential degrees of tissue hypoxia in kidney and brain Mistry N, Mazer CD, Sled JG, Lazarus AH, Cahill LS, Solish M, Zhou Y-Q, Romanova N, Hare AGM, Doctor A, Fisher JA, Brunt KR, Simpson JA, Hare GMT 2018 Am J Physiol Regul Integr Comp Physiol View Researchers Basic research
Evaluation of a hydrogel-based diagnostic approach for the point-of-care based detection of Neisseria gonorrhoeae Perera S, Taheri A, Khan N, Parti R, Stefura S, Skiba P, Acker J, Martin I, Kusalik A, Dillon J-A 2018 Antibiotics View Researchers New or improved product or process
Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains Spitalnik SL, Devine DV 2019 Transfusion View Researchers Other
Enhancing the pro-inflammatory anti-cancer T cell response via biomanufactured, secretome-based, immunotherapeutics Yang X, Kang N, Toyofuku WM, Scott MD 2018 Immunobiology View Researchers Basic research
Concentré de recherche: Améliorer les analyses de qualité réalisées sur les cellules souches destinées à la greffe Pineault N 2020 Blood.ca website View Researchers New or improved product or process
Gay and bisexual men’s views on reforming blood donation policy in Canada: a qualitative study Grace D, Gaspar M, Lessard D, Klassen B, Brennan DJ, Adam BD, Jollimore J, Lachowsky NJ, Hart TA 2019 BMC Public Health View Researchers Other