Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Severe hemolytic disease of the fetus and newborn due to allo-anti-D in a patient with a partial DEL phenotype arising from the variant allele described as RHD*148+1T (RHD*01EL.31) Turley E, McGowan EC, Hyland CA, Schoeman EM, Flower RL, Skoll A, Delisle MF, Nelson T, Clarke G, Au N 2018 Transfusion View Researchers Clinical research
Age-Separated RBCs Show Changes in Oxygen Carrying Capacity and Rigidity During Hypothermic Storage Mykhailova O, Li W, Acker J 2019 Probl Cryobiol Cryomed View Researchers Basic research
Decoding the metabolic landscape of pathophysiological stress-induced cell death in anucleate red blood cells Nemkov T, Qadri SM, Sheffield WP, D'Alessandro A 2020 Blood Transfus View Researchers Basic research
Human leukocyte antigen-G upregulates immunoglobulin-like transcripts and corrects dysfunction of immune cells in immune thrombocytopenia Li X, Sheng Z, Sun Y, Wang Y, Xu M, Zhang Z, Li H, Shao L, Zhang Y, Yu J, Ma C, Gao C, Hou M, Ni H, Peng J, Ma J, Feng Q 2020 Haematologica View Researchers Basic research
Multi-laboratory assay for harmonization of enumeration of viable CD34+ and CD45+ cells in frozen cord blood units Fournier D, Lewin A, Simard C, Trépanier P, Néron S, Ballerini L, Codinach M, Elmoazzen H, Halpenny M, Kogler G, Liedtke S, Louis I, Molluna CA, Pineault N, Prasath A, Querol S, Saccardi R, Sutherland DR, Thérien C, Urbani S 2020 Cytotherapy View Researchers Benchmarking and standard setting
Using umbilical cord blood for regenerative therapy: Proof or promise? Allan DS 2020 Stem Cells View Researchers Clinical research
Concentré de recherche: Les dons de sang effectués avant la grossesse sont sans danger pour les mères et les bébés Chassé M 2020 Blood.ca website Researchers Clinical research
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials Lawati KA, Sharif S, Maqbali SA, Rimawi HA, Petrosoniak A, Belley-Cote EP, Sharma SV, Morgenstern J, Fernando SM, Owen JJ, Zeller M, Quinlan D, Alhazzani W, Rochwerg B 2021 Intensive Care Med Researchers Clinical research
Identification of an alpha-1 antitrypsin variant with enhanced specificity for factor XIa by phage display, bacterial expression, and combinatorial mutagenesis Bhakta V, Hamada M, Nouanesengsy A, Lapierre J, Perruzza DL, Sheffield WP 2021 Sci Rep View Researchers Basic research
Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion Leatherdale A, Parker DA, Tasneem S, Wang Y, Bihan D, Bonna A, Hamaia SW, Gross PL, Ni H, Doble BW, Lillicrap D, Farndale RW, Hayward CPM 2021 J Thromb Haemost View Researchers Basic research
Research initiatives of blood services worldwide in response to the covid-19 pandemic O'Brien SF, Lieshout-Krikke RW, Lewin A, Erikstrup C, Steele WR, Uzicanin S, Custer B, the Surveillance RA, Policy Sub-group of the ISBT Transfusion Transmitted Infectious Diseases Working Party 2021 Vox Sang View Researchers Clinical research
Systematic review and meta-analysis of outcomes in patients with suspected pulmonary embolism Patel P, Patel P, Bhatt M, Braun C, Begum H, Nieuwlaat R, Khatib R, Martins CC, Zhang Y, Etxeandia-Ikobaltzeta I, Varghese J, Alturkmani H, Bahaj W, Baig M, Kehar R, Mustafa A, Ponnapureddy R, Sethi A, Thomas M, Wooldridge D, Lim W, Bates SM, Lang E, Le Gal G, Haramati LB, Kline J, Righini M, Wiercioch W, Schünemann H, Mustafa RA 2021 Blood Adv View Researchers Clinical research
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIb? Li BX, Dai X, Xu XR, Adili R, Neves MAD, Lei X, Shen C, Zhu G, Wang Y, Zhou H, Hou Y, Ni T, Pasman Y, Yang Z, Qian F, Zhao Y, Gao Y, Liu J, Teng M, Marshall AH, Cerenzia EG, Li ML, Ni H 2021 Sci Rep View Researchers Clinical research
Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects Huynh A, Arnold DM, Smith JW, Moore JC, Zhang A, Chagla Z, Harvey BJ, Stacey HD, Ang JC, Clare R, Ivetic N, Chetty VT, Bowdish DME, Miller MS, Kelton JG, Nazy I 2021 Viruses View Researchers Clinical research
An international comparison of HIV prevalence and incidence in blood donors and general population: a BEST Collaborative study Germain M, Grégoire Y, Custer BS, Goldman M, Bravo M, Kamel H, Davison K, Field S, van den Hurk K, van de Laar TJW, Irving DO, Jones A, Liumbruno G, Morley S, O’Brien SF, Pillonel J, Steinsvåg CT, Takanashi M, Tsuno NH, Vesga Carasa MA, Wendel S, Vassallo RR, Tiberghien P, for the BEST Collaborative 2021 Vox Sang View Researchers Benchmarking and standard setting
Characterizing Frailty In Myeloproliferative Neoplasms: results from the ORCHID study Chornenki NLJ, Siegal DM, Qamar K, Woolgar S, Rangarajan S, Karampatos S, Leong DP, Hillis CM 2022 Leuk Res View Researchers Clinical research
Sensitivity of the Elecsys Nucleocapsid Assay for the Detection of Preceding SARS-CoV-2 Infections Grunau B, Tom J, Asamoah-Boaheng M, O’Brien SF, Drews SJ, Sediqi S, Lavoie PM, Barakauskas V, Goldfarb DM 2022 Open Forum Infect Dis View Researchers Basic research
Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency-first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository Kumar R, Bakeer N, Dawson J, Al-Mughairy A, Stanek J, Dunn A, Male C, Chan A, Williams S 2023 J Thromb Haemost View Researchers Basic research
Altered timing of riboflavin and ultraviolet light pathogen inactivation improves platelet in vitro quality Schubert P, Culibrk B, Karwal S, Serrano K, Levin E, Yi Q, Thiele T, Greinacher A, Marschner S, Devine DV 2017 Transfusion View Researchers New or improved product or process
Apixaban for treatment of confirmed heparin-induced thrombocytopenia: a case report and review of literature Ezekwudo DE, Chacko R, Gbadamosi B, Batool S, Gaikazian S, Warkentin TE, Sheppard JI, Jaiyesimi I 2017 Exp Hematol Oncol View Researchers Clinical research
Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors D'Aragon F, Dhanani S, Lamontagne F, Cook DJ, Burns K, Akhtar A, Chasse M, Frenette AJ, Keenan S, Lize JF, Kutsogiannis DJ, Kramer A, Hand LE, Arseneau E, Masse MH, Ribic C, Ball I, Baker A, Boyd G, Rochwerg B, Healey A, Hanna S, Guyatt GH, Meade MO 2017 BMJ Open View Researchers Clinical research
Concentré de recherche: Un modèle de changement : prédiction de l'impact d'améliorations à  l'échelle du système Blake J 2018 Blood.ca website View Researchers Basic research
Determination of the biological form of human cytomegalovirus DNA in the plasma of solid-organ transplant recipients Tong Y, Pang XL, Mabilangan C, Preiksaitis JK 2017 J Infect Dis View Researchers Clinical research
Eltrombopag after allogeneic haematopoietic cell transplantation in a case of poor graft function and systematic review of the literature Dyba J, Tinmouth A, Bredeson C, Matthews J, Allan DS 2016 Transfus Med View Researchers Clinical research
Fibronectin maintains the balance between hemostasis and thrombosis Wang Y, Ni H 2016 Cell Mol Life Sci View Researchers Basic research
Hope for the Best, but Prepare for the Worst Blake J, Nemergut EC 2014 Anesth Analg View Researchers New or improved product or process
Impact of blood manufacturing and donor characteristics on membrane water permeability and in vitro quality parameters during hypothermic storage of red blood cells Alshalani A, Howell A, Acker JP 2018 Cryobiology View Researchers Basic research
Innate and adaptive immunity in immune thrombocytopenia Lazarus AH, Semple JW, Cines DB 2013 Semin Hematol View Researchers Clinical research
Laboratory management of perinatal patients with apparently "new" anti-D Hannon J, Clarke G 2016 Immunohematology View Researchers Basic research
Mechanistic properties of intravenous immunoglobulin in murine immune thrombocytopenia: support for Fc?RIIB falls by the wayside Crow AR, Lazarus AH 2016 Semin Hematol View Researchers Basic research
O-aryl-glycoside ice recrystallization inhibitors as novel cryoprotectants: A structure-function study Capicciotti CJ, Mancini RS, Turner TR, Koyama T, Alteen MG, Doshi M, Inada T, Acker JP, Ben RN 2016 ACS Omega View Researchers Basic research
Rationale and design of platelet transfusions in haematopoietic stem cell transplantation: the PATH pilot study Tay J, Allan D, Beattie S, Bredeson C, Fergusson D, Maze D, Sabloff M, Thavorn K, Tinmouth A 2016 BMJ Open View Researchers Clinical research
The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia Arnold DM, Lauzier F, Albert M, Williamson D, Li N, Zarychanski R, Doig C, McIntyre L, Freitag A, Crowther M, Saunders L, Clarke F, Bellomo R, Qushmaq I, Lopes R, Heels-Ansdell D, Webert K, Cook D 2017 Res Pract Thromb Haemost View Researchers Clinical research
The Ins and Outs of Hematopoietic Stem Cells: Studies to Improve Transplantation Outcomes Marquez-Curtis LA, Turner AR, Sridharan S, Ratajczak MZ, Janowska-Wieczorek A 2011 Stem Cell Rev View Researchers Basic research
Value of MMA crossmatch? Tong TN, Cserti-Gazdewich CM, Branch DR 2016 Transfus Med View Researchers Basic research
Peri-Operative Eltrombopag or Immune Globulin for Patients with Immune Thrombocytopaenia (The Bridging ITP Trial): Methods and Rationale Arnold D, Jamula E, Heddle N, Cook R, Hsia C, Sholzberg M, Lin Y, Kassis J, Blostein M, Larratt L, Amini S, Schipperus M, Carruthers J, Lane S, Li N, G. Kelton J 2019 Thromb Haemost View Researchers Clinical research
International survey on the impact of parasitic infections: frequency of transmission and current mitigation strategies Leiby DA, O'Brien SF, Wendel S, Nguyen ML, Delage G, Devare SG, Hardiman A, Nakhasi HL, Sauleda S, Bloch EM, WPTTID Subgroup on Parasites 2019 Vox Sang View Researchers Clinical research
Thermal expansion of substrate may affect adhesion of Chinese hamster fibroblasts to surfaces during freezing Rutt T, Eskandari N, Zhurova M, Elliott JAW, McGann LE, Acker JP, Nychka JA 2019 Cryobiology View Researchers Basic research
Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay Warkentin TE, Arnold DM, Kelton JG, Sheppard J-AI, Smith JW, Nazy I 2018 Chest View Researchers Basic research
The effect of tantalum incorporation on the physical and chemical properties of ternary silicon–calcium–phosphorous mesoporous bioactive glasses Mendonca A, Rahman MS, Alhalawani A, Rodriguez O, Gallant RC, Ni H, Clarkin OM, Towler MR 2019 J Biomed Mater Res Part B Appl Biomater View Researchers Basic research
International Forum on Occult hepatitis B infection and transfusion safety Seed CR, Allain J-P, Lozano M, Laperche S, Gallian P, Gross S, Kwon S-Y, Oh EY, Kim JN, Chua SS, Lam S, Ang AL, Tsoi W-C, Hewitt PE, Davison KL, Tettmar K, O'Flaherty N, Boland F, Williams P, Pomeroy L, Wendel S, Fachini R, Scuracchio P, Carminato P, Fearon M, O'Brien SF, Delage G, Kiely P, Hoad V, Matsubayashi K, Satake M, Taira R, Stramer SL, Sauleda S, Bes M, Piron M, El Ekiaby M, Vermeulen M, Levi?nik Stezinar S, Nograšek P, Jarvis LM, Petrik J, Charlewood R, Flanagan P, Grabarczyk P, Kopacz A, ??towska M, Seifried E, Schmidt M 2019 Vox Sang View Researchers Benchmarking and standard setting
Platelet physiology and immunology: pathogenesis and treatment of classical and non-classical fetal and neonatal alloimmune thrombocytopenia Chen ZY, Oswald BE, Sullivan JA, Dahmani FZ, Pasman Y, Liu Z, Chen P, Ni H 2019 Ann Blood View Researchers Basic research
The systematic use of evidence-based methodologies and technologies enhances shared decision-making in the 2018 International Consensus Conference on Patient Blood Management Van Remoortel H, Aranko K, Mueller MM, De Buck E, Devine D, Folléa G, Meybohm P, Tiberghien P, Wood EM, Vandekerckhove P, Seifried E 2020 Vox Sang View Researchers Benchmarking and standard setting
Age-Specific SARS-CoV-2 Infection Fatality and Case Identification Fraction in Ontario, Canada Fisman DN, Drews SJ, Tuite AR, O’Brien SF 2020 medRxiv View Researchers Clinical research
Characterizing the ability of an ice recrystallization inhibitor to improve platelet cryopreservation Waters L, Ben R, Acker JP, Padula MP, Marks DC, Johnson L 2020 Cryobiology View Researchers New or improved product or process
Crosstalk Between Platelets and Microbial Pathogens Li C, Li J, Ni H 2020 Front Immunol View Researchers Basic research
Evidence for sustained mucosal and systemic antibody responses to SARS-CoV-2 antigens in COVID-19 patients Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yun YF, Marin LG, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, J.McGeer A, Gommerman JL, Gingras A-C 2020 medRxiv View Researchers Basic research
Safety and efficacy of self-administered romiplostim in patients with immune thrombocytopenia: Results of an integrated database of five clinical trials Kuter DJ, Arnold DM, Rodeghiero F, Janssens A, Selleslag D, Bird R, Newland A, Mayer J, Wang K, Olie R 2020 Am J Hematol View Researchers Clinical research
Psychometric Evaluation of ITP Life Quality Index (ILQI) in a Global Survey of Patients with Immune Thrombocytopenia Viana R, D'Alessio D, Grant L, Cooper N, Arnold D, Morgan M, Provan D, Cuker A, Hill QA, Tomiyama Y, Ghanima W 2021 Adv Ther View Researchers Clinical research
Risk of transfusion-transmitted Babesia microti in Canada O'Brien SF, Drews SJ, Yi Q-L, Bloch EM, Ogden NH, Koffi JK, Lindsay LR, Gregoire Y, Delage G 2021 Transfusion View Researchers Benchmarking and standard setting