Our Research Publications
Updated November 2023
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Title | Authors | Year | Journal | Link to Article | Intended Audience Sort descending | Purpose |
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The role of inflammation in intravenous immune globulin-mediated hemolysis | Pendergrast J, Willie-Ramharack K, Sampson L, Laroche V, Branch DR | 2015 | Transfusion | View The role of inflammation in intravenous immune globulin-mediated hemolysis | Researchers | Clinical research |
Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis | Alexander PE, Barty R, Fei Y, Vandvik PO, Pai M, Siemieniuk RA, Heddle NM, Blumberg N, McLeod SL, Liu J, Eikelboom JW, Guyatt GH | 2016 | Blood | View Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis | Researchers | Clinical research |
ResearchUnit: A different way to look at red blood cell quality | Acker J | 2018 | Blood.ca website | View ResearchUnit: A different way to look at red blood cell quality | Researchers | Clinical research |
Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia | Huynh A, Arnold DM, Kelton JG, Smith JW, Horsewood P, Clare R, Guarné A, Nazy I | 2018 | J Thromb Haemost | View Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin-induced thrombocytopenia | Researchers | Basic research |
IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcgRIIA Disease-Associated Gene Variant | Kozicky LK, Menzies SC, Zhao ZY, Vira T, Harnden K, Safari K, Del Bel KL, Turvey SE, Sly LM | 2018 | Front Immunol | View IVIg and LPS Co-stimulation Induces IL-10 Production by Human Monocytes, Which Is Compromised by an FcgRIIA Disease-Associated Gene Variant | Researchers | Basic research |
What's in a name? Patient registration errors and their threat to transfusion safety | Ning S, Yan MTS, Downie H, Callum J | 2018 | Transfusion | View What's in a name? Patient registration errors and their threat to transfusion safety | Researchers | New or improved product or process |
Raman spectroscopy of stored red blood cell concentrate within sealed transfusion blood bags | Vardaki MZ, Atkins CG, Schulze HG, Devine DV, Serrano K, Blades MW, Turner RFB | 2018 | Analyst | View Raman spectroscopy of stored red blood cell concentrate within sealed transfusion blood bags | Researchers | New or improved product or process |
Defocused Spatially Offset Raman Spectroscopy in Media of Different Optical Properties for Biomedical Applications Using a Commercial Spatially Offset Raman Spectroscopy Device | Vardaki MZ, Devine DV, Serrano K, Simantiris N, Blades MW, Piret JM, Turner RFB | 2020 | Appl Spectrosc | View Defocused Spatially Offset Raman Spectroscopy in Media of Different Optical Properties for Biomedical Applications Using a Commercial Spatially Offset Raman Spectroscopy Device | Researchers | New or improved product or process |
IgG3 anti-Kell allotypic variation results in differential antigen binding and phagocytosis | Cen SY, Holton MB, Binnington B, Denomme GA, Howie HL, Lebedev JN, Zimring JC, Branch DR | 2020 | Transfusion | View IgG3 anti-Kell allotypic variation results in differential antigen binding and phagocytosis | Researchers | Basic research |
Not all red cell concentrate units are equivalent: international survey of processing and in vitro quality data | Shih AW, Apelseth TO, Cardigan R, Marks DC, Bégué S, Greinacher A, de Korte D, Seltsam A, Shaz BH, Wikman A, Barty RL, Heddle NM, Acker JP, The QMiP Investigators on behalf of the Biomedical Excellence for Safer Transfusion Collaborative | 2019 | Vox Sang | View Not all red cell concentrate units are equivalent: international survey of processing and in vitro quality data | Researchers | Benchmarking and standard setting |
Canada's MSM Research Program - producing and mobilizing knowledge | Chargé S, Haw J | 2020 | Transfusion Today | Researchers | MSM research | |
Emerging use of machine learning and advanced technologies to assess red cell quality | Sebastian JA, Kolios MC, Acker JP | 2020 | Transfus Apher Sci | View Emerging use of machine learning and advanced technologies to assess red cell quality | Researchers | New or improved product or process |
Objective assessment of stored blood quality by deep learning | Doan M, Sebastian JA, Caicedo JC, Siegert S, Roch A, Turner TR, Mykhailova O, Pinto RN, McQuin C, Goodman A, Parsons MJ, Wolkenhauer O, Hennig H, Singh S, Wilson A, Acker JP, Rees P, Kolios MC, Carpenter AE | 2020 | PLoS Pathog | View Objective assessment of stored blood quality by deep learning | Researchers | New or improved product or process |
Research Unit: Machine learning throws away the buckets to better understand red blood cell quality | Acker JP | 2020 | Blood.ca website | View Research Unit: Machine learning throws away the buckets to better understand red blood cell quality | Researchers | Basic research |
Transfusion septic reactions involving platelet concentrates contaminated with Citrobacter koseri | Ramirez-Arcos S | 2020 | Ann Blood | View Transfusion septic reactions involving platelet concentrates contaminated with Citrobacter koseri | Researchers | Clinical research |
High sub-zero organ preservation: A paradigm of nature-inspired strategies | William N, Acker JP | 2021 | Cryobiology | View High sub-zero organ preservation: A paradigm of nature-inspired strategies | Researchers | Basic research |
Complete Genome Sequence of Staphylococcus aureus PS/BAC/169/17/W, Isolated from a Contaminated Platelet Concentrate in England | Paredes C, Chi SI, Flint A, Weedmark K, McDonald C, Bearne J, Ramirez-Arcos S, Pagotto F, Baltrus DA | 2021 | Microbiol Resour Announc | View Complete Genome Sequence of Staphylococcus aureus PS/BAC/169/17/W, Isolated from a Contaminated Platelet Concentrate in England | Researchers | Benchmarking and standard setting |
Double high-dose immunoglobulin for ChAdOx1 nCov-19 vaccine-induced immune thrombotic thrombocytopenia | Huang CT, Hsu SY, Wang CH, Tseng WJ, Yang CY, Ng CJ, Warkentin TE, Cheng MH | 2021 | Thromb Res | View Double high-dose immunoglobulin for ChAdOx1 nCov-19 vaccine-induced immune thrombotic thrombocytopenia | Researchers | Clinical research |
Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies | Gajic-Veljanoski O, Li C, Schaink AK, Guo J, Shehata N, Charames GS, de Vrijer B, Clarke G, Pechlivanoglou P, Okun N, Kandel R, Dooley J, Higgins C, Ng V, Sikich N | 2022 | Transfusion | View Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies | Researchers | Clinical research |
The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults | Asamoah-Boaheng M, Goldfarb DM, Karim ME, O’Brien SF, Wall N, Drews SJ, Barakauskas V, Jassem AN, Grunau B | 2022 | J Infect Dis | View The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults | Researchers | Clinical research |
Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study | Cognasse F, Hamzeh Cognasse H, Eyraud MA, Prier A, Arthaud CA, Tiberghien P, Begue S, de Korte D, Gouwerok E, Greinacher A, Aurich K, Noorman F, Dumont L, Kelly K, Cloutier M, Bazin R, Cardigan R, Huish S, Smethurst P, Devine D, Schubert P, Johnson L, Marks DC, Biomedical Excellence for Safer Transfusion Collaborative | 2023 | Transfusion | View Assessment of the soluble proteins HMGB1, CD40L and CD62P during various platelet preparation processes and the storage of platelet concentrates: The BEST collaborative study | Researchers | Basic research |
HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada | Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA | 2022 | Transfusion | View HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada | Researchers | MSM research |
Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study | Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative | 2022 | Transfusion | View Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study | Researchers | Benchmarking and standard setting |
A lab-on-chip for malaria diagnosis and surveillance | Taylor BJ, Howell A, Martin KA, Manage DP, Gordy W, Campbell SD, Lam S, Jin A, Polley SD, Samuel RA, Atrazhev A, Stickel AJ, Birungi J, Mbonye AK, Pilarski LM, Acker JP, Yanow SK | 2014 | Malar J | View A lab-on-chip for malaria diagnosis and surveillance | Researchers | Basic research |
Applications of Liposomes in Biopreservation | Da Silveira Cavalcante L, Holovati J, Acker J | 2016 | Multiscale technologies for cryomedicine: implementation from nano to macroscale | View Applications of Liposomes in Biopreservation | Researchers | Basic research |
Biomonitoring of Arsenic in Urine and Saliva of Children Playing on Playgrounds Constructed from Chromated Copper Arsenate-Treated Wood | Lew K, Acker JP, Gabos S, Le XC | 2010 | Environ Sci Technol | View Biomonitoring of Arsenic in Urine and Saliva of Children Playing on Playgrounds Constructed from Chromated Copper Arsenate-Treated Wood | Researchers | Other |
Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors | Ghobadloo SM, Balcerzak AK, Gargaun A, Muharemagic D, Mironov GG, Capicciotti CJ, Briard JG, Ben RN, Berezovski MV | 2014 | Sci Rep | View Carbohydrate-based ice recrystallization inhibitors increase infectivity and thermostability of viral vectors | Researchers | Basic research |
Emerging Role for Use of Liposomes in the Biopreservation of Red Blood Cells | Holovati JL, Acker JP | 2011 | Transfus Med Hemother | View Emerging Role for Use of Liposomes in the Biopreservation of Red Blood Cells | Researchers | Basic research |
Fibronectin: extra domain brings extra risk? | Wang Y, Ni H | 2015 | Blood | View Fibronectin: extra domain brings extra risk? | Researchers | Other |
Immunocamouflage of latex surfaces by grafted methoxypoly(ethylene glycol) (mPEG): proteomic analysis of plasma protein adsorption | Le Y, Li L, Wang D, Scott MD | 2012 | Sci China Life Sci | View Immunocamouflage of latex surfaces by grafted methoxypoly(ethylene glycol) (mPEG): proteomic analysis of plasma protein adsorption | Researchers | Basic research |
Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa | Sheffield WP, Eltringham-Smith LJ | 2011 | BMC Biotechnol | View Incorporation of albumin fusion proteins into fibrin clots in vitro and in vivo: comparison of different fusion motifs recognized by factor XIIIa | Researchers | Basic research |
Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells | Bakkour S, Acker JP, Chafets DM, Inglis HC, Norris PJ, Lee TH, Busch MP | 2016 | Vox Sang | View Manufacturing method affects mitochondrial DNA release and extracellular vesicle composition in stored red blood cells | Researchers | Basic research |
Mitochondria and membrane cryoinjury in micropatterned cells: Effects of cell-cell interactions | Tchir J, Acker JP | 2010 | Cryobiology | View Mitochondria and membrane cryoinjury in micropatterned cells: Effects of cell-cell interactions | Researchers | Basic research |
Platelet immunology in China: research and clinical applications | Wu G, Zhou Y, Li L, Zhong Z, Li H, Li H, Yu M, Shen W, Ni H | 2017 | Transfus Med Rev | View Platelet immunology in China: research and clinical applications | Researchers | Clinical research |
Renin-Angiotensin System Blockade and Long-term Clinical Outcomes in Kidney Transplant Recipients: A Meta-analysis of Randomized Controlled Trials | Hiremath S, Fergusson DA, Fergusson N, Bennett A, Knoll GA | 2017 | Am J Kidney Dis | View Renin-Angiotensin System Blockade and Long-term Clinical Outcomes in Kidney Transplant Recipients: A Meta-analysis of Randomized Controlled Trials | Researchers | Clinical research |
Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier | Singh S, Dubinsky-Davidchik IS, Kluger R | 2016 | Org Biomol Chem | View Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier | Researchers | Basic research |
The cell motility modulator Slit2 is a potent inhibitor of platelet function | Patel S, Huang YW, Reheman A, Pluthero FG, Chaturvedi S, Mukovozov IM, Tole S, Liu GY, Li L, Durocher Y, Ni H, Kahr WH, Robinson LA | 2012 | Circulation | View The cell motility modulator Slit2 is a potent inhibitor of platelet function | Researchers | Basic research |
Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils | Campbell IK, Miescher S, Branch DR, Mott PJ, Lazarus AH, Han D, Maraskovsky E, Zuercher AW, Neschadim A, Leontyev D, McKenzie BS, Kasermann F | 2014 | J Immunol | View Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils | Researchers | Basic research |
Vascular endothelial dysfunction in beta-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO | Stoyanova E, Trudel M, Felfly H, Lemsaddek W, Garcia D, Cloutier G | 2012 | PLoS One | View Vascular endothelial dysfunction in beta-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO | Researchers | Basic research |
Modelling the Need for New Blood Donors Following a Change in Deferral Period | Blake J | 2018 | Industrial Engineering and Operations Management I | View Modelling the Need for New Blood Donors Following a Change in Deferral Period | Researchers | Clinical research |
Assessing opportunities and challenges for establishing a national program to distribute cord blood for research | Isasi R, Mastronardi C, Golder M, Allan D, Walker M, Halpenny M, Yang L, Elmoazzen H, Chargé S | 2018 | Transfusion | View Assessing opportunities and challenges for establishing a national program to distribute cord blood for research | Researchers | Other |
GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out | Lewis BJB, Leontyev D, Neschadim A, Blacquiere M, Branch DR | 2018 | Clin Exp Immunol | View GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out | Researchers | Basic research |
ResearchUnit: Plasma: what's in the bag? | Sheffield W, Jenkins C | 2018 | Blood.ca website | View ResearchUnit: Plasma: what's in the bag? | Researchers | Basic research |
Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques | Scott BM, Sheffield WP | 2020 | Protein Sci | View Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques | Researchers | Basic research |
Ironing out frequent blood donation | Devine DV | 2019 | Lancet Haematol | View Ironing out frequent blood donation | Researchers | New or improved product or process |
Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype | Almizraq R, Kipkeu B, Acker JP | 2020 | Transfusion | View Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype | Researchers | Basic research |
An AI-Driven Predictive Modelling Framework to Analyze and Visualize Blood Product Transactional Data for Reducing Blood Products’ Discards | Rad J, Cheng C, Quinn JG, Abidi S, Liwski R, Abidi SSR | 2020 | Artificial Intelligence in Medicine | View An AI-Driven Predictive Modelling Framework to Analyze and Visualize Blood Product Transactional Data for Reducing Blood Products’ Discards | Researchers | New or improved product or process |
Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate derivatives | William N, Acker JP | 2020 | Cryobiology | View Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate derivatives | Researchers | Basic research |
Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy | Balitsky AK, Liu Y, Van der Meer PF, Heddle NM, Arnold DM | 2021 | Transfusion | View Exploring the components of bleeding outcomes in transfusion trials for patients with hematologic malignancy | Researchers | Clinical research |
SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada | Saeed S, Drews SJ, Pambrun C, Yi Q-L, Osmond L, O'Brien SF | 2021 | Transfusion | View SARS-CoV-2 seroprevalence among blood donors after the first COVID-19 wave in Canada | Researchers | Clinical research |