Our Funded Research Projects
Updated April 2024
| Title | Principal Investigator / Supervisor | Program Sort descending | Project Start Date | Project End Date | Total $ Awarded |
|---|---|---|---|---|---|
| Perioperative transfusion threshold : A population-based observational study | Principal Investigator: FERGUSSON, Dean Co-Investigator(s) / Trainee: VERRET, Michael |
Graduate Fellowship Program | 52000.0 | ||
| Small molecule inhibitors of phagocytosis to replace intravenous immunoglobulin (IVIG) | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: TONG, Tik Nga (Cindy) |
Graduate Fellowship Program | 52000.0 | ||
| Investigating a new class of small molecule ice recrystallization inhibitors for red blood cell cryopreservation | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: AMPAW, Anna |
Graduate Fellowship Program | 112333.3 | ||
| Identification of protein biomarkers for red cell quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: CHEN, Deborah |
Graduate Fellowship Program | 100000.0 | ||
| Donor factors and product quality | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: YAZDANBAKHSH, Mahsa |
Graduate Fellowship Program | 122000.0 | ||
| Recombinant Fc multimers to replace IVIG | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: LEWIS, Bonnie |
Graduate Fellowship Program | 104000.0 | ||
| Evaluation and improvement of cold stored platelets | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: ZHAO, Hanqi (Wayne) |
Graduate Fellowship Program | 112333.3 | ||
| The in vivo effects of liposome treatment on minimizing membrance injury in rat red blood cells during hypothermic storage | Principal Investigator: HOLOVATI, Jelena Co-Investigator(s) / Trainee: da SILVIERA CAVALCANTE, Luciana |
Graduate Fellowship Program | 100000.0 | ||
| Mechanisms of anti-αIIb mediated miscarriage in fetal and neonatal alloimmune thrombocytopenia | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: CHEN, Zi Yan |
Graduate Fellowship Program | 52000.0 | ||
| Study of the mechanisms implicated in platelets microparticle internalization by blood cells | Principal Investigator: BOILARD, Eric Co-Investigator(s) / Trainee: MARCOUX, Genevieve |
Graduate Fellowship Program | 104000.0 | ||
| Anti-GPIb mediated thrombocytopenia: implications for IVIG and other therapies | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: XU, Miao |
Graduate Fellowship Program | 52000.0 | ||
| MRI guided focused ultrasound facilitated IVIg immunotherapy as a therapeutic approach for Alzheimer's disease | Principal Investigator: AUBERT, Isabelle Co-Investigator(s) / Trainee: DUBEY, Sonam |
Graduate Fellowship Program | 100000.0 | ||
| Defining the stem cell regulatory functions of GAS6 and FTO | Principal Investigator: MAGANTI, Harinad Co-Investigator(s) / Trainee: PASALA, Ajay |
Graduate Fellowship Program | 52000.0 | ||
| Dengue virus replication by anucleate cells: impact on pathogen reduction efficacy | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: FELGENHAUER, Ulrike |
Graduate Fellowship Program | 52000.0 | ||
| Deformability based cell sorting enabling quality control of stored red blood cells | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: ISLAMZADA, Emel |
Graduate Fellowship Program | 112333.0 | ||
| Role of skin disinfection and buffy coat platelet production on residual bacterial contamination in platelet concentrates and cord blood stem cells | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: TAHA, Mariam |
Graduate Fellowship Program | 92000.0 | ||
| Generation of a coagulation factor-based thrombotic agent | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: WITT, Alexandra |
Graduate Fellowship Program | 52000.0 | ||
| Platelet desialylation: novel mechanism of platelet clearance and immune tolerance | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: LI, June |
Graduate Fellowship Program | 104000.0 | ||
| A novel clot-dissolving agent derived from clotting factor Va | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: LEE, Frank |
Graduate Fellowship Program | 39500.0 | ||
| Characterization of the role of MSI2 in human hematopoietic stem cell self-renewal | Principal Investigator: HOPE, Kristin Co-Investigator(s) / Trainee: RENTAS, Stefan |
Graduate Fellowship Program | 100000.0 | ||
| Assessing the relationship between red blood cell deformability and transfusion lifetime | Principal Investigator: MA, Hongshen Co-Investigator(s) / Trainee: LAMOUREUX, Erik |
Graduate Fellowship Program | 52000.0 | ||
| Small molecule ice recrystallization inhibitors as cryo-additives for red blood cell cryopreservation | Principal Investigator: BEN, Robert Co-Investigator(s) / Trainee: POISSON, Jessica |
Graduate Fellowship Program | 82000.0 | ||
| Monoclonal antibodies with anti-D like activity in amelioration of murine ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: KHAN, Ramsha |
Graduate Fellowship Program | 56166.7 | ||
| Towards the impact of protein synthesis in human platelets to transfusion medicine | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: BOSGOED, Christa |
Graduate Fellowship Program | 92000.0 | ||
| Modified platelet storage containers to improve quality during storage | Principal Investigator: KIZHAKKEDATHU, Jayachandran Co-Investigator(s) / Trainee: PEREYRA DOS SANTOS, Nicolas |
Graduate Fellowship Program | 52000.0 | ||
| Small molecule drug development of phagocytosis inhibitors | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: KOTRA, Lakshmi, P. |
Intramural Research Grant Program | 428468.4 | ||
| Translating novel clotting factor X function to treat thrombosis | Principal Investigator: PRYZDIAL, Ed Co-Investigator(s) / Trainee: MACVICAR, Brian, SHEFFIELD, William |
Intramural Research Grant Program | 369052.0 | ||
| Human monoclonal CD44 antibodies as potential IVIg replacements | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu |
Intramural Research Grant Program | 336000.0 | ||
| Anti-GPIb- and anti-GPIIbIIIa- mediated immune thrombocytopenia: Mechanisms and actions of intravenous IgG (IVIG) and alternative therapies | Principal Investigator: NI, Heyu Co-Investigator(s) / Trainee: LAZARUS, Alan, BRANCH, Donald |
Intramural Research Grant Program | 412010.3 | ||
| Revisiting the universal donor: Does exposure to O blood products affect patient outcomes? | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: ACKER, Jason, BUCKSTEIN, Rena, CALLUM, Jeannie, COOK, Richard, HEDDLE, Nancy, SOLH, Ziad, WEBERT, Kathryn, BARTY, Rebecca, LEBER, Brian, LALIT, Saini |
Intramural Research Grant Program | 378365.0 | ||
| Plasma versus plasma protein concentrate transfusion for coagulopathic control | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: NI, Heyu |
Intramural Research Grant Program | 224417.0 | ||
| Fc receptors and IVIg in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, LIN, Yulia, CALLUM, Jeannie, SHOLZBERG, Michelle, NI, Heyu |
Intramural Research Grant Program | 432000.0 | ||
| Mechanisms of erythrocyte antibody-mediated immune suppression | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu, SEMPLE, John |
Intramural Research Grant Program | 400000.0 | ||
| A multifaceted intervention to optimize red blood cell transfusion practice in two provinces | Principal Investigator: WEBERT, Kathryn Co-Investigator(s) / Trainee: NAHIRNIAK, Susan, CALLUM, Jeannie, LIN, Yulia, ZELLER, Michelle |
Intramural Research Grant Program | 332942.0 | ||
| IN-TRUST: Using a transfusion database to explore the immune-modulatory impacts of blood transfusion and the clinical impacts of blood processing changes | Principal Investigator: NING, Shuoyan Co-Investigator(s) / Trainee: ARNOLD, Donald, ZELLER, Michelle, ACKER, Jason, LI, Na, HEDDLE, Nancy, HILLIS, Christopher, ROCHWERG, Bram, SYED, Summer |
Intramural Research Grant Program | 270352.1 | ||
| RBC hemolysis and cellular effector mechanisms (RHANCEM) | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: CSERTI-GAZDEWICH, Christine, PENDERGRAST,Jacob, CALLUM, Jeannie, YI, Qilong |
Intramural Research Grant Program | 399927.3 | ||
| Optimization of monoclonal anti-erythrocyte antibodies for improved immunoprophylaxis in a murine model | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: NI, Heyu |
Intramural Research Grant Program | 400000.0 | ||
| Modulation of biofilm formation, virulence, and antimicrobial resistance by Staphylococcus aureus during platelet storage | Principal Investigator: RAMIREZ-ARCOS, Sandra Co-Investigator(s) / Trainee: SAD, Subash, MAH, Thien-Fah |
Intramural Research Grant Program | 323252.6 | ||
| Improving blood product quality | Principal Investigator: DEVINE, Dana Co-Investigator(s) / Trainee: MA, Hongshen, JOHNSON, James, D'ALESSANDRO, Angelo |
Intramural Research Grant Program | 304462.0 | ||
| Antibodies to CD44 as a potential replacement for IVIg in ITP | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SEMPLE, John W., SHEFFIELD, William |
Intramural Research Grant Program | 300000.0 | ||
| Monovalent Fc receptor blockade using novel fusion proteins: The road towards an IVIg replacement | Principal Investigator: LAZARUS, Alan Co-Investigator(s) / Trainee: SHEFFIELD, William, BRANCH, Donald |
Intramural Research Grant Program | 400000.0 | ||
| New cryosolution for stem cell-based therapeutics | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: BEN, Robert, HARPER, Marie-Ellen, CHAKRABORTY, Nilay |
Intramural Research Grant Program | 180000.0 | ||
| Controlling coagulopathy and bleeding in a mouse model of hemorrhagic shock | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: NAZY, Ishac |
Intramural Research Grant Program | 274854.0 | ||
| Residual risk of transfusion-transmitted cytomegalovirus infection: incidence and pathogenesis | Principal Investigator: PREIKSAITIS, Jutta Co-Investigator(s) / Trainee: O'BRIEN, Sheila F., FEARON, Margaret, NAHIRNIAK, Susan |
Intramural Research Grant Program | 260451.0 | ||
| Influence of eryptosis and storage on transfused red cell recovery in sepsis | Principal Investigator: SHEFFIELD, William Co-Investigator(s) / Trainee: BRANCH, Donald, LIAW, Patricia, HEDDLE, Nancy, QADRI, Syed |
Intramural Research Grant Program | 283569.0 | ||
| Enabling next generation hematopoietic-based therapeutics and manufacturing | Principal Investigator: PINEAULT, Nicolas Co-Investigator(s) / Trainee: MCCOMB, Scott, JEZIERSKI, Anna, MAGALHAES, Ana, IQBAL, Umer |
Intramural Research Grant Program | 300000.0 | ||
| Biomarkers in patients with anemia-induced thrombocytopenic bleeding (BAIT): A pilot study | Principal Investigator: ARNOLD, Donald Co-Investigator(s) / Trainee: WEBERT, Kathryn, LIAW, Patricia, BERG, Tobias, HEDDLE, Nancy |
Intramural Research Grant Program | 200000.0 | ||
| Elucidation of the mechanism of IVIG-associated hemolysis | Principal Investigator: BRANCH, Donald Co-Investigator(s) / Trainee: PENDERGRAST, Jacob , CSERTI-GAZDEWICH, Christine , SHEHATA, Nadine , PAVENSKI, Katerina , LAU, Wendy , CALLUM, Jeannie , LIN, Yulia , LIEBERMAN, Lani , HANNACH, Barbara |
Intramural Research Grant Program | 393712.0 | ||
| Evaluating the role of donor characteristics and blood component manufacturing on the quality of red cell concentrates | Principal Investigator: ACKER, Jason Co-Investigator(s) / Trainee: BRANCH, Donald, CLARKE, Gwen, NAHIRNIAK, Susan |
Intramural Research Grant Program | 398382.8 | ||
| Assessing the impact of donor manufacturing characteristics on survival of transfused red blood cells | Principal Investigator: TINMOUTH, Alan Co-Investigator(s) / Trainee: ACKER, Jason, FERGUSSON, Dean, CHASSÉ, Michaël |
Intramural Research Grant Program | 90935.0 |