Our Funded Research Projects
Updated April 2024
| Title | Principal Investigator / Supervisor | Program Sort descending | Project Start Date | Project End Date | Total $ Awarded |
|---|---|---|---|---|---|
| Recombinant Fc multimers to replace IVIG | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: LEWIS, Bonnie |
Graduate Fellowship Program | 104000.0 | ||
| Evaluation and improvement of cold stored platelets | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: ZHAO, Hanqi (Wayne) |
Graduate Fellowship Program | 112333.3 | ||
| Mechanisms of anti-αIIb mediated miscarriage in fetal and neonatal alloimmune thrombocytopenia | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: CHEN, Zi Yan |
Graduate Fellowship Program | 52000.0 | ||
| The in vivo effects of liposome treatment on minimizing membrance injury in rat red blood cells during hypothermic storage | Principal Investigator: HOLOVATI, Jelena Co-Investigator(s) / Trainee: da SILVIERA CAVALCANTE, Luciana |
Graduate Fellowship Program | 100000.0 | ||
| Study of the mechanisms implicated in platelets microparticle internalization by blood cells | Principal Investigator: BOILARD, Eric Co-Investigator(s) / Trainee: MARCOUX, Genevieve |
Graduate Fellowship Program | 104000.0 | ||
| Anti-GPIb mediated thrombocytopenia: implications for IVIG and other therapies | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: XU, Miao |
Graduate Fellowship Program | 52000.0 | ||
| Defining the stem cell regulatory functions of GAS6 and FTO | Principal Investigator: MAGANTI, Harinad Co-Investigator(s) / Trainee: PASALA, Ajay |
Graduate Fellowship Program | 52000.0 | ||
| MRI guided focused ultrasound facilitated IVIg immunotherapy as a therapeutic approach for Alzheimer's disease | Principal Investigator: AUBERT, Isabelle Co-Investigator(s) / Trainee: DUBEY, Sonam |
Graduate Fellowship Program | 100000.0 | ||
| Dengue virus replication by anucleate cells: impact on pathogen reduction efficacy | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: FELGENHAUER, Ulrike |
Graduate Fellowship Program | 52000.0 | ||
| Deformability based cell sorting enabling quality control of stored red blood cells | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: ISLAMZADA, Emel |
Graduate Fellowship Program | 112333.0 | ||
| Generation of a coagulation factor-based thrombotic agent | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: WITT, Alexandra |
Graduate Fellowship Program | 52000.0 | ||
| Role of skin disinfection and buffy coat platelet production on residual bacterial contamination in platelet concentrates and cord blood stem cells | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: TAHA, Mariam |
Graduate Fellowship Program | 92000.0 | ||
| Platelet desialylation: novel mechanism of platelet clearance and immune tolerance | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: LI, June |
Graduate Fellowship Program | 104000.0 | ||
| A novel clot-dissolving agent derived from clotting factor Va | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: LEE, Frank |
Graduate Fellowship Program | 39500.0 | ||
| Assessing the relationship between red blood cell deformability and transfusion lifetime | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: LAMOUREUX, Erik |
Graduate Fellowship Program | 52000.0 | ||
| Characterization of the role of MSI2 in human hematopoietic stem cell self-renewal | Principal Investigator: HOPE, Kristin Co-Investigator(s) / Trainee: RENTAS, Stefan |
Graduate Fellowship Program | 100000.0 | ||
| Small molecule ice recrystallization inhibitors as cryo-additives for red blood cell cryopreservation | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: POISSON, Jessica |
Graduate Fellowship Program | 82000.0 | ||
| Monoclonal antibodies with anti-D like activity in amelioration of murine ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: KHAN, Ramsha |
Graduate Fellowship Program | 56166.7 | ||
| Modified platelet storage containers to improve quality during storage | Principal Investigator: KIZHAKKEDATHU, Jayachandran Co-Investigator(s) / Trainee: PEREYRA DOS SANTOS, Nicolas |
Graduate Fellowship Program | 52000.0 | ||
| Towards the impact of protein synthesis in human platelets to transfusion medicine | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: BOSGOED, Christa |
Graduate Fellowship Program | 92000.0 | ||
| Improving pathogen inactivation: the dengue virus-induced platelet proteome | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: TEGEGN, Tseday Zewdu |
Graduate Fellowship Program | 104000.0 | ||
| New solution for cord blood unit preservation | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: KAUSHAL, Richa |
Graduate Fellowship Program | 116500.0 | ||
| Anemia-induced bleeding in thrombocytopenic patients with blood cancer | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: MODI, Dimpy |
Graduate Fellowship Program | 70000.0 | ||
| Studies on the development of biocompatible antimicrobial platelet storage devices | Principal Investigator: BROOKS, Don Co-Investigator(s) / Trainee: HADJESFANDIARI, Narges |
Graduate Fellowship Program | 96000.0 | ||
| Novel cell-surface engineering methods to increase immune-tolerance of allogenic cell transplantation | Principal Investigator: KIZHAKKEDATHU, Jayachandran Co-Investigator(s) / Trainee: MOON, Haisle |
Graduate Fellowship Program | 90333.3 | ||
| Modulation of biofilm formation, virulence, and antimicrobial resistance by Staphylococcus aureus during platelet storage | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: SAD, Subash, MAH, Thien-Fah |
Intramural Research Grant Program | 323252.6 | ||
| Improving blood product quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: MA, Hongshen, JOHNSON, James, D'ALESSANDRO, Angelo |
Intramural Research Grant Program | 304462.0 | ||
| Monovalent Fc receptor blockade using novel fusion proteins: The road towards an IVIg replacement | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SHEFFIELD, William, BRANCH, Donald |
Intramural Research Grant Program | 400000.0 | ||
| New cryosolution for stem cell-based therapeutics | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: BEN, Robert, HARPER, Marie-Ellen, CHAKRABORTY, Nilay |
Intramural Research Grant Program | 180000.0 | ||
| Controlling coagulopathy and bleeding in a mouse model of hemorrhagic shock | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: NAZY, Ishac |
Intramural Research Grant Program | 274854.0 | ||
| Influence of eryptosis and storage on transfused red cell recovery in sepsis | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: BRANCH, Donald, LIAW, Patricia, HEDDLE, Nancy, QADRI, Syed |
Intramural Research Grant Program | 283569.0 | ||
| Enabling next generation hematopoietic-based therapeutics and manufacturing | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: MCCOMB, Scott, JEZIERSKI, Anna, MAGALHAES, Ana, IQBAL, Umer |
Intramural Research Grant Program | 300000.0 | ||
| Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy |
Intramural Research Grant Program | 200000.0 | ||
| Evaluating the role of donor characteristics and blood component manufacturing on the quality of red cell concentrates | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: BRANCH, Donald, CLARKE, Gwen, NAHIRNIAK, Susan |
Intramural Research Grant Program | 398382.8 | ||
| Assessing the impact of donor manufacturing characteristics on survival of transfused red blood cells | Principal Investigator: TINMOUTH, Alan Co-Investigator(s) / Trainee: ACKER, Jason, FERGUSSON, Dean, CHASSÉ, Michaël |
Intramural Research Grant Program | 90935.0 | ||
| Antibodies to CD44 as a potential replacement for IVIg in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SEMPLE, John W., SHEFFIELD, William |
Intramural Research Grant Program | 300000.0 | ||
| A clinical comparison of cold-stored and room temperature-stored allogeneic platelet transfusions in bleeding adult cardiac surgery patients - A randomized multicentre pilot study (PLTS-1 study) | Principal Investigator: BARTOSZKO, Justyna Co-Investigator(s) / Trainee: CALLUM, Jeannie, DEVINE, Dana, KARKOUTI, Keyvan, KAHR, Walter, MCVEY, Mark, PEER, Miki, RAO, Vivek, ABRAHAMYAN, Lusine, LIEBERMAN, Lani, MEWHORT, Holly |
Intramural Research Grant Program | 242617.0 | ||
| TAD-POL (Transfusion-Associated-Dyspnea: Prospective observation and laboratory assessment) | Principal Investigator: CSERTI-GAZDEWICH, Christine Co-Investigator(s) / Trainee: BRANCH, Donald, LAZARUS, Alan, CALLUM, Jeannie, LIN, Yulia, PENDERGRAST, Jacob, LIEBERMAN, Lani, SHEHATA, Nadine, PAVENSKI, Katerina, SKEATE, Robert |
Intramural Research Grant Program | 278027.5 | ||
| Development of porcine equivalent RCC and plasma units for translatable ex vivo organ perfusion research | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: FREED, Darren |
Intramural Research Grant Program | 121834.0 | ||
| Residual risk of transfusion-transmitted cytomegalovirus infection: incidence and pathogenesis | Principal Investigator: PREIKSAITIS, Jutta Co-Investigator(s) / Trainee: O'BRIEN, Sheila F., FEARON, Margaret, NAHIRNIAK, Susan |
Intramural Research Grant Program | 260451.0 | ||
| Fc receptor blockade in transfusion medicine | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu, GUPTA, Akash, SHEHATA, Nadine, KJELDSEN-KRAGH, Jens, NEWMAN, Peter J., CSERTI-GAZDEWICH, Christine, RAVETCH, Jeffery |
Intramural Research Grant Program | 400000.0 | ||
| Development of a small molecule cocktail for the expansion of cord blood stem cells | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: BLAKE, John, AUDET, Julie |
Intramural Research Grant Program | 237600.0 | ||
| PREMISE: Point-of-care hemoglobin accuracy and transfusion outcomes in non-cardiac surgery | Principal Investigator: MARTEL, Guillaume Co-Investigator(s) / Trainee: TINMOUTH, Alan, FERGUSSON, Dean, MCISAAC, Daniel, SHAW, Julie, RAMSAY, Tim, PRESSEAU, Justin, WHERRETT, Christopher, CARRIER, François-Martin, SEELY, Andrew, BRYSON, Gregory |
Intramural Research Grant Program | 392974.0 | ||
| Monoclonal antibodies with anti-D-like activity in the amelioration of murine immune thrombocytopenia (ITP) | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SEMPLE, John W., NI, Heyu |
Intramural Research Grant Program | 400000.0 | ||
| Elucidation of the mechanism of IVIG-associated hemolysis | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: PENDERGRAST, Jacob , CSERTI-GAZDEWICH, Christine , SHEHATA, Nadine , PAVENSKI, Katerina , LAU, Wendy , CALLUM, Jeannie , LIN, Yulia , LIEBERMAN, Lani , HANNACH, Barbara |
Intramural Research Grant Program | 393712.0 | ||
| Small molecule inhibitors of phagocytosis | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: KOTRA, Lakshmi P. |
Intramural Research Grant Program | 399130.0 | ||
| Plasma transfusion or plasma protein product infusion in a murine model of trauma | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: PRYZDIAL, Edward |
Intramural Research Grant Program | 257414.8 | ||
| Anti-RBC monoclonal antibodies as a replacement for IVIg and anti-D in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: BRANCH, Donald, DUNN, Shannon |
Intramural Research Grant Program | 400000.0 | ||
| Role of blood component manufacturing on microvesicle-induced transfusion-related immune modulation | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: HOLOVATI, Jelena, BRANCH, Donald, ZHANG, Haibo |
Intramural Research Grant Program | 250660.0 | ||
| Defining the components of transfusable plasma that reduce bleeding | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: PRYZDIAL, Edward, NI, Heyu |
Intramural Research Grant Program | 218230.0 |