Our Funded Research Projects

Updated April 2024

Title Principal Investigator / Supervisor Program Sort descending Project Start Date Project End Date Total $ Awarded
Can pre-operative anemia be timely identified and optimized in patients awaiting primary arthroplasty surgery? A randomized clinical trial Principal Investigator: GRAMMATOPOULOS, George

Co-Investigator(s) / Trainee: FERGUSSON, Dean, RAMSAY, Tim, TINMOUTH, Alan, GAGNE, Sylvain, MACK, Johnathan, BELZILE, Etienne, BEALE, Paul, THAVORN, Kednapa, TOUCHIE, Donna, GERMAIN, Genevieve, LAROCHE, Vincent
Intramural Research Grant Program 276081.0
Small molecule drug development of phagocytosis inhibitors Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: KOTRA, Lakshmi, P.
Intramural Research Grant Program 428468.4
Translating novel clotting factor X function to treat thrombosis Principal Investigator: PRYZDIAL, Ed

Co-Investigator(s) / Trainee: MACVICAR, Brian, SHEFFIELD, William
Intramural Research Grant Program 369052.0
Human monoclonal CD44 antibodies as potential IVIg replacements Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program 336000.0
Anti-GPIb- and anti-GPIIbIIIa- mediated immune thrombocytopenia: Mechanisms and actions of intravenous IgG (IVIG) and alternative therapies Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: LAZARUS, Alan, BRANCH, Donald
Intramural Research Grant Program 412010.3
Revisiting the universal donor: Does exposure to O blood products affect patient outcomes? Principal Investigator: ARNOLD, Donald

Co-Investigator(s) / Trainee: ACKER, Jason, BUCKSTEIN, Rena, CALLUM, Jeannie, COOK, Richard, HEDDLE, Nancy, SOLH, Ziad, WEBERT, Kathryn, BARTY, Rebecca, LEBER, Brian, LALIT, Saini
Intramural Research Grant Program 378365.0
Plasma versus plasma protein concentrate transfusion for coagulopathic control Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program 224417.0
Fc receptors and IVIg in ITP Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, LIN, Yulia, CALLUM, Jeannie, SHOLZBERG, Michelle, NI, Heyu
Intramural Research Grant Program 432000.0
Mechanisms of erythrocyte antibody-mediated immune suppression Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu, SEMPLE, John
Intramural Research Grant Program 400000.0
A multifaceted intervention to optimize red blood cell transfusion practice in two provinces Principal Investigator: WEBERT, Kathryn

Co-Investigator(s) / Trainee: NAHIRNIAK, Susan, CALLUM, Jeannie, LIN, Yulia, ZELLER, Michelle
Intramural Research Grant Program 332942.0
IN-TRUST: Using a transfusion database to explore the immune-modulatory impacts of blood transfusion and the clinical impacts of blood processing changes Principal Investigator: NING, Shuoyan

Co-Investigator(s) / Trainee: ARNOLD, Donald, ZELLER, Michelle, ACKER, Jason, LI, Na, HEDDLE, Nancy, HILLIS, Christopher, ROCHWERG, Bram, SYED, Summer
Intramural Research Grant Program 270352.1
RBC hemolysis and cellular effector mechanisms (RHANCEM) Principal Investigator: BRANCH, Donald

Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, PENDERGRAST,Jacob, CALLUM, Jeannie, YI, Qilong
Intramural Research Grant Program 399927.3
Optimization of monoclonal anti-erythrocyte antibodies for improved immunoprophylaxis in a murine model Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: NI, Heyu
Intramural Research Grant Program 400000.0
Canadian cord blood banking: Legal and policy responses Principal Investigator: CAULFIELD, Timothy

Co-Investigator(s) / Trainee: MURDOCH, Blake, MARCON, Alessandro
James Kreppner Award Program 50000.0
Of skin, sperm, and blood: A comparative analysis of exemptions in Canadian human tissue legislation Principal Investigator: CATTAPAN, Alana

Co-Investigator(s) / Trainee: VON TIGERSTROM, Barbara, NELSON, Eric, DAWSON, Rosanne
James Kreppner Award Program 43275.0
The role of stakeholder trust in OTDT policy change: public and professional attitudes to ante-mortem interventions in organ donation Principal Investigator: CHANDLER, Jennifer

Co-Investigator(s) / Trainee: McKAY, Lindsey
James Kreppner Award Program 50000.0
COVID-19 vaccination refusal and access to transplantation: an ethical conundrum. A legal analysis and a qualitative study with key stakeholders Principal Investigator: FORTIN, Marie-Chantal

Co-Investigator(s) / Trainee: CHANDLER, Jennifer, GILL, Justin, GOLDBERG, Aviva, GRUBEN, Vanessa
James Kreppner Award Program 49952.0
Determining potential policy solutions for normothermic regional perfusion in organ donation in Canada through analysis and resolution of two key ethical challenges Principal Investigator: WEIJER, Charles

Co-Investigator(s) / Trainee: BADENOCH, Heather, BASMAJI, John, BRAHMANIA, Mayur, CHANDLER, Jennifer, HEALEY, Andrew, LINGARD, Lorelei, MURPHY, Nicholas, OTT, Mary, SHEMIE, Sam, SKARO, Anton, SLESSAREV, Marat
James Kreppner Award Program 50000.0
Legal and policy strategies to optimize organ donation in Alberta Principal Investigator: TOEWS, Maeghan

Co-Investigator(s) / Trainee:
James Kreppner Fellowship Program 150000.0
Organ donation in Canada: Engaging with stakeholders and proposing solutions to current legal and ethical challenges Principal Investigator: GRUBEN, Vanessa

Co-Investigator(s) / Trainee:
James Kreppner Fellowship Program 150000.0
Prospective observational study of organ deceased donor management in 3 ICUs - a pilot study (the DONATE pilot study) Principal Investigator: MEADE, Maureen

Co-Investigator(s) / Trainee: D'ARAGON, Frederick, RIBIC, Christine, SHARPE, Michael, BALL, Ian, WILLIAMSON, David, DHANANI, Sonny, HANNA, Steven
Kenneth J. Fyke Award Program 89555.1
Developing a Canadian policy on the responsible use of umbilical cord blood for proven indications in regenerative therapy Principal Investigator: ALLAN, David

Co-Investigator(s) / Trainee: HUTTON, Brian, CAULFIELD, Timothy
Kenneth J. Fyke Award Program 100000.0
Canadians’ attitudes and opinions regarding cardiac donation after cardiocirculatory death: A mixed-methods study Principal Investigator: BALL, Ian

Co-Investigator(s) / Trainee: WEISS, Matt, D'ARAGON, Fred, PARSONS LEIGH, Jenna, HONARMAND, Kimia, BASMAJI, John, SIBBALD, Robert
Kenneth J. Fyke Award Program 95929.0
The pan-Canadian immunoglobulin database: Enabling utilization reporting and personalized treatment using data mining techniques for immunoglobulin Principal Investigator: LI, Na

Co-Investigator(s) / Trainee: DOWN, Douglas, CHIANG, Fei, LEE, Joon, HEDDLE, Nancy, ARNOLD, Donald, CALLUM, Jeannie, SIDHU, Davinder, BARTY, Rebecca
Kenneth J. Fyke Award Program 100000.0
Evaluating transfusion medicine patterns of practice across GEMINI sites Principal Investigator: CALLUM, Jeannie

Co-Investigator(s) / Trainee: ARNOLD, Donald, VERMA, Amol, SRIVASTAVA, Siddhartha, CHENG, Calvino, ESMAIL, Tariq, DESVEAUX, Laura, TYRYSHKIN, Kathrin, KARKOUTI, Keyvan, LADHA, Karim, LI, Na, PAVENSKI, Katerina, PENDERGRAST, Jacob, PRESSEAU, Justin, SCHNEIDER, Henry, SHEHATA, Nadine, SHIH, Andrew, THIRUMURTHY, Harsha, BREHAUT, Jamie, RAZAK, Fahad, MCLCEARY, Nicola, ZUCKERMAN, Jesse
Kenneth J. Fyke Award Program 98822.0
Assessing the acceptability and feasibility of a plasma donation program for gbMSM in Montréal from the point of view of cis and trans gbMSM, volunteers from Héma-Québec, current donors, and plasma product recipients Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, HAW, Jennie, MONTEITH, Kenneth, MYHAL, Geneviève, PRESSEAU, Justin, PIRNAT, Bojan, LAPIERRE, Don
MSM Plasma Program 390970.0
The Calgary Plasma Study: feasibility of implementing source plasma donation with alternative screening eligibility criteria for men who have sex with men Principal Investigator: PRESSEAU, Justin

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, FOSTER, Terrie, VESNAVER, Elisabeth, GERMAIN, Marc, ROSSER, Andrew, LAPIERRE, Don, HILL, Nolan
MSM Plasma Program 399875.0
Assessing acceptability, understanding and effectiveness of alternative screening questions for current donors Principal Investigator: FISHER, William

Co-Investigator(s) / Trainee: HAW, Jennie, GOLDMAN, Mindy, FOSTER, Terrie, O'BRIEN, Sheila, HOFKIRCHNER, Alexander
MSM Plasma Program 129400.0
Awareness and understanding of apheresis plasma donation and effectiveness of alternative donor screening questions for diverse gbMSM and trans populations Principal Investigator: GAHAGAN, Jacqueline

Co-Investigator(s) / Trainee: HAW, Jennie, LACHOWSKY, Nathan, DRYDEN, OmiSoore, MANNING, Eli, FOSTER, Terrie, O'BRIEN, Sheila, HACHETTE, Todd, MULLOWNEY, Mike
MSM Plasma Program 200500.0
Operational impact of individual risk assessment options Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: ROBILLARD, Pierre, GOLDMAN, Mindy, MYHAL, Geneviève
MSM Research Grant Program 168000.0
Évaluation de l’acceptabilité et de la faisabilité d’un programme de dons de plasma destiné au fractionnement, pour les hommes ayant des relations sexuelles avec d’autres hommes de la communauté gaie montréalaise Principal Investigator: OTIS, Joanne

Co-Investigator(s) / Trainee: GERMAIN, Marc, GODIN, Gaston, PRONOVOST, Frédérick, MONTEITH, Kenneth, MYHAL, Geneviève, GIRARD, Gabriel, MORIN, Michel
MSM Research Grant Program 229507.0
Assessing alternative Canadian Blood Services blood donor deferral screening policies for men who have sex with men Principal Investigator: BRENNAN, David

Co-Investigator(s) / Trainee: ADAM, Barry, HART, Trevor, LACHOWSKY, Nathan, GRACE, Daniel
MSM Research Grant Program 60000.0
Allowing MSM to donate in the context of pathogen reduction of blood components: mathematical modeling of the risk of HIV, HBV and HCV transmission through transfusion Principal Investigator: LEWIN, Antoine

Co-Investigator(s) / Trainee: GERMAIN, Marc, DELAGE, Gilles, ROBILLARD, Pierre, GRÉGOIRE, Yves, WILLIAM, Fraser
MSM Research Grant Program 39618.0
Safety, Acceptance, Fairness & Equality (SAFE project): Acceptable risk and donor selection Principal Investigator: DITTO, Blaine

Co-Investigator(s) / Trainee: FERGUSON, Eamonn
MSM Research Grant Program 49412.5
Mathematical Modelling – Comparing HIV Risk Between MSM Donation Strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GERMAIN, Marc, GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program 24000.0
Assessing unintentional creation of bias against MSM as a function of exposure to blood donor screening questionnaire and assessing sexual behaviour risk factors of those successfully passing blood donor screening Principal Investigator: FISHER, William

Co-Investigator(s) / Trainee:
MSM Research Grant Program 56000.0
Feasibility of implementing source plasma donation with alternative eligibility criteria for men who have sex with men Principal Investigator: PRESSEAU, Justin

Co-Investigator(s) / Trainee: GOLDMAN, Mindy, O'BRIEN, Sheila, MACPHERSON, Paul, OTIS, Joanne, GERMAIN, Marc, DEVINE, Dana, ROSSER, Andrew, LAPIERRE, Don
MSM Research Grant Program 309940.0
Attitudes, behaviours, and acceptability related to current and future blood donation policy: A qualitative study of gay, bisexual, and other men who have sex with men in Vancouver, Toronto, and Montréal Principal Investigator: GRACE, Daniel

Co-Investigator(s) / Trainee: HART, Trevor, LAMBERT, Gilles, COX, Joseph , ADAM, Barry , BRENNAN, David , LACHOWSKY, Nathan, MOORE, David
MSM Research Grant Program 60000.0
Understanding general population impact and opportunities from changes to blood donation deferral screening and criteria for men who have sex with men Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: BRENNAN, David, CARD, Kiffer, DRYDEN, OmiSoore, GASPAR, Mark, GILBERT, Mark, GRACE, Daniel, KNIGHT, Rodney, LEBOUCHÉ, Bertrand, MORGAN, Jeffrey, SALWAY, Travis
MSM Research Grant Program 310000.0
A longitudinal analysis of behavioural and biological risk among men who have sex with men in metro Vancouver Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: HOGG, Robert, MOORE, David, ROTH, Eric, ARMSTRONG, Heather
MSM Research Grant Program 50000.0
Mathematical modeling - comparing HIV risk between MSM donation strategies Principal Investigator: O'BRIEN, Sheila

Co-Investigator(s) / Trainee: GRÉGOIRE, Yves, SEED, Clive, CUSTER, Brian, STEELE, Whitney, DAVISON, Katy, PILLONEL, Josiane
MSM Research Grant Program 18000.0
ACB and MSM - it's not an oxymoron: A research project that explores the importance of ACB people in MSM blood donation research Principal Investigator: DRYDEN, OmiSoore

Co-Investigator(s) / Trainee: LEE, Woo Jin Edward, NELSON, LaRon, MARSHALL, Zack, MBUAGBAW, Lawrence
MSM Research Grant Program 410000.0
Estimating the probability of HIV risk in MSM donor policies through biobehavioural and mathematical modelling studies Principal Investigator: HART, Trevor

Co-Investigator(s) / Trainee: LAMBERT, Gilles, GRACE, Daniel, BAUER, Greta, MOORE, David, COX, Joseph, LACHOWSKY, Nathan, MISHRA, Sharmistha, BRENNAN, David, TAN, Darrell, SKAKOON-SPARLING, Shayna
MSM Research Grant Program 452500.0
Sex Now 2018: A national survey on blood donation and undiagnosed blood borne infections Principal Investigator: LACHOWSKY, Nathan

Co-Investigator(s) / Trainee: TRUSSLER, Terry, GILBERT, Mark, SALWAY, Travis, JOLLIMORE, Jody, HAM, David, LOFTUS, Patrick, OLIVER, Brent, HANSEN, Brian, VISSER, Floyd, BRENNAN, David, GRACE, Daniel, OTIS, Joanne, LEBOUCHÉ, Bertrand, NUMER, Matthew, SAXTON, Peter
MSM Research Grant Program 421719.0
Preservation of red blood cells by the novel isochoric oil-sealing supercooling system Principal Investigator: ACKER, Jason

Co-Investigator(s) / Trainee: ZHAO, Yuanheng
Postdoctoral Fellowship Program 167000.0
Role of Fc receptors in antibody-mediated immune suppression Principal Investigator: LAZARUS, Alan

Co-Investigator(s) / Trainee: BERNARDO REYES, Lidice
Postdoctoral Fellowship Program 106200.0
Identifying biomarkers for Staphylococcus aureus contamination of platelet component Principal Investigator: RAMIREZ-ARCOS, Sandra

Co-Investigator(s) / Trainee: CHI, Sylvia Ighem
Postdoctoral Fellowship Program 150000.0
DNA aptamers for detection of red blood cells destined for rapid post-transfusion clearance Principal Investigator: SHEFFIELD, William

Co-Investigator(s) / Trainee: DONKOR, David
Postdoctoral Fellowship Program 150000.0
Innovative strategies for detection of uncharacterized platelet ligands from blood plasma and autoantibodies in blood Principal Investigator: NI, Heyu

Co-Investigator(s) / Trainee: SLAVKOVIC, Sladjana
Postdoctoral Fellowship Program 162400.0
Development of a small molecule-based stem and progenitor expansion protocol to accelerate engraftment after cord blood transplantation Principal Investigator: PINEAULT, Nicolas

Co-Investigator(s) / Trainee: MANESIA, Javed
Postdoctoral Fellowship Program 101200.0