Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
T cell-mediated autoimmunity in immune thrombocytopenia Vrbensky JR, Nazy I, Clare R, Larché M, Arnold DM 2022 Eur J Haematol View Researchers Clinical research
Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia Arnold DM, Nazi I, Toltl LJ, Ross C, Ivetic N, Smith JW, Liu Y, Kelton JG 2015 Eur J Haematol View Researchers Clinical research
A blinded study of bone marrow examinations in patients with primary immune thrombocytopenia Mahabir VK, Ross C, Popovic S, Sur ML, Bourgeois J, Lim W, George JN, Wang G, Cook RJ, Toltl LJ, Nazi I, Kelton JG, Arnold DM 2013 Eur J Haematol View Health care providers Clinical research
Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A Astermark J, Olsson A, Chelle P, Täckström K, Walger M, Magnusson M, Iorio A 2021 Haemophilia View Researchers Clinical research
Comorbidities in persons with haemophilia aged 60 years or more compared with age-matched people from the general population Marchesini E, Oliovecchio E, Coppola A, Santagostino E, Radossi P, Castaman G, Valdre L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Iorio A, Mannucci PM 2018 Haemophilia View Health care providers Clinical research
Understanding stakeholder important outcomes and perceptions of equity, acceptability and feasibility of a care model for haemophilia management in the US: a qualitative study Lane SJ, Sholapur NS, Yeung CH, Iorio A, Heddle NM, Sholzberg M, Pai M 2016 Haemophilia View Health care providers Other
A brief survey of clinicians' perceptions of parent preferences for involvement in obstetrical and perinatal management decisions in haemophilia Lucier KJ, Movilla RV, Parvizian MK, Siddiqui R, Gabriele EH, Bourque M, MacIsaac J, Moorehead PC, Chan AK, Heddle NM, Lane SJ 2018 Haemophilia View Health care providers Clinical research
Target plasma factor levels for personalized treatment in haemophilia: a Delphi consensus statement Iorio A, Iserman E, Blanchette V, Dolan G, Escuriola Ettingshausen C, Hermans C, Negrier C, Oldenburg J, Reininger A, Rodriguez-Merchan C, Spannagl M, Valentino LA, Young G, Steinitz-Trost KN, Gringeri A 2017 Haemophilia View Health care providers Clinical research
Patterns of joint damage in severe haemophilia A treated with prophylaxis Goren R, Pullenayegum E, Blanchette VS, Dover S, Carcao M, Israels SJ, Chan A, Rivard GE, Steele M, Cloutier S, Klaassen RJ, Sinha R, Price VE, Laferriere N, Paradis E, Wu JK, Feldman BM 2021 Haemophilia View Health care providers Clinical research
A systematic review of definitions and reporting of bleeding outcome measures in haemophilia Chai-Adisaksopha C, Hillis C, Thabane L, Iorio A 2015 Haemophilia View Health care providers Clinical research
First analysis of 10-year trends in national factor concentrates usage in haemophilia: data from CHARMS, the Canadian Hemophilia Assessment and Resource Management System Traore AN, Chan AKC, Webert KE, Heddle N, Ritchie B, St-Louis J, Teitel J, Lillicrap D, Iorio A, Walker I 2014 Haemophilia View Health care providers Clinical research
Sexual issues in people with haemophilia: Awareness and strategies for overcoming communication barriers Blamey G, Van Tassel B, Sagermann E, Stain AM, Waterhouse L, Iorio A 2022 Haemophilia View Researchers Ethical, legal and social implications research
What should men living with haemophilia need to know? The perspectives of Canadian men with haemophilia Arnold E, Lane S, Webert KE, Chan A, Walker I, Tufts J, Rubin S, Poon MC, Heddle NM 2014 Haemophilia View Health care providers Other
Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study Liesner RJ, Abashidze M, Aleinikova O, Altisent C, Belletrutti MJ, Borel-Derlon A, Carcao M, Chambost H, Chan AKC, Dubey L, Ducore J, Fouzia NA, Gattens M, Gruel Y, Guillet B, Kavardakova N, El Khorassani M, Klukowska A, Lambert T, Lohade S, Sigaud M, Turea V, Wu JKM, Vdovin V, Pavlova A, Jansen M, Belyanskaya L, Walter O, Knaub S, Neufeld EJ 2017 Haemophilia View Researchers Clinical research
Prophylaxis use of clotting factor replacement products in people with non-severe haemophilia: A review of the literature Iorio A, Königs C, Reding MT, Rotellini D, Skinner MW, Mancuso ME, Berntorp E 2023 Haemophilia View Health care providers Clinical research
What should men living with severe haemophilia need to know? The perspectives of Canadian haemophilia health care providers Lane S, Arnold E, Webert KE, Chan A, Walker I, Heddle NM 2013 Haemophilia View Health care providers Other
Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomes Pierce GF, Iorio A 2018 Haemophilia View Health care providers New or improved product or process
Factor product utilization and health outcomes in patients with haemophilia A and B on extended half-life concentrates: A Canadian observational study of real-world outcomes Sun H, Yang M, Poon M-C, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S 2021 Haemophilia View Researchers Clinical research
Switching to extended half-life products in Canada - preliminary data Keepanasseril A, Stoffman J, Bouskill V, Carcao M, Iorio A, Jackson S 2017 Haemophilia View Health care providers Clinical research
Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A 2019 Haemophilia View Researchers Clinical research
Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach Lane SJ, Walker I, Chan AK, Heddle NM, Poon MC, Minuk L, Jardine L, Arnold E, Sholapur N, Webert KE 2015 Haemophilia View Health care providers Clinical research
Converting factor and nonfactor usage into a single metric to facilitate benchmarking the resources consumed for haemophilia care across jurisdictions and over time Stonebraker JS, O'Mahony B, Noone D, Iorio A 2021 Haemophilia View Researchers Benchmarking and standard setting
Evaluation of the sexual health in people living with hemophilia Germini F, Chai-Adisaksopha C, Pete D, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker JS, Thabane L, Crowther MA, Skinner MW, Iorio A 2021 Haemophilia View Researchers Clinical research
The importance of haemophilia treatment centre administrators in patient care Almonte T, Decker K, Seroski W, Walker I, Webert K, Bos C, Strike K, Waterhouse L, Goldsmith R, Chan AK 2012 Haemophilia View Health care providers Other
Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company Hay CRM, Shima M, Makris M, Jiménez-Yuste V, Oldenburg J, Fischer K, Iorio A, Skinner MW, Santagostino E, von Mackensen S, Kessler CM 2020 Haemophilia View Researchers Clinical research
Rate and appropriateness of polypharmacy in older patients with hemophilia compared with age-matched controls Mannucci PM, Nobili A, Marchesini E, Oliovecchio E, Cortesi L, Coppola A, Santagostino E, Radossi P, Castaman G, Valdrè L, Santoro C, Tagliaferri A, Ettorre C, Zanon E, Barillari G, Cantori I, Caimi TM, Sottilotta G, Peyvandi F, Iorio A 2018 Haemophilia View Health care providers Clinical research
Exploring some intersections between pharmacokinetics, factor VIII measurement and human morphometrics - impact of recent advances in haemophilia study design on our understanding of optimal haemophilia treatment Iorio A, Edginton AN 2017 Haemophilia View Researchers Clinical research
Point of care ultrasound in haemophilia: Building a strong foundation for clinical implementation Lawson W, Uy M, Strike K, Iorio A, Stein N, Koziol L, Chan A 2017 Haemophilia View Health care providers Clinical research
Emicizumab state-of-the-art update Mahlangu J, Iorio A, Kenet G 2022 Haemophilia View Health care providers Clinical research
Switching from standard to extended half-life FVIII prophylaxis in haemophilia A: Comparison of factor product use, bleed rates and pharmacokinetics Nummi V, Lehtinen AE, Iorio A, Szanto T, Lassila R 2022 Haemophilia View Researchers Clinical research
Core outcome set for gene therapy in haemophilia: Results of the coreHEM multistakeholder project Iorio A, Skinner MW, Clearfield E, Messner D, Pierce GF, Witkop M, Tunis S 2018 Haemophilia View Health care providers Clinical research
A case of vertical transmission of Chagas Disease contracted via blood transfusion in Canada Fearon MA, Scalia V, Huang M, Dines I, Ndao M 2013 Can J Infect Dis Med Microbiol View Health care providers Clinical research
One step closer': Acceptability of a programme of plasma donation for fractionation from men who have sex with men Caruso J, Germain M, Godin G, Myhal G, Pronovost P, Morin M, Otis J 2019 Vox Sang View Blood operators Other
Serologic assessments in acute transfusion reactions: practices and yields Cohen R, Lima A, Escorcia A, Tasmin F, Lin Y, Lieberman L, Pendergrast J, Callum J, Cserti-Gazdewich C 2019 Vox Sang View Health care providers Clinical research
An open-source python library for detection of known and novel Kell, Duffy and Kidd variants from exome sequencing Montemayor C, Simone A, Long J, Montemayor O, Delvadia B, Rivera R, Lewis KL, Shahsavari S, Gandla D, Dura K, Krishnan US, Wendzel NC, Elavia N, Grissom S, Karagianni P, Bueno M, Loy D, Cacanindin R, McLaughlin S, Tynuv M, Brunker PAR, Roback J, Adams S, Smith H, Biesecker L, Klein HG 2021 Vox Sang View Health care providers New or improved product or process
Evolving policies for donors with diabetes: The Canadian experience Miller O, Caffrey N, O'Brien SF, Goldman M 2022 Vox Sang View Researchers New or improved product or process
Donor deferral policies for men who have sex with men: past, present and future Goldman M, Shih AW, O'Brien SF, Devine D 2018 Vox Sang View Health care providers MSM research
Transfusion-related alloimmunization in children: epidemiology and effects of chemotherapy Solh Z, Athale U, Arnold DM, Cook RJ, Foley R, Heddle NM 2016 Vox Sang View Health care providers Clinical research
Current status of rapid bacterial detection methods for platelet components: A 20-year review by the ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria Schmidt M, Ramirez-Arcos S, Stiller L, McDonald C, ISBT Transfusion-Transmitted Infectious Diseases Working Party Subgroup on Bacteria 2022 Vox Sang View Researchers Benchmarking and standard setting
Adhesion of anaerobic bacteria to platelet containers Kumaran D, Kalab M, Rood IGH, de Korte D, Ramirez-Arcos S 2014 Vox Sang View Blood operators Basic research
International Forum on the Management of Major Haemorrhage: Summary Green L, Stanworth S, McQuilten Z, Lin V, Tucker H, Jackson B, Badawi M, Hindawi S, Chaurasia R, Patidar G, Pandey HC, Fasola F, Miyata S, Matsumoto M, Matsushita T, Rahimi-Levene N, Peer V, Pavenski K, Callum J, Thompson T, Murphy M, Staves J, Maegele M, Abeyakoon C, Rushford K, Wood E, Nuñez MA, Mellado S, Saa E, Triyono T, Pratomo B, Apelseth TO, Dunbar N 2022 Vox Sang View Health care providers Benchmarking and standard setting
Bacterial growth in red blood cell units exposed to uncontrolled temperatures: challenging the 30-minute rule Ramirez-Arcos S, Perkins H, Kou Y, Mastronardi C, Kumaran D, Taha M, Yi QL, McLaughlin N, Kahwash E, Lin Y, Acker J 2013 Vox Sang View Regulators New or improved product or process
Sex-mismatched red blood cell transfusions and mortality: A systematic review and meta-analysis Zeller MP, Rochwerg B, Jamula E, Li N, Hillis C, Acker JP, Runciman RJR, Lane SJ, Ahmed N, Arnold DM, Heddle NM 2019 Vox Sang View Researchers Clinical research
International Forum on Gender Identification and Blood Collection: Summary Pandey S, Gorlin JB, Townsend M, Van Buren N, Leung JNS, Lee CK, van den Hurk K, Casamitjana N, Valles R, Alonso E, Miller YM, Richard P, Woimant G, Tiberghien P, Zhiburt E, Butler-Foster T, Goldman M, Nissen-Meyer LSH, Espinosa A, Kamel H, Bravo M, Filho LA, Pecego M, Germain M, Rabusseau I, Shinar E, Raz H, Choudhury N, Bhatnagar N, Hurt K, Lopez M, Reik RA, Nie Y, Hung Y, Pheello L, Dunbar N 2022 Vox Sang View Blood operators Benchmarking and standard setting
Experiences with semi-routine production of riboflavin and UV-B pathogen-inactivated platelet concentrates in three blood centres van der Meer PF, Couture C, Hervig T, Kruit G, Devine DV, de Korte D, Kerkhoffs JL 2017 Vox Sang View Blood operators New or improved product or process
Hepatitis E Petrik J, Lozano M, Seed CR, Faddy HM, Keller AJ, Prado Scuracchio PS, Wendel S, Andonov A, Fearon M, Delage G, Zhang J, Shih JWK, Gallian P, Djoudi R, Tiberghien P, Izopet J, Dreier J, Vollmer T, Knabbe C, Aggarwal R, Goel A, Ciccaglione AR, Matsubayashi K, Satake M, Tadokoro K, Jeong S-H, Zaaijer HL, Zhiburt E, Chay J, Teo D, Chua SS, Piron M, Sauleda S, Echevarría J-M, Dalton H, Stramer SL 2016 Vox Sang View Blood operators Other
Determinants of the intention to participate in a programme of plasma donation for fractionation among men who have sex with men Veillette-Bourbeau L, Otis J, Lewin A, Godin G, Germain M, Daunais-Laurin G, Lalonde F, Caruso J, Myhal G, Pronovost F 2021 Vox Sang View Researchers MSM research
Reducing the age of transfused red blood cells in hospitals: ordering and allocation policies Sarhangian V, Abouee-Mehrizi H, Baron O, Berman O, Heddle NM, Barty R 2016 Vox Sang View Health care providers Benchmarking and standard setting
Targeted recruitment of male donors for allogeneic haematopoietic cell transplantation: A review of the evidence Fingrut W, Rikhraj K, Allan D 2018 Vox Sang View Blood operators Clinical research
The impact of red blood cell manufacturing variables on bacterial growth dynamics: a pilot study Ramirez-Arcos S, Kou Y, Cayer M-P, De Grandmont M-J, Girard M, Cloutier M 2019 Vox Sang View Researchers Basic research